Weekly Breaking Research Updates, May 22, 2015


Scientific breakthroughs happen every day!  In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates.  The title of each article below is a link to the full study report.  If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.




[HTML] Exaggerated Acute Lung Injury and Impaired Antibacterial Defenses During Staphylococcus aureus Infection in Rats with the Metabolic Syndrome

X Feng, M Maze, LG Koch, SL Britton, J Hellman – 2015

All procedures were performed under ketamine and xylazine anesthesia, and all efforts

were made to minimize suffering. Animals. The edema. At 48 h, the rats were sacrificed

under deep anesthesia provided by ketamine/xylazine.


Drugs that Target the Glutamate Synapse: Implications for the Glutamate Hypothesis of Schizophrenia

CA MIELNIK, A RAMSEY – Drug Discovery for Schizophrenia, 2015

In addition to the ligand bind- ing domains, NMDA receptors have modulatory sites for

zinc and spermine, and a modulatory site within the channel that binds the

non-competitive inhibitors phencyclidine (PCP), dizocilpine, and ketamine.



TJ Smyser, SR Johnson, MD Stallard, AK McGrew… – Journal of Wildlife Diseases, 2015

lactating were released at the capture location. We anesthe- tized captured raccoons

with ketamine/xyla- zine (10 mg/kg ketamine and 2 mg/kg xylazine, intramuscularly

[Fowler 2009]). Upon induc- tion, animals were weighed


[PDF] Intra-ventral tegmental HIV-1 Tat1-86 attenuates nicotine-mediated locomotor sensitization and alters mesocorticolimbic ERK and CREB signaling in rats

J Zhu, NM Midde, AM Gomez, W Sun, SB Harrod – Name: Frontiers in Microbiology, 2015

session 29 (Fig 1A). 30 Briefly, rats were anesthetized using a mixture of ketamine

hydrochloride and xylazine 31 by intraperitoneal (IP) injection (7.5 mg ketamine/100

g b.wt. and 30 mg xylazine/100 g b.wt.). 32 Rats were then


Autonomic remodeling: How atrial fibrillation begets atrial

L Zhang, SS Po, HW PhD&, BJ Scherlag, HL PhD&… – 2015

13 Fifty-two male adult New Zealand white rabbits, weighing 2.0–2.5 kg, were 14 premedicated

with ketamine/xylazine ( 35mg/5mg/kg ),and restrained in the 15 supine position. Anesthesia

was also maintained by intra-peritoneal injection of 16 20% urethane 5 ml as needed.


Protein Interactions with Dopamine Receptors as Potential New Drug Targets for Treating Schizophrenia

P SUa, AHC WONG, F LIU – Drug Discovery for Schizophrenia, 2015

Page 222. Chapter 9 208 antagonist, ketamine, or PCP-induced cognitive deficits with an

inverted U-shaped dose response curve. 52 Conversely, there is less ketamine-induced

behavioral activation in D1R knockout mice than in wild-type mice.


Plasma arginine metabolites reflect airway dysfunction

H Grasemann, JA Scott, ML North, M Rafii, H Huang… – J Appl Physiol, 2015

On day 21, 24 h after the final aerosol challenge, mice were anesthetized (ketamine/xylazine)

for tracheal and jugular venous cannulations for ventilator-based measurement of respiratory

function and infusion of the stable L-arginine isotopomer cocktail, respectively.


[PDF] Histological and Histomorphometric Evaluation of Pharmacological Action of the Essential Oil of Melaleuca Alternifolia on Healing of Infected Alveolitis in Experimental …

WS Abdel-fattah, MM Dahaba, AA Ahmed… – J Interdiscipl Med Dent Sci, 2015

Materials and Methods Chemicals Tea tree oil was purchased from (SIGMA-ALDRICH

Chemie GmbH RiedstrasseUSA), vancomycin hydrochloride and ketamine were

obtained from the local pharmaceutical market. Bacterial infection


[PDF] Clinical Evaluation of Caudal Clonidine as an Adjuvant to Bupivacaine in Pediatric Patients Undergoing Sub Umbilical Surgeries

S Dalal – 2015

Prolongation of caudal analgesia using a single-shot technique has been achieved by addition

of various adjuvants, such as epinephrine, opioid, ketamine, and alpha 2 agonists [9]. Clonidine,

an alpha 2 agonist has extensively been used in neuraxial blocks [10- 13] and


The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats

E Taslidere, N Vardi, M Esrefoglu, B Ates, C Taskapan… – Human & Experimental …, 2015

kg body weight for 20 days. At the end of the experiment, rats were killed by ketamine

anesthesia. After blood samples were collected from tail vein, livers were removed

and divided into two portions. One sample was used for


[PDF] Assessment of the effect of ketamine on cytochrome P450 isoforms activity in rats by cocktail method

F Lin, Y He, L Zhang, M Zhang, Y Zhang, C Wen – Int J Clin Exp Med, 2015

Abstract: Cocktail method was used to evaluate the influence of ketamine on the activities of

CYP450 isoforms CYP1A2, CYP2D6, CYP3A4, CYP2C19, CYP2C9 and CYP2B6, which

were reflected by the changes of pharmacokinetic parameters of six specific probe drugs


Ketamine and suicidal ideation in depression: Jumping the gun?

R Rajkumar, J Fam, EYM Yeo, GS Dawe – Pharmacological Research, 2015

Abstract Depression and suicide are known to be intricately entwined but the

neurobiological basis underlying this association is yet to be understood. Ketamine is an N-

methyl D-aspartate (NMDA) receptor antagonist used for induction and maintenance of


Ketamine-mediated alleviation of electroconvulsive shock-induced memory impairment is associated with the regulation of neuroinflammation and soluble amyloid- …

X Zhu, P Li, X Hao, K Wei, S Min, J Luo, F Xie, J Jin – Neuroscience Letters, 2015

Abstract Electroconvulsive therapy (ECT) is an effective treatment for depression, but can

result in memory deficits. This study aimed to determine whether ketamine could alleviate

electroconvulsive shock (ECS, an analogue of ECT in animals)-induced memory


D-AMPHETAMINE withdrawal-induced decreases in brain-derived neurotrophic factor in sprague-dawley rats are reversed by treament with ketamine

JJL Fuller, RC Murray, KA Horner – Neuropharmacology, 2015

Abstract Withdrawal from chronic D-amphetamine (D-AMPH) can induce negative emotional

states, which may contribute to relapse and the maintenance of addiction. Diminished levels

of brain-derived neurotrophic factor (BDNF), particularly in the hippocampus has been


Management of acute pain in patients on treatment with opioids

J De Andres, G Fabregat-Cid, JM Asensio-Samper… – Pain Management, 2015

In fact, the use of NMDA receptor antagonists such as ketamine inhibits the development of

tolerance in test animals [15]. Inhibition of tolerance has been demonstrated in test animals with

the use of noncompetitive antagonists of NMDA receptors such as ketamine [48].



T Ha, L Abbott, J Booth, M Morrow, M Rawlins… – 2015

Emerg Med J 2014; 31: 706–13. Ketamine and Intraocular Pressure in Children This prospective

observational study sought to examine the potential increase in the intraocular pressure following

ketamine administration for paediatric procedural seda- tion.


Multimodal Analgesic Protocol and Postanesthesia Respiratory Depression During Phase I Recovery After Total Joint Arthroplasty.

TN Weingarten, AK Jacob, CW Njathi, GA Wilson… – Regional Anesthesia and …, 2015

Procedural sedation during block placement was with incremental dosing of intravenous midazo-

lam, fentanyl, and ketamine. Use of ketamine as a sedative for nerve blockade or analgesia was

at the discretion of the attending anesthesiologist and not part of the protocol.


Stem cell-based therapies for intracerebral hemorrhage in animal model: a meta-analysis

X Ma, J Qin, B Song, C Shi, R Zhang, X Liu, Y Ji, W Ji… – Neurological Sciences, 2015

CAMARADES) [10]: peer- reviewed publication; statement of control of tem- perature; random

allocation to treatment or control; blinded induction; blinded assessment of outcome; use of

anesthetic without significant intrinsic neuroprotec- tive activity (such as ketamine); use of


Anatomical organization of the visual dorsal ventricular ridge in the chick (Gallus Gallus): Layers and columns in the avian pallium

P Ahumada‐Galleguillos, M Fernandez, GJ Marin… – Journal of Comparative …, 2015

Deposits of biocytin in vital slices. Forty chicks (P1-P5) were deeply anesthetized with a mixture

(3:1) of 1% Ketamine and 2% Xylazine, and then decapitated. Deposits of DiI in fixed slices. Ten

chicks were deeply anesthetized using the Ketamine/Xilazine mixture and perfused


[PDF] Alterations in molecular pathways in the retina of early experimental glaucoma eyes

L Cao, L Wang, G Cull, A Zhou – Int J Physiol Pathophysiol Pharmacol, 2015

in one eye of each animal under ketamine and xyla- zine anesthesia. One hundred follow-

up. During each test, IOP was measured by a rebound tonometer (Tonopen XL, Reichert

Inc) under ketamine and xylazine anesthesia. The peripapillary


Radiofrequency Ablation (RFA)


… K Antagonist Oral Anticoagulants versus Vitamin K Antagonist Oral Anticoagulants in Patients Undergoing Radiofrequency Catheter Ablation of Atrial Fibrillation: A …

G Santarpia, S De Rosa, A Polimeni, S Giampà… – PloS one, 2015

BACKGROUND: Use of the non-vitamin K antagonist oral anticoagulants (NOACs) is

endorsed by current guidelines for stroke prevention in patients with atrial fibrillation (AF).

However efficacy and safety of NOACs in patients undergoing catheter ablation (RFCA) of


Treatment of Renal Cell Carcinomas

SN Kurukkal, SS Al-Busaidy – Urological Cancer Management, 2015

cavitational ultrasound (PCU). However, only two ablation therapies are recommended

by expert panels for the treatment of renal tumours: cryoablation and radiofrequency

ablation. hilum. 16.3.1 Radiofrequency Ablation (RFA). It is


[PDF] Metastatic Colorectal Cancer: Review of Diagnosis and Treatment Options

M Palaghia, CC Prelipcean, E Cotea, N Vlad… – Journal of Surgery [Jurnalul …, 2015

Liver Metastases: Addition of new, multidisciplinary techniques and therapies like systemic or

local chemotherapy, radiofrequency ablation (RFA), cryotherapy and radiotherapy improves the

rate of liver metastases resectability but currently there is no gold standard concerning


ть е рыв ж ть

H Takeuchi – 2015

transplantation and as a radiofrequency ablation for AF [3]. Sixty-four-slice multidetector CT

(64-MDCT) becomes an option to evaluate coronary artery stenosis. pulmonary venous stenosis

following radiofrequency ablation. Respiratory Care 2004; 49:1525-7.


[PDF] The natural product sulforaphane inhibits breast cancer stem cell targets in triple negative and trastuzumab-resistant breast cancers

J Burnett – 2015

metastasis (1). Substantial progress has been made with respect to the treatment of primary

tumors using surgery, chemotherapy, radiation therapy, and radiofrequency ablation. However,

the advancement of cancer to an invasive or metastatic stage is


[HTML] Multidisciplinary management of advanced lung neuroendocrine tumors

PL Filosso, P Ferolla, F Guerrera, E Ruffini, WD Travis… – Journal of Thoracic Disease, 2015

In the absence of hormonal control, many patients may benefit of SSA or Interferon,

associated with loco-regional therapies (liver palliative surgery, radiofrequency metastasis

ablation or trans arterial chemoembolization). Low-grade NETs.


[PDF] Minimally-invasive Therapy in Thyroid Practice

L Hegedüs

Ethanol ablation (PEI) • Laser ablation (ILP) • Radiofrequency ablation (RFA • Laszlo Hegedüs •

Enrico Papini (Rome, Italy) • Jung Hwan Baek (Seoul) Ford T Maserati Quatroporte Proto Spirra

Radiofrequency Ablation (RFA) Page 21. 5/13/2015 21 P < 0,0001 RFA Obs.


[PDF] 0915-0940 TBD 0940-1000 Coffee break/Poster viewing

M Kudo, G Abou-Alfa, O Baatarkhuu, RN Chien… – Surgery

Prof Ho Yeong Lim (Korea) 1535-1555 Novel techniques: ablation Dr Shuichiro

Shiina (Japan) Circulating biomarkers Dr Wei Tang (Japan) 1555-1615 Surgery

vs. ablation: a new balance in the era of new technologies?


Urological Cancer Management

SA Al-Mamari, SS Al-Busaidy

time PSM Positive surgical margins PTH-rP Parathormone-related peptide pTNM Pathological

TNM QoL Quality of life RALP Robotic assisted laparoscopic radical prostatectomy RC Radical

cystectomy RCC Renal cell carcinoma RFA Radiofrequency ablation RN Radical


[DOC] Deliverable 11

B Plan

Introduction. Ablatech Inc. is a novel company developing a direct current (DC) Ablation device

for the treatment of fibroadenomas and lipomas. Note: The DC Ablation generator is indicated

for use with Ablatech’s A2500 series of delivery needles, which are sold separately.


Radiofrequency ablation for treatment of hereditary hemorrhagic telangiectasia lesions:“How I do it”

B Rotenberg, S Noyek, CJ Chin – American Journal of Rhinology & Allergy, 2015

Introduction: Hereditary hemorrhagic telangiectasia (HHT) can cause significant epistaxis for

those that suffer from it. Traditaional surgical treatments are ablative and can cause thermal

damage. Radiofrequency (RF) energy can potentially be used to ablate HHT plaques at a


Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients

A Facciorusso, V Del Prete, N Crucinio, N Muscatiello… – Journal of Gastroenterology …, 2015

Methods Data on 153 patients were reviewed. The study population was classified into three

groups: 73 (47.8%) patients who received neither angiotensin converting enzyme inhibitors

nor sartans (Group 1), 49 (32%) patients treated with angiotensin converting enzyme


Ablative therapies: Advantages and disadvantages of radiofrequency, cryotherapy, microwave and electroporation methods, or how to choose the right method for an …

O Seror – Diagnostic and Interventional Imaging, 2015

It is important, however, to understand that each of the ablated regions created remains as possible

the functional liver parenchyma which implies to not ablate too large No touch multibipolar

radiofrequency ablation for single liver metastases: a: axial computed tomography at


Pulmonary Vein Stenosis After Minimally Invasive Stand‐alone Surgical Ablation of Atrial Fibrillation

E Abo‐salem, J Munjal, S Kapur – Journal of Cardiac Surgery, 2015

vein. In our case, several rounds of cryoablation alternating with radiofrequency ablation

were also applied to confirm a transmural block. An extensive ablation strategy may

have contributed to the development of stenosis. Aggressive


[PDF] Comparative study between conventional chemo-embolization and chemo-embolization using drug eluting beads as alternative methods for treatment of …

RS Elshahat, HA Ahmed, OI Saleh, EEA Ibrahim… – Life Science Journal, 2015

Although preliminary screening and diagnosis have allowed HCC patients to benefit from radical

resection, transplantation, or radiofrequency ablation, tumors in some patients still progress rapidly

because of local spreading or metastases, particularly in those with background


Treatment of hepatocellular carcinomas by thermal ablation and hepatic transarterial chemoembolization

P Chevallier, G Baudin, R Anty, A Guibal, M Chassang… – … and Interventional Imaging, 2015

It has now been shown for monopolar radiofrequency ablation that this therapy

alone is sufficient to effectively treat single HCCs < 3 cm in diameter provided that

liver micrometastases are not present. If the HCC is >3 cm in


The “Duality” of Idiopathic Ventricular Arrhythmias from the Left Ventricular Ostium

DJ Callans, P Santangeli – Pacing and Clinical Electrophysiology, 2015

LBBB, the other RBBB which were ablated from a single region. These patients were identified

from a series of 247 patients with idiopathic outflow tract PVCs. The methods included

electroanatomic mapping, irrigated radiofrequency ablation and site verification


nonsystemic treAtment of Liver metAstAses from neuroendocrine tumor

D Putzer, G Widmann, D Waitz, W Jaschke, IJ Virgolini – … Analogues: From Research …, 2015

274 NONsYsTEMIC TREATMENT Of LIVER METAsTAsEs RfA radiofrequency ablation RILD

radiation‐induced liver disease sIRT selective internal radiation therapy sPECT single photon

emission computed tomography TACE transarterial chemoembolization Us ultrasound


Interventional oncology for liver and lung metastases from colorectal cancer: The current state of the art

T de Baere, L Tselikas, E Pearson, S Yevitch, V Boige… – … and Interventional Imaging, 2015

tissue causes cooling through convention, which is responsible for the “heat sink effect”, and

causes difficulties in ablating tissue close to The hepatic recurrence rate in 6025 patients

undergoing surgery with or without radiofrequency ablation for malignant liver metastases from


One Year Incidence of Atrial Septal Defect After PV Isolation: A Comparison Between Conventional Radiofrequency and Cryoballoon Ablation

G Mugnai, J Sieira, G Ciconte, MS Hervas, G Irfan… – Pacing and Clinical …, 2015

Background: Transseptal (TS) catheterization is needed to access the left heart during

pulmonary vein isolation (PVI) procedures. In the radiofrequency (RF) ablation procedure,

left atrial access is commonly achieved with a double TS puncture; cryoballoon (CB)



Complex Regional Pain Syndrome (CRPS/RSD)


[PDF] Topics on estimation, prediction and bounding risk for multivariate extremes

RA Yuen – 2015

17 2.3 CRPS M-estimation for max-stable models . . . . . 20 2.4 Simulation . . . . . 141

A.1 Code for fitting max-linear models via CRPS . . . . . 142 A.2 Code for fitting a

Tawn-Molchanov max-stable model . . . . 144 BIBLIOGRAPHY . . . . .



DK Garas, MD Rano Faltas, ER Viscusi

refractory CRPS, and has been found to be particularly efficacious6. • In a study

of 25 patients with refractory CRPS who underwent surgery, IV ketamine

exacerbations or spread of their CRPS at their 3 month evaluation6, 13.


[PDF] Preliminary Port Recovery Plan Schedule 2: Regional Coastal Environment Plan for the Canterbury Region (RCEP) Provisions-Specific Changes Sought (or wording …

L Port, P Page – policy

for by policies, rules and other methods set out in the RCEP. These changes sought are consistent

with the CRPS as set in Schedule 1. These changes sought are consistent with the CRPS as set

out in Schedule 1. Amendments sought to Action 7 are Insert a new policy:


Organisational Complaint Management

S Garding, A Bruns – Complaint Management and Channel Choice, 2015

2013). Garnefeld et al. (2013) even recommend companies to consider “building CRPs

into social media campaigns to take advantage 6 1 Organisational Complaint

Management Page 7. of the increasing social commerce opportunities”.


[PDF] Reverse total shoulder arthroplasty for complex proximal humeral fractures in the elderly: How to improve outcomes and avoid complications

RPDM UCT, F Ortho, UCT MMed Orth, BVM Zim, F Orth… – pain

139 (90–180) – 27 (0–45) 1 (VAS) 10% 1 patient with CRPS, DVT, and GT resorption, 1 patient

with GT malunion, 1 patient with Grade 1 notching ASES 78 T a b le I: R esu lts o RTSA 9

133(±20) 41 (±19) 1 (±1) 1/9 CRPS (recovered) ASES 80 (±11) T a b le II: R esu lts fo r stu


[PDF] Syringomyelia & Spinal Cord Stimulation

RB Pitkanen, DL James

found to be successfully used in the treatment of several neuropathic pain syndromes

such as radiculopathy, failed back surgery syndrome, CRPS, post-herpetic neuralgia,

as well as to a lesser extent for chronic migraine, refractory


[PDF] Neuropsychology of Chronic Pain

EM Desensitization

For example, com- plex regional pain syndrome (CRPS) is caused by a disturbance of the

sympathetic nervous system— the network of nerves located along the spinal cord that controls

bodily functions such as the opening and closing of blood vessels and sweat glands.


Stefan Garding Andrea Bruns


2013). Garnefeld et al. (2013) even recommend companies to consider “building CRPs

into social media campaigns to take advantage 6 1 Organisational Complaint Management

Page 19. of the increasing social commerce opportunities”.


” What I really needed was the truth”. Exploring the information needs of people with Complex Regional Pain Syndrome

S Grieve, C McCabe, J Adams – Musculoskeletal Care, 2015

Download (52Kb) | Request a copy: Description/Abstract. Background United Kingdom

guidelines indicate individuals with Complex Regional Pain Syndrome (CRPS) require

information and education to support self management.


Reprogramming of in situ spinal cord stimulator for covering newly developed postthoracotomy pain

NN Knezevic, MV Rana, P Czarnocki… – Journal of Clinical …, 2015

Postthoracotomy pain; Spinal cord stimulation. 1. Introduction. Spinal cord stimulation has become

increasingly successful in the treatment of pain syndromes, especially neuropathic pain, ranging

from failed back surgery syndrome to complex regional pain syndrome (CRPS).


Late Amputation May Not Reduce Complications or Improve Mental Health in Combat-Related, Lower Extremity Limb Salvage Patients

CA Krueger, JC Rivera, DJ Tennent, AJ Sheean… – Injury, 2015

Table 2. Documented reasons of why the limb salvage patients wanted a late amputation. CRPS:

Chronic Regional Pain Syndrome. Reasons for Desired Late Amputation, (n, %), Lack of joint

motion, 6, 13%. Lack of strength, 4, 9%. Skin coverage or flap failure, 2, 5%. CRPS, 1, 2%


Community-Based Review of Research Across Diverse Community Contexts: Key Characteristics, Critical Issues, and Future Directions

N Shore, A Ford, E Wat, M Brayboy, ML Isaacs, A Park… – American Journal of Public …, 2015

These community-based research review processes (CRPs) can provide individual and

community-level ethics protections, enhance the cul- tural relevance of study de- signs and

competence of re- searchers, build community and academic research capac- ity, and shape


Bayesian Model Averaging with Stratified Sampling for Probabilistic Quantitative Precipitation Forecasting in Northern China during Summer 2010

J Zhu, F Kong, L Ran, H Lei – Monthly Weather Review, 2015

Page 1. Monthly Weather Review EARLY ONLINE RELEASE This is a preliminary PDF of

the author-produced manuscript that has been peer-reviewed and accepted for publication.

Since it is being posted so soon after acceptance, it has not yet been



H Tabuteau – US Patent 20,150,133,485, 2015

In some embodiments, a combination of dextromethorphan and an antidepressant, such as

bupropion, may be administered to relieve complex regional pain syndrome, such as complex

regional pain syndrome type I (CRPS-I), complex regional pain syndrome type II (CRPS-II



H Tabuteau – US Patent 20,150,133,486, 2015

In some embodiments, a combination of dextromethorphan and an antidepressant, such as

bupropion, may be administered to relieve complex regional pain syndrome, such as complex

regional pain syndrome type I (CRPS-I), complex regional pain syndrome type II (CRPS-II


Osteoclast Inhibitors for Knee Conditions

H Tabuteau, G Jones – US Patent 20,150,133,403, 2015

embodiments, an osteoclast inhibitor, such as a nitrogen-containing bisphosphonate, eg

zoledronic acid, ibandronic acid or minodronic acid, may be administered to relieve complex

regional pain syndrome, such as complex regional pain syndrome type I (CRPS-I), complex


Neuroimaging-based biomarker discovery and validation.

CW Woo, TD Wager, CW Woo – PAIN, 2015

Neuroimage 2008;40(2):788-795. [11] Geha PY, Baliki MN, Harden RN, Bauer WR, Parrish

TB, Apkarian AV. The brain in chronic CRPS pain: abnormal gray-white matter interactions

in emotional and autonomic regions. Neuron 2008;60(4):570-581.


[PDF] IASP Interprofessional Pain Curriculum Outline

N Kariuki, J Miró, L Niemi-Murola, G Ochoa…

Primary Lesion Peripheral • degenerative disc disease with radiculopathy in neck and low back •

peripheral neuropathies (diabetes, cancer, alcohol, HIV) • post herpetic neuralgia • acute disc

herniation with radiculopathy • complex regional pain syndrome II (CRPS II) (causalgia




Inflammatory Allied Conditions

MA Oliveira, A Ciechomska – Musculoskeletal Ultrasonography in Rheumatic …, 2015

biopsies. Whereas in fibromyalgia, there are conflicting data about the utility of US,

and if used, it is mainly to exclude other causes of pain. XXXIX. Sonographic assessment

of hip in fibromyalgia patients. Clin Exp Rheumatol 30: pp.


Childhood adversity and illness progression in bipolar disorder

J Bücker, M Kauer-Sant’Anna, LN Yatham – Neuroprogression and Staging in Bipolar …, 2015

BD patients with a history of childhood adversity also seem to report comorbidity with numerous

medical conditions, including allergies, arthritis, asthma, chronic fatigue syndrome, chronic

menstrual irregularities, fibromyalgia, head injury, hypotension, irrit- able bowel syndrome


The Use of Motivational Interviewing in Physical Therapy Education and Practice: Empowering Patients Through Effective Self-Management

RM Pignataro, PT James Huddleston – Journal of Physical Therapy Education, 2015

been successfully employed in promoting adherence to a walking program in patients receiving

chemotherapy for breast cancer,42 in improving health promotion behaviors among people with

coronary risk factors,42 and in promoting exercise in patients with fibromyalgia.39 In


[PDF] Temporomandibular Joint Dysfunction

J Poduval – JMR, 2015

J Craniomandib Disord 1992, 6:301-355. 4. Truta MP, Santucci ET, Donlon WC. Head

and Neck fibromyalgia and temporomandibular arthralgia. In: Jacobson AL, Donlon WC,

(Eds). Headache and Facial Pain. New York: Raven, 1990:141.


From the Desk of Dr. Karl ROS Johnson, DC…..

ROS Karl

Intentional musings of a unique Shelby Township Michigan Chiropractic Physician dedicated

to helping people find solutions to improving their health by rooting out causes to chronic

conditions such as fibromyalgia, thyroid disorder symptoms, balance disorders, migraines


Ankylosing Spondylitis

M Backhaus, Y El Miedany – Musculoskeletal Ultrasonography in Rheumatic …, 2015

Beside spondyloarthritis patients, enthesitis have been reported among athletes

as a consequence of traumatic injuries. Distinguishing fibromyalgia tender points

from enthesitis is another important challenge to be considered.


[HTML] Development of a Learning-Oriented Computer Assisted Instruction Designed to Improve Skills in the Clinical Assessment of the Nutritional Status: A Pilot Evaluation

LG de Diego, M Cuervo, JA Martínez – 2015



[PDF] P1. Community-Clinical Linkages in the WISEWOMAN Program

K Ahmed, I Vaid, D May, D Manheim – JOURNAL OF WOMEN’S HEALTH, 2015

this study. Of the women patients, 361 reported a history of hysterectomy. A

comparison group consisted of 361 patients with a primary diagnosis of headache

or fibromyalgia without history of hysterectomy. Patients completed


[HTML] The Hot Sauce: Peppers and Fat Loss

VR Prisk

Aside from deterrence of muggers and bets between friends, there are many therapeutic

applications of capsaicin. Capsaicin creams, which desensitize nerves over time, are used

to treat neuropathy, shingles, psoriasis, arthritis pain and fibromyalgia.



AG Büyüktür – 2015

al., 2010; Hubbard et al., 2010), motor neuron disease (eg Locock et al., 2009), chronic fatigue

syndrome and fibromyalgia (eg Asbring, 2001), HIV infection (eg Anderson et al., 2010; Wilson,

2007), and multiple sclerosis (eg Green et al., 2007), among others.


34 Fibromyalgia, Chronic Fatigue, Functional Disorders, and Vaccination: Where Do We Stand?

JN Ablin, D Buskila – Vaccines and Autoimmunity, 2015


Gender and psychosocial context as determinants of fibromyalgia symptoms (fibromyalgia research criteria) in young adults from the general population

S Lourenço, L Costa, AM Rodrigues, F Carnide… – Rheumatology, 2015

Objective. To quantify the prevalence of FM (FM research criteria), to describe its

components—symptom severity score (SSS) and widespread pain index (WPI)—and to

identify biopsychosocial predictors of the severity of SSS as well as WPI using a


Fibromyalgia and the Risk of a Subsequent Motor Vehicle Crash

DA Redelmeier, JD Zung, D Thiruchelvam… – The Journal of …, 2015

Objective Motor vehicle crashes are a widespread contributor to mortality and morbidity,

sometimes related to medically unfit motorists. We tested whether patients diagnosed with

fibromyalgia (FM) have an increased risk of a subsequent serious motor vehicle crash.


Association of antithyroid peroxidase antibody with fibromyalgia in rheumatoid arthritis

J Ahmad, H Blumen, CE Tagoe – Rheumatology International, 2015

Abstract To investigate how autoimmune thyroiditis (ATD) affects the clinical presentation of

established rheumatoid arthritis (RA) with particular reference to fibromyalgia and chronic

widespread pain (CWP). A cohort of 204 patients with RA for whom the presence or


Association between fibromyalgia and thyroid autoimmunity

N Shirzad, S Movassaghi, H Karmostaji, F Esfahanian… – 2015

Fibromyalgia is a disorder characterised by fatigue, generalised body pain and cognitive

symptoms, and the aetiology has not been clearly described. Because similar symptoms are

frequently found in Hashimoto’s thyroiditis and there is not an optimal response to the



M Kandula – US Patent 20,150,133,408, 2015

Abstract: The invention relates to the compounds of formula I or its pharmaceutical

acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates

thereof. The pharmaceutical compositions comprising an effective amount of compounds



SB de Lorena, MCC de Lima, A Ranzolin, ÂLBP Duarte – rev bras reumatol, 2015

Review article Effects of muscle stretching exercises in the treatment of fibromyalgia: a systematic

review articleinfo Article history: Received 16 March 2014 Accepted 17 August 2014 Available

online 6 January 2015 Keywords: Fibromyalgia Stretching Physiotherapy abstract


36 Infections, Vaccinations, and Chronic Fatigue Syndrome

H Mahagna, N Mahroum, H Amital – Vaccines and Autoimmunity, 2015



MP Czech, M Wang – US Patent 20,150,133,520, 2015

12. The method of claim 11, wherein the muscle disorder is selected from the group consisting

of: muscle atrophy, muscle weakness, myopathy, chronic fatigue syndrome, fibromyalgia, muscular

dystrophy, fatigue fibromyalgia, spinal muscle atrophy, distal muscular dystrophy


27 Aluminum Particle Biopersistence, Systemic Transport, and Long-Term Safety: Macrophagic Myofasciitis and Beyond

RK Gherardi, J Cadusseau, FJ Authier – Vaccines and Autoimmunity, 2015