Weekly Breaking Research Updates, June 22, 2015

Weekly Breaking Research Updates, June 22, 2015

Weekly Breaking Research Updates

Scientific breakthroughs happen every day!  In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates.  The title of each article below is a link to the full study report.  If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.

 

Ketamine

 

Ketamine and Phencyclidine: the good, the bad and the unexpected

D Lodge, MS Mercier – British Journal of Pharmacology, 2015

ABSTRACT: The history of ketamine and phencyclidine from their development as potential

clinical anaesthetics, through drugs of abuse and animal models of schizophrenia to

potential rapidly acting antidepressants is reviewed. The discovery in 1983 of the NMDA

 

Intra‐and postoperative low‐dose ketamine for adolescent idiopathic scoliosis surgery: a randomized controlled trial

R Minoshima, S Kosugi, D Nishimura, N Ihara, H Seki… – Acta Anaesthesiologica …, 2015

Background In this randomized controlled trial, we examined whether intra-and

postoperative infusion of low-dose ketamine decreased postoperative morphine

requirement and morphine-related adverse effects as nausea and vomiting after scoliosis

 

Period Prevalence of Ketamine-Propofol Admixture “Ketofol” in the Operating Room among Anesthesia Providers at an Academic Medical Center

AN Olson, WR Rao, ME Marienau, NJ Smischney – Medical Science Monitor, 2015

BACKGROUND: The primary aim of this study was to determine the period prevalence of the

single-syringe ketamine-propofol admixture used for sedation and induction among

anesthesia providers during a 5-year period before and after educational sessions

 

Electrochemiluminescence immunosensor for ketamine detection based on polyamidoamine-coated carbon dot film

Q Li, W Tang, Y Wang, J Di, J Yang, Y Wu – Journal of Solid State Electrochemistry, 2015

Abstract In this work, we reported the synthesis of water-soluble carbon dots (CDs) by a one-

step hydrothermal synthetic route using polyamidoamine (PAMAM) as platform and

passivant, where the formation of CDs capped with PAMAM and the surface passivation

 

Letter to the editor: When what you see might not be what you get: prudent considerations of anesthetics for murine echocardiography

J Wu, J You, S Wang, Y Ye, X Wang, J Jia, Y Zou – American Journal of Physiology- …, 2015

In their well- designed experiments, the authors compared four popular an- esthetic regimens

(ketamine-xylazine, ketamine alone, avertin, and isoflurane) used in mice during

echocardiographic mea- surement, with conscious state as a reference.

 

Ketamine promotes inflammation through increasing TLR4 expression in RAW264. 7 cells

C Meng, Z Liu, G Liu, L Fu, M Zhang, Z Zhang, H Xia… – Journal of Huazhong …, 2015

Summery Ketamine (KTM), a N-methyl-D-aspartate (NMDA) receptor antagonist, was found

to has an anti-inflammatory effect, but some patients suffered from exacerbated pro-

inflammatory reactions after anesthesia with KTM. The present study was aimed to

 

The effect of NMDA receptor antagonists and antidepressants on resting state in major depressive disorder

A Dutta – 2015

fMRI ; major depressive disorder ; resting state ; antidepressant ; lanicemine ; ketamine ; citalopram

; anterior cingulate cortex ; NMDA ; glutamate. Ketamine and other NMDA antagonists have

improved MDD symptoms within 24 hours though the effects are short lasting.

 

Assessing Measures of Suicidal Ideation in Clinical Trials with a Rapid-Acting Antidepressant

ED Ballard, DA Luckenbaugh, EM Richards, TL Walls… – Journal of Psychiatric …, 2015

Received 22 April 2015, Revised 21 May 2015, Accepted 5 June 2015, Available online 16 June

2015. Highlights. • Clinical trials of ketamine and suicide will require appropriate measurement. •

We compared several suicide assessment measures in ketamine clinical trials. •

 

d-Cycloserine

AR Durrant, U Heresco-Levy – Encyclopedia of Psychopharmacology, 2015

of this concept became evident during the last decade when robust antidepressant effects

emerging within 2–4 h and lasting up to more than 2 weeks were obtained and replicated fol-

lowing intravenous administration of single sub-anesthetic doses of ketamine (Krystal et al.

 

Depression: Response and Remission

SD Østergaard, GI Papakostas, M Fava – Encyclopedia of Psychopharmacology, 2015

of this concept became evident during the last decade when robust antidepressant effects

emerging within 2–4 h and lasting up to more than 2 weeks were obtained and replicated fol-

lowing intravenous administration of single sub-anesthetic doses of ketamine (Krystal et al.

 

Is pre-emptive administration of ketamine a significant adjunction to intravenous morphine analgesia for controlling postoperative pain? A randomized, double-blind, …

A Fiorelli, A Mazzella, B Passavanti, P Sansone… – … and Thoracic Surgery, 2015

OBJECTIVES To evaluate if the pre-emptive administration of ketamine would potentiate the

effect of intravenous morphine analgesia in the management of post-thoracotomy pain.

METHODS This was a unicentre, double-blind, placebo-controlled, parallel-group,

 

Kappa-Opioid Agonists

E Opioid – 2015

It is considered a precancerous condition. Ketamine Synonyms Ketalar; Ketaset Definition

Ketamine is an FDA-approved medication for induction and maintenance of anesthesia

in adults. It is a phencyclidine derivative first synthetized in 1962.

 

Investigation of the effects of stress on some liver enzymes (AST, ALT, ALP) in rats.

YG Gencer, A Çınar, B Comba – Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 2015

was applied intraperitoneally (ip) to the experimental group. After 3 h, blood samples

were collected from both groups under ketamine anaesthesia, using appropriate

techniques. The control group serum AST, ALT, ALP values

 

Back to the Future: Are Tumor-Targeting Bacteria the Next-Generation Cancer Therapy?

RM Hoffman – Gene Therapy of Solid Cancers, 2015

7. Anesthetic reagents (ketamine, xylazine, acepromazine maleate). 8. Kanamycin. 9. Nair. 10.

1. Four-week-old female mice were anesthetized by a ketamine mixture (10 μl ketamine HCL,

7.6 μl xylazine, 2.4 μl acepromazine maleate, and 10 μl H 2 O) via sc injection.

 

[PDF] The Protective Effect of Melatonin vs. Vitamin E in the Ischemic/Reperfused Skeletal Muscle in the Adult Male Rat Model

EA Mohamed – J Cytol Histol S, 2015

All surgical procedures were performed under anesthesia with IP injection of

Ketamine hydrochloride (Ketame, Egyptian Int. Co. After 2 hours of reperfusion, the

rats were sacrificed by Ketamine hydrochloride (100 mg/kg) [10].

 

[PDF] CORM2 protects from myocardial ischemia reperfusion injury via modulation of the inflammatory response and apoptosis

NR Hadi, FG Al-Amran, KA Muhsin, A Taher – Journal of Advanced Pharmacy …, 2015

2% vials (RompunTM, Bayer AG, Leverkusen, Germany), ketamine (Hikma, Jordan), ethanol

(Fluka, Switzerland) and normal saline (KSA). Rat (IL-1β), (IL- Surgical LAD ligation The rats were

anesthetized by intraperitoneal injection with a mixture of ketamine and xylazine in a

 

[HTML] Long-term correlation of the electrocorticogram as a bioindicator of brain exposure to ionizing radiation

LAA Aguiar, IMS Silva, TS Fernandes, RA Nogueira – Brazilian Journal of Medical and …, 2015

The irradiation was carried out with the animals anesthetized with 10 mg/kg xylazine and 75

mg/kg ketamine administered intraperitoneally. To record the ECoG, animals were anesthetized

with 10 mg/kg xylazine and 75 mg/kg ketamine administered intraperitoneally.

 

[HTML] The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor

SM de Melo, S Bittencourt, EG Ferrazoli, CS da Silva… – PLOS ONE, 2015

The animals were anesthetized via the ip injection of a ketamine (100 mg/kg) and xylazine

(10 mg/kg) solution (Syntec, 1356009 and 1720407) and fastened to a stereotaxic

instrument (David Kopf) equipped with a mouse adapter (Enlaup).

 

[HTML] Intrarectal Lidocaine-Diltiazem-Meperidine Gel for Transrectal Ultrasound Guided Prostate Biopsy

F Imani, Y Moghaddam, RS Moharari, F Etezadi… – Anesthesiology and Pain …, 2015

4, 6) or bupivacaine as a single agent (7). These latter studies have suggested that rectal

administration of lidocaine gel is a safe, simple modality, without any discomfort for patients (8).

Not only local anesthetic agents but also intravenous anesthetic drugs (ketamine) (9) or

 

[PDF] Alcohol Withdrawal Syndrome: Improving Outcomes Through Early Identification And Aggressive Treatment Strategies

AF Pizon – 2015

Page 1. June 2015 Volume 17, Number 6 Authors Joseph H. Yanta, MD Medical

Toxicology Fellow, Division of Medical Toxicology, Dept. of Emer- gency Medicine,

University of Pittsburgh Medical Center, Pittsburgh, PA Greg

 

Radiofrequency Ablation (RFA)

 

Use of Contact Force Sensing Technology During Radiofrequency Ablation Reduces Recurrence of Atrial Fibrillation: A Systematic Review and Meta-Analysis

MR Afzal, J Chatta, A Samanta, S Waheed… – Heart Rhythm, 2015

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Comparison of Surgical Resection and Radiofrequency Ablation for Hepatocellular Carcinoma: Take Care Not to Neglect Radiofrequency Technic and Device.

A Hocquelet, M Montaudon, P Balageas, N Frulio… – Annals of Surgery, 2015

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your privacy and will not share your personal information without your express consent. For more

information, please refer to our Privacy Policy. Skip Navigation Links Home >

 

Effect of different ablation settings on acute complications using the novel irrigated multipolar radiofrequency ablation catheter (nMARQ)

T Deneke, P Müller, P Halbfaß, A Szöllösi, M Roos… – Journal of Cardiovascular …, 2015

Background: Single-shot ablation devices for pulmonary vein isolation (PVI) in patients with

symptomatic atrial fibrillation (AF) have been increasingly used in clinical practice. Objective:

A novel mapping-system integrated irrigated multipolar circular ablation catheter (nMARQ)

 

Long-Term Effects of Ganglionated Plexi Ablation on Electrophysiological Characteristics and Neuron Remodeling in Target Atrial Tissues in a Canine Model

X Wang, M Zhang, Y Zhang, X Xie, W Wang, Z Li… – Circulation: Arrhythmia and …, 2015

Long-Term Effects of Ganglionated Plexi Ablation on Electrophysiological Characteristics and

Neuron Remodeling in Target Atrial Tissues in a Canine Model. Atrial electrophysiological

characteristics were examined before ablation, immediately and continuously after ablation.

 

… to Letter From Bisbal et al Regarding,“Repeat Left Atrial Catheter Ablation: Cardiac Magnetic Resonance Prediction of Endocardial Voltage and Gaps in Ablation

JL Harrison, C Sohns, NW Linton, R Karim, SE Williams… – Circulation: Arrhythmia and …, 2015

Tolosana JM,; Arbelo E,; de Caralt TM,; Perea RJ,; Brugada J,; Mont L. CMR-guided

approach to localize and ablate gaps in repeat AF ablation procedure. JACC Cardiovasc

Imaging . 2014;7:653–663. doi: 10.1016/j.jcmg.2014.01.014.

 

Pulmonary vein stenosis after pulmonary vein isolation using duty-cycled unipolar/bipolar radiofrequency ablation guided by intracardiac echocardiography

S Asbach, F Schluermann, L Trolese, M Langer… – Journal of Interventional …, 2015

Purpose Concerning rates of pulmonary vein (PV) stenosis were reported following PV

isolation (PVI) with a circular pulmonary vein ablation catheter (PVAC). As this may depend

on intraprocedural imaging, we evaluated the incidence of PV stenosis in patients

 

Atrioventricular Block During Slow Pathway Ablation Entirely Preventable?

H Chen, M Shehata, W Ma, J Xu, J Cao, E Cingolani… – Circulation: Arrhythmia and …, 2015

In a small percentage of cases of AVNRT, it may be necessary to ablate within the CS

with larger atrial potentials, however, ablation at the roof of the proximal CS carries

a high risk of AV nodal block during radiofrequency application.

 

Is There Still a Role for CFAE Ablation in Addition to Pulmonary Vein Isolation in Patients with Paroxysmal and Persistent Atrial Fibrillation? A Meta-Analysis of 1,415 …

R Providência, PD Lambiase, N Srinivasan, GG Babu… – Circulation: Arrhythmia and …, 2015

Is There Still a Role for CFAE Ablation in Addition to Pulmonary Vein Isolation in Patients with

Paroxysmal and Persistent Atrial Fibrillation? We aimed to assess the impact of CFAE ablation

in addition to pulmonary vein isolation (PVI) in patients undergoing ablation for AF.

 

Real-Time Contact Force Measurement A Key Parameter for Controlling Lesion Creation With Radiofrequency Energy

DC Shah, M Namdar – Circulation: Arrhythmia and Electrophysiology, 2015

Low CF values are also advisable in the vicinity of already ablated sites, where the for the

acquisition of reliable mapping information and achievement of stable ablation lesions 183 gs)

as area under curve (red hatched zone) during short duration of radiofrequency (RF) energy

 

Atrioventricular Nodal Block With Atrioventricular Nodal Reentrant Tachycardia Ablation

SJ Asirvatham, WG Stevenson – Circulation: Arrhythmia and Electrophysiology, 2015

a relatively slow stable, junctional rhythm with consistent stable retrograde atrial conduction during

radiofrequency application. of energy delivery, junctional rhythm may not be seen despite adequate

slow pathway ablation, and the operator may be inclined to ablate at more

 

[HTML] Near-infrared spectroscopy integrated catheter for characterization of myocardial tissues: preliminary demonstrations to radiofrequency ablation therapy for atrial …

RP Singh-Moon, CC Marboe, CP Hendon – Biomedical Optics Express, 2015

Abstract Effects of radiofrequency ablation (RFA) treatment of atrial fibrillation can be limited

by the ability to characterize the tissue in contact. Parameters obtained by conventional

catheters, such as impedance and temperature can be insufficient in providing

 

A Phase 2, Open-Label, Randomized Study of Pexa-Vec (JX-594) Administered by Intratumoral Injection in Patients with Unresectable Primary Hepatocellular …

CJ Breitbach, A Moon, J Burke, TH Hwang, DH Kirn – Gene Therapy of Solid Cancers, 2015

Download Protocol (725 KB). Abstract. Primary liver cancer (hepatocellular carcinoma; HCC)

in patients not eligible for surgery or transplant is currently treated by locoregional therapeutic

approaches, including trans-arterial chemoembolization and radiofrequency ablation.

 

[PDF] Feasibility and efficacy of helical tomotherapy in cirrhotic patients with unresectable hepatocellular carcinoma

CM Huang, MY Huang, JY Tang, SC Chen, LY Wang… – World Journal of Surgical …, 2015

Several other treatment modalities for patients with unresectable HCC, including percutaneous

ethanol injection (PEI), radiofrequency ablation (RFA), and transcatheter arterial

chemoembolization (TACE), seem to be more effective in smaller tumors and are contraindicated

 

The Wolf-Parkinson-White ECG Pattern-Assessing the Mortality Risk

E Posan – Journal of Insurance Medicine, 2015

32. MANAGEMENT. Radiofrequency Ablation Therapy With pacing maneuvers, the accessory

pathway properties are defined, potential tachycardias are induced, accurate mapping (localization)

of the accessory pathway is achieved and radiofrequency ablation is employed.

 

[HTML] Congenital (in growing) osteoma skull in 20-day-old neonate

PG Devi, TS Venkatachalam, YV Sharma, MP Kumar – CHRISMED Journal of …, 2015

6. 7. Virayavanich W, Singh R, O’Donnell RJ, Horvai AE, Goldsby RE, Link TM. Osteoid osteoma

of the femur in a 7-month-old infant treated with radiofrequency ablation. Skeletal Radiol

2010;39:1145-9. Back to cited text no. 7. 8. McHugh JB, Mukherji SK, Lucas DR.

 

[PDF] Simulating and Optimizing the Response of a Sine Wave Finite state Machine with Timestamp Simulation Using Simulink

M Kalpna, MA Varma – International Journal of Research, 2015

[5.] Dagmara M. Dołęga, Jerzy Barglik, (2012) “Computer modeling and simulation of

radiofrequency thermal ablation“, COMPEL – The international journal for computation and

mathematics in electrical and electronic engineering, Vol. 31 Iss: 4, pp.1087 – 1095

 

[PDF] Coexistence of permanent junctional reciprocating tachycardia with rheumatic valvular disease; a case sucessfully treated with radiofrequency ablation

M Aydın, A Yıldız, M Yüksel, Y İslamoğlu

Abstract A seventeen years old female had presented with palpitation. On the

electrocardiography (ECG), long RP, narrow QRS tachycardia, inverted P waves in leads

D2, D3 and aVF were noticed. On transthoracic echocardiography, rheumatic mitral

 

[PDF] Macrophage Inflammatory Protein Derivative ECI301

T Radiotherapy

inhibition by ECI301 was not attributable to radiation alone but also shown to other factors such

as the heat generated from high-frequency alter- nating current, namely radiofrequency ablation

(RFA; ref. 5B), significant differences were ablated by the anti- HMGB1 antibody.

 

[PDF] Regenerative Injection Treatment in the Spine: Review and Case Series with Platelet Rich Plasma. J Stem Cells Res

D Aufiero, H Vincent, S Sampson, M Bodor – Rev & Rep, 2015

back or neck pain refractory to physical therapy, trigger point injections, medial branch blocks,

or radio- frequency ablation. There is scarce evidence supporting less commonly performed

non-surgical treatments for lumbar radiculopathy including pulsed radiofrequency to the

 

[HTML] Modern medicine-morcellation

SC Olmstead

abandoned as a surgical procedure? What about noninvasive treatment options that

leave the presumed fibroid inside the body, such as uterine artery embolization,

MRI-guided focused ultrasound, and radiofrequency ablation?

 

Chronic Regional Pain Syndrome (CRPS/RSD)

 

What outcome measures are commonly used for Complex Regional Pain Syndrome clinical trials? A systematic review of the literature

S Grieve, L Jones, N Walsh, C McCabe – European Journal of Pain, 2015

Background and objective. Complex Regional Pain Syndrome (CRPS) is a chronic pain condition,

often triggered by trauma to a limb and characterized by sensory, motor, autonomic and trophic

changes within the affected limb. 2.4 Classification of CRPS clinical trials.

 

[PDF] MIRROR THERAPY: A REVIEW OF EVIDENCES

A Najiha, J Alagesan, VJ Rathod, P Paranthaman – Int J Physiother Res, 2015

Three particular conditions that have been studied the most are stroke, CRPS and phantom

limb pain. MT was used in conditions like stroke, cerebral palsy (CP), complex regional pain

syndrome (CRPS), phantom limb pain (PL) and fracture rehabilitation.

 

Physical Therapy Treatment for Patients Diagnosed with Complex Regional Pain Syndrome

J Connole – 2015

Abstract. This case study and evidence-based research analyzes the effects of physical

therapy interventions on a patient diagnosed with type 1 complex regional pain

syndrome (CRPS) to determine the most beneficial treatments.

 

Hybrid short-term freeway speed prediction methods based on periodic analysis

Y Zou, X Hua, Y Zhang, Y Wang – Canadian Journal of Civil Engineering, 2015

Page 1. Hybrid short-term freeway speed prediction methods based on periodic

analysis By Yajie Zou, Ph.D. Research associate 133B More Hall, Box 352700

Department of Civil and Environmental Engineering University of

 

[HTML] Japanese MD Develops Nutritional Protocols for Gardasil/Cervarix HPV Vaccine Injury

LC Botha – 2015

subacute sclerosing panencephalitis; CRPS: Complex regional pain syndrome; POTS:

Postural orthostatic tachycardia syndrome; Anti-phospholipid antibody syndrome;

SLE: systemic lupus erythematosus; Rheumatoid arthritis;

 

The social behavior of children adopted from Russian Federation: a controlled study

C Caprin, L Ballarin, L Benedan, A Castelli – Psicologia clinica dello sviluppo, 2015

Nonostante nella ricerca si sia utilizzata la forma estesa per genitori dello strumento

(CRPS-R:L; Conners, validazione Italiana a cura di Nobile, Alberti e Zuddas, 2007), composta

da 80 item (valori di a com- presi fra 0.57 e 0.91 per i maschi e 0.58 e 0.89 per le femmine), in

 

A Review of the Use of Stellate Ganglion Block in the Treatment of PTSD

E Lipov, EC Ritchie – Current Psychiatry Reports, 2015

14. Lipov EG, Joshi JR, et al. A unifying theory linking the prolonged efficacy of the stellate

ganglion block for the treatment of chronic regional pain syndrome (CRPS), hot flashes,

and posttraumatic stress disorder (PTSD). Med Hypotheses.

 

Addiction Recovery in Services and Policy: An International Overview

A Laudet, D Best – Textbook of Addiction Treatment: International …, 2015

model is growing in popularity nationwide: in the past decade, growing concerns about substance

use on campus and federal agencies’ focus on building a community-based continuum of care

system for youths have fueled a fivefold increase in the number of CRPs, from four

 

[HTML] Related Products

R Frank

43. Canalith Repositioning Procedures. The recommended treatment for BPPV is a canalith

repositioning procedure (CRP). There are several CRPs described in the literature; the most

studied and used in the United States was first described by Epley in 1992.

 

Central habituation and distraction alter C‐fibre‐mediated laser‐evoked potential amplitudes

P Hüllemann, YQ Shao, G Manthey, A Binder, R Baron – European Journal of Pain, 2015

Skip to Main Content. Wiley Online Library. Log in / Register. Log In E-Mail

Address Password Forgotten Password? Remember Me.

 

Nuclear Medicine Imaging of Sport Injuries of the Wrist, Hand and Fingers

M Sathekge, FE Suleman, MD Velleman, R Clauss – Nuclear Medicine and …, 2015

Abductor pollicis longus. CRPS: Chronic regional pain syndrome. 1997 ). 24.7 Complex Regional

Pain Syndrome (Reflex Sympathetic Dystrophy, Sudeck’s Dystrophy). Complex regional pain

syndrome (CRPS) is one of the most challenging chronic pain conditions of the limbs.

 

The Child with a Painful Limp

J Robb – Paediatric Orthopaedic Diagnosis, 2015

There may be symptoms of psychological distress and further specialist evaluation may

reveal an underlying cause. Complex Regional Pain Syndrome (CRPS). Children with

CRPS type 1 affecting the lower limb often limp (Wilder et al. 1992 ).

 

Complex regional pain syndrome type I. An analysis of 7 cases in children

VP Stalla, CM Olaso, VK Almada, GG Rabelino – Neurología (English Edition), 2015

Complex regional pain syndrome (CRPS) is characterised by the presence of pain accompanied

by sensory, autonomic and motor symptoms, usually preceded by a lesio.

 

Vitamin C, Extremity Trauma and Surgery

N Shibuya, MR Agarwal, DC Jupiter – 2015

987 Abstract Complex regional pain syndrome (CRPS) is a devastating condition often seen

after extrem- ity injury and surgery. Efficacy and safety of vitamin C used to prevent CRPS are

discussed. List of Abbreviations CRPS Complex regional pain syndrome Introduction

 

Psychological Factors as Outcome Predictors for Spinal Cord Stimulation

T Bendinger, N Plunkett, D Poole, D Turnbull – Neuromodulation: Technology at the …, 2015

SCS trials were offered for the following indications: failed back surgery syndrome (FBSS),

refractory radiculopathy or peripheral neuropathy, complex regional pain syndrome (CRPS),

and refractory angina (at the beginning of observed period—since 2008, this indication is not

 

[PDF] The Role of Transitional Justice and Access to Justice in Conflict Resolution and Democratic Advancement

MF Moscati – 2015

year mandate. The Community Reconciliation Processes (CRPs) of Timor-Leste were created

with the specific aim of dealing with disputes between perpetrators into their communities. The

possibility of recourse to CRPs was established by the United Nations Transitional

 

Complex Regional Pain Syndrome in Children: a Multidisciplinary Approach and Invasive Techniques for the Management of Nonresponders

MJ Rodriguez‐Lopez, M Fernandez‐Baena, A Barroso… – Pain Practice, 2015

Complex regional pain syndrome (CRPS) is multifactorial condition with complex

pathogenesis characterized by spontaneous or stimulus-induced pain that is

disproportionate to the inciting event. It is also commonly accompanied

 

Analgesic response to intravenous ketamine is linked to a circulating microRNA signature in female complex regional pain syndrome patients

SR Douglas, BB Shenoda, RA Qureshi, A Sacan… – The Journal of Pain, 2015

Although ketamine is beneficial in treating complex regional pain syndrome (CRPS), a subset

of patients respond poorly to therapy. We investigated treatment-ind. Highlights. • We studied

ketamine treatment induced miRNA alterations in blood from CRPS patients. •

 

Peptide signalling during the pollen tube journey and double fertilization

LJ Qu, L Li, Z Lan, T Dresselhaus – Journal of Experimental Botany, 2015

In general, plant peptides can be categorized into two classes: secreted peptides and

non-secreted peptides. Secreted peptides can be further divided into two major classes:

cysteine-rich peptides (CRPs) and non-CRPs (NCRPs). CRPs are significantly larger peptides.

 

[HTML] Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development

J Colling, T Tohge, R De Clercq, G Brunoud, T Vernoux… – Journal of Experimental …, 2015

Two distinct classes of secreted peptides can be distinguished in plants: small post-translationally

modified peptides such as the CLAVATA3/ENDOSPERM SURROUNDING REGION (CLE) family,

and cysteine-rich peptides (CRPs), exemplified by the EPIDERMAL

 

METHODS OF MODULATING DRUG PLASMA LEVELS USING ERYTHROHYDROXYBUPROPION

H Tabuteau – US Patent 20,150,157,582, 2015

In some embodiments, a combination of dextromethorphan and an antidepressant, such as

bupropion, may be administered to relieve complex regional pain syndrome, such as complex

regional pain syndrome type I (CRPS-I), complex regional pain syndrome type 11 (CRPS-II

 

METHODS FOR THE SAFE ADMINISTRATION OF IMIDAZOLE OR IMIDAZOLIUM COMPOUNDS

H Tabuteau – US Patent 20,150,157,564, 2015

embodiments, an osteoclast inhibitor, such as a nitrogen-containing bisphosphonate, eg

zoledronic acid, ibandronic acid or minodronic acid, may be administered to relieve complex

regional pain syndrome, such as complex regional pain syndrome type I (CRPS-I), complex

 

Fibromyalgia

 

The Use of Polysymptomatic Distress Categories in the Evaluation of Fibromyalgia (FM) and FM Severity

F Wolfe, BT Walitt, JJ Rasker, RS Katz, W Häuser – The Journal of Rheumatology, 2015

Objective The polysymptomatic distress (PSD) scale is derived from variables used in the

2010 American College of Rheumatology (ACR) fibromyalgia (FM) criteria modified for

survey and clinical research. The scale is useful in measuring the effect of PSD over the

 

Association of different levels of depressive symptoms with symptomatology, overall disease severity, and quality of life in women with fibromyalgia

A Soriano-Maldonado, K Amris, FB Ortega… – Quality of Life Research, 2015

Purpose This study examined the associations of different levels of depression with pain,

sleep quality, fatigue, functional exercise capacity, overall fibromyalgia (FM) severity, and

health-related quality of life (HRQoL) in women with FM. Methods A total of 451 women

 

Fibromyalgia: Clinical Guidelines and Treatments

E Lawson, M Wallace – 2015

 

Major Classes of Medication for Treatment of Fibromyalgia

AM Kelly, K Mauer – Fibromyalgia: Clinical Guidelines and Treatments, 2015

 

Implications of proposed fibromyalgia criteria across other functional pain syndromes

N Egloff, R von Känel, V Müller, UT Egle… – Scandinavian Journal of …, 2015

Objectives: In 2010, the American College of Rheumatology (ACR) proposed new criteria for

the diagnosis of fibromyalgia (FM) in the context of objections to components of the criteria of

1990. The new criteria consider the Widespread Pain Index (WPI) and the Symptom

 

Omar I. Halawa and David A. Edwards

DA Edwards – Fibromyalgia: Clinical Guidelines and Treatments, 2015

 

Psychophysiological Methods

RH McAllister-Williams – Encyclopedia of Psychopharmacology, 2015

potential. Tramadol reduces pain substantially in osteoarthritis and fibromyalgia

(Bennett et al. 2003). Methadone below). There is evidence of a mild degree of benefit

in low back pain, fibromyalgia, and headaches. Anticonvulsant

 

PTSD and Fibromyalgia Syndrome: Focus on Prevalence, Mechanisms, and Impact

W Häusera, J Ablinb, B Walittc – 2015

Abstract The association between fibromyalgia syndrome (FMS) and posttraumatic stress

disorder (PTSD) is of growing interest in psychosocial research. The mechanisms by which

both disorders are interconnected are not well understood. The article presents an

 

Conditioned Pain Modulation: Neurophysiological, Cognitive, And Pharmacological Aspects

RR Nir, D Yarnitsky – Topics in Pain Management, 2015

The relevance of modulatory pain mechanisms in the clinical arena is represented through

cumulative research reporting impaired pain inhibition associated with pain disorders, particularly

fibromyalgia, irritable bowel syndrome, migraine, tension-type headache

 

Ryan D. McConn and Magdalena Anitescu

RD McConn – Fibromyalgia: Clinical Guidelines and Treatments, 2015

 

[HTML] Another dimension of pain

TH Khan – Anaesth Pain & Intensive Care, 2015

Pain Manag Nurs. 2013 Dec;14(4):368-78. [PubMed] doi: 10.1016/j.pmn.2011.08.001. Menzies

V, Taylor AG, Bourguignon C. Effects of guided imagery on outcomes of pain, functional status,

and self-efficacy in persons diagnosed with fibromyalgia. J Altern Complement Med.

 

[HTML] Pattern of irritable bowel syndrome and its impact on quality of life: A tertiary hospital based study from Kolkata on newly diagnosed patients of irritable bowel …

U Sinharoy, K Sinharoy, P Mukhopadhyay… – CHRISMED Journal of …, 2015

[6],[7],[8],[9] IBS can coexist with other functional disorders, most notably fibromyalgia, chronic

fatigue syndrome 10. 11. Aaron LA, Burke MM, Buchwald D. Overlapping conditions among

patients with chronic fatigue syndrome, fibromyalgia, and temporomandibular disorder.

 

[PDF] Disability Status, Disability Type, and Training as Predictors of Job Placement

J Stahl – 2015

Deafness Hearing, Communicating Deafness Neurological Memory, Speaking TBI, Multiple

Sclerosis, Fibromyalgia Developmental Reading, Writing, Speaking Autism, Williams Syndrome

Mental Neurological Memory, Speaking TBI, Multiple Sclerosis, Fibromyalgia

 

[HTML] Pilates for Fibromyalgia

DPT Tom Lavosky, C MDT

By Gabrielle Shirer As originally seen in the Fall 2006 edition of the Pilates Coreterly

According to the National Fibromyalgia Association, Fibromyalgia Syndrome (FMS) is an

increasingly recognized chronic pain illness characterized by widespread

 

New study by guidelines author dismisses risk of chronic Lyme disease

D Cameron

In addition, these patients were not more prone to developing fibromyalgia and/or chronic fatigue,

according to two additional papers by Dr. Wormser. [1]. And previous studies report there’s a

high risk of developing fibromyalgia after having Lyme disease.

 

[HTML] Evolution of Skin Temperature after the Application of Compressive Forces on Tendon, Muscle and Myofascial Trigger Point

MF Magalhães, AV Dibai-Filho, EC de Oliveira Guirro… – PLOS ONE, 2015

of musculoskeletal, tendon or nervous injuries in the upper limb, history of fracture in the upper

limb, use of painkillers, anti-inflammatory drugs or muscle relaxants during the previous week,

presence of systemic or neuromuscular diseases, and medical diagnosis of fibromyalgia

 

[HTML] Rejuvenate With Stem Cells

R Schilling – 2015

literature. This combination (laser activated, intravenous mesenchymal injection) has

the potential for being useful for a multitude of chronic illnesses like fibromyalgia,

MS, generalized arthritis, just to mention a few. Mesenchymal

 

[PDF] Regenerative Injection Treatment in the Spine: Review and Case Series with Platelet Rich Plasma. J Stem Cells Res

D Aufiero, H Vincent, S Sampson, M Bodor – Rev & Rep, 2015

Positive results for Prolotherapy have been published for a variety of conditions including lateral

epicondylosis [21], osteoarthritis [22], sacroiliac joint pain [23], chondromalacia patellae [24],

fibromyalgia [25], chronic groin pain [26] and Osgood-Schlatter disease [27].

 

[PDF] APPROVAL SHEET

M Holman – 2015

Page 14. Effect of US and Graston on Muscle Contraction 11 plantar fasciitis,

patellofemoral disorders, fibromyalgia, scar tissue, and trigger finger. 13 The Graston

Technique allows for controlled application of friction massage to the

 

[HTML] Blueg rass Doctors of Physical Therapy, PLLC Physical Therapy Care Provider in the Louisville, Kentucky We provide EXPERT CARE for YOUR Health!

N Patient, C Forms

There are many symptoms that can lead the person with fibromyalgia syndrome (FMS)

and/or chronic myofascial pain (CMP) to your office. Research indicates that fibromyalgia

may increase the risk of cardiovascular disease (Curtis, O’Keefe Jr 2002).

Weekly Breaking Research Updates, May 22, 2015

Weekly Breaking Research Updates, May 22, 2015

Weekly Breaking Research Updates, May 22, 2015

 

Scientific breakthroughs happen every day!  In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates.  The title of each article below is a link to the full study report.  If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.

 

Ketamine

 

[HTML] Exaggerated Acute Lung Injury and Impaired Antibacterial Defenses During Staphylococcus aureus Infection in Rats with the Metabolic Syndrome

X Feng, M Maze, LG Koch, SL Britton, J Hellman – 2015

All procedures were performed under ketamine and xylazine anesthesia, and all efforts

were made to minimize suffering. Animals. The edema. At 48 h, the rats were sacrificed

under deep anesthesia provided by ketamine/xylazine.

 

Drugs that Target the Glutamate Synapse: Implications for the Glutamate Hypothesis of Schizophrenia

CA MIELNIK, A RAMSEY – Drug Discovery for Schizophrenia, 2015

In addition to the ligand bind- ing domains, NMDA receptors have modulatory sites for

zinc and spermine, and a modulatory site within the channel that binds the

non-competitive inhibitors phencyclidine (PCP), dizocilpine, and ketamine.

 

EVALUATION OF ANTHELMINTIC FISHMEAL POLYMER BAITS FOR THE CONTROL OF BAYLISASCARIS PROCYONIS IN FREE-RANGING RACCOONS ( …

TJ Smyser, SR Johnson, MD Stallard, AK McGrew… – Journal of Wildlife Diseases, 2015

lactating were released at the capture location. We anesthe- tized captured raccoons

with ketamine/xyla- zine (10 mg/kg ketamine and 2 mg/kg xylazine, intramuscularly

[Fowler 2009]). Upon induc- tion, animals were weighed

 

[PDF] Intra-ventral tegmental HIV-1 Tat1-86 attenuates nicotine-mediated locomotor sensitization and alters mesocorticolimbic ERK and CREB signaling in rats

J Zhu, NM Midde, AM Gomez, W Sun, SB Harrod – Name: Frontiers in Microbiology, 2015

session 29 (Fig 1A). 30 Briefly, rats were anesthetized using a mixture of ketamine

hydrochloride and xylazine 31 by intraperitoneal (IP) injection (7.5 mg ketamine/100

g b.wt. and 30 mg xylazine/100 g b.wt.). 32 Rats were then

 

Autonomic remodeling: How atrial fibrillation begets atrial

L Zhang, SS Po, HW PhD&, BJ Scherlag, HL PhD&… – 2015

13 Fifty-two male adult New Zealand white rabbits, weighing 2.0–2.5 kg, were 14 premedicated

with ketamine/xylazine ( 35mg/5mg/kg ),and restrained in the 15 supine position. Anesthesia

was also maintained by intra-peritoneal injection of 16 20% urethane 5 ml as needed.

 

Protein Interactions with Dopamine Receptors as Potential New Drug Targets for Treating Schizophrenia

P SUa, AHC WONG, F LIU – Drug Discovery for Schizophrenia, 2015

Page 222. Chapter 9 208 antagonist, ketamine, or PCP-induced cognitive deficits with an

inverted U-shaped dose response curve. 52 Conversely, there is less ketamine-induced

behavioral activation in D1R knockout mice than in wild-type mice.

 

Plasma arginine metabolites reflect airway dysfunction

H Grasemann, JA Scott, ML North, M Rafii, H Huang… – J Appl Physiol, 2015

On day 21, 24 h after the final aerosol challenge, mice were anesthetized (ketamine/xylazine)

for tracheal and jugular venous cannulations for ventilator-based measurement of respiratory

function and infusion of the stable L-arginine isotopomer cocktail, respectively.

 

[PDF] Histological and Histomorphometric Evaluation of Pharmacological Action of the Essential Oil of Melaleuca Alternifolia on Healing of Infected Alveolitis in Experimental …

WS Abdel-fattah, MM Dahaba, AA Ahmed… – J Interdiscipl Med Dent Sci, 2015

Materials and Methods Chemicals Tea tree oil was purchased from (SIGMA-ALDRICH

Chemie GmbH RiedstrasseUSA), vancomycin hydrochloride and ketamine were

obtained from the local pharmaceutical market. Bacterial infection

 

[PDF] Clinical Evaluation of Caudal Clonidine as an Adjuvant to Bupivacaine in Pediatric Patients Undergoing Sub Umbilical Surgeries

S Dalal – 2015

Prolongation of caudal analgesia using a single-shot technique has been achieved by addition

of various adjuvants, such as epinephrine, opioid, ketamine, and alpha 2 agonists [9]. Clonidine,

an alpha 2 agonist has extensively been used in neuraxial blocks [10- 13] and

 

The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats

E Taslidere, N Vardi, M Esrefoglu, B Ates, C Taskapan… – Human & Experimental …, 2015

kg body weight for 20 days. At the end of the experiment, rats were killed by ketamine

anesthesia. After blood samples were collected from tail vein, livers were removed

and divided into two portions. One sample was used for

 

[PDF] Assessment of the effect of ketamine on cytochrome P450 isoforms activity in rats by cocktail method

F Lin, Y He, L Zhang, M Zhang, Y Zhang, C Wen – Int J Clin Exp Med, 2015

Abstract: Cocktail method was used to evaluate the influence of ketamine on the activities of

CYP450 isoforms CYP1A2, CYP2D6, CYP3A4, CYP2C19, CYP2C9 and CYP2B6, which

were reflected by the changes of pharmacokinetic parameters of six specific probe drugs

 

Ketamine and suicidal ideation in depression: Jumping the gun?

R Rajkumar, J Fam, EYM Yeo, GS Dawe – Pharmacological Research, 2015

Abstract Depression and suicide are known to be intricately entwined but the

neurobiological basis underlying this association is yet to be understood. Ketamine is an N-

methyl D-aspartate (NMDA) receptor antagonist used for induction and maintenance of

 

Ketamine-mediated alleviation of electroconvulsive shock-induced memory impairment is associated with the regulation of neuroinflammation and soluble amyloid- …

X Zhu, P Li, X Hao, K Wei, S Min, J Luo, F Xie, J Jin – Neuroscience Letters, 2015

Abstract Electroconvulsive therapy (ECT) is an effective treatment for depression, but can

result in memory deficits. This study aimed to determine whether ketamine could alleviate

electroconvulsive shock (ECS, an analogue of ECT in animals)-induced memory

 

D-AMPHETAMINE withdrawal-induced decreases in brain-derived neurotrophic factor in sprague-dawley rats are reversed by treament with ketamine

JJL Fuller, RC Murray, KA Horner – Neuropharmacology, 2015

Abstract Withdrawal from chronic D-amphetamine (D-AMPH) can induce negative emotional

states, which may contribute to relapse and the maintenance of addiction. Diminished levels

of brain-derived neurotrophic factor (BDNF), particularly in the hippocampus has been

 

Management of acute pain in patients on treatment with opioids

J De Andres, G Fabregat-Cid, JM Asensio-Samper… – Pain Management, 2015

In fact, the use of NMDA receptor antagonists such as ketamine inhibits the development of

tolerance in test animals [15]. Inhibition of tolerance has been demonstrated in test animals with

the use of noncompetitive antagonists of NMDA receptors such as ketamine [48].

 

DrugScan

T Ha, L Abbott, J Booth, M Morrow, M Rawlins… – 2015

Emerg Med J 2014; 31: 706–13. Ketamine and Intraocular Pressure in Children This prospective

observational study sought to examine the potential increase in the intraocular pressure following

ketamine administration for paediatric procedural seda- tion.

 

Multimodal Analgesic Protocol and Postanesthesia Respiratory Depression During Phase I Recovery After Total Joint Arthroplasty.

TN Weingarten, AK Jacob, CW Njathi, GA Wilson… – Regional Anesthesia and …, 2015

Procedural sedation during block placement was with incremental dosing of intravenous midazo-

lam, fentanyl, and ketamine. Use of ketamine as a sedative for nerve blockade or analgesia was

at the discretion of the attending anesthesiologist and not part of the protocol.

 

Stem cell-based therapies for intracerebral hemorrhage in animal model: a meta-analysis

X Ma, J Qin, B Song, C Shi, R Zhang, X Liu, Y Ji, W Ji… – Neurological Sciences, 2015

CAMARADES) [10]: peer- reviewed publication; statement of control of tem- perature; random

allocation to treatment or control; blinded induction; blinded assessment of outcome; use of

anesthetic without significant intrinsic neuroprotec- tive activity (such as ketamine); use of

 

Anatomical organization of the visual dorsal ventricular ridge in the chick (Gallus Gallus): Layers and columns in the avian pallium

P Ahumada‐Galleguillos, M Fernandez, GJ Marin… – Journal of Comparative …, 2015

Deposits of biocytin in vital slices. Forty chicks (P1-P5) were deeply anesthetized with a mixture

(3:1) of 1% Ketamine and 2% Xylazine, and then decapitated. Deposits of DiI in fixed slices. Ten

chicks were deeply anesthetized using the Ketamine/Xilazine mixture and perfused

 

[PDF] Alterations in molecular pathways in the retina of early experimental glaucoma eyes

L Cao, L Wang, G Cull, A Zhou – Int J Physiol Pathophysiol Pharmacol, 2015

in one eye of each animal under ketamine and xyla- zine anesthesia. One hundred follow-

up. During each test, IOP was measured by a rebound tonometer (Tonopen XL, Reichert

Inc) under ketamine and xylazine anesthesia. The peripapillary

 

Radiofrequency Ablation (RFA)

 

… K Antagonist Oral Anticoagulants versus Vitamin K Antagonist Oral Anticoagulants in Patients Undergoing Radiofrequency Catheter Ablation of Atrial Fibrillation: A …

G Santarpia, S De Rosa, A Polimeni, S Giampà… – PloS one, 2015

BACKGROUND: Use of the non-vitamin K antagonist oral anticoagulants (NOACs) is

endorsed by current guidelines for stroke prevention in patients with atrial fibrillation (AF).

However efficacy and safety of NOACs in patients undergoing catheter ablation (RFCA) of

 

Treatment of Renal Cell Carcinomas

SN Kurukkal, SS Al-Busaidy – Urological Cancer Management, 2015

cavitational ultrasound (PCU). However, only two ablation therapies are recommended

by expert panels for the treatment of renal tumours: cryoablation and radiofrequency

ablation. hilum. 16.3.1 Radiofrequency Ablation (RFA). It is

 

[PDF] Metastatic Colorectal Cancer: Review of Diagnosis and Treatment Options

M Palaghia, CC Prelipcean, E Cotea, N Vlad… – Journal of Surgery [Jurnalul …, 2015

Liver Metastases: Addition of new, multidisciplinary techniques and therapies like systemic or

local chemotherapy, radiofrequency ablation (RFA), cryotherapy and radiotherapy improves the

rate of liver metastases resectability but currently there is no gold standard concerning

 

ть е рыв ж ть

H Takeuchi – 2015

transplantation and as a radiofrequency ablation for AF [3]. Sixty-four-slice multidetector CT

(64-MDCT) becomes an option to evaluate coronary artery stenosis. pulmonary venous stenosis

following radiofrequency ablation. Respiratory Care 2004; 49:1525-7.

 

[PDF] The natural product sulforaphane inhibits breast cancer stem cell targets in triple negative and trastuzumab-resistant breast cancers

J Burnett – 2015

metastasis (1). Substantial progress has been made with respect to the treatment of primary

tumors using surgery, chemotherapy, radiation therapy, and radiofrequency ablation. However,

the advancement of cancer to an invasive or metastatic stage is

 

[HTML] Multidisciplinary management of advanced lung neuroendocrine tumors

PL Filosso, P Ferolla, F Guerrera, E Ruffini, WD Travis… – Journal of Thoracic Disease, 2015

In the absence of hormonal control, many patients may benefit of SSA or Interferon,

associated with loco-regional therapies (liver palliative surgery, radiofrequency metastasis

ablation or trans arterial chemoembolization). Low-grade NETs.

 

[PDF] Minimally-invasive Therapy in Thyroid Practice

L Hegedüs

Ethanol ablation (PEI) • Laser ablation (ILP) • Radiofrequency ablation (RFA • Laszlo Hegedüs •

Enrico Papini (Rome, Italy) • Jung Hwan Baek (Seoul) Ford T Maserati Quatroporte Proto Spirra

Radiofrequency Ablation (RFA) Page 21. 5/13/2015 21 P < 0,0001 RFA Obs.

 

[PDF] 0915-0940 TBD 0940-1000 Coffee break/Poster viewing

M Kudo, G Abou-Alfa, O Baatarkhuu, RN Chien… – Surgery

Prof Ho Yeong Lim (Korea) 1535-1555 Novel techniques: ablation Dr Shuichiro

Shiina (Japan) Circulating biomarkers Dr Wei Tang (Japan) 1555-1615 Surgery

vs. ablation: a new balance in the era of new technologies?

 

Urological Cancer Management

SA Al-Mamari, SS Al-Busaidy

time PSM Positive surgical margins PTH-rP Parathormone-related peptide pTNM Pathological

TNM QoL Quality of life RALP Robotic assisted laparoscopic radical prostatectomy RC Radical

cystectomy RCC Renal cell carcinoma RFA Radiofrequency ablation RN Radical

 

[DOC] Deliverable 11

B Plan

Introduction. Ablatech Inc. is a novel company developing a direct current (DC) Ablation device

for the treatment of fibroadenomas and lipomas. Note: The DC Ablation generator is indicated

for use with Ablatech’s A2500 series of delivery needles, which are sold separately.

 

Radiofrequency ablation for treatment of hereditary hemorrhagic telangiectasia lesions:“How I do it”

B Rotenberg, S Noyek, CJ Chin – American Journal of Rhinology & Allergy, 2015

Introduction: Hereditary hemorrhagic telangiectasia (HHT) can cause significant epistaxis for

those that suffer from it. Traditaional surgical treatments are ablative and can cause thermal

damage. Radiofrequency (RF) energy can potentially be used to ablate HHT plaques at a

 

Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients

A Facciorusso, V Del Prete, N Crucinio, N Muscatiello… – Journal of Gastroenterology …, 2015

Methods Data on 153 patients were reviewed. The study population was classified into three

groups: 73 (47.8%) patients who received neither angiotensin converting enzyme inhibitors

nor sartans (Group 1), 49 (32%) patients treated with angiotensin converting enzyme

 

Ablative therapies: Advantages and disadvantages of radiofrequency, cryotherapy, microwave and electroporation methods, or how to choose the right method for an …

O Seror – Diagnostic and Interventional Imaging, 2015

It is important, however, to understand that each of the ablated regions created remains as possible

the functional liver parenchyma which implies to not ablate too large No touch multibipolar

radiofrequency ablation for single liver metastases: a: axial computed tomography at

 

Pulmonary Vein Stenosis After Minimally Invasive Stand‐alone Surgical Ablation of Atrial Fibrillation

E Abo‐salem, J Munjal, S Kapur – Journal of Cardiac Surgery, 2015

vein. In our case, several rounds of cryoablation alternating with radiofrequency ablation

were also applied to confirm a transmural block. An extensive ablation strategy may

have contributed to the development of stenosis. Aggressive

 

[PDF] Comparative study between conventional chemo-embolization and chemo-embolization using drug eluting beads as alternative methods for treatment of …

RS Elshahat, HA Ahmed, OI Saleh, EEA Ibrahim… – Life Science Journal, 2015

Although preliminary screening and diagnosis have allowed HCC patients to benefit from radical

resection, transplantation, or radiofrequency ablation, tumors in some patients still progress rapidly

because of local spreading or metastases, particularly in those with background

 

Treatment of hepatocellular carcinomas by thermal ablation and hepatic transarterial chemoembolization

P Chevallier, G Baudin, R Anty, A Guibal, M Chassang… – … and Interventional Imaging, 2015

It has now been shown for monopolar radiofrequency ablation that this therapy

alone is sufficient to effectively treat single HCCs < 3 cm in diameter provided that

liver micrometastases are not present. If the HCC is >3 cm in

 

The “Duality” of Idiopathic Ventricular Arrhythmias from the Left Ventricular Ostium

DJ Callans, P Santangeli – Pacing and Clinical Electrophysiology, 2015

LBBB, the other RBBB which were ablated from a single region. These patients were identified

from a series of 247 patients with idiopathic outflow tract PVCs. The methods included

electroanatomic mapping, irrigated radiofrequency ablation and site verification

 

nonsystemic treAtment of Liver metAstAses from neuroendocrine tumor

D Putzer, G Widmann, D Waitz, W Jaschke, IJ Virgolini – … Analogues: From Research …, 2015

274 NONsYsTEMIC TREATMENT Of LIVER METAsTAsEs RfA radiofrequency ablation RILD

radiation‐induced liver disease sIRT selective internal radiation therapy sPECT single photon

emission computed tomography TACE transarterial chemoembolization Us ultrasound

 

Interventional oncology for liver and lung metastases from colorectal cancer: The current state of the art

T de Baere, L Tselikas, E Pearson, S Yevitch, V Boige… – … and Interventional Imaging, 2015

tissue causes cooling through convention, which is responsible for the “heat sink effect”, and

causes difficulties in ablating tissue close to The hepatic recurrence rate in 6025 patients

undergoing surgery with or without radiofrequency ablation for malignant liver metastases from

 

One Year Incidence of Atrial Septal Defect After PV Isolation: A Comparison Between Conventional Radiofrequency and Cryoballoon Ablation

G Mugnai, J Sieira, G Ciconte, MS Hervas, G Irfan… – Pacing and Clinical …, 2015

Background: Transseptal (TS) catheterization is needed to access the left heart during

pulmonary vein isolation (PVI) procedures. In the radiofrequency (RF) ablation procedure,

left atrial access is commonly achieved with a double TS puncture; cryoballoon (CB)

 

 

Complex Regional Pain Syndrome (CRPS/RSD)

 

[PDF] Topics on estimation, prediction and bounding risk for multivariate extremes

RA Yuen – 2015

17 2.3 CRPS M-estimation for max-stable models . . . . . 20 2.4 Simulation . . . . . 141

A.1 Code for fitting max-linear models via CRPS . . . . . 142 A.2 Code for fitting a

Tawn-Molchanov max-stable model . . . . 144 BIBLIOGRAPHY . . . . .

 

[PDF] A NOVEL APPROACH TO THE MANAGEMENT OF PARSONAGE-TURNER SYNDROME

DK Garas, MD Rano Faltas, ER Viscusi

refractory CRPS, and has been found to be particularly efficacious6. • In a study

of 25 patients with refractory CRPS who underwent surgery, IV ketamine

exacerbations or spread of their CRPS at their 3 month evaluation6, 13.

 

[PDF] Preliminary Port Recovery Plan Schedule 2: Regional Coastal Environment Plan for the Canterbury Region (RCEP) Provisions-Specific Changes Sought (or wording …

L Port, P Page – policy

for by policies, rules and other methods set out in the RCEP. These changes sought are consistent

with the CRPS as set in Schedule 1. These changes sought are consistent with the CRPS as set

out in Schedule 1. Amendments sought to Action 7 are Insert a new policy:

 

Organisational Complaint Management

S Garding, A Bruns – Complaint Management and Channel Choice, 2015

2013). Garnefeld et al. (2013) even recommend companies to consider “building CRPs

into social media campaigns to take advantage 6 1 Organisational Complaint

Management Page 7. of the increasing social commerce opportunities”.

 

[PDF] Reverse total shoulder arthroplasty for complex proximal humeral fractures in the elderly: How to improve outcomes and avoid complications

RPDM UCT, F Ortho, UCT MMed Orth, BVM Zim, F Orth… – pain

139 (90–180) – 27 (0–45) 1 (VAS) 10% 1 patient with CRPS, DVT, and GT resorption, 1 patient

with GT malunion, 1 patient with Grade 1 notching ASES 78 T a b le I: R esu lts o RTSA 9

133(±20) 41 (±19) 1 (±1) 1/9 CRPS (recovered) ASES 80 (±11) T a b le II: R esu lts fo r stu

 

[PDF] Syringomyelia & Spinal Cord Stimulation

RB Pitkanen, DL James

found to be successfully used in the treatment of several neuropathic pain syndromes

such as radiculopathy, failed back surgery syndrome, CRPS, post-herpetic neuralgia,

as well as to a lesser extent for chronic migraine, refractory

 

[PDF] Neuropsychology of Chronic Pain

EM Desensitization

For example, com- plex regional pain syndrome (CRPS) is caused by a disturbance of the

sympathetic nervous system— the network of nerves located along the spinal cord that controls

bodily functions such as the opening and closing of blood vessels and sweat glands.

 

Stefan Garding Andrea Bruns

SBIN BUSINESS

2013). Garnefeld et al. (2013) even recommend companies to consider “building CRPs

into social media campaigns to take advantage 6 1 Organisational Complaint Management

Page 19. of the increasing social commerce opportunities”.

 

” What I really needed was the truth”. Exploring the information needs of people with Complex Regional Pain Syndrome

S Grieve, C McCabe, J Adams – Musculoskeletal Care, 2015

Download (52Kb) | Request a copy: Description/Abstract. Background United Kingdom

guidelines indicate individuals with Complex Regional Pain Syndrome (CRPS) require

information and education to support self management.

 

Reprogramming of in situ spinal cord stimulator for covering newly developed postthoracotomy pain

NN Knezevic, MV Rana, P Czarnocki… – Journal of Clinical …, 2015

Postthoracotomy pain; Spinal cord stimulation. 1. Introduction. Spinal cord stimulation has become

increasingly successful in the treatment of pain syndromes, especially neuropathic pain, ranging

from failed back surgery syndrome to complex regional pain syndrome (CRPS).

 

Late Amputation May Not Reduce Complications or Improve Mental Health in Combat-Related, Lower Extremity Limb Salvage Patients

CA Krueger, JC Rivera, DJ Tennent, AJ Sheean… – Injury, 2015

Table 2. Documented reasons of why the limb salvage patients wanted a late amputation. CRPS:

Chronic Regional Pain Syndrome. Reasons for Desired Late Amputation, (n, %), Lack of joint

motion, 6, 13%. Lack of strength, 4, 9%. Skin coverage or flap failure, 2, 5%. CRPS, 1, 2%

 

Community-Based Review of Research Across Diverse Community Contexts: Key Characteristics, Critical Issues, and Future Directions

N Shore, A Ford, E Wat, M Brayboy, ML Isaacs, A Park… – American Journal of Public …, 2015

These community-based research review processes (CRPs) can provide individual and

community-level ethics protections, enhance the cul- tural relevance of study de- signs and

competence of re- searchers, build community and academic research capac- ity, and shape

 

Bayesian Model Averaging with Stratified Sampling for Probabilistic Quantitative Precipitation Forecasting in Northern China during Summer 2010

J Zhu, F Kong, L Ran, H Lei – Monthly Weather Review, 2015

Page 1. Monthly Weather Review EARLY ONLINE RELEASE This is a preliminary PDF of

the author-produced manuscript that has been peer-reviewed and accepted for publication.

Since it is being posted so soon after acceptance, it has not yet been

 

COMPOSITIONS AND METHODS OF USING THREOHYDROXYBUPROPION FOR THERAPEUTIC PURPOSES

H Tabuteau – US Patent 20,150,133,485, 2015

In some embodiments, a combination of dextromethorphan and an antidepressant, such as

bupropion, may be administered to relieve complex regional pain syndrome, such as complex

regional pain syndrome type I (CRPS-I), complex regional pain syndrome type II (CRPS-II

 

BUPROPION AS A MODULATOR OF DRUG ACTIVITY

H Tabuteau – US Patent 20,150,133,486, 2015

In some embodiments, a combination of dextromethorphan and an antidepressant, such as

bupropion, may be administered to relieve complex regional pain syndrome, such as complex

regional pain syndrome type I (CRPS-I), complex regional pain syndrome type II (CRPS-II

 

Osteoclast Inhibitors for Knee Conditions

H Tabuteau, G Jones – US Patent 20,150,133,403, 2015

embodiments, an osteoclast inhibitor, such as a nitrogen-containing bisphosphonate, eg

zoledronic acid, ibandronic acid or minodronic acid, may be administered to relieve complex

regional pain syndrome, such as complex regional pain syndrome type I (CRPS-I), complex

 

Neuroimaging-based biomarker discovery and validation.

CW Woo, TD Wager, CW Woo – PAIN, 2015

Neuroimage 2008;40(2):788-795. [11] Geha PY, Baliki MN, Harden RN, Bauer WR, Parrish

TB, Apkarian AV. The brain in chronic CRPS pain: abnormal gray-white matter interactions

in emotional and autonomic regions. Neuron 2008;60(4):570-581.

 

[PDF] IASP Interprofessional Pain Curriculum Outline

N Kariuki, J Miró, L Niemi-Murola, G Ochoa…

Primary Lesion Peripheral • degenerative disc disease with radiculopathy in neck and low back •

peripheral neuropathies (diabetes, cancer, alcohol, HIV) • post herpetic neuralgia • acute disc

herniation with radiculopathy • complex regional pain syndrome II (CRPS II) (causalgia

 

Fibromyalgia

 

Inflammatory Allied Conditions

MA Oliveira, A Ciechomska – Musculoskeletal Ultrasonography in Rheumatic …, 2015

biopsies. Whereas in fibromyalgia, there are conflicting data about the utility of US,

and if used, it is mainly to exclude other causes of pain. XXXIX. Sonographic assessment

of hip in fibromyalgia patients. Clin Exp Rheumatol 30: pp.

 

Childhood adversity and illness progression in bipolar disorder

J Bücker, M Kauer-Sant’Anna, LN Yatham – Neuroprogression and Staging in Bipolar …, 2015

BD patients with a history of childhood adversity also seem to report comorbidity with numerous

medical conditions, including allergies, arthritis, asthma, chronic fatigue syndrome, chronic

menstrual irregularities, fibromyalgia, head injury, hypotension, irrit- able bowel syndrome

 

The Use of Motivational Interviewing in Physical Therapy Education and Practice: Empowering Patients Through Effective Self-Management

RM Pignataro, PT James Huddleston – Journal of Physical Therapy Education, 2015

been successfully employed in promoting adherence to a walking program in patients receiving

chemotherapy for breast cancer,42 in improving health promotion behaviors among people with

coronary risk factors,42 and in promoting exercise in patients with fibromyalgia.39 In

 

[PDF] Temporomandibular Joint Dysfunction

J Poduval – JMR, 2015

J Craniomandib Disord 1992, 6:301-355. 4. Truta MP, Santucci ET, Donlon WC. Head

and Neck fibromyalgia and temporomandibular arthralgia. In: Jacobson AL, Donlon WC,

(Eds). Headache and Facial Pain. New York: Raven, 1990:141.

 

From the Desk of Dr. Karl ROS Johnson, DC…..

ROS Karl

Intentional musings of a unique Shelby Township Michigan Chiropractic Physician dedicated

to helping people find solutions to improving their health by rooting out causes to chronic

conditions such as fibromyalgia, thyroid disorder symptoms, balance disorders, migraines

 

Ankylosing Spondylitis

M Backhaus, Y El Miedany – Musculoskeletal Ultrasonography in Rheumatic …, 2015

Beside spondyloarthritis patients, enthesitis have been reported among athletes

as a consequence of traumatic injuries. Distinguishing fibromyalgia tender points

from enthesitis is another important challenge to be considered.

 

[HTML] Development of a Learning-Oriented Computer Assisted Instruction Designed to Improve Skills in the Clinical Assessment of the Nutritional Status: A Pilot Evaluation

LG de Diego, M Cuervo, JA Martínez – 2015

Advertisement.

 

[PDF] P1. Community-Clinical Linkages in the WISEWOMAN Program

K Ahmed, I Vaid, D May, D Manheim – JOURNAL OF WOMEN’S HEALTH, 2015

this study. Of the women patients, 361 reported a history of hysterectomy. A

comparison group consisted of 361 patients with a primary diagnosis of headache

or fibromyalgia without history of hysterectomy. Patients completed

 

[HTML] The Hot Sauce: Peppers and Fat Loss

VR Prisk

Aside from deterrence of muggers and bets between friends, there are many therapeutic

applications of capsaicin. Capsaicin creams, which desensitize nerves over time, are used

to treat neuropathy, shingles, psoriasis, arthritis pain and fibromyalgia.

 

[PDF] TEMPORALITY AND INFORMATION WORK IN BONE MARROW TRANSPLANT

AG Büyüktür – 2015

al., 2010; Hubbard et al., 2010), motor neuron disease (eg Locock et al., 2009), chronic fatigue

syndrome and fibromyalgia (eg Asbring, 2001), HIV infection (eg Anderson et al., 2010; Wilson,

2007), and multiple sclerosis (eg Green et al., 2007), among others.

 

34 Fibromyalgia, Chronic Fatigue, Functional Disorders, and Vaccination: Where Do We Stand?

JN Ablin, D Buskila – Vaccines and Autoimmunity, 2015

 

Gender and psychosocial context as determinants of fibromyalgia symptoms (fibromyalgia research criteria) in young adults from the general population

S Lourenço, L Costa, AM Rodrigues, F Carnide… – Rheumatology, 2015

Objective. To quantify the prevalence of FM (FM research criteria), to describe its

components—symptom severity score (SSS) and widespread pain index (WPI)—and to

identify biopsychosocial predictors of the severity of SSS as well as WPI using a

 

Fibromyalgia and the Risk of a Subsequent Motor Vehicle Crash

DA Redelmeier, JD Zung, D Thiruchelvam… – The Journal of …, 2015

Objective Motor vehicle crashes are a widespread contributor to mortality and morbidity,

sometimes related to medically unfit motorists. We tested whether patients diagnosed with

fibromyalgia (FM) have an increased risk of a subsequent serious motor vehicle crash.

 

Association of antithyroid peroxidase antibody with fibromyalgia in rheumatoid arthritis

J Ahmad, H Blumen, CE Tagoe – Rheumatology International, 2015

Abstract To investigate how autoimmune thyroiditis (ATD) affects the clinical presentation of

established rheumatoid arthritis (RA) with particular reference to fibromyalgia and chronic

widespread pain (CWP). A cohort of 204 patients with RA for whom the presence or

 

Association between fibromyalgia and thyroid autoimmunity

N Shirzad, S Movassaghi, H Karmostaji, F Esfahanian… – 2015

Fibromyalgia is a disorder characterised by fatigue, generalised body pain and cognitive

symptoms, and the aetiology has not been clearly described. Because similar symptoms are

frequently found in Hashimoto’s thyroiditis and there is not an optimal response to the

 

COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESTLESS LEG SYNDROME AND FIBROMYALGIA

M Kandula – US Patent 20,150,133,408, 2015

Abstract: The invention relates to the compounds of formula I or its pharmaceutical

acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates

thereof. The pharmaceutical compositions comprising an effective amount of compounds

 

[PDF] REVISTA BRASILEIRA DE REUMATOLOGIA

SB de Lorena, MCC de Lima, A Ranzolin, ÂLBP Duarte – rev bras reumatol, 2015

Review article Effects of muscle stretching exercises in the treatment of fibromyalgia: a systematic

review articleinfo Article history: Received 16 March 2014 Accepted 17 August 2014 Available

online 6 January 2015 Keywords: Fibromyalgia Stretching Physiotherapy abstract

 

36 Infections, Vaccinations, and Chronic Fatigue Syndrome

H Mahagna, N Mahroum, H Amital – Vaccines and Autoimmunity, 2015

 

COMPOSITIONS AND METHODS FOR INDUCING MYOBLAST DIFFERENTIATION AND MYOTUBE FORMATION

MP Czech, M Wang – US Patent 20,150,133,520, 2015

12. The method of claim 11, wherein the muscle disorder is selected from the group consisting

of: muscle atrophy, muscle weakness, myopathy, chronic fatigue syndrome, fibromyalgia, muscular

dystrophy, fatigue fibromyalgia, spinal muscle atrophy, distal muscular dystrophy

 

27 Aluminum Particle Biopersistence, Systemic Transport, and Long-Term Safety: Macrophagic Myofasciitis and Beyond

RK Gherardi, J Cadusseau, FJ Authier – Vaccines and Autoimmunity, 2015

First randomized clinical trial shows efficacy of intravenous ketamine for treating Posttraumatic Stress Disorder

First randomized clinical trial shows efficacy of intravenous ketamine for treating Posttraumatic Stress Disorder

First randomized clinical trial shows efficacy of intravenous ketamine for treating Posttraumatic Stress Disorder

A team of researchers put intravenous (IV) ketamine therapy to the test in forty-one patients with chronic Posttraumatic Stress Disorder (PTSD).  Their results were published in the Journal of the American Medical Association Psychiatry (JAMA Psychiatry).  This was the first randomized clinical study of its kind, pinning IV ketamine against an active placebo, IV midazolam.   The primary outcome measure of the study was change in PTSD symptom severity.  To this end, ketamine was associated with “significant and rapid reduction in PTSD symptom severity, compared with midazolam”.  Interestingly, ketamine was also associated with a reduction in comorbid depressive symptoms and an improvement in overall clinical presentation, a novel finding in these difficult to treat patients.

Further, the authors found intravenous ketamine in this cohort of patients to be well tolerated without clinically significant persistent dissociative symptoms.  This study provides the first evidence for the rapid treatment of PTSD using intravenous ketamine—a finding that will hopefully support novel approaches to the pharmacologic treatment of patients with this disabling condition.

Dr. Ashraf Hanna, M.D. and his team of expert clinicians at the Florida Spine Institute utilize IV ketamine infusion therapy to treat a myriad of diseases.  To find out if IV ketamine might be right for you, please make an appointment with Dr. Hanna.

Full Article: Feder A, Parides MK, Murrough JW, et al. Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder: A Randomized Clinical TrialJAMA Psychiatry. 2014;71(6):681-688. doi:10.1001/jamapsychiatry.2014.62.

Weekly Breaking Research Updates

Weekly Breaking Research Updates

Scientific breakthroughs happen every day!  In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates.  The title of each article below is a link to the full study report.  If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.

Ketamine

[PDF] Transscalene Brachial Plexu Approach for Brachial Plexus

SR Totawar – Age, 2015

tchy action of the block, the block was converted to general anesthesia. If in case surg e effect

of the block wore off, rescue analgesia with intravenous ketamine given. In the circumstance

of nesthesia. If in case surgery was unduly us ketamine given.

 

Giuseppe D’Agostino1, 2*, Claudia Cristiano1, 2, 3, David J. Lyons2, Rita Citraro4, Emilio Russo4

C Avagliano, R Russo, GM Raso, R Meli, G De Sarro… – 2015

pharmacological PPAR-α agonist treatment in mice improves behavior in a pharmacological

model of ketamine-induced behavioral dysinhibition and repetitive behavior in BTBR T+ tf/J mice.

Keywords: lipids; nuclear receptor; ketamine; memory; neurodevelopmental disorders;

 

[PDF] Efficacy conventional intersc approach Vs novel transscal of brachial plexus block

SR Totawar – 2015

In the circumstance of inad anaesthesia. If in case surgery was undu intravenous

ketamine given. If in case surgery was unduly prolonged and the effect of the block

wore off, rescue analgesia with intravenous ketamine given.

 

Radiofrequency Ablation of the Pancreas: Protective Effect of Local Cooling Techniques

A Geranios, E Pikoulis, A Papalois, M Kontos… – The American Surgeon, 2015

1). Surgical Procedure The animals were anesthetized with ketamine (15–20 mg/kg) and

midazolam (0.5 mg/kg) in- tramuscularly and then intubated. The maintenance of anesthesia

was achieved by thiopental (3.5 mg/kg/hr) and fentanyl (15 mg/kg/hr).

 

[HTML] Original Study Enhancement of Acute Tendon Repair Using Chitosan Matrix

E Melamed, BG Beutel, D Robinson – Am J Orthop, 2015

Tikva, Israel. The rats were anesthetized with ketamine 90 mg/kg and xylazine 10

mg/kg, both administered intramuscularly, and anesthesia was prolonged as needed

with 2% isoflurane, administered by nose cone. The skin

 

[PDF] Cyclosporine A Reduces Glial Scarring and Facilitates Functional Recovery Following Transient Focal Ischemia

HCS Abeysinghe, L Bokhari, GJ Dusting, C Roulston – J Neurol Neurophysiol, 2015

food and water. Rats were anaesthetized using a mixture of Ketamine/Xylazine

(75 mg/kg: 10 mg/kg respectively ip) and maintained throughout surgery by inhalation

of isoflurane (95% oxygen and 5% isoflurane). A 23-gauge

 

Antiseizure medications

S Sanders – Seizures in Dogs and Cats

felbamate (FBM); ketamine (KET); lacosamide (LCM). Summary. The uncommon drugs include

felbamate (FBM), ketamine (KET), lacosamide (LCM), and propofol (PRO). Some of the rarely

used drugs are carbamazepine, ethosuximide, and valproic acid. Get PDF (344K).

 

Chronic neurokinin-1 receptor antagonism fails to ameliorate clinical signs, airway hyper-responsiveness or airway eosinophilia in an experimental model of feline …

M Grobman, A Graham, H Outi, JR Dodam, CR Reinero – Journal of Feline Medicine …, 2015

23 Briefly, ketamine (30 mg IV) was used as a premedicant, propofol was used for induction

(6 mg/kg) and maintenance (0.3 mg/kg/min), and cisatracurium (0.1 mg/kg IV of with additional

doses of 0.01–0.02mg/kg titrated to effect) was administered for neuromuscular blockade.

 

[PDF] Evaluation of Anti-inflammatory and Analgesic Activities of Cymbopogon citratus in vivo-Polyphenols Contribution

R Garcia, JP Ferreira, G Costa, T Santos, F Branco… – Research Journal of …, 2015

Ketamine (Ketalar, 7.7 mg kgG )1 was purchased from Parke-Davis, Pfizer (Seixal,

Portugal) Chlorpromazine (Largatil, 2.3 mg kgG )1 was purchased from

Rhône-Poulenc Rores, Laboratório Vitória SA (Amadora, Portugal).

 

Acute neurokinin-1 receptor antagonism fails to dampen airflow limitation or airway eosinophilia in an experimental model of feline asthma

M Grobman, S Krumme, H Outi, JR Dodam… – Journal of Feline Medicine …, 2015

19 Briefly, ketamine (30 mg IV) was used as a premedicant, propofol was used for induction

(6 mg/kg) and maintenance (0.3 mg/kg/min), and cisatracurium (0.1mg/kg IV, with additional doses

of 0.01–0.02 mg/kg titrated to effect) was administered for neuromuscular blockade.

 

Radiofrequency Ablation (RFA)

 

Radiofrequency Ablation of the Pancreas: Protective Effect of Local Cooling Techniques

A Geranios, E Pikoulis, A Papalois, M Kontos… – The American Surgeon, 2015

Pancreatic carcinoma is one of the commonest malignant diseases today and the majority of

patients are suitable for palliative treatment only. Radiofrequency ablation (RFA) has been

used extensively for the treatment of solid organ tumors but little is known on the efficacy

 

Effects of renal denervation from the intima and the adventitia of renal arteries on renal sympathetic nerve activity in dogs: a comparative study

M Bai, C Yang, C Gao, X Wang, H Liu, Y Zhang, J Liu… – Cardiology, 2015

A cardiac radiofrequency ablation catheter was then applied to ablate the adventitia from the

outside, also of 8 W or less and lasting up to 2 min each to obtain up to six ablations separated

both longitudinally and rotationally, which was the same as the ablation of renal

 

[PDF] Laryngopharyngeal Reflux: a Syndrome that Mimics Asthma

M Merchant – Proceedings of UCLA Healthcare, 2015

Surgical options include minimally invasive procedures such as radiofrequency ablation of the

lower esophageal sphincter as well as endoscopic Nissen Fundoplication, a procedure where

the surgeon wraps the stomach around the distal esophagus to create a tight valve.

 

Helical DeNervation Ablation Catheter Apparatus

J Mogul – US Patent 20,150,126,992, 2015

sympathetic nerves which run through the adventitia of the renal arteries using radiofrequency

(RF) energy The catheter’s RF-ablation electrode(s) will then be deployed by movement of the

slider the endoluminal, or inner arterial, surface of the artery in order to ablate the renal

 

Method and Apparatus for Tissue Ablation

VK Sharma, H Jabs – US Patent 20,150,126,990, 2015

can use one or more sources of infrared, electromagnetic, acoustic or radiofrequency energy

to anal canal; engaging the targeted hemorrhoid by suctioning the hemorrhoid into the ablation

device; and, delivering the ablative agent to the hemorrhoid to ablate the hemorrhoid

 

[PDF] N. Ayez1, EP van der Stok1, DJ Grünhagen1, J. Rothbarth1, E. van Meerten2, AM Eggermont3, C. 5 Verhoef1 6 7

DJ Grünhagen – 2015

Local treatment was performed in 122 170 patients (47%) (surgery, radiofrequency ablation,

stereotactic radiotherapy), 112 patients (43%) had 171 palliative chemotherapy and 29 patients

(11%) received neither chemotherapy nor local treatment. 172

 

METHOD AND SYSTEM FOR SKIN TREATMENT

M Jurna, JA Palero, MR Horton – US Patent 20,150,126,913, 2015

The modifier is configured to decrease the electrical impedance for the radiofrequency energy,

in particular exploited concurrent with and/or directly subsequent to the burning and/or ablation

step and as the aforementioned 70° C., and/or the laser is used to ablate skin portions

 

Operative Techniques in Thoracic and Esophageal Surgery

M Hawn – 2015

 

Apparatus and Methods Related to Constrained Deployment of Cryogenic Balloons for Limited Cryogenic Abiation of Vessel Walls

B Kelly, J Kelly, G Kelly, B Mullins – US Patent 20,150,126,986, 2015

As compared to ablation lesions formed via radiofrequency energy, cryotherapy typically utilizes

much less power vessel wall and thus results in a smaller nominal treatment area/ablation pattern

than In another embodiment (not shown), if it is desired to ablate more than half of

 

[PDF] Long-term efficacy of radiofrequency ablation compared to surgical resection for the treatment of small hepatocellular carcinoma

X Bu, Z Ge, J Ma, S Guo, Y Wang, J Liu

Xiangyang Bu1,2*, Zhong Ge3*, Jian Ma4, Shanyuan Guo5, Yi Wang3, Jun Liu6 1Department

of Hepatobiliary Surgery, Qilu Hospital of Shandong University, Jinan 250021, China; 2Department

of Hepatobiliary Surgery, Qingdao Municipal Hospital, Qingdao 266011, China;

 

Complex Regional Pain Syndrome (CRPS/RSD)

 

Evolving Chinese Restaurant Processes for Modeling Evolutionary Traces in Temporal Data

P Wang, C Zhou, P Zhang, W Feng, L Guo, B Fang – Advances in Knowledge …, 2015

To model cluster branching over time, ECRP lets each cluster in current epoch form a Chinese

Restaurant Process (CRP) and uses the combination of cluster-specific CRPs as the prior for

clusters in the next epoch. where ωt−1,k and ωt,O are the weights of CRPs.

 

Practical Problems With Clinical Guidelines for Breast Cancer Prevention Based on Remaining Lifetime Risk

AS Quante, AS Whittemore, T Shriver, JL Hopper… – Journal of the National …, 2015

To evaluate discrimination, we computed the overall AUC and we plotted case risk

percentiles (CRPs, also called standardized placement values) (21) for the subjects who

developed breast cancer within 10 years of recruitment (case patients).

 

PIPERIDINE COMPOUND AND ITS USE IN PEST CONTROL

S Arimori – US Patent 20,150,126,516, 2015

A01N43/58. Related US Applications: 20040209906, Composition comprising

ketanserin AND AN ALKANOYL L-CARNITINE FOR THE TREATMENT OF CRPS,

October, 2004, Cavazza et al. 20070249732, USE OF CERTAIN

 

[PDF] News from the Patient Liaison Committee: The brave new world ‘How are pain services evolving–the impact on patients?’

A Chuter – Reltebon® Oxycodone Prolonged-release Tablets, 2015

Page 16. March 2015 Vol 13 No 1 l Pain News 13 Pain News 2015, Vol 13 (1)

13–14 © The British Pain Society 2015 News After months of planning by Geraldine

Granath, Colin Preece, Liz Killick, Austin Leach and Antony Chuter

 

SYSTEMS AND METHODS FOR COMPOUND MOTOR ACTION POTENTIAL MONITORING WITH NEUROMODULATION OF THE PELVIS AND OTHER BODY …

KD Benson, VR Lucente, JR Miklos – US Patent 20,150,126,894, 2015

Neuromodulation has also been used safely and effectively to help relieve chronic back pain,

pain from cancer and other nerve injuries, and pain from Complex Regional Pain Syndrome

(CRPS) and Reflex Sympathetic Dystrophy (RSD), greatly improving the quality of life for

 

[PDF] EXPLORATION OF FACTORS ASSOCIATED WITH PATIENT ADHERENCE IN UPPER EXTREMITY REHABILITATION: A MIXED-METHODS EMBEDDED DESIGN

EV Smith-Forbes – 2015

Multi-joint Fracture Multiple 0.0% 0.0% 0.0% 2.0% CRPS 0.0% 0.0% 0.0% 1.6% Nerve Injury

0.0% 0.0% 0.0% 1.2% MCID= minimal clinical important difference, DRUJ= distal radio-ulnar

joint, CRPS = complex regional pain syndrome, ROC = receiver operator characteristics

 

[PDF] Temperature Dependent Dielectric Model at 1.4 GHz for an Agricultural Soil Thawed and Frozen

VL Mironov, AY Karavaysky

0.513 The results of validation measurements for the soil CRPs are displayed in

Fig. range. To obtain the error of the developed model, we correlated the predicted

CRPs with the ones especially measured for validation. In Fig.

 

[PDF] A Bayesian A Bayesian Beta Markov Random Beta Markov Random Field Calibration of the Term structure of implied risk neutral densities densities

R Casarin, FR Casarin, F Leisen, GMGMG Molina…

Page 1. A Bayesian A Bayesian Beta Markov Random Beta Markov Random Field Calibration

of the Term structure of implied risk neutral densities densities Roberto Casarin, Fabrizio Roberto

Casarin, Fabrizio Leisen, German Molina German Molina German Molina,

 

 

Fibromyalgia

 

[PDF] Heart rate turbulence analysis in female patients with fibromyalgia

O Solak, H ToktasIV – 2015

OBJECTIVE: Fibromyalgia is characterized by diffuse musculoskeletal pain and discomfort.

There are several reports regarding autonomic nervous system dysfunction in patients with

fibromyalgia. Heart rate turbulence is expressed as ventriculophasic sinus arrhythmia and

 

[HTML] FIBROMYALGIA: CURABLE

ME Platt – Alternative Medicine, 2015

Abstract From a survival standpoint, the body always wants to make sure the brain has

enough fuel.[…] any time the body detects a low amount of fuel in the brain, it releases

adrenaline to raise sugar levels.[…] use of these methods often leads to a cure for

 

[PDF] Association of Impaired Sleep Quality in Patients With Burning Mouth Syndrome: A Case-Control Study

F Arbabi-Kalati, NM Bakhshani, B Tahmtan… – 2015

deprivation. Sleep deprivation can also lead to mood changes, insomnia and fatigue,

affecting pain sensation (2). Patients with known fibromyalgia have a lower noc- turnal

sleep quality compared to controls and have more insomnia

 

Dizziness, Lightheadedness, and Syncope in a Patient with Type 2 Diabetes

S Paturi, JL Gilden, F FCP – Diabetes Case Studies: Real Problems, Practical …, 2015

 

Vagally mediated heart rate variability in headache patients—a systematic review and meta-analysis

J Koenig, DWP Williams, AH Kemp, JF Thayer – Cephalalgia, 2015

capabilities (21). Lower vmHRV is reported in a variety of chronic painful conditions,

such as chronic neck pain (22), chronic pelvic pain (23), complex regional pain (24),

fibromyalgia (25,26) and irritable bowel syndrome (27). In

 

Novel Therapeutic Uses of Mu-Opiate Receptor Peptides

TE Maione – US Patent 20,150,126,455, 2015

pain. 16. The method, according to claim 1, used to reduce chronic noncancer pain

selected from pain associated with arthritis, neuropathy, low back pain, osteoarthritis,

fibromyalgia, headache, and diabetic neuropathy. 17.

 

Brain-gut axis: gastroenterology-IBS

J Wright – The Specialist Forum, 2015

to controls. Interestingly, this hypoalgesia was even greater in patients with concomitant

fibromyalgia, suggesting a commonality between these two symptom-driven diagnoses.

Anticipatory factors may also play a part. In experiments

 

[PDF] A Pilot Study Measuring Outcomes of Managing Fascial Health for Individuals With Fibromyalgia

KB Segarra

Abstract This article examines the outcomes of managing fascial health for persons

diagnosed with fibromyalgia based on the protocol developed by the author, Dr. Kirstie

Bender Segarra, and implemented in a pilot study of five clients. The protocol was

 

[PDF] The Somatosensory Amplification in Vitiligo and Chronic Urticaria Patients: A Controlled Study

M Sukan, F Maner – J Neurol Disord, 2015

Amplification may be a pathogenic mechanism in certain specific amplification

disorders such as fibromyalgia and irritable bowel syndrome [9]. Some individuals

are generally more sensitive to bodily sensation than others.

 

Psychotherapy and mental health as a psychological science discipline

HU Wittchen, S Härtling, J Hoyer – Verhaltenstherapie, 2015

which behavioural factors play a significant role in the initiation, maintenance and rehabilitation,

such as cancer (eg [Fors et al., 2011]), cardiovascular disease (eg [Gulliksson et al., 2011]),

metabolic disease and obesity (eg [Grilo et al., 2012]), and fibromyalgia [Kashikar-Zuck et

New discoveries for the treatment of pain

New discoveries for the treatment of pain

Weekly Breaking Research Updates

 

Scientific breakthroughs happen every day!  In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates.  The title of each article below is a link to the full study report.  If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.

 

Ketamine

 

Ketamine-A Narrative Review of Its Uses in Medicine.

BM Radvansky, S Puri, AN Sifonios, JD Eloy, V Le – American Journal of Therapeutics, 2015

One of the most fascinating drugs in the anesthesiologist’s armament is ketamine, an N-

methyl-D-aspartate receptor antagonist with a myriad of uses. The drug is a dissociative

anesthetic and has been used more often as an analgesic in numerous hospital units,

 

Acute administration of ketamine inhibited stress induced pro-inflammatory cytokines in hippocampus of rats

G Unal, G Terzioglu, C Sahin, GY Demirel, F Aricioglu – Bulletin of Clinical …, 2015

Objective: Major depression is a complex and devastating disease which one-third of

patients still do not respond to current treatments. It has been demonstrated that there is a

correlation between high levels of plasma cytokines such as IL-1β, IL-6, IL-18 and TNF-α

 

The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology.

GS Aylan, N Sarper, U Demirsoy, E Zengin, E Çakmak – Turkish journal of …, 2015

OBJECTIVE: The aim of this study is to investigate the efficacy and safety of sedoanalgesia

performed outside the operating room by pediatricians trained in advanced airway

management and life support. MATERIALS AND METHODS: Midazolam and ketamine …

 

[HTML] Alpha-lipoic acid alone and combined with clozapine reverses schizophrenia-like symptoms induced by ketamine in mice: Participation of antioxidant, nitrergic and …

GS Vasconcelos, NC Ximenes, CNS de Sousa… – Schizophrenia Research, 2015

Abstract Oxidative stress has important implications in schizophrenia. Alpha-lipoic acid

(ALA) is a natural antioxidant synthesized in human tissues with clinical uses. We studied

the effect of ALA or clozapine (CLZ) alone or in combination in the reversal of

 

Low Dose Ketamine Infusion For Managing Acute Pain

M Yetim, S Tekindur, Y Emrah Eyi – The American Journal of Emergency Medicine, 2015

Dear Editor, We read with great interest the article “Short (low-dose) ketamine infusion for

managing acute pain in the ED: case-report series” written by Goltser et al (1). We believe

that this original study provides a new and insightful approach to pain management in

 

[PDF] Symptomatic remission and hippocampus volume in schizophrenia

PT Chang, JF Lirng, YH Chou – Bulletin of Clinical Psychopharmacology, 2015

1):S146-S7 [Abstract:0577] Neuroimaging in psychiatry Alterations in resting state electrocortical

network oscillations, schizophrenia-like symptoms and their relationships induced with the

administration of the NMDA receptor antagonist ketamine in human volunteers

 

G535 (P) The development and implementation of a policy promoting parental (patient) involvement in escalation of clinical care

MA Webster, C Haines, J Fraser – Archives of Disease in Childhood, 2015

www.midstaffspublicinquiry.com/report (accessed 28 Nov 2014) G536(P) THE CHALLENGES

OF SETTING UP A KETAMINE SEDATION SERVICE IN THE PAEDIATRIC ED – LEARNING

LESSONS AND EFFECTING CHANGE 1E Dewhirst, 1C Whitehouse, 2T Waterfield.

 

[PDF] Eyes tell the psychopathology: preliminary findings

H Balibey, C Basoglu, A Ates, A Algul, R Tutuncu… – Bulletin of Clinical …, 2015

On the other hand, the behavioral and pharmacological effects of the noncompetitive

N-methyl-D-aspartate (NMDA) receptor antagonist ketamine have been used to study

important aspects of psychotomimetic action in humans.

 

Adjunctive Use of Ceftriaxone and Sodium Valproate in the Management of Tetanus: A Case Report and Literature Review

S Oriaifo, N Oriaifo, M Oriaifo, E Okogbenin, E Omogbai – Journal of Biology, …, 2015

immune globulin. Control of spasms was mainly by the use of the GABAergic-

enhancing drugs diazepam and sodium valproate combined with the use of the

anti-excitotoxics magnesium sulphate and ketamine. The introduction

 

PyBidine–NiCl2-Catalyzed Asymmetric Addition of Alcohols and Peroxides to Isatin-Derived Ketimines

T Arai, K Tsuchiya, E Matsumura – Organic Letters, 2015

adduct (27%, 80% ee). The formation of the chiral N,O-acetal inspired us to optimize

the reaction conditions for the addition of methanol to an isatin-derived

N-Boc-ketamine (1a), as shown in Table 1. Table 1. Optimization of

 

Radiofrequency Ablation (RFA)

 

Radiofrequency Ablation for Atrial Fibrillation: Trends in Patients, Clinical Outcomes, and Resources Among Medicare Beneficiaries from Fiscal Year 2010 to Fiscal …

MR Reynolds, AD Kugelmass, DJ Cohen, PP Brown… – … : Cardiovascular Quality and …, 2015

Abstract Introduction: The objective of this analysis was to report four year trends among

Medicare beneficiaries (MB) undergoing Radiofrequency Ablation (RFA) to treat Atrial

Fibrillation (AF). Methods: This retrospective study examined both the Medicare Provider

 

Systematic review and meta-analysis of perinatal outcomes following radiofrequency ablation and bipolar cord occlusion in monochorionic pregnancies

K Gaerty, RM Greer, S Kumar – American Journal of Obstetrics and Gynecology, 2015

Objective The aim of this study was to analyse perinatal outcomes following selective

reduction in monochorionic pregnancies using either radiofrequency ablation (RFA) or

bipolar cord occlusion (BCO). Study Design This was a systematic review and meta-

 

Sublobar Resection, Radiofrequency Ablation or Radiotherapy in Stage I Non-Small Cell Lung Cancer

S Safi, G Rauch, J Kunz, T Schneider, M Bischof… – Respiration, 2015

Background: The best therapy for patients with stage I non-small cell lung cancer (NSCLC)

who are medically unfit for lobectomy or prefer not to undergo surgery has not yet been

demonstrated. Objectives: We analyzed data from our prospective database to evaluate

 

The efficacy of radio-frequency ablation for metastatic lung or liver tumors of male germ cell tumors as an alternative minimally invasive therapy after salvage …

Y Naya, T Nakamura, M Oishi, T Ueda, H Nakanishi… – International Journal of …, 2015

Okuma et al. [14] reported that tumors under 20 mm in size can be completely ablated in lung

tumor. Cancer 3:1409–1419 7. Curley SA, Izzo F, Delrio P et al (1999) Radiofrequency ablation

of unresectable primary and metastatic hepatic malignancies. Results in 123 patients.

 

Metastastectomy for metachronous pulmonary and hepatic metastases from nasopharyngeal carcinoma: Report of 6 cases and review of the literature

SJM Lim, NG Iyer, LL Ooi, HN Koong, A Chung, HK Tan… – Head & Neck, 2015

not prevent disease progression in the long term. Surgery and radiofrequency ablation have ten

patients who underwent radiofrequency ablation +/- adjuvant chemotherapy had a median survival

period of 77.1 months compared to 32.4 months in another ten patients who only

 

[HTML] Lobulated Enhancement Evaluation in the Follow-Up of Liver Metastases Treated by Stereotactic Body Radiation Therapy

H Jarraya, P Borde, X Mirabel, O Ernst, T Boulanger… – International Journal of …, 2015

have limitations for the evaluation of targeted therapies; for example, imatinib for gastrointestinal

stromal tumors (GIST) and bevacizumab for colorectal liver metastasis 8, 9 and 10 or other local

treatments, such as lung tumor SBRT (11), liver radiofrequency ablation (12), and

 

Percutaneous microwave ablation of thyroid nodules: effects on thyroid function and antibodies

K Heck, C Happel, F Grünwald, H Korkusuz – International Journal of Hyperthermia, 2015

The results demonstrated that in all 30 sessions the complete volume of the 34

nodules could be ablated. The treatment al. Radiofrequency ablation of benign thyroid

nodules: Safety and imaging follow-up in 236 patients. Eur

 

Current state of the treatment of perforating veins

ED Dillavou, M Harlander-Locke, N Labropoulos… – Journal of Vascular Surgery: …, 2015

Table II. Technical success of radiofrequency ablation (RFA), endovenous laser ablation (EVLA),

and ultrasound-guided foam sclerotherapy (UGFS). Primary author (year), Perforator treatment

modality, No. 14, 15, 18 and 26. Radiofrequency ablation (RFA).

 

Irreversible Electroporation of the Pancreas Is Feasible and Safe in a Porcine Survival Model.

S Fritz, CM Sommer, D Vollherbst, MF Wachter… – Pancreas, 2015

From a histopathological point of view, the ablated area was character- ized by cellular eosinophila

The ability of IRE to ablate undesirable tissue near large blood vessels and damageable of the

electric field to which the tissue is exposed.13 Radiofrequency ablation has been

 

An Analysis of Patients Transferred to a Tertiary Oncological Intensive Care Unit for Defined Procedures

S Kamat, S Chawla, P Rajendram, SM Pastores… – American Journal of Critical …, 2015

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Complex Regional Pain Syndrome (CRPS/RSD)

 

Two Virtual Reality Pilot Studies for the Treatment of Pediatric CRPS

AS Won, CA Tataru, CM Cojocaru, EJ Krane… – Pain Medicine, 2015

Letter to the Editor. Two Virtual Reality Pilot Studies for the Treatment of Pediatric CRPS. How

to Cite. Won, AS, Tataru, CA, Cojocaru, CM, Krane, EJ, Bailenson, JN, Niswonger, S. and Golianu,

B. (2015), Two Virtual Reality Pilot Studies for the Treatment of Pediatric CRPS.

 

A dynamic PUF anti-aging authentication system based on restrict race code

B Li, S Chen – Science China Information Sciences, 2015

Based on the CRP mechanism, the PUF circuit can produce chip-unique responses when

challenges are applied to it and stored in the database by the way of CRPs. (2) Authentication.

The expected data in the database are called CRPs in paper.

 

Increased prevalence of two mitochondrial DNA polymorphisms in functional disease: Are we describing different parts of an energy-depleted elephant?

RG Boles, EA Zaki, JR Kerr, K Das, S Biswas… – Mitochondrion, 2015

Herein, we tested for these variants in chronic fatigue, CRPS, SIDS and depression. CVS = cyclic

vomiting syndrome, Fxn abd pain = functional abdominal pain (a common pediatric functional

syndrome), IBS = irritable bowel syndrome, CRPS = complex regional pain syndrome.

 

[HTML] TURAN and EVAN Mediate Pollen Tube Reception in Arabidopsis Synergids through Protein Glycosylation

H Lindner, SA Kessler, LM Müller, H Shimosato-Asano… – 2015

Abbreviations:: ConA, Concanavalin A; CRPs, cysteine-rich polypeptides; CrRLK1L, Catharanthus

roseus receptor-like kinase 1-like subfamily; DAE, days after emasculation; DAP, days after

pollination; DAPI, 4′,6-diamidino-2-phenylindole; DEFL, defensin-like protein; Dol-P

 

Facilitated spinal neuropeptide signaling and upregulated inflammatory mediator expression contribute to post-fracture nociceptive sensitization.

X Shi, T Guo, T Wei, W Li, DJ Clark, WS Kingery – PAIN, 2015

neuropeptide-dependent nociceptive and inflammatory changes in the hindlimbs of rats similar

to those seen in complex regional pain syndrome (CRPS). Inflammatory changes inflammatory

mediators contributing to nociceptive sensitization in a rodent fracture model of CRPS.

 

Ketamine-A Narrative Review of Its Uses in Medicine.

BM Radvansky, S Puri, AN Sifonios, JD Eloy, V Le – American Journal of Therapeutics, 2015

pain clinics, and in the prehospital realm. It has been used to treat postoperative pain, chronic

pain, complex regional pain syndrome (CRPS), phantom limb pain (PLP), and other neuropathic

conditions requiring anal- gesia. CRPS has remained a difficult-to-treat entity.

 

Trends in Coronary Revascularization Procedures among Medicare Beneficiaries between Fiscal Years 2010 and 2013

A Kugelmass, MR Reynolds, DJ Cohen, PP Brown… – … : Cardiovascular Quality and …, 2015

Mortality rates were highest and increasing for MBs presenting with STEMI across all procedures.

Conclusions: The overall volume of CRPs among MBs is declining and more MBs are presenting

with an AMI, and overall mortality rates are increasing year over year.

 

CORD STIMULATIONS IN PATIENTS WITH COMPLEX REGIONAL PAIN SYNDROME: A RANDOMIZED PLACEBO CONTROLLED TRIAL

N Kriek, J Groeneweg, D Stronks, F Huygen

N. Kriek, J. Groeneweg, D. Stronks, F. Huygen Center for pain management, Erasmus MC,

Rotterdam, The Netherlands Objectives: Spinal cord stimulation (SCS) is an effective invasive

therapy to treat neuropathic pain states including complex regional pain syndrome (CRPS).

 

[HTML] Diagnostic value of C-reactive protein to rule out infectious complications after major abdominal surgery: a systematic review and meta-analysis

SL Gans, JJ Atema, S van Dieren, BG Koerkamp… – International Journal of …, 2015

The posttest odds were calculated by multiplying the pretest odds with the positive and

negative LR. Posttest probabilities for a high and a low CRPs were calculated and presented

in a graph for pretest probabilities across the range of 0 to 100 %.

 

[HTML] World congress comes to you 7: Yes we can (control chronic pain)

V Bellan

If you want more information on CRPS you might find what we know about CRPS helpful as

well as these resources by the Royal College of Physicians. You can also read recent research

published by the team and browse through our CRPS blog articles.

 

Fibromyalgia

 

Factors Associated With Time to Diagnosis in Fibromyalgia

G Chodick, D Weitzman, Y Bar-On, V Shalev, H Amital – Journal of Patient-Centered …, 2015

Background/Aims: The diagnosis of fibromyalgia, a chronic debilitating disorder, is

complicated and affected by various factors of the patient and the caregiver. The objectives

of this study were to investigate the time passing from initial complaints to diagnosis and to

 

[PDF] Central Sensitization Syndrome and the Initial Evaluation of a Patient with Fibromyalgia: A Review

KC Fleming, MM Volcheck – Rambam Maimonides Med J, 2015

ABSTRACT In both primary care and consultative practices, patients presenting with

fibromyalgia (FM) often have other medically unexplained somatic symptoms and are

ultimately diagnosed as having central sensitization (CS). Central sensitization

 

Does low bone density influence symptoms and functional status in patients with fibromyalgia? Observations from rural South India

AS Babu, FM Ikbal, MS Noone, AN Joseph, D Danda – International Journal of …, 2015

Results Low BMD was seen in 81.6%(129/158) of the persons screened. FMS was seen in

37/158 persons, of which 31/37 (83.7%) had low BMD. Conclusion FMS with low bone

density leads to higher levels of pain and a poorer QoL compared to those without FMS.

 

[PDF] Walking as physical exercise in Fibromyalgia: An elicitation study from the Theory of Planned Behavior

MÁ Pastor, S López-Roig, Y Sanz, C Peñacoba – anales de psicología, 2015

Abstract: This study is the first phase of the formative research recommended in the Theory

of Planned Behavior for the development of an intervention. Our aims are to identify modal

beliefs about the performance of an exercise pattern in people with fibromyalgia, to test

 

… advances in spinal cord and brainstem fMRI provide an unprecedented view of human pain processing and alterations to pain mechanisms in fibromyalgia

R Bosma – 2015

Abstract: Functional MRI of the human spinal cord and brainstem has tremendous potential

to enhance our basic understanding of healthy subcortical function, and impact our ability to

accurately diagnose and treat injury and disease. Despite this potential, there are many

 

Understanding High Blood Pressure

S Aziz – 2015

 

Overcoming Low Self-Esteem with Mindfulness

D Ward – 2015

 

[HTML] Efficacy and processes of change in acceptance and commitment therapy for chronic pain

M Kemani – 2015

The first trial utilized a wait-list control condition and included women with fibromyalgia (Study

I). Assessments were done pre- and post-treatment and at 3-month follow-up. Acceptance and

commitment therapy for fibromyalgia: A randomized controlled trial.

 

[PDF] Evaluation of psychiatry consultations requested for inpatients in a university hospital

H Mayda, HI Guzel, Y Gorucu, E Bagcioglu – Bulletin of Clinical Psychopharmacology, 2015

[Abstract:0282] Psychosomatic disorders Metacognitive evaluation in patients with fibromyalgia

syndrome In this study, we tested the assumption that patients with Fibromyalgia Syndrome (FMS)

experience more metacognitive thoughts compared to healthy individuals.

 

[PDF] Investigation of state and trait anxiety levels among pharmacy students in TRNC

YH Balcıoglu, E Duran – Bulletin of Clinical Psychopharmacology, 2015

Bulletin of Clinical Psychopharmacology 2015;25(Suppl. 1):S93-S4 [Abstract:0452] Anxiety,

stress, and adjustment disorders Angiotensin-converting enzyme and

methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome

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