by admin | Sep 23, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
[HTML] Upper urinary tract damage caused by ketamine snorting—A report of nine cases
HY Lee, YC Hsu, CY Hsu, ECL Chou, CC Li, YS Juan… – Urological Science, 2015
Objective The toxicity of ketamine to genitourinary system not only involved in lower urinary
tract, which include urinary frequency, urgency, suprapubic pain, dysuria and hematuria, but
also upper urinary tracts. However, the reports of ketmaine-induced upper urinary tract …
Inconsistency of allometric scaling for dissociative anesthesia of wild felids
AB Carregaro, GC Freitas, SP Bisetto, NV Xavier… – Veterinary anaesthesia and …, 2015
… Keywords: allometric scaling; dissociative anesthesia; ketamine; metabolic rate; xylazine.
Abstract. … Objective. To evaluate allometric scaling for ketamine–xylazine (KX) anesthesia
in wild felids using domestic cats for reference. Study design. …
[PDF] The ERα-PI3K Cascade in Pro-opiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice
L Zhu, P Xu, X Cao, Y Yang, AO Hinton Jr, Y Xia… – Endocrinology, 2015
… Hypothalamic ER -p85 interaction and phosphorylation of AKT in response to icv PPT
Female C57Bl6 mice (12 weeks) were anesthetized with ip injections of
ketamine/xylazine cocktail (100 mg/kg ketamine and 10 mg/kg xylazine). …
[HTML] Effects of leptin on sympathetic nerve activity in conscious mice
DA Morgan, F Despas, K Rahmouni – Physiological Reports, 2015
… Here, we examined the sympathetic responses evoked by leptin in conscious mice. Mice
were instrumented, under ketamine/xylazine anesthesia, with renal or lumbar SNA
recordings using a thin (40 gauge) bipolar platinum–iridium wire. …
[PDF] Treatment of Pain with Antidepressants
B Kerr, C Benson, K Mifflin, SJB Jesudasan, S Dursun… – Klinik Psikofarmakoloji …, 2015
… depression43-45. There has been a great deal of interest in the NMDA receptor antagonist
ketamine and its rapid acting antidepressant action when infused46,47, and it is interesting that
this drug has also been used in treatment of therapy-resistant chronic pain48. …
Use of LigaSure on bile duct in rats. An experimental study.
A Marte, L Pintozzi – Minerva pediatrica, 2015
… in rats. MATERIALS AND METHODS: Thirty Wistar rats weighing 70 to 120gr were
employed for this study. The animals were all anaesthetized with intraperitoneal
Ketamine and then divided into three groups. The first group …
[HTML] Maxcal-C (a polyherbal formulation) prevents ovariectomy-induced osteoporosis in rats
RA Maheshwari, F Dhakwala, R Balaraman, AK Seth… – Indian Journal of …, 2015
… Standard drug Calcium Sandoz (cholecalciferol), ketamine hydrochloride, diazepam, povidone,
and ampicillin were purchased from commercial market. … The rats were anesthetized with injection
of ketamine hydrochloride (40 mg/kg. ip) and diazepam (5 mg/kg, im). …
Positive reinforcing effect of oxytocin microinjection in the rat central nucleus of amygdala
K László, A Kovács, O Zagoracz, T Ollmann, L Péczely… – Behavioural Brain Research, 2015
… 00 h. 2.2. Surgery. Rats were anesthetized ip by ketamine supplemented with
diazepam (Calypsol and Seduxen, Richter Gedeon, Hungary, ketamine: 80
mg/kg body weight, diazepam: 20 mg/kg body weight). Animals were …
Minocycline Attenuates Depressive‐like Behaviour Induced by Rat Model of Testicular Torsion: Involvement of Nitric Oxide Pathway
SSS Saravi, SE Mousavi, SSS Saravi, AR Dehpour – Basic & Clinical Pharmacology & …, 2015
… Testicular Torsion/Detorsion Animals were anaesthetized with intraperitoneal injection of ketamine
HCl (50 mg/kg) and chlorpromazine (25 mg/kg). … 30 days. Testosterone assay At day 30, the rats
were anaesthetized with intraperitoneal injection of ketamine HCl (50 mg/kg) …
Spinal Reflexes and Windup In Vitro: Effects of Analgesics and Anesthetics
I Rivera‐Arconada, C Roza, JA Lopez‐Garcia – CNS Neuroscience & Therapeutics, 2015
… Spinal cord mechanisms may contribute toward analgesia and akinesia. Ketamine.
The general anesthetic ketamine is a noncompetitive blocker of NMDA receptors
that also shows activity on several ionic channels. As expected …
Augmentation Therapy With Serial Intravenous Ketamine Over 18 Months in a Patient With Treatment Resistant Depression.
S Hassamal, M Spivey, AK Pandurangi – Clinical Neuropharmacology, 2015
Abstract Major depressive disorder is a severe illness that affects 3% to 7% of adults
annually in the United States. About 30% of these individuals are refractory to multiple
treatment trials. Recent reports have found a significant and almost immediate …
Ketamine Increases Permeability and Alters Epithelial Phenotype of Renal Distal Tubular Cells Via a GSK‐3β‐Dependent Mechanism
HY Shyu, CJ Ko, YC Luo, HY Lin, SR Wu, SW Lan… – Journal of Cellular …, 2015
Abstract Ketamine, a dissociative anesthetic, is misused and abused worldwide as an illegal
recreational drug. In addition to its neuropathic toxicity, ketamine abuse has numerous
effects, including renal failure; however, the underlying mechanism is poorly understood. …
More effective induction of anesthesia using midazolam-butorphanol-ketamine-sevoflurane compared with ketamine-sevoflurane in the common marmoset monkey ( …
H ISHIBASHI – Journal of Veterinary Medical Science, 2015
The common marmoset has been increasingly used for research in the biomedical field;
however, there is little information available regarding effective methods of anesthesia in this
species. This study retrospectively analyzed 2 regimens of anesthesia induction: …
[HTML] Comparison of Ketamine–Medetomidine-butorphanol and Ketamine–dexmedetomidine-butorphanol Anesthesia in Rats
R Costea, D Lastofka, M Mehedinţu – Agriculture and Agricultural Science Procedia, 2015
Abstract We evaluated the effect of ketamine-dexmedetomidine-butorphanol (K, 80 mg/kg;
D, 0.25 mg/kg, B, 0.5 mg/kg) and ketamine-medetomidine-butorphanol (K, 80 mg/kg; M, 0.25
mg/kg, B, 0.5 mg/kg) administered intraperitoneally, during anesthesia and immediate …
Pulmonary immunostimulation with MALP-2 in influenza virus-infected mice increased survival after pneumococcal superinfection
K Reppe, P Radünzel, K Dietert, T Tschernig, T Wolff… – Infection and Immunity, 2015
… Five days after IAV infection, 114 the mice were anesthetized intraperitoneally
(ip) with ketamine (80 mg/kg, Ketavet®, Pfizer, 115 … re-suspended in sterile PBS.
Mice were anesthetized ip with ketamine and xylazine and 123 …
Atorvastatin along with imipenem attenuates acute lung injury in sepsis through decrease in inflammatory mediators and bacterial load
S Choudhury, K Kannan, BS Maruti, MP Addison… – European Journal of …, 2015
… ad libitum. The animals were anesthetized by injection of xylazine (10 µg/g body
weight, intraperitoneally) and ketamine (80 µg/g body weight, intraperitoneally) and
a 2-cm ventral midline incision was performed. The cecum …
[HTML] Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase
YJ Lai, GJ Chang, YH Yeh, JHS Pang, CC Huang… – PLOS ONE, 2015
… All the surgery was performed under ketamine and xylazine ip anesthesia, and all efforts were
made to minimize suffering. Housing and maintenance was provided by Chang Gung University,
All animals were fed a standard chow diet with free access to water. …
[HTML] Serotonin 5-HT 7 receptor agonist, LP-211, exacerbates Na+, K+-ATPase/Mg 2+-ATPase imbalances in spinal cord-injured male rats
A Norouzi-Javidan, J Javanbakht, F Barati, N Fakhraei… – Diagnostic Pathology, 2015
… Animals were anesthetized by intraperitoneal injection of a mixture of ketamine hydrochloride
(75 mg/kg) and xylazine hydrochloride (5 mg/kg). … All animals were anesthetized (ketamine
hydrochloride 10 % + xylazine 2 %, in 80 and 5 mg/kg doses, respectively). …
[HTML] Interleukin-17A and Neutrophils in a Murine Model of Bird-Related Hypersensitivity Pneumonitis
M Ishizuka, Y Miyazaki, M Masuo, K Suhara, T Tateishi… – PLOS ONE, 2015
… They were then placed under light anesthesia with 100 mg/kg ketamine and 10 mg/kg xylazine,
and 5 μg of PDE in 25 μl of 0.9% saline was sprayed into each mouse’s trachea using an
intratracheal MycroSprayer® aerosolizer (Penn-century, Wyndmoor, PA, USA). …
Pertussis toxin reduces calcium influx to protect ischemic stroke in a middle cerebral artery occlusion model
Z Tang, S Li, P Han, J Yin, Y Gan, Q Liu, J Wang… – Journal of Neurochemistry, 2015
… blinded to the randomization. Permanent Middle Cerebral Artery Occlusion (pMCAO) Mice were
under Ketamine/Xylazine anesthesia (80 mg/kg Ketamine and 10mg/kg Xylazine, injected ip).
Standard aseptic surgical procedures were used throughout the procedure. The …
Radiofrequency Ablation (RFA)
Effectiveness and safety of computed tomography-guided radiofrequency ablation of renal cancer: a 14-year single institution experience in 203 patients
JD Iannuccilli, DE Dupuy, MD Beland, JT Machan… – European Radiology, 2015
Objectives To define effectiveness and safety of CT-guided radiofrequency ablation (RFA) of
renal tumours and prognostic indicators for treatment success. Methods Patients with a
single treatment of a solitary, biopsy-proven renal tumour with intent to cure over a 14-year …
Outcomes associated with ablation compared to combined ablation and transilluminated powered phlebectomy in the treatment of venous varicosities.
AT Obi, BN Reames, TJ Rook, SO Mouch, A Zarinsefat… – Phlebology/Venous Forum …, 2015
… RESULT: Venous clinical severity scores improved more with radiofrequency ablation +
transilluminated powered phlebectomy as compared to radiofrequency ablation alone
(3.8 ± 3.4 vs. 3.2 ± 3.1, p = 0.018). … radiofrequency ablation alone. …
Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations
S Mercadante, P Klepstad, G Paula Kurita, P Sjøgren… – Acta Oncologica, 2015
… Radiofrequency ablation (RFA). … RFA resulted more effective than radiotherapy and surgical
stabilization [99. Di Francesco A, Flamini S, Zugaro L, Zoccali C. Preoperative
radiofrequency ablation in painful osteolytic long bone metastases. …
[HTML] Efficiency and safety of radiofrequency-assisted hepatectomy for hepatocellular carcinoma with cirrhosis: A single-center retrospective cohort study
F Zhang, J Yan, XB Feng, F Xia, XW Li, KS Ma, P Bie – World J Gastroenterol, 2015
… These procedures include liver transplantation, resection, and radiofrequency ablation[ 5 ]. Liver
transplantation may be the best treatment option for cirrhotic patients with HCC because it involves
the simultaneous removal of both the cirrhotic liver and HCC[ 6 ]. However, the …
Ethanol ablation in post-biopsy liver hemorrhage following two failed Embolizations
MC Pope, DH Ballard, AL Sticker, C Ahuja… – Clinical Imaging, 2015
… C. The feeding vessels were identified and ablated with an additional 10 mL ethanol injection. …
to ultrasound-guided percutaneous ethanol injection for achieving hemostasis include techniques
such as cryoablation, radiofrequency (RF)-ablation, and cyanoacrylate glue …
[PDF] Catheter Ablation of Fascicular Ventricular Tachycardia: Long Term Clinical Outcomes and Mechanisms of Recurrence
Y Liu, Z Fang, B Yang, P Kojodjojo, H Chen, W Ju… – Circulation: Arrhythmia and …, 2015
… ablated. … Arrhythmia recurrences after an initially successful ablation were caused by recurrent
FVT involving the … Key words: ventricular tachycardia, radiofrequency, idiopathic left ventricular
tachycardia, fascicular ventricular tachycardia, outcomes, radiofrequency ablation …
Liver metastases from adenocarcinomas of unknown primary site: management and prognosis in 68 consecutive patients
E Algin, A Ozet, O Gumusay, G Yilmaz, S Buyukberber… – Wiener klinische …, 2015
… shown in Fig. 1. Among 39 patients who were managed with chemo- therapy, 12
patients received additional locoregional therapies including radiofrequency ablation
or transar- terial chemoembolization. Median OS was 9.4 …
[HTML] The Prognostic Value of Platelet Count in Patients With Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Q Pang, K Qu, JY Zhang, SD Song, SS Liu, MH Tai… – Medicine, 2015
… Abbreviations: HBV = hepatitis B virus, HCC = hepatocellular carcinoma, HCV = hepatitis C virus,
HR = hazard ratio, MPV = mean platelet volume, OS = overall survival, PLT = platelet count, RFA =
radiofrequency ablation, RFS = recurrence-free survival, TACE = transcatheter …
Safety and Feasibility of Open Chest Epicardial Mapping and Ablation of Ventricular Tachycardia During the Period of Left Ventricular Assist Device Implantation
M Patel, F Rojas, FR Shabari, L Simpson, W Cohn… – Journal of Cardiovascular …, 2015
… Endocardial and epicardial radiofrequency ablation of ventricular tachycardia associated with
dilated cardiomyopathy: The importance of low-voltage scars. … Comparison of epicardial
cryoablation and irrigated radiofrequency ablation in a swine infarct model. …
Contact Force Variability during Catheter Ablation of Atrial Fibrillation: The Role of Atrial Rhythm and Ventricular Contractions: Co-Force AF Study
A Sarkozy, D Shah, J Saenen, J Sieira, T Phlips… – Circulation: Arrhythmia and …, 2015
… 3 Background Lesion formation by using radiofrequency (RF) current depends on the power
delivered, duration of energy application, temperature, tip size, and tip orientation. … given RF power1.
Irrigated tip ablation catheters capable of real-time CF measurement have …
[HTML] Pulmonary vein isolation using the visually guided laser balloon: a prospective, multicenter, and randomized comparison to standard radiofrequency ablation
SR Dukkipati, F Cuoco, I Kutinsky, A Aryana… – Journal of the American …, 2015
Background Balloon catheters have been designed to facilitate pulmonary vein (PV)
isolation in patients with paroxysmal atrial fibrillation (AF). The visually guided laser balloon
(VGLB) employs laser energy to ablate tissue under direct visual guidance. Objectives …
Optimal Temperature for Radiofrequency Ablation of Lumbar Medial Branches for Treatment of Facet‐Mediated Back Pain
S Costandi, M Garcia‐Jacques, T Dews, M Kot, K Wong… – Pain Practice, 2015
Background Radiofrequency ablation (RFA) of the medial branch nerves that innervate the
facet joints is a well-established treatment modality; however, studies to determine the
optimal radiofrequency ablation temperature are lacking. A wide range (70 to 90 C) has …
[HTML] Catheter Ablation of Atrial Fibrillation: Advent of Second-Generation Technologies
E Buch, K Shivkumar – Journal of the American College of Cardiology, 2015
… and wide-area isolation (5), with or without additional lesion sets targeting non-PV
foci (6) or modifying atrial substrate. All of these techniques initially used
point-by-point ablation with radiofrequency (RF) ablation catheters. …
[HTML] Computed tomography-guided percutaneous trephine removal of the nidus in osteoid osteoma patients: experience of a single center in Brazil
M Petrilli, AA Senerchia, AS Petrilli, HM Lederman… – Radiologia Brasileira, 2015
… Osteoid osteoma: CTguided percutaneous radiofrequency ablation and follow-up in 47 patients.
J Vasc Interv Radiol. 2001;12:717–722. … Peyser A, Applbaum Y, Khoury A, et al. Osteoid osteoma:
CT-guided radiofrequency ablation using a water-cooled probe. Ann Surg Oncol. …
Proton beam therapy for metastatic liver tumors
N Fukumitsu, T Okumura, D Takizawa, H Makishima… – Radiotherapy and Oncology, 2015
… The maximal diameter of the lesions was 1–18 cm (median, 4 cm). Of the 140 patients, 87
had received another form of treatment before PBT, such as chemotherapy, radiofrequency
ablation, transcatheter arterial chemoembolization, and surgery. …
Accuracy of Late Gadolinium Enhancement-Magnetic Resonance Imaging in the Measurement of Left Atrial Substrate Remodeling in Patients With Rheumatic Mitral …
D Zhu, Z Wu, RJ van der Geest, Y Luo, J Sun, J Jiang… – International Heart Journal, 2015
… We enrolled adult patients with rheumatic mitral valve disease and persistent AF who un-
derwent open-heart surgery for mitral valve replacement with concurrent radiofrequency
ablation for AF at our institution between February 2013 and March 2014. …
Predictive value of nodule size and differentiation in HCC recurrence after liver transplantation
GG Piero, P Domenico, F Di Benedetto, M Elena… – Surgical Oncology, 2015
… Generally, radiofrequency ablation (RFA) was proposed in cases of a single tumor less than 3
cm, whereas a single tumor > 3 cm or multifocal lesions in patients with impaired liver function
were directed instead to treatment with trans-arterial chemoembolization (TACE). …
Radiofrequency ablation or stripping of large-diameter incompetent great saphenous varicose veins with C2 or C3 disease
EV Shaidakov, AG Grigoryan, EA Ilyukhin, VL Bulatov… – Journal of Vascular Surgery: …, 2015
Objective The objectives of this study were to compare the results of radiofrequency ablation
(RFA) and stripping for large-diameter varicose target veins for the period of 1 year, based
on a composite end point; to analyze the pain severity on a digital rating scale for 7 days …
Clinical outcomes and risk factors of hepatocellular carcinoma treated by liver transplantation: A multi-centre comparison of living donor and deceased donor …
Z Hu, Z Qian, J Wu, J Zhou, M Zhang, L Zhou, S Zheng – Clinics and Research in …, 2015
… HCC: hepatocellular carcinoma; LDLT: living donor liver transplantation; DDLT: deceased donor
liver transplantation; GWRW: graft weight/recipient weight; TACE: transcatheter arterial
chemoembolisation; RFA: radiofrequency ablation; PEI: percutaneous ethanol injection; ICU …
[PDF] Hepatocellular carcinoma treatment strategies–a case-based review
R Alves, MT Gomes, CS Macedo, HP Miranda, F Nery – Journal of Solid Tumors, 2015
… Resection techniques have been refined, from the use of new radiofrequency ablation resection
devices to laparoscopic approaches, both showing to diminished blood loss [1, 2]. A recent
meta-analysis showed that laparoscopic approach decreases blood loss, transfusion …
Complex Regional Pain Syndrome (CRPS/RSD)
Skin sympathetic function in complex regional pain syndrome type 1
A Poudel, M Asahina, Y Fujinuma, Y Yamanaka… – Clinical Autonomic …, 2015
… 10.1007/s10286-015-0314-x. Copyright information. Abstract. Purpose. Cutaneous
sympathetic pathophysiology in complex regional pain syndrome type 1 (CRPS-1) is
not yet completely understood. To evaluate cutaneous sympathetic …
Substance P spinal signaling induces glial activation and nociceptive sensitization after fracture
WW Li, TZ Guo, X Shi, Y Sun, T Wei, DJ Clark… – Neuroscience, 2015
… hypersensitivity. Abstract. Tibia fracture in rodents induces substance P
(SP)-dependent keratinocyte activation and inflammatory changes in the hindlimb,
similar to those seen in complex regional pain syndrome (CRPS). In …
Economic impact of mgnregp on rural livelihood security in tumkur district, karnataka–a sam analysis
CHR Gowda – 2015
… Item Type: Thesis (Masters). Divisions: RP-Market Institutions and Policies. CRPS: CGIAR
Research Program on Policies, Institutions, and Markets. Uncontrolled Keywords: Economic
Impact, MGNREGP, Rural Livelihood Security, Karnataka, SAM analysis. …
[PDF] DMSA-coated Iron Oxide Nanoparticle Greatly Affect the Expression of Genes Coding Cysteine-rich Proteins by its DMSA Coating
L Zhang, X Wang, J Zou, Y Liu, J Wang – Chemical Research in Toxicology, 2015
… times. The results revealed that about one fourth of DEGs coded cysteine-rich proteins
(CRPs) in all cells under each treatment, indicating that the nanoparticles greatly
affected the expressions of CRP-coding genes. Additionally …
Changing appearance using visual illusions improves ownership of the painful hand in complex regional pain syndrome
J Lewis, C McCabe, R Newport – 2015
… Abstract. Background and aims People with Complex Regional Pain Syndrome (CRPS)
experience a diminished sense of ownership of their painful limb. … Thirty nine patients with CRPS
of one arm were randomly allocated to either a control or experimental group. …
The role of genetically‐engineered pigs in xenotransplantation research
DKC Cooper, B Ekser, J Ramsoondar, C Phelps… – The Journal of Pathology, 2015
… This is because of the expression of human complement-regulatory proteins (CRPs) on the
surface of vascular endothelial cells. Pigs have similar CRPs, but these are relatively inefficient
at protecting the pig cells from human complement-mediated injury [13]. …
Individuality: How knowledge of body perception disturbance can inform treatment
J Lewis – 2015
… Lewis, J. (2015) Individuality: How knowledge of body perception disturbance can inform
treatment. In: International Association of the Study of Pain (IASP) CRPS SIG, Zurich, Switzerland,
31 August – 1 September 2015. [img] Preview. PDF 1MB. Abstract. …
Spinal Cord Stimulation (SCS) and Functional Magnetic Resonance Imaging (fMRI): Modulation of Cortical Connectivity With Therapeutic SCS
M Deogaonkar, M Sharma, C Oluigbo, DM Nielson… – … : Technology at the Neural …, 2015
… Methods. Ten patients with complex regional pain syndrome (CRPS) or neuropathic leg pain
underwent thoracic epidural spinal cord stimulator implantation. Stimulation parameters associated
with “optimal” pain reduction were evaluated prior to imaging studies. …
[PDF] Similarity-based semi-local estimation of EMOS models
S Lerch, S Baran – arXiv preprint arXiv:1509.03521, 2015
… The most popular scoring rules providing summary measures of predictive performance are the
logarithmic score, ie, the negative logarithm of the predictive PDF evaluated at the verifying
observation, and the continuous ranked probability score (CRPS; Gneiting and Raftery …
Review of Plastic Surgery
DW Buck II – 2015
[PDF] Independent CRP-Commissioned External Evaluation of the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH)
J Compton, D McLean, B Emmens, M Balagamwala – 2015
… development partners (IFPRI, 2011). CRPs are not legal entities and therefore legal
and financial responsibility for A4NH ultimately rests with the lead CGIAR Center
and its Board of Trustees (IFPRI- BOT). 2. IFPRI is legally …
[PDF] Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis
C Compagnone, F Tagliaferri – Acta Bio Medica Atenei Parmensis, 2015
… Different diseases could lead to neuro- pathic pain including postsurgical pain, post-herpetic
neuralgia (PHN), spinal cord stenosis (SCS), Complex Regional Pain Syndrome (CRPS), Diabetic
peripheral neuropathy (DPN), and chemotherapy induced pe- ripheral neuropathy. …
Traumatic Life Events and Psychopathology in a High Risk, Ethnically Diverse Sample of Young Children: A Person-Centered Approach
MJ Hagan, MJ Sulik, AF Lieberman – Journal of abnormal child psychology, 2015
… Conditional response probabilities (CRPs) are defined as the probability that an
individual from a specific latent class will endorse an item. CRPs provide … across
classes. CRPs for the exploratory LCA model are shown in Fig. …
Two placebo-controlled, randomized withdrawal studies to evaluate the fentanyl 1-day patch in opioid-naïve patients with chronic pain
T Arai, Y Kashimoto, Y Ukyo, Y Tominaga, K Imanaka – Current Medical Research …, 2015
… study]) and the other study included opioid-naïve subjects with neuropathic pain (post- herpetic
neuralgia, complex regional pain syndrome [CRPS], or chronic postoperative pain; … included: had
osteoarthritis, low back pain, post-herpetic neuralgia, CRPS, or chronic …
[PDF] Challenges of Peripheral Nerve Stimulator Implantation in a Patient with New Onset Thrombocytopenia
S Thompson
… We present a patient with complex regional pain syndrome (CRPS)-like symptoms of the lateral
femoral cutaneous nerve after laparoscopic hysterectomy who underwent successful
ultrasound-guided PNS trial using SCS leads and unfortunate delayed implantation due to …
Improving student learning via mobile phone video content: Evidence from the BridgeIT India project
M Wennersten, ZB Quraishy, M Velamuri – International Review of Education
[PDF] The Association Between Soft Tissue Releases and Bony Resections Performed During Total Knee Arthroplasty and Patients’ Pain and Satisfaction Postoperatively
M Carter – 2015
Page 1. Western University Scholarship@Western Electronic Thesis and Dissertation Repository
September 2015 The Association Between Soft Tissue Releases and Bony Resections Performed
During Total Knee Arthroplasty and Patients’ Pain and Satisfaction …
[PDF] Parthasarathy Rao and Cynthia Bantilan. 2015. Grain Legumes Production, Consumption and Trade Trends in Developing Countries
S Nedumaran, P Abinaya, P Jyosthnaa, B Shraavya
… Markets (PIM). Financial support by CRPs Grain Legumes and Policies, Institutions
and Markets are gratefully acknowledged. This working paper has gone through
the standard peer-review procedure of ICRISAT. The authors …
NEUROMODULATORY DEVICES, SYSTEMS, AND METHODS FOR TREATING FIBROMYALGIA
AR Rezai, M Deogaonkar – US Patent 20,150,251,008, 2015
… In subjects with fibromyalgia as well as other conditions (eg, hot flashes, CRPS, etc.),
clinicians have used pharmacological blockade of the sympathetic nervous system, and
in particular the stellate ganglion, to achieve some clinical benefit. …
Fibromyalgia
Psychiatric Disorders in Young Adults Diagnosed with Juvenile Fibromyalgia in Adolescence.
NR Cunningham, ST Tran, AM Lynch-Jordan, TV Ting… – The Journal of …, 2015
OBJECTIVE: Adolescents with juvenile-onset fibromyalgia (JFM) have increased rates of
psychiatric disorders, but to our knowledge no studies have examined psychiatric disorders
in adolescents with JFM when they enter young adulthood. This study examined the …
Fibromyalgia beyond reductionism. Heart rhythm fractal analysis to assess autonomic nervous system resilience
C Lerma, LA Martinez-Martinez, N Ruiz, A Vargas… – Scandinavian Journal of …, 2015
Objectives: The prevailing linear reductionist medical model seems unable to explain
complex multisymptomatic illnesses such as fibromyalgia (FM) and similar maladies.
Paradigms derived from the complexity theory may provide a coherent framework for …
Exploring the role of peripheral mechanisms: An evaluation of a theory-based approach to reducing symptoms of fibromyalgia
K Mooney – 2015
Abstract: This mixed method study presented an integrative approach for the treatment of
fibromyalgia, the rationale that justifies the approach, and an evaluation of two integrated
components of this protocol designed to mitigate symptoms of fibromyalgia. Considering …
Chronic Widespread Back Pain is Distinct from Chronic Local Back Pain: Evidence from Quantitative Sensory Testing, Pain Drawings, and Psychometrics.
A Gerhardt, W Eich, S Janke, S Leisner, RD Treede… – The Clinical journal of pain, 2015
… Therefore, this study compared quantitative-sensory-testing (QST) profiles of
non-specific chronic back pain patients with CLP (n=48) and CWP (n=29) with
pain-free controls (PCs, n=40) and Fibromyalgia patients (FMS, n=90). …
Meta-analytic evidence for decreased heart rate variability in chronic pain implicating parasympathetic nervous system dysregulation.
LM Tracy, L Ioannou, KS Baker, SJ Gibson… – PAIN, 2015
… frequency HRV in chronic pain, implicating a decrease in parasympathetic activation.
These effects were heavily influenced by fibromyalgia studies. Future research would
benefit from wider use of standardised definitions of …
[HTML] Analgesic effect of cathodal transcranial current stimulation over right dorsolateral prefrontal cortex in subjects with muscular temporomandibular disorders: study …
RA Brandão Filho, AF Baptista, RAFS Brandão… – Trials, 2015
… In a fibromyalgia study using transcranial magnetic stimulation (TMS), the authors found higher
thresholds in both sides of the resting motor cortex with lower up regulation responses.
Furthermore, they found lower intracortical facilitation and inhibition. …
Clinical Research Methodology 1: Study Designs and Methodologic Sources of Error
DI Sessler, PB Imrey – Anesthesia & Analgesia, 2015
… The distinction can be nonobvious. For example, consider a study in which investigators compared
anesthetic requirement in patients with and without fibromyalgia. … But, in fact, fibromyalgia is the
exposure in this study and anesthetic requirement is the outcome. …
[HTML] Economic evaluation in chronic pain: a systematic review and de novo flexible economic model
W Sullivan, M Hirst, S Beard, D Gladwell, F Fagnani… – The European Journal of …, 2015
… While the attributes and management of specific diseases associated with chronic pain, such
as fibromyalgia and osteoarthritis, and different analgesic requirements for neuropathic versus
other chronic pain may have justifiably led to modelling heterogeneity, clinical …
[PDF] Evaluation of the Immediate Effect of Auricular Acupuncture on Pain and Electromyographic Activity of the Upper Trapezius Muscle in Patients with Nonspecific Neck …
ACO Silva, DA Biasotto-Gonzalez, DM Santos… – … -Based Complementary and …, 2015
… NS-NP could contribute to the following: (i) a standardization of the points to be used as stimuli
for the treatment of abnormalities caused in this muscle by mechanical injuries, myofacial tension
(with or without trigger-points), and systemic diseases such as fibromyalgia; (ii) an …
Ehlers Danlos syndrome and gastrointestinal manifestations: a 20‐year experience at Mayo Clinic
AD Nelson, MA Mouchli, N Valentin, D Deyle… – Neurogastroenterology & …, 2015
… hernia,[7] rectal evacuation disorder,[8] diverticulosis, gastritis,[9] constipation, diarrhea, nausea,
vomiting, abdominal pain, and reflux disease.[10] Several non-musculoskeletal symptoms often
found in patients with functional GI disorders such as fibromyalgia, fatigue, cognitive …
[HTML] Real-life assessment of the validity of patient global impression of change in fibromyalgia
E Rampakakis, PA Ste-Marie, JS Sampalis, A Karellis… – RMD Open, 2015
Objectives Patient Global Rating of Change (GRC) scales are commonly used in routine
clinical care given their ease of use, availability and short completion time. This analysis
aimed at assessing the validity of Patient Global Impression of Change (PGIC), a GRC …
[HTML] Increased Risk of Coronary Heart Disease in Patients with Primary Fibromyalgia and Those with Concomitant Comorbidity—A Taiwanese Population-Based Cohort …
CH Su, JH Chen, JL Lan, YC Wang, CH Tseng, CY Hsu… – PLOS ONE, 2015
Objectives Fibromyalgia has seldom been associated with coronary heart disease (CHD).
The aim of this study was to evaluate the risk of CHD in patients with fibromyalgia. Methods
We used a dataset of one million participants, systemically scrambled from the Taiwanese …
[HTML] Group cognitive-behavioral therapy for chronic pain adults: review of Brazilian trials
LF Kirchner, CC Jorge, MJD Reis – Revista Dor, 2015
… 26 . With regard to studied population, table 1 shows predominance of females in all studies,
being fibromyalgia (FM) the most frequent diagnosis. Nevertheless, literature … assertiveness,
3. (6 to 8), Fibromyalgia (100%), VAS. LSSI. RAS. Lorençatto …
[HTML] Chronic Pain Pharmacological Treatment in Patients with Depressive Disorders
C Aurilio, MC Pace, MB Passavanti, V Pota, P Sansone… – Journal of Psychiatry, 2015
… Patients with fibromyalgia present a reduced dopamine presynaptic activity in great many
brain regions, included hippocampus. Neurocircuits and neurochemistry. … [50] published
a review on amitriptyline for neuropathic pain and fibromyalgia. …
Medical Marijuana Patient Counseling Points for Healthcare Professionals Based on Trends in the Medical Uses, Efficacy, and Adverse Effects of Cannabis-Based …
JR Parmar, BD Forrest, RA Freeman – Research in Social and Administrative …, 2015
… All three medications have similarly been used in improving sleep, fibromyalgia, rheumatoid
arthritis associated pain, and spasticity in MS. A complete list of medical uses and included
publications can be reviewed in Table 5. Table 5. … Fibromyalgia, 1 16, 16, …
Identification and description of controlled clinical trials published in Physiotherapy journals in Spain
M Turrillas, M Sitjà‐Rabert, H Pardo… – Journal of Evaluation in …, 2015
… 16.7% of the identified studies were multicentric. Traumatology and orthopaedics was the most
studied field (33.3%) followed by neurology (15.4%). The most researched health problems were
back pain (17.24%) fibromyalgia, arthrosis and stroke (6.8% each). …
[HTML] Serum calprotectin (S100A8/9): an independent predictor of ultrasound synovitis in patients with rheumatoid arthritis
J Hurnakova, J Zavada, P Hanova, H Hulejova, M Klein… – Arthritis Research & …, 2015
… which is obtained by using several composite indexes [4–7]. Nevertheless, a clinical examination
might lack sensitivity in patients with mild synovitis, be limited in patients with established
deformities, and be overestimated in patients with concomitant fibromyalgia or other …
[HTML] Systematic review of the measurement properties of self-report physical activity questionnaires in healthy adult populations
Z Silsbury, R Goldsmith, A Rushton – BMJ Open, 2015
… 6 The review found strong evidence for effectiveness within cardiovascular disease, type 2
diabetes and obesity; and strong evidence for improved symptom management and quality of
life for patients with cancer, osteoarthritis, osteoporosis, fibromyalgia and depression. …
[PDF] Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis
C Compagnone, F Tagliaferri – Acta Bio Medica Atenei Parmensis, 2015
… JOP 2003; 4 (1): 1-10. 4. Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Ami- triptyline for
neuropathic pain and fibromyalgia in adults. … Review. 5. Moore RA, Wiffen PJ, Derry S, Toelle
T, Rice AS. Gabapen- tin for chronic neuropathic pain and fibromyalgia in adults. …
Illness deception
SB Nimmo – Occupational Medicine, 2015
… In a survey of US neuropsychologists, prevalence of malingering and symptom exaggeration
was found to be minor head injury 39%, fibromyalgia/chronic fatigue syndrome 35%, chronic
pain 31%, personal injury cases 29%, disability or workers compensation 30% and …
by admin | Aug 13, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
[HTML] Which Sedation is more Appropriate during Spinal Anesthesia: Propofol or Ketamine-Propofol Combination
H Güleç, ZB Tutal, M Şahap, M Babayiğit, H İnceöz… – Anaesth Pain & Intensive …, 2015
ABSTRACT Background and objective: Spinal anesthesia is a preferred method in daily
practice as it provides muscle relaxation and maintains spontaneous respiration during
surgical procedures. Opiods, midazolam, ketamine, propofol and dexmedetomidine are …
[PDF] Evaluation of Use of Ketamine Hydrochloride for Induction of Anaesthesia in Rabbits with Experimentally Induced Unilateral Ureteral Obstruction
RI Udegbunam, KC Ogbanya, SO Udegbunam… – 2015
ABSTRACT This study investigated the anaesthetic characteristics of ketamine
hydrochloride in rabbits with Unilateral Ureteral Obstruction (UUO). Two groups of rabbits (B
and C) were anaesthetized with 30 mg kgG1 ketamine intravenously (IV) on days 7 and …
Case 62: What Are the Safety Data for This Formulation?
JG Brock-Utne – Clinical Research, 2015
… Discussion We were faced with this problem when we wanted to use ketamine intrathecally. …
References 1. Brock-Utne JG, Mankowitz E, Kallichurum S, Downing JW. Effects of intrathecal
saline and ketamine with or without preservatives on the spinal nerve roots of monkeys. …
[HTML] Ligands Binding to Cell Surface Ganglioside GD2 Cause Src-Dependent Activation of N-Methyl-D-Aspartate Receptor Signaling and Changes in Cellular Morphology
W Tong, M Maira, M Gagnon, HU Saragovi – PLOS ONE, 2015
… For pharmacological inhibition, the Src kinase inhibitor PP2 (20 μM) (Enzo Life Science),
NMDA-R antagonist ketamine (Bioniche Animal Health) (20 μM) or the PKA inhibitor H-89 (Sigma)
(20 ng/ml) were added to the resting cells 30 minutes before the indicated treatments. …
[PDF] Development of Certified Reference Materials of Drug Abuse (Heroin, Etc) for Elimination of Measurement Error in Forensic Drugs
F Su, X Dai, H Li – Pharm Anal Acta, 2015
… For the first time, we developed 9 illicit drug CRMs, including methamphetamine, heroin,
ketamine and others. … CRMs Column Mobile phase Acetonitrile:water Flow Rate (mL/min)
Injection volume(uL) DAD (nm) Ketamine hydrochloride a 40:60* 1.5 20 210 …
[HTML] AdHu5Ag85A Respiratory Mucosal Boost Immunization Enhances Protection against Pulmonary Tuberculosis in BCG-Primed Non-Human Primates
M Jeyanathan, Z Shao, X Yu, R Harkness, R Jiang, J Li… – PLOS ONE, 2015
… Animals were euthanized first by anesthesia with ketamine (im 10 mg/kg) and then by a lethal
dose injection of sodium pentobarbital (iv 100 mg/kg). Experimental animals and handling. …
Animals were anesthetized with ketamine (10 mg/kg) before handling. …
The relative contribution of urine extravasation to elevate plasma creatinine levels in acute unilateral ureteral obstruction.
ME Chua, J Mendoza, IV See, E Esmena, D Aguila… – Canadian Urological …, 2015
… Under sedation with isoflurane inhalation, all rats were subsequently anesthetized with
intraperitoneal (IP) ketamine (100 mg/kg) plus xylazine (15 mg/kg) after being preopera- tively
hydrated by subcutaneous injection of 5 cc saline mixed with indigo carmine (5,5 …
P-193TRACHEAL RESECTION WITH PATIENT UNDER LOCAL ANAESTHESIA AND SEDATION
FP Caronia, D Loizzi, A Fiorelli – Interactive CardioVascular and Thoracic Surgery, 2015
… During the procedure the patient remained awake in conscious sedation achieved by bolus
of ketamine and midazolam. … During the entire procedure the patient remained awake in
conscious sedation achieved by bolus of ketamine and midazolam. …
[HTML] Neural Resolution of Formant Frequencies in the Primary Auditory Cortex of Rats
C Honey, J Schnupp – PLOS ONE, 2015
… Anesthesia was induced by intraperitoneal injection of ketamine (Ketaset; Fort Dodge Animal
Health, Overland Park, Kansas, USA) and medetomidine (Domitor, Pfizer, Walton Oaks, Surrey,
UK), and maintained with intraperitoneal infusions of ketamine, medetomidine and …
Aerobic training normalizes autonomic dysfunction, HMGB1 content, microglia activation and inflammation in hypothalamic paraventricular nucleus of SHR
GS Masson, AR Nair, PPS Soares, LC Michelini… – American Journal of …, 2015
… Analysis of Cardiovascular Parameters and Baroreflex Function 135 At the end of the protocols,
rats were anaesthetized (ketamine, 80 mg.kg−1 plus 136 … calculated as BrS = –(P2×P3)/4. 152
After the physiologic measurements, animals were anesthetized (ketamine, 80 153 …
Combination of intravenous S-ketamine and oral tranylcypromine in treatment-resistant depression: A case report
L Bartova, SE Vogl, M Stamenkovic… – European …, 2015
Abstract Ketamine, a rapid-acting antidepressant and anti-suicidal agent, is thought to
increase brain monoamine levels by enhancing monoamine release or inhibiting
presynaptic monoamine-reuptake. Here we present two female inpatients suffering from …
Ketamine Abuse Syndrome: Hepatobiliary and Urinary Pathology Among Adolescents in Flushing, NY.
JW Wang, V Kivovich, L Gordon – Pediatric Emergency Care, 2015
Objectives: Ketamine is a recreational drug widely abused in East Asia and also in certain
subpopulations of the United States. Many US clinicians are unaware of abuse symptoms,
leading to misdiagnosis and missed opportunities for intervention. We will discuss clinical …
Ketamine Abuse Syndrome
JW Wang, V Kivovich, L Gordon – 2015
Objectives: Ketamine is a recreational drug widely abused in East Asia and also in certain
subpopulations of the United States. Many US clinicians are unaware of abuse symptoms,
leading to misdiagnosis and missed opportunities for intervention. We will discuss clinical …
Ondasetron Is More Likely Than Ketamine to Cause Ventricular Tachycardia
P Marzuillo, I Rabach, E Barbi – Pediatric Emergency Care, 2015
We read with interest the article published in the October 2014 issue of Pediatric Emergency
Care entitled “Ventricular tachycardia after ketamine sedation for fracture reduction.” Stukus
et al 1 described a 10-year-old female patient who experienced asymptomatic ventricular …
The development of paper microfluidic devices for presumptive drug detection.
G Musile, L Wang, J Bottoms, F Tagliaro, B McCord – Analytical Methods, 2015
… different lanes. A different colorimetric reaction occurs within each lane, permitting
the multiplexed detection of a variety of different compounds, including cocaine,
opiates, ketamine, and various phenethyl amines. Furthermore …
[PDF] GLP-1 increases pre-ovulatory LH source and the number of mature follicles, as well as synchronizing the onset of puberty in female rats
V Outeiriño-Iglesias, M Romaní-Pérez… – Endocrinology, 2015
… bregma. Cannulation was performed under ketamine/xylazine anesthesia (50
mg/kg and 5 mg/kg, respectively) and the correct placement of the cannula was
confirmed by postmortem injection of trypan- blue 0.5% (Sigma, St. …
[HTML] Bispectral index-guided induction of anesthesia by ketofol infusion provides the same cardiovascular stability like that of etomidate infusion
HF Soliman – Ain-Shams Journal of Anaesthesiology, 2015
… Get Permissions. Abstract, Introduction Various techniques have been tried to maintain
cardiovascular stability with anesthesia induction. This study compares the cardiovascular effects
of propofol-ketamine mixture versus etomidate during the induction of anesthesia. …
[PDF] Anti-osteoporotic activity of ethanol extract of Terminalia arjuna (Roxb.) Wight & Arn. on ovariectomized rats
A Trivedi, HR Katti, MH Shalavadi, A Ramkishan… – Indian Journal of Natural …, 2015
… Estrogen and Ketamine obtained from Neon Laboratories Ltd. Mumbai, India. … After seven days
of acclimation, the rats were ovariectomized or Sham operated and then anesthetized with
Ketamine HCL (50 mg/kg, ip); the ovaries were removed bilaterally. …
[HTML] Long-Term Extensive Ectopic Hair Growth on the Spinal Cord of Mice from Transplanted Whisker Follicles
W Cao, L Li, S Mii, Y Amoh, F Liu, RM Hoffman – PloS one, 2015
… Animals were anesthetized by intramuscular injection of a 0.02 ml solution of 20 mg/kg
ketamine, 15.2 mg/kg xylazine, and 0.48 mg/kg acepromazine maleate. … Non-transgenic nude
mice were anesthetized with a ketamine mixture (described above). …
Retinal functional alterations in mice lacking intermediate filament proteins glial fibrillary acidic protein and vimentin
KA Wunderlich, N Tanimoto, A Grosche, E Zrenner… – The FASEB Journal, 2015
… Mice were dark- adapted (DA) overnight before the experiments and anesthetized with a
subcutaneous injection of a mixture of ketamine, xylazine, and physiologic saline. Ketamine
and xylazine were given at 66.7 and 11.7 mg/kg body weight, respectively. …
Radiofrequency Ablation (RFA)
[PDF] Electrophysiological Bases of Torsion and Suction in the Continuous Cardiac Band Model
J Trainini, B Elencwajg, N López-Cabanillas… – Anat Physiol, 2015
… early diastolic filling by the suction effect. We investigated the electrophysiological
basis of this mechanism, by electroanatomical left ventricular endoepicardial mapping
(EEM) in five patients, during radiofrequency ablation. …
Uninterrupted Apixaban Safe and Effective in AF Ablation
EH Nichols – MD Conference Express, 2015
… Summary. According to a multicenter, prospective registry study, uninterrupted apixaban used
in the periprocedural setting of radiofrequency catheter ablation in patients with atrial fibrillation
does not increase the risk of bleeding compared with uninterrupted warfarin. …
Lateral Femoral Cutaneous Nerve Block
P Tumber, PWH Peng – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… Pain Pract. 2011;11(3):302–8.PubMedView Article; 15. Fowler IM, Tucker AA, Mendez RJ.
Treatment of meralgia paresthetica with ultrasound-guided pulsed radiofrequency ablation of
the lateral femoral cutaneous nerve. Pain Pract. 2012;12(5):394–8.PubMedView Article. …
Sacroiliac Joint
PWH Peng – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… Am J Phys Med Rehabil. 2006;85:997–1006.PubMedView Article; 6. Roberts S, Burnham R,
Ravichandiran K, Agur A, Loh E. Cadaveric study of sacroiliac joint innervation: implications
for diagnostic blocks and radiofrequency ablation. Reg Anesth Pain Med. …
Ilioinguinal, Iliohypogastric, and Genitofemoral Nerve Blocks
D Bugada, PWH Peng – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… 2014;2014:371703. doi:10. 1155/ 2014/ 371703.PubMed CentralPubMed; 47. Terkawi AS,
Romdhane K. Ultrasound-guided pulsed radiofrequency ablation of the genital branch of the
genitofemoral nerve for treatment of intractable orchalgia. Saudi J Anaesth. …
[HTML] Neoplastic disease after liver transplantation: focus on de novo neoplasms
P Burra, KI Rodríguez-Castro – World J Gastroenterol, 2015
… Prognosis seems dismal according to reported cases, despite tapering of
immunosuppression, transarterial chemoembolization, radiofrequency ablation, hepatic
resection, or retransplantation. Strategies for preventing this neoplasm …
Pediatric Nuclear Medicine
PJ Koo, FD Grant – Nuclear Medicine and PET/CT Cases, 2015
European Heart Rhythm Society, EHRA EUROPACE-CARDIOSTIM2015
RP Giugliano, S Bansilal, MP Bonaca, M Cavender… – MD Conference Express, 2015
… Two registry studies examined the use of non–vitamin K antagonist oral anticoagulant
use in patients with atrial fibrillation (AF) undergoing radiofrequency catheter ablation
(RFA). The first determined that AF patients can safely …
[HTML] Propensity Score Matching Analysis of Changes in Alpha-Fetoprotein Levels after Combined Radiotherapy and Transarterial Chemoembolization for Hepatocellular …
Y Jeong, SM Yoon, S Han, JH Shim, KM Kim, YS Lim… – PLOS ONE, 2015
Advertisement. …
Iron Oxide Based Nanoparticles for Multimodal Imaging and Magnetoresponsive Therapy
N Lee, D Yoo, D Ling, MH Cho, T Hyeon, J Cheon – Chemical Reviews, 2015
… When a resonant radiofrequency is irradiated, the nucleus absorbs the energy and the
number of the spins with a higher-energy state increases. … During the relaxation process,
the excited nuclei emit a weak radiofrequency that can be detected. …
… Radiofrequency Ablation: Comparison of Transarterial Chemoembolization Alone and Combined Therapy with Transarterial Chemoembolization and Radiofrequency …
D Hyun, SK Cho, SW Shin, KB Park, HS Park… – CardioVascular and …, 2015
Purpose To report the results of combined therapy with transarterial chemoembolization
(TACE) and radiofrequency ablation (RFA) for early stage hepatocellular carcinoma (HCC)
considered infeasible for ultrasound (US)-guided RFA in comparison with those of TACE …
The procedure outcome of laparoscopic resection for’small’hepatocellular carcinoma is comparable to vlaparoscopic radiofrequency ablation
M Casaccia, G Santori, G Bottino, P Diviacco… – 2015
Background: The aim of this study was to compare the effectiveness of laparoscopic liver
resection (LLR) and laparoscopic radiofrequency ablation (LRFA) in the treatment of small
nodular hepatocellular carcinoma (HCC). Patients And Methods: We enrolled 50 cirrhotic …
PTH-177 Radiofrequency ablation for complicated barrett’s oesophagus: experience of a tertiary centre in northern ireland at 5 years
P Hall, O Reed, I Mainie – Gut, 2015
Abstract Introduction The 2013 British Society of Gastroenterology (BSG) guideline supports
first line use of endoscopic therapy in patients with dysplastic Barrett’s oesophagus or
intramucosal carcinoma (IMC). 1 Endoscopic mucosal resection (EMR) and …
Observations on Attenuation of Local Electrogram Amplitude and Circuit Impedance During Atrial Radiofrequency Ablation: An In vivo Investigation Using a Novel …
A Bhaskaran, W Chik, C Nalliah, J Pouliopoulos… – Journal of Cardiovascular …, 2015
Aims To define the temporal characteristics of atrial lesion growth (lesion surface area), local
electrogram amplitude attenuation and circuit impedance decrement during in vivo Radio
Frequency (RF) ablation with direct endocardial visualization (DEV).
[HTML] Intraductal Radiofrequency Ablation Followed by Locoregional Tumor Treatments for Treating Occluded Biliary Stents in Non-Resectable Malignant Biliary Obstruction …
XH Duan, YL Wang, XW Han, JZ Ren, TF Li, JH Zhang… – PloS one, 2015
Objectives To determine the safety and feasibility of intraductal radiofrequency ablation
(RFA) followed by locoregional tumor treatments in patients with non-resectable malignant
biliary obstruction and stent re-occlusion. Methods Fourteen patients with malignant biliary …
Sorafenib combined with radiofrequency ablation in the treatment of a patient with renal cell carcinoma plus primary hepatocellular carcinoma
G Gang, Y Hongkai, Z Xu – 2015
The combination of renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC) is
extremely rare, and the prognosis for patients with these two cancers is poor. In the past
decade, molecular targeted therapy and radiofrequency ablation (RFA) have emerged …
RADIOFREQUENCY ABLATION FOR BENIGN THYROID NODULES-A LOOK TOWARDS THE FUTURE OF INTERVENTIONAL THYROIDOLOGY
MA Lupo – Endocrine Practice, 2015
Welcome to the new Endocrine Practice website. Click HERE to access your account and reset
your password if this is your first visit. The IP ranges for your institution have already been added
to your account. You may wish to review this information under the Institutional …
[PDF] Clinical Effect of Percutaneous Radiofrequency Ablation for Residual Lung Metastases from Breast Cancer After Systemic Chemotherapy
Y Wang, X Lu, Y Wang, J Zhou – Journal of the College of Physicians and Surgeons …, 2015
Breast Cancer (BC) is the most common malignant tumor in women and it is the leading cause
of death in women.1 The earliest and most frequent site of BC metastasis is the lungs and
bones, and no more than 5 – 20% of cases have only liver metastases.2 Metastatic BC …
Recanalization of obstructed metallic uncovered biliary stent using endobiliary radiofrequency ablation
N Musquer, E Ménager Tabourel, D Luet… – Gastrointestinal Endoscopy, 2015
We present the case of a 57-year-old woman with a history of hilar cholangiocarcinoma type
3A of the Bismuth classification. A right hepatectomy after right portal embolization was
planned. Finally, because peritoneal carcinomatosis was diagnosed during surgery, a …
Ventricular premature depolarization ablation and reversal of nonischemic cardiomyopathy
RC Arroyo, S Maeda, BP Betensky, P Santangeli, D Lin… – Interventional Cardiology, 2015
… 4.4 cm. CM: Cardiomyopathy; LVDD: Left ventricular end-diastolic dimension; LVEF:
Left ventricular ejection fraction; RFA: Radiofrequency ablation; VPD: Ventricular
premature depolarization. Ventricular premature depolarization …
Complex Regional Pain Syndrome (CRPS/RSD)
Lumbar Plexus and Femoral Nerve Block. Traditional and Ultrasound Guided Techniques
D Jankovic, J Kessler, AT Gray – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… 5. Arterial occlusive disease and poor perfusion in the lower extremities. 6. Complex regional
pain syndrome (CRPS) types I and II. 7. Postamputation pain. 8. … 3. Prophylaxis against complex
regional pain syndrome (CRPS). Contraindications. Specific. 1. …
Superior Cervical Ganglion Block
D Jankovic – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… Therapeutic [ 3 ]. 1. Migraine [ 4 ], cluster headache, and headaches of cervical origin. 2. Complex
regional pain syndrome (CRPS) in the head region. 3. Perfusion disturbances and vasospastic
diseases. 4. Central poststroke syndrome (contralateral block!). 5. Facial pain. 6. …
Brachial Plexus Blocks Above the Clavicle Traditional Techniques
D Jankovic – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… 10–20 mL local anesthetic – eg, 0.2–0.375 % ropivacaine or 0.25 % bupivacaine (0.25 %
levobupivacaine) in post-herpetic neuralgia, vascular diseases and injuries, complex
regional pain syndrome (CRPS) types I and II, post-amputation pain. …
Stellate Ganglion Block
A Bhatia, PWH Peng – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… AACN Clin Issues. 2005;16:320–32.PubMedView Article; 25. Stanton-Hicks MD, Burton
AW, Bruehl SP, et al. An updated interdisciplinary clinical pathway for CRPS: report of
an expert panel. Pain Pract. 2002;2:1–16.PubMedView Article; 26. …
[HTML] The efficacy of different doses of Midazolam added to Lidocaine for upper extremity Bier block on the sensory and motor block characteristics and postoperative pain
A Honarmand, M Safavi, K Nemati, P Oghab – Journal of Research in Pharmacy …, 2015
… 24. 25. Coderre TJ, Xanthos DN, Francis L, Bennett GJ. Chronic post-ischemia pain (CPIP): A
novel animal model of complex regional pain syndrome-type I (CRPS-I; reflex sympathetic
dystrophy) produced by prolonged hindpaw ischemia and reperfusion in the rat. …
Complications of Peripheral Nerve Blocks
D Xu, A Hadzic – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… Coderre TJ, Xanthos DN, Francis L, Bennett GJ. Chronic post–ischemia pain (CPIP): a novel
animal model of complex regional pain syndrome–type I (CRPS–I; reflex sympathetic dystrophy)
produced by prolonged hindpaw ischemia and reperfusion in the rat. Pain. …
Functional neurological symptoms
A Carson, J Stone – Landmark Papers in Neurology, 2015
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www.ifssh.info volume 5 issue 3 aUgUSt 2015 WHAT Does THe PRACTiCe oF HAND
THeRAPy looK liKe iN iFsHT memBeR CouNTRies? CoNseRvATive …
Preparation of polydimethylaminoethyl methacrylate grafted attapulgite via ceric ion‐induced redox polymerization
H Xu, H Yang, S Xue, J Pan, Q Ni, F Gong – Journal of Applied Polymer Science, 2015
… interests.[10-12] Surface-initiated graft polymerizations of various monomers onto inorganic
nanoparticles have been reported by using UV-induced polymerization,[13] conventional radical
polymerizations,[14] and controlled/living radical polymerizations (CRPs).[15, 16] CRPs …
Total Elbow Arthroplasty for Distal Humerus Fractures
LS Harmer, J Sanchez-Sotelo – Hand Clinics, 2015
… Mansat et al, 31 2013, 87, 80:7, Age: >65 Isolated #, —, A: 9 B: 8 C: 70, CM: 85 Lat: 1 Discovery:
1, 37.5 (6–106) (100%), 86 (45–100), 29–125/—, Hematoma: 5 CRPS: 2 Skin necrosis: 1 Neuro
injury: 7 Deep infection: 1 Stem #: 1 Stem loosening: 2 Elbow stiffness: 2 Peripros #: 1 …
Sacral roots stimulation in chronic pelvic pain
P Sokal, P Zieliński, M Harat – Neurologia i Neurochirurgia Polska, 2015
… is not recommended because of long-term moderate effects and increased risk of major
complications [2]. The CPP with predominance of neuropathic pain can be the part of
failed-back-surgery syndrome (FBSS) or complex regional pain syndrome (CRPS) which are …
[PDF] Probabilistic temperature forecasting based on an ensemble AR modification
A Möller, J Groß – arXiv preprint arXiv:1508.01397, 2015
… Gneiting et al. (2005) propose to estimate the parameters by optimizing the continuous ranked
probability score (CRPS, Wilks, 2011) over the training data. … EMOS AR-EMOS SLP MAE 2.042
2.036 1.969 CRPS 1.471 1.460 1.407 DSS 3.135 2.908 2.821 …
The value of SPECT/CT in carpal boss
U Bhure, U Hug, MW Huellner, H Grünig, A Zander… – European Journal of …, 2015
… One patient was lost to follow-up after infiltration of CB. One patient had a complete response
to surgery initially but developed a CRPS (complex regional pain syndrome) some weeks after
surgery. … Infiltration with complete response; surgery performed; CRPS during follow-up. 5. …
Neurogenic neuroinflammation in fibromyalgia and complex regional pain syndrome
G Littlejohn – Nature Reviews Rheumatology, 2015
… fibromyalgia. Clinical features of CRPS. Neurogenic inflammation—comprising tissue
swelling, vasomotor changes and marked allodynia—also contributes substantially to
the clinical features of CRPS. … 91. Neuropeptides in CRPS. Increased …
[HTML] Memristive crypto primitive for building highly secure physical unclonable functions
Y Gao, DC Ranasinghe, SF Al-Sarawi, O Kavehei… – Scientific Reports, 2015
… Our novel architecture demonstrates desirable characteristics of PUFs, including uniqueness,
reliability, and large number of challenge-response pairs (CRPs) and desirable characteristics
of strong PUFs. … Number of CRPs. Figure 10: Number of CRPs. …
Methods for Treating GI Syndrome and Graft versus Host Disease
JA Rotolo, RN Kolesnick – US Patent 20,150,216,971, 2015
… Ceramide generated on the surface of endothelium coalesces to form ceramide-rich
platforms (CRPs) that transmit an apoptotic signal (Stancevic B., Kolesnick R.
Ceramide-rich platforms in transmembrane signaling. FEBS Lett. …
Multivariate postprocessing techniques for probabilistic hydrological forecasting
S Hemri, D Lisniak, B Klein – Water Resources Research, 2015
… river Lahn as these values lead to the best climatological forecasts in terms of the contin- uous
ranked probability score (CRPS, see equation (4)). The smaller the catchment, the … of the EMOS
model are estimated by minimization of the CRPS over the training pe- riod. …
Ambiguous anti‐fouling surfaces: Facile synthesis by light‐mediated radical polymerization
CW Pester, JE Poelma, B Narupai, SN Patel, GM Su… – Journal of Polymer Science …, 2015
… the prevention of marine biofouling.[7, 8]. Controlled radical, surface-initiated
polymerizations (SI-CRPs) provide a robust and versatile strategy for the formation
of grafted polymer brushes. A variety of techniques have been …
Fibromyalgia
Off-Label Trazodone Prescription: Evidence, Benefits and Risks
L Bossini, A Coluccia, I Casolaro, J Benbow… – Current Pharmaceutical …, 2015
… depression, insomnia, anxiety (then Gen- eralized Anxiety Disorder, Post-Traumatic Stress
Disorder, Obses- sive-Compulsive Disorder and Panic Disorder), off-label uses (then bulimia,
benzodiazepine abuse, alcohol withdrawal, fibromyalgia, dementia, schizophrenia and …
[PDF] Purification of A1PI from Human Plasma-an Improved Process to Achieve Therapeutic Grade Purity
NA Kumar, KL Rao, Z Chakraborthy, A Giri, KU Devi – J Chromatogr Sep Tech, 2015
… due to congenital A1PI deficiency but as evident from the available literature, due to the multiple
biological activities of A1PI, it has been associated with other lung diseases (cystic fibrosis) and
many non-pulmonary diseases like vasculitis, fibromyalgia, asthma, pancreatitis …
[PDF] Clinical features of musculoskeletal disorders due to hand-held devices
D Sharan – Proceedings 19th Triennial Congress of the IEA, 2015
… Associated Disorder n % Myofascial pain syndrome of neck and upper back 48 69
Thoracic outlet syndrome 34 49 Fibromyalgia syndrome 07 10 Hypothyroidism 02 2.9
Extensor wrist tendinosis 04 5.7 De Quervain’s tenosynovitis 02 2.9 …
[PDF] Outcome of treatment of work related musculoskeletal disorders in on-site clinics in information technology companies)
DSMMR Ranganathan – Proceedings 19th Triennial Congress of the IEA, 2015
… Common diagnosis made were Myofascial Pain Syndrome (49.20%), Fibromyalgia (8.5%),
Thoracic Outlet Syndrome (25.02%), Cubital Tunnel Syndrome (0.16%), Chronic Regional
Pain Syndrome (0.20%), and Wrist Tendinities (3.70%). …
COMPLEX PHYSIOTHERAPEUTIC PROGRAM FOR IMPACT ON INDIVIDUALS WITH CHRONIC PAIN IN THE BACK AND LOW BACK.
YV Pashkunova – Activities in Physical Education & Sport, 2015
… mechanical back pain associated with the work done are charac teristic for men.
Polymyalgia rheumatic, fibromyalgia, osteoporosis and diseases of parathyroid glands
are characteristic for women (Borenstein, 1998). Generally …
[HTML] Animal-Assisted Therapy for People with Chronic Pain
MOT Kristen Counts
… In 2013, a follow-up study was done with fibromyalgia patients (3) . Fibromyalgia is a disorder
characterized by widespread muscle pain that is accompanied by fatigue, sleep, memory, and
mood issues. … Of course, the exercise further decreased my fibromyalgia symptoms. …
[PDF] The barrier of hidden disabilities
Ε Βαβουράκη, Γ Παναγιάρης, Κ Σφλώμος – 2015
… hyperactivity disorder(AD/HD), asthma and allergies, bipolar disorder, psychiatric disorders,
depression, anxiety, cancer, cardiac or respiratory conditions, chronic fatigue syndrome, colour
blindness, cystic fibrosis, diabetes, epilepsy, seizure disorders, fibromyalgia, HIV/AIDS …
Superior Cervical Ganglion Block
D Jankovic – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… number of patients. These observations principally concern patients with
pain-associated depression in chronic pain conditions (various types of headache,
migraines, facial pain, post-nucleotomy pain, fibromyalgia, etc.). In the …
[HTML] Identification of α1-Antitrypsin as a Potential Candidate for Internal Control for Human Synovial Fluid in Western Blot
S Wang, J Zhou, X Wei, P Li, K Li, O Wang, F Wei… – Rheumatology: Current …, 2015
… Arthritis Res Ther 10: R117. Schmechel DE, Edwards CL (2012) Fibromyalgia, mood disorders,
and intense creative energy: A1AT polymorphisms are not always silent. Neurotoxicology
33: 1454-1472. Goldring MB, Goldring SR (2007) Osteoarthritis. …
[PDF] Examining the relationship between childhood victimization, health risk behaviors, and adult physical health outcomes among women on probation and parole.
TR Renn – 2015
… Chartier, Walker & Naimark (2009) Female & Male Obesity OR=1.61 Rohde et al. (2008)
Female Adjusted for age and race Obesity OR=1.84 Alexander et al (1998) Fibromyalgia
Heitkemper et al (2001) Irritable bowel syndrome Rich-Edwards, et al. …
Thalamic Mechanisms Underlying Alpha-Delta Sleep with Implications for Fibromyalgia
S Vijayan, EB Klerman, GK Adler, N Kopell – Journal of Neurophysiology, 2015
Abstract Alpha-delta sleep is the abnormal intrusion of alpha activity (8-13 Hz oscillations)
into the delta activity (1-4 Hz oscillations) that defines slow wave sleep. Alpha-delta sleep is
especially prevalent in fibromyalgia patients and there is evidence suggesting that the …
SP0131 Fibromyalgia: What is New
LJ Crofford – Annals of the Rheumatic Diseases, 2015
Abstract Further clarification of the impact of FM classification criteria has emerged with a
higher prevalence and greater proportion of men identified with the modified 2010 criteria.
This together with ongoing epidemiologic studies has confirmed the relationships …
Pelvic Floor and Urinary Distress in Women with Fibromyalgia
KD Jones, C Maxwell, SD Mist, V King, MA Denman… – Pain Management Nursing, 2015
Abstract Fibromyalgia (FM) patients were recently found to have more symptom burden from
bothersome pelvic pain syndromes that women seeking care for pelvic floor disease at a
urogynecology clinic. We sought to further characterize pelvic floor symptoms in a larger …
[PDF] Effects of transdermal magnesium chloride on quality of life for patients with fibromyalgia: a feasibility study
DJ Engen, SJ McAllister, MO Whipple, SS Cha, LJ Dion… – J Integr Med, 2015
ABSTRACT BACKGROUND: Fibromyalgia is a syndrome characterized by chronic pain,
fatigue, depression, and sleep disturbances. Its primary cause is unclear. Several studies
have reported decreased intracellular magnesium levels in patients with fibromyalgia and …
Neurogenic neuroinflammation in fibromyalgia and complex regional pain syndrome
G Littlejohn – Nature Reviews Rheumatology, 2015
Although fibromyalgia and complex regional pain syndrome (CRPS) have distinct clinical
phenotypes, they do share many other features. Pain, allodynia and dysaesthesia occur in
each condition and seem to exist on a similar spectrum. Fibromyalgia and CRPS can both …
Validation of fibromyalgia survey questionnaire and polysymptomatic distress scale in a Persian population
A Bidari, B Ghavidel-Parsa, AA Maafi, A Montazeri… – Rheumatology International, 2015
Abstract The aim of this study was to assess validity of the fibromyalgia survey questionnaire
(FSQ) and polysymptomatic distress scale (PSD) in an Iranian population. We also sought to
classify the severity levels of fibromyalgia (FM) symptoms according to the PSD scale. …
Health anxiety and depression in patients with fibromyalgia syndrome
M Uçar, Ü Sarp, Ö Karaaslan, AI Gül, N Tanik, HO Arik – Journal of International …, 2015
Methods Patients with FMS and healthy control subjects were recruited. All participants
completed the Health Anxiety Inventory Short Form (HAI-SF) and Beck Depression Inventory
(BDI). Pain was assessed in patients with FMS using the Fibromyalgia Impact …
Subgroups of fibromyalgia patients using the 1990 American College of Rheumatology criteria and the modified 2010 preliminary diagnostic criteria: the al-Ándalus …
V Segura-Jiménez, A Soriano-Maldonado… – Clinical and experimental …, 2015
OBJECTIVES: We aimed to investigate the symptom profiles in subsets of fibromyalgia
patients according to the subgroups created from the satisfaction of the 1990 American
College of Rheumatology (ACR) diagnostic criteria (1990c) and/or the modified 2010 ACR …
Effects of music on pain in patients with fibromyalgia
GB Alparslan, B Babadağ, A Özkaraman, P Yıldız… – Clinical Rheumatology, 2015
Abstract Fibromyalgia syndrome (FMS) is a chronic syndrome characterized by diffuse
musculoskeletal system pain and painful tender points in certain areas of the body. The aim
of the investigation was to determine the effects of music on pain in fibromyalgia patients. …
[HTML] Oral Burning With Dysphagia and Weight Loss
TM Seccia, G Rossitto, LA Calò, GP Rossi – Medicine, 2015
… Accepted June 22, 2015. Collapse Box Abstract. Abstract: Fibromyalgia is a disorder characterized
by an abnormal pain regulation. … We report on the case of a patient with fibromyalgia, who
presented with dysphagia, odynophagia, and glossodynia as prevalent symptoms. …
by admin | Jul 16, 2015 | Uncategorized
If you’re looking for natural ways to fight the aches, stiffness and inflammation of fibromyalgia, supplements can be a powerful weapon against symptoms. From vitamin D to brown seaweed extract, an arsenal of tools can help reduce pain. Here, experts reveal what works and why…
If you’re not including fibromyalgia-fighting supplements as part of your pain-management regimen, you could be missing out.
“The right supplements can help muscles relax, which leads to pain reduction, or even prevent pain altogether,” says fibromyalgia expert Jacob Teitelbaum, M.D., director of the Fatigue & Fibromyalgia Practitioners Network and author The Fatigue and Fibromyalgia Solution (Avery).
But when you’re standing in the supplement aisle, it’s hard to figure out which live up to their hype.
Read on for expert advice on the top 6 supplements for relieving fibro pain and other symptoms.
1. Vitamin D
The “sunshine vitamin” isn’t only good for building bones.
It can help fight fibro pain and fatigue, too, according to a 2014 study published in the journal Pain.
For the study, 30 women with fibromyalgia – who were also deficient in vitamin D – were divided into two groups. The treatment group received oral vitamin D supplements for 20 weeks. The control group received a placebo.
Starting after just one week, the treatment group showed improved physical functioning, had less morning fatigue than the placebo group and reported a marked reduction in pain.
The body produces vitamin D when skin is directly exposed to the sun – our best source. But some people don’t produce enough of the nutrient, according to the National Institutes of Health. These include women who are older, dark-skinned or obese.
People with certain disorders, including celiac or Crohn’s disease – as well as those who aren’t exposed to ample sunlight (or who wear sunscreen) – are also likely to be deficient. (Read about 11 natural remedies for Crohn’s management.)
Because few foods contain vitamin D, swallowing supplements is the easiest way to ensure you get enough.
The government’s daily recommendation of vitamin D is 600 international units (IU) for anyone 1 to 70 years old, and 800 IU for people 71 and up – to a maximum of 4,000 IU per day, according to the National Institutes of Health.
But ask your doctor how much you should take to combat your fibro symptoms.
2. Fish Oil
Thanks to its omega-3 fatty acids, fish oil has terrific anti-inflammatory properties, which can help reduce fibro pain.
It reduces the body’s production of inflammatory hormones (prostaglandins), says Nehad Soloman, M.D., a board-certified rheumatologist for Valley Arthritis Care in Arizona. And that may mean less stiffness or fewer tender joints.
Dr. Soloman suggests choosing a mercury-free brand (check the label), although fish oil supplements are considered safe.
Take 1 or 2 capsules (or 1 or 2 tablespoons) daily to reduce inflammation and boost your immunity, recommends the University of Maryland Medical Center. But check with your doctor first – especially if you take blood-thinning medications, such as aspirin or warfarin (Coumadin).
3. SAMe
S-Adenosyl methionine, more commonly known as SAMe, is a synthetic form of a compound the body naturally produces.
We need it for proper immune function, and it plays a role in forming cartilage and our DNA, Dr. Soloman says.
As we age, our bodies produce less of it, which may explain the increased aches after your 40th birthday. Taking a SAMe supplement not only lessens chronic pain, it also can boost your spirits. These 5 other natural mood-lifters help too.
“SAMe assists in the production and breakdown of neurotransmitters, such as serotonin, norepinephrine and dopamine – brain hormones that influence and regulate moods,” Dr. Soloman says.
In fibro studies, the recommended dosing is 400 mg twice a day for six weeks, starting with a lower dose (about 200 mg daily) and increasing gradually to avoid stomach upset, according to the University of Maryland Medical Center. But dosing varies by patient, so ask your doctor.
4. Ribose
Tight muscles are a common cause of fibro pain. To relax and release, muscles need energy, Dr. Teitelbaum says. And that’s where ribose supplements come in.
Ribose, a simple sugar, can increase energy by an average of 61% – and cut the pain experienced by fibromyalgia sufferers by an average of 15.6%, according to a 2012 study Dr. Teitelbaum led, published in The Open Pain Journal.
“The energy-building benefit of ribose directly improved the debilitating symptoms of this condition,” Dr. Teitelbaum says.
Dr. Teitelbaum recommends a 5 g dose three times a day.
5. Magnesium
This mineral is a major player in every body part.
Not only is it credited with keeping the heart, kidneys and bones strong, it also helps us avoid muscle spasms, weakness and back pain, Dr. Teitelbaum says.
Women with fibromyalgia may be deficient in magnesium, studies suggest. And magnesium may help relieve fibro pain and other symptoms.
For example, researchers from Ajou University School of Medicine in Korea analyzed hair samples from 166 women – including 44 with fibromyalgia. The hair from the fibromyalgia group contained significantly lower amounts of magnesium than that of the healthy women, according to the 2011 study.
Researchers at Acıbadem University Medical School in Istanbul, Turkey, also found that women diagnosed with fibromyalgia were likely to have “significantly lower” magnesium levels than women who didn’t have the disorder. But those who then took 300 mg/day of magnesium citrate for 8 weeks reported a reduction of “tender points” and other fibromyalgia symptoms, according to their 2013 study.
Magnesium is found in green leafy vegetables, pumpkin and sunflower seeds, 100% wheat bran cereal and raw spinach.
But these foods are a good source only if you eat them raw. Half of the minerals’ benefits are lost when cooked.
Normal daily recommended dosage for adult women is 280 to 300 mg per day, taken with meals, says the Mayo Clinic.
But if you have kidney disease or are taking medication, talk to your doctor before taking magnesium. Magnesium can interact with certain medications, including high blood pressure medicines and antibiotics, the University of Maryland Medical Center says.
6. Brown Seaweed Extract
You may not be familiar with these capsules, but this supplement is one to look for.
“It’s showing great promise in the fight against chronic pain,” Dr. Soloman says.
In fact, taking 1,000 mg of brown seaweed extract daily can reduce joint pain and stiffness by 52%, according to a 2011 study from Australia’s Centre of Health and Wellbeing, published in the journal Biologics.
Even better: These benefits kicked in after just one week, so you don’t have to wait long to find out if it’s working for you.
Supplement Smarts
Check with your doctor before taking these or other supplements.
“Like prescription drugs, it’s possible to take too much. And many supplements have side effects,” says David Pisetsky M.D., Ph.D., a professor of immunology at Duke University Medical Center in Durham, N.C.
Questions to ask your doctor include:
1. What’s the right dosage for me?
2. Should I take it with food?
3. What time of day should I take it?
4. Will this supplement interact badly with my prescriptions?
5. Does it have side effects that might mimic or aggravate my fibro symptoms (such as depression or sleep difficulties)?
For more expert advice and information, visit Lifescript’s Fibromyalgia Health Center.
Also, visit these other resources for more support:
The National Institutes of Health: Information and resources from the U.S. government’s medical research agency.
The American Fibromyalgia Syndrome Association: This group’s mission is to fund scientific studies on fibromyalgia.
Fibromyalgia Network: A nonprofit that offers information about the disease from top fibromyalgia clinicians and researchers.
by admin | Jul 7, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Withdrawal from Acute Amphetamine Induces an Amygdala-Driven Attenuation of Dopamine Neuron Activity: Reversal by Ketamine.
P Belujon, NL Jakobowski, HK Dollish, AA Grace – … : official publication of the …, 2015
Drug addiction is a chronic disorder characterized by a cycle composed of drug seeking,
intoxication with drug taking and withdrawal associated with negative affect. Numerous
studies have examined withdrawal/negative affect after chronic use; however, very few …
Enantioselective inhibition of D‐serine transport by (S)‐ketamine
NS Singh, M Bernier, S Camandola, MA Khadeer… – British Journal of …, 2015
Background and purpose Patients with major depressive disorder receiving racemic
ketamine,(R, S)-ketamine, experience transient increases in Clinician-Administered
Dissociative States Scale (CADDS) scores and coincident drop in plasma D-serine levels. …
Pain Management with Low-Dose Ketamine Infusions
A Katz – Emergency Medicine News, 2015
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. … The M 2 E Too! Blog by Larry Mellick, …
Sedative medications outside the operating room and the pharmacology of sedatives
TG Hansen – Current Opinion in Anesthesiology, 2015
… Ketamine. Ketamine is a unique phencyclidine derivate that differs from other sedatives in several
ways. … Ketamine seems to induce a dissociative anesthetic state with functional and
electrophysiological separation between the limbic system and hypothalamus. …
Pre-Emptive Analgesia with Ketamine for Relief of Postoperative Pain After Surgical Removal of Impacted Mandibular Third Molars
A Hadhimane, M Shankariah, KV Neswi – Journal of Maxillofacial and Oral Surgery, 2015
Purpose In this study we assessed the clinical efficacy of sub-mucosal injection of ketamine
at sub-anesthetic dose of 0.5 mg/kg on post-operative pain, swelling and trismus following
surgical extraction of impacted mandibular third molars. Methods Forty bilaterally …
Fluorescence‐guided surgery of human prostate cancer experimental bone metastasis in nude mice using anti‐CEA dylight 650 for tumor illumination
S Miwa, N De Magalhães, M Toneri, Y Zhang, W Cao… – Journal of Orthopaedic …, 2015
… Tumor implantation Six to eight-week-old male mice were anesthetized by a ketamine mixture
(10 µL ketamine HCL, 7.6 … Before resection of the metastatic tumor, mice were anesthetized with
the ketamine mixture (described above), and their limbs were sterilized with alcohol. …
Reassessment of the antioxidative mixture for the challenging electrochemical determination of dopamine, noradrenaline and serotonin in microdialysis samples
J Van Schoors, C Lens, K Maes, Y Michotte, I Smolders… – Journal of Chromatography …, 2015
… Diazepam 10 mg/2 mL is purchased as Valium ® from Roche (Cenexi, Fontenay-sous-Bois,
France), ketamine 1000 mg/10 mL as Ketamine 1000 ® from Ceva (Libourne, France), Ketoprofen
1% as Ketofen ® from Merial (Toulouse, France) and NaCl 0.9% from Baxter (Lessines …
Ultrasound-induced suppression of visually-evoked potentials: experience in nonhuman primates with a clinical transcranial MRI-guided focused ultrasound system
N McDannold, C Arvanitis, N Vykhodtseva… – Journal of Therapeutic …, 2015
… 650 kHz. Methods. The animal was deeply anesthetized using ketamine and
dexdormitor. First we targeted the LGN using MR temperature imaging, and then
we relocated the MRI table just outside the MRI. Visually-evoked …
Severe Acquired Idiopathic Thrombocytopenia in a Female Cynomolgus Macaque (Macaca fascicularis)
CM Parrula, J Mysore, H Burr, W Freebern, N Neef – Comparative Medicine, 2015
… On day 4, a follow-up complete physical exam under ketamine sedation (10 mg/kg IM; ketamine
hydrochloride, Fort Dodge Animal Health, Fort Dodge, IA), showed diffuse, pale-red discoloration
in both inguinal regions, as noted previously, and multifocal pinpoint foci of …
Estradiol protects female rats against sepsis induced by Enterococcus faecalis improving leukocyte bactericidal activity
RS Saia, FM Garcia, EC Cárnio – Steroids, 2015
… 0.5–1 × 10 10 CFU/animal) (time “zero” hour). At 6 and 24 h, rats were deeply
anesthetized (ketamine and xylazine at 55 and 10 mg/kg, respectively, ip) for sample
collection. As detailed in the subsequent sections, the blood …
Hot Off the Press: Subdissociative‐dose Ketamine for Acute Pain in the Emergency Department
AB Drake, WK Milne, CR Carpenter – Academic Emergency Medicine, 2015
… Social Media. Hot Off the Press: Subdissociative-dose Ketamine for Acute Pain in the Emergency
Department. … How to Cite. Drake, AB, Milne, WK, Carpenter, CR (2015), Hot Off the Press:
Subdissociative-dose Ketamine for Acute Pain in the Emergency Department. …
Optimization and application of an extraction procedure to determine drugs of abuse in solid environmental matrices of Turia River Basin
MJ Andres, R Alvarez, V Andreu, Y Pico – EGU General Assembly Conference …, 2015
… Amphetamine, methamphetamine, ethylamphetamine, ecstasy, ethylone, bk-MMBDB and MBDB
belong to phenylethylamine group; codeine and ketamine belong to opioid and phencyclidine
group, respectively, and benzoylecgonine is the major excreted metabolite of the …
Green spaces and cognitive growth in children
C Dieme – PNAS, 2015
… AG. Previous Section. Neural mechanism of ketamine. … Ketamine can produce rapid and
long-lasting antidepressant effects, but the drug’s potential for side effects and abuse limits its
widespread use, and the cellular mechanisms of ketamine’s effects are not yet known. …
Increasing use of ‘party drugs’ in people living with HIV on antiretrovirals: a concern for patient safety
M Bracchi, D Stuart, R Castles, S Khoo, D Back… – AIDS, 2015
… These substances are a combination of ‘club drugs’ (methylenedioxy- methamphetamine,
gamma-hydroxybutyrate, ketamine, benzodiazepine) and drugs that are more specifically used
in a sexualized context (methamphetamine, mephe- drone, poppers and erectile … Ketamine …
Halothane Modulates the Type I Interferon Response to Influenza and Minimizes the Risk of Secondary Bacterial Pneumonia through Maintenance of Neutrophil …
BA MacDonald, KV Chakravarthy, BA Davidson… – Anesthesiology, 2015
… The authors demonstrate that halothane mitigates the risk of SBP postflu through modulation
of the effects of type I interferon (IFN). METHODS: Mice (n = 6 to 15) were exposed to halothane
or ketamine and treated with influenza and Streptococcus pneumoniae. …
[HTML]Airtraq® laryngoscope-assisted fiberoptic bronchoscope intubation in a child with Pierre-Robin sequence: a case report
S Zhang, M Yi – International Journal of Clinical and Experimental …, 2015
… Sedation was achieved with IV dexmedetomidine 1 μg/kg and ketamine 1 mg/kg. … We
opted to use dexmedetomidine and ketamine in this child because they provide
sedation and analgesia without compromising respiratory drive. …
[HTML]Transcutaneous electric acupoint stimulation alleviates remifentanil-induced hyperalgesia in patients undergoing thyroidectomy: a randomized controlled trial
Y Chen, Y Yao, Y Wu, D Dai, Q Zhao, L Qiu – International Journal of Clinical and …, 2015
… Some medications, including ketamine, methadone, dextromethorphan, COX-2 inhibitors and
α 2 receptor agonists can modulate remifentanil-induced hyperalgesia [7]. Due to drug-related
side effects and longer duration of PACU stay, however, we have found these …
Impact of Obesity on Endotoxin-Induced Disseminated Intravascular Coagulation.
T Duburcq, A Tournoys, G Viviane, T Hubert, V Gmyr… – Shock, 2015
… animals). For the experiment, animals were premedicated with intramuscular injection of ketamine
(Ketamine 1000, 10 mg/kg of body weight; Virbac, Carros, France) and xylazine (Sedaxylan,
2.5 mg/kg of body weight; CEVA Santé Animale, Libourne, France). Then we …
Endocannabinoid signaling mechanisms in the substantia nigra pars reticulata modulate GABAergic nigrotectal pathways in mice threatened by urutu-cruzeiro …
RC Almada, CM Roncon, DH Elias-Filho, NC Coimbra – Neuroscience, 2015
… The surgeries were performed under deep anesthesia with 100 mg/kg ketamine (Ketamine
Agener, União Química Farmacêutica Nacional, São Paulo, Brazil) and 10 mg/kg xylazine
(Calmiun, União Química Farmacêutica Nacional, São Paulo, Brazil). …
ACUTE INHIBITION OF MONOAMINE OXIDASE AND ISCHEMIC PRECONDITIONING IN ISOLATED RAT HEARTS: INTERFERENCE WITH POSTISCHEMIC …
MD Dănilă, AI Privistirescu, SN Mirica, A Sturza… – Canadian Journal of …, 2015
… Male (body weight 400-450 g) and female (body weight 250-300 g) Wistar rats were anesthetized
with ketamine (Vetased, 30 mg/kg) and xylazine (Xylazin, 10 mg/kg) … Page 4 of 23 Page 5. 5
ketamine able to induce anesthesia was chosen in order to not interfere with the IPC- …
Radiofrequency Ablation (RFA)
In vitro artefact assessment of a new MR-compatible microwave antenna and a standard MR-compatible radiofrequency ablation electrode for tumour ablation
R Hoffmann, H Rempp, F Eibofner, DE Keßler… – European Radiology, 2015
Objective To evaluate and compare artefact configuration and diameters in a magnetic
resonance (MR)-compatible prototype microwave (MW) applicator and a standard MR-
compatible radiofrequency (RF) applicator for MR-guided tumour ablation. Methods Both …
Does Surgical Resection Provide Better Outcomes Than Radiofrequency Ablation in Patients With BCLC Very Early-stage Hepatocellular Carcinoma?.
C Li, TF Wen – Annals of Surgery, 2015
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. … Skip Navigation Links Home > …
Comparing outcome of radiofrequency ablation in Barrett’s with high grade dysplasia and intramucosal carcinoma: a prospective multicenter UK registry.
RJ Haidry, G Lipman, MR Banks, MA Butt, V Sehgal… – Endoscopy, 2015
Background and study aim: Mucosal neoplasia arising in Barrett’s esophagus can be
successfully treated with endoscopic mucosal resection (EMR) followed by radiofrequency
ablation (RFA). The aim of the study was to compare clinical outcomes of patients with …
Effectiveness of focal vs. balloon radiofrequency ablation devices in the treatment of Barrett’s esophagus
J Brown, B Alsop, N Gupta, DC Buckles, MS Olyaee… – United European …, 2015
Abstract Background and aims The safety and efficacy of radiofrequency ablation (RFA) in
treatment of Barrett’s esophagus (BE)-associated dysplasia has been well established. The
effectiveness of focal and balloon RFA devices has not been compared. Therefore, the …
Microwave Ablation: Comparison of Simultaneous and Sequential Activation of Multiple Antennas in Liver Model Systems
CM Harari, M Magagna, M Bedoya, FT Lee Jr… – Radiology, 2015
… Although both methods have been used in clinical studies of radiofrequency (RF) and microwave
ablation, an optimal delivery method has not yet been determined (6–9). Comparison studies
of sequential and simultaneous RF ablation techniques have concluded that …
Heparin Kinetics: The “Holy Grail” of Periprocedural Anticoagulation for ablation of atrial fibrillation
DF Briceno, A Natale, LD Biase – Pacing and Clinical Electrophysiology, 2015
… anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from
a multicenter prospective registry. … anticoagulation in patients undergoing radiofrequency ablation
for atrial fibrillation: results from a multicenter prospective registry. …
Catheter Ablation of Atrial Fibrillation Should Be Offered as Primary Therapy: What’s Your Hurry?
EF Wedam, MCP Haigney – Cardiac Electrophysiology Clinics, 2015
… medications. Radiofrequency ablation/cryoballoon ablation: a cure for atrial fibrillation?
Merriam-Webster’s … unknown. Does early radiofrequency ablation/cryoballoon ablation
prevent progression to permanent atrial fibrillation? A major …
OC-037 6 year disease durability outcomes on patients treated with endoscopic therapy for barrett’s related neoplasia from the uk registry
R Haidry, G Lipman, A Gupta, J Dunn, H Smart… – Gut, 2015
… Introduction Endoscopic therapy with combined Endoscopic mucosal resection (EMR) followed
by Radiofrequency ablation (RFA) is now the recommended first line … Thereafter patients underwent
RFA 3 monthly until all visible BE was ablated or cancer developed (endpoints). …
[HTML]Hybrid atrial fibrillation ablations and the increasing importance of the hybrid cardiovascular laboratory operating room
WJ Schleifer, JF Beshai, H Ramakrishna – Annals of Cardiac Anaesthesia, 2015
… the epicardium. [4] Moreover, endocardial catheters can check for the completeness
of the epicardial lesions and potentially identify gaps, which can then be addressed
with endocardial radiofrequency ablation. A similar approach …
[PDF]Effects of Hepatitis B Virus Load on Hepatectomy
M Wang, W Peng, TF Wen, LH He, C Li – Clin Microbiol, 2015
… MC: Milan Criteria; HR: Hepatic Resection; AFP: Alpha-Fetoprotein; OS: Overall Survival; RFS:
Recurrence-Free Survival; DNA: Deoxyribonucleic Acid; CT: Computed Tomography; MRI:
Magnetic Resonance Imaging; RFA: Radiofrequency Ablation; PEI: Percutaneous Ethanol …
HEALTH-RELATED QUALITY OF LIFE AFTER PERCUTANEOUS RADIOFREQUENCY ABLATION OF COLD SOLID BENIGN THYROID NODULES: A 2-YEAR …
R Valcavi, P Tsamatropoulos – Endocrine practice: official journal of the American …, 2015
OBJECTIVE: We studied the impact of Radiofrequency ablation (RFA) on health-related
quality of life (HRQL) in patients with benign thyroid nodules (TN) in a 2-year follow-up.
METHODS: Forty patients (35 female and 5 men; age 54.9±14.3 years) with cold thyroid …
Comparison of laparoscopic radiofrequency ablation versus open resection in the treatment of symptomatic-enlarging hepatic hemangiomas: a prospective study
X Zhang, L Yan, B Li, T Wen, W Wang, M Xu, Y Wei… – Surgical Endoscopy, 2015
Background Radiofrequency ablation (RFA) has been demonstrated to be a promising
therapy for symptomatic large hepatic hemangioma. However, there is a lack of studies to
demonstrate the benefits and disadvantages of RFA as compared with surgical resection …
… mucosal resection on the efficacy and safety of radiofrequency ablation for treatment of Barrett’s esophagus: results from the United States Radiofrequency Ablation …
N Li, S Pasricha, WJ Bulsiewicz, RE Pruitt… – Diseases of the Esophagus, 2015
Summary The effects of preceding endoscopic mucosal resection (EMR) on the efficacy and
safety of radiofrequency ablation (RFA) for treatment of nodular Barrett’s esophagus (BE) is
poorly understood. Prior studies have been limited to case series from individual tertiary …
… MicroRNA-122 Expression is a Poor Prognostic Marker in Patients with Hepatitis B Virus-related Hepatocellular Carcinoma who undergo Radiofrequency Ablation
HJ Cho, JK Kim, JS Nam, HJ Wang, J hee Lee, SS Kim… – Clinical Biochemistry, 2015
Objectives: Aim of this study was to investigate the prognostic potential of plasma microRNA-
122 levels in patients with hepatitis B virus (HBV)-related hepatocellular carcinoma after
hepatic resection or radiofrequency ablation (RFA).
[HTML]… efficacy enough to prevent stroke in atrial fibrillation patient with high CHADS2 score during peri-procedural catheter radiofrequency ablation? A case report with …
XM Shi, FK Chen, Z Liang, J Li, K Lin, JP Guo, ZL Shan – International Journal of …, 2015
Abstract Atrial fibrillation (AF) is a major cause of thromboembolic (TE) events including
stroke and transient ischemic attacks, catheter radiofrequency ablation (CA) has been
demonstrated to effectively eliminate AF in majority of patients. During the peri-procedural …
Right upper lobe lung cancer: Resection through left anterior mediastinotomy
M Sirois, WA Arab, E Turcotte, Y Poulin – Asian Cardiovascular and Thoracic Annals, 2015
… evaluation revealed a forced expiratory volume in 1 s of 1.8 L with carbon dioxide diffusion
capacity of 48% and maximal uptake of oxygen 14 mL min −1 kg −1 . Treatment including
stereotactic body radiation therapy, radiofrequency ablation, and surgery were discussed. …
Magnetic guidance versus manual control: comparison of radiofrequency lesion dimensions and evaluation of the effect of heart wall motion in a myocardial phantom
A Bhaskaran, MAT Barry, SI Al Raisi, W Chik… – Journal of Interventional …, 2015
… Abbreviations MNS Magnetic navigation system MC Manual control 1 Introduction Magnetic
navigation system (MNS) allows remote guidance of ablation catheters during radiofrequency
ablation for cardi- ac arrhythmias. … Page 3. 2.2 MNS versus MC radiofrequency ablation …
Thermal necrosis induced by electrocauterization as a local adjuvant therapy in local aggressive bone tumors, what is the safe limit for surgical margins? An …
M Aydin, K Basarir, M Armangil, HY Yildiz, Y Saglik… – Archives of Orthopaedic and …, 2015
… Majno PE, Mentha G, Mazzaferro V (2010) Partial hepatectomy versus radiofrequency ablation
for hepatocellular carcinoma: confirming the trial that will never be, and some comments on the
indications for liver resection. Hepatology 51(4):1116–1118PubMedView Article; 23. …
Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation
K Hayashi, T Konno, H Tada, S Tani, L Liu, N Fujino… – Circulation: Arrhythmia and …, 2015
Endoscopic Management of Early Esophageal Cancer.
JA Barnes, FF Willingham – Journal of Clinical Gastroenterology, 2015
… proportionately. In the past decade, radiofrequency ablation has become the standard
first-line therapy for high-grade dysplasia when found in the precursor lesion to
esophageal adenocarcinoma, Barrett’s esophagus. Success …
Chronic Regional Pain Syndrome (CRPS/RSD)
V33. Functional imaging of somatosensory finger representation and intracortical inhibition modulation in complex regional pain syndrome
S Strauss, M Grothe, T Usichenko, W Byblow, M Lotze – Clinical Neurophysiology, 2015
Neurophysiological pathology in CRPS type I is characterized by somatosensory and motor deficits.
Transcranial magnetic stimulation (TMS) and functional MRI rev. … Neurophysiological pathology
in CRPS type I is characterized by somatosensory and motor deficits. …
Exploiting resistive cross-point array for compact design of physical unclonable function
PY Chen, R Fang, R Liu, C Chakrabarti, Y Cao, S Yu – Hardware Oriented Security …, 2015
… primitive that leverages the inherent randomness in the physical systems (eg the semiconductor
manufacturing process) to produce a unique response (output) for a given challenge (input)
[1]. Depending on the number of possible challenge-response pairs (CRPs), PuFs can …
Do psychological factors influence recovery from Complex Regional Pain Syndrome Type-1? A Prospective Study.
DJ Bean, MH Johnson, W Heiss-Dunlop, AC Leed… – PAIN, 2015
… Conflicts of Interest: none declared. Running Head: “Psychological factors in the recovery from
CRPS-1” Number of Pages: 19 Number of Tables: 3 Number of Figures: 1 Summary: Amongst
patients with recently-onset CRPS-1, those with higher levels of pain-related …
A comparison of linear and non-linear data assimilation methods using the NEMO ocean model
P Kirchgessner, J Tödter, L Nerger – EGU General Assembly Conference Abstracts, 2015
…pdaf.awi.de), which ensures identical experimental conditions for both filters. To
account for the nonlinearity, the assimilation skill of the two methods is assessed
by using different statistical metrics, like CRPS and Histograms.
The total probabilities from high-resolution ensemble forecasting of floods
J Olav Skøien, K Bogner, P Salamon, P Smith… – EGU General Assembly …, 2015
… Weather Rev., 135(4), 1386-1402, doi:10.1175/MWR3341.1, 2007. Gneiting, T., Raftery,
AE, Westveld, AH and Goldman, T.: Calibrated Probabilistic Forecasting Using Ensemble
Model Output Statistics and Minimum CRPS Estimation, Mon. …
Efficacy of combined physical and occupational therapy in patients with conservatively treated distal radius fracture: randomized controlled trial
V Filipova, D Lonzarić, BJ Papež – Wiener klinische Wochenschrift, 2015
… Two participants from group A and two from group B were suspected of having complex
regional pain syndrome (CRPS) type I yet were not excluded from the trial since there
was no significant deviation regarding the observed variables. …
Combining Graph Analysis and Recurrence Plot on fMRI data
A Lombardi, P Guccione, L Mascolo, P Taurisano… – Medical Measurements and …, 2015
… Even if a visual inspection of CRPs can reveal valuable information about the relationship between
the two systems, the quantification of the structures in CRPs through CRQA has been used for
making more objective the comparison between the time series. Page 3. …
Improving Precipitation Forecasts by Generating Ensembles through Postprocessing
DL Shrestha, DE Robertson, JC Bennett, QJ Wang – Monthly Weather Review, 2015
… In this study, the forecast 3 performance is characterized by evaluating the bias, the Continuous
Ranked Probability Score 4 (CRPS), reliability and Relative Operating Characteristics (ROC)
to assess different aspects of 5 forecast quality. 6 … The mean CRPS (hereafter 16 …
The Forecast Skill Horizon
R Buizza, M Leutbecher – Quarterly Journal of the Royal Meteorological Society, 2015
… theoretical tools are deemed to be impractical to use. We select the continuous ranked probability
score (CRPS, Brown 1974, Hersbach 2000) as metric to decide when the … closer to the observed
CDF (bottom panel). The CRPS is equal to the mean squared error …
Functional Outcomes Following Bridge Plate Fixation for Distal Radius Fractures
A Lauder, S Agnew, K Bakri, CH Allan, DP Hanel… – The Journal of Hand …, 2015
… 2/134 deep infection. 2/134 extensor tendon adhesions. 1/134 EPL rupture. DASH: N/A. Hanel
et al 13, IV: retrospective chart review, 62 pts via chart review, second metacarpal, No CRPS,
1/62 ECRL rupture, 1/62 hardware failure, 0/62 postoperative digit stiffness. DASH: N/A. …
New findings implicated in Coronary calcification in Chronic phase Kawasaki disease
T Yahata, K Ikeda, A Hamaoka, C Suzuki, A Yoshioka… – Circulation, 2015
… tomography. We measured %FMD as an endothelial function marker and hs-CRPs
as an inflammatory marker, serum hydroperoxide and urinary 8-OHdG as oxidative
stress markers, and the bone mineral density (BMD). Patients …
[PDF]Evaluation of the Red Sea State Food Security Status 2007-2009
AAA Ahmed – 2015
… nutrition monitoring using MUAC Since 2006 no nutrition survey conducted. However, EWS
started collecting the nutrition information using the Community Resource Persons (CRPs)
to follow up the nutrition situation in sentinel sites in RPS and Tokar. …
Spatio-temporal circular models with non-separable covariance structure
G Mastrantonio, GJ Lasinio, AE Gelfand – TEST, 2015
Page 1. TEST DOI 10.1007/s11749-015-0458-y ORIGINAL PAPER Spatio-temporal
circular models with non-separable covariance structure Gianluca Mastrantonio1 ·
Giovanna Jona Lasinio2 · Alan E. Gelfand3 Received: 7 …
Predictors of Spinal Cord Stimulation Success
P De La Cruz, C Fama, S Roth, J Haller, M Wilock… – … : Technology at the Neural …, 2015
… Failure, Success. CRPS, Complex Regional Pain Syndrome; FBSS, Failed Back Surgery
Syndrome. Age, Mean + Range, 47.8 + 25.0, 51.2 + 53. Gender, Male : Female, 3:7, 20:27. … Hybrid
(%), 0, 8.1. Indication, FBSS (%), 60, 37.8. CRPS (%), 20, 37.8. Neuritis (%), 20, 24.3. …
Physical Therapy Examination and Assessment
JM David, C OCS, M Ariana Brutico – journal of orthopaedic & sports physical therapy, 2015
… Why Are My Nerves So Sensitive? Neuroscience Education for Patients With CRPS
or RSD. Authors: Ariana Brutico, MSPT, PhD. AFFILIATION: Body Dynamic: Outpatient
Physical Therapy, Pilates, and Yoga Clarks Summit, PA. …
Improved model output statistics of numerical weather prediction based irradiance forecasts for solar power applications
RA Verzijlbergh, PW Heijnen, SR de Roode, A Los… – Solar Energy, 2015
… irradiance is zero. The evaluation of the probabilistic forecasts is carried out using
two metrics. The first is the continuous ranked probability score (CRPS): equation(9).
CRPS ( k ) = 1 T ∑ t = 1 T ∫ x F ̂ t + k | t ( x ) – H ( x – y t + k ) 2.
Thoracic sympathectomy: a review of current indications
M Hashmonai, AEP Cameron, PB Licht, C Hensman… – Surgical Endoscopy, 2015
… However, because the role of the autonomous nervous system is obscure in the pathogenesis
of these disorders, the term “Complex regional pain syndrome” (CRPS) is preferred. … There is
very little good evidence in the literature to guide treatment of CRPS. …
NGF-induced synapse-like structures in contralateral sensory ganglia contribute to chronic mirror-image pain.
CF Cheng, JK Cheng, CY Chen, RH Rau, YC Chang… – Pain, 2015
… image (contralateral) side [21]. This symptom has been observed in many clinical
pain conditions, such as complex regional pain syndrome (CRPS) [23], rheumatoid
arthritis [35], fibromyalgia [4], and neuropathic pain [27]. Mirror …
Process Documentation Research and Impact of Community-Driven Development Grants Research in Rural India, Socioeconomics Discussion Paper Series 34
M Bhattarai, Y Mohan Rao, BL Varalakshmi, VD Duche… – 2015
… Item Type: Socioeconomics Discussion Paper Series. Divisions: RP-Market Institutions
and Policies. CRPS: CGIAR Research Program on Policies, Institutions, and Markets.
Series Name: Socioeconomics Discussion Paper Series. …
SCAMP: A new tool for an old problem
RH Rathod – Journal of Hospital Medicine, 2015
… BWH, Brigham and Women’s Hospital; CRPS, complex regional pain syndrome; EPL, extensor
pollicis longus; PFL, Flexor pollicis longus; MRN, medical record number; N/A, not applicable;
OT, occupational therpay; PA, physician’s assistant. Download figure to PowerPoint. …
Fibromyalgia
Results of an active neurodynamic mobilization program in patients with fibromyalgia syndrome: a randomized controlled clinical trial
JR Torres, IC Martos, IT Sánchez, AO Rubio… – Archives of Physical …, 2015
To examine the effects of an active neurodynamic mobilization program on pain, neurodynamics,
perceived health state and fatigue in patients with fibromyalgia s. … Setting. A local Fibromyalgia
Association. Participants. 48 patients with fibromyalgia syndrome. Interventions. …
The evaluation in terms of sarcopenia of patients with fibromyalgia syndrome
I Koca, E Savas, ZA Ozturk, A Boyaci, A Tutoglu… – Wiener klinische …, 2015
Background Fibromyalgia syndrome (FMS) is an extra-articular rheumatic illness,
characterized by widespread body pain and decreased muscle function. Generalized loss of
muscle mass and strength is named as sarcopenia. The objective of this study was to …
Stigma, Unspeakable Dilemmas, and Somatic Symptoms–a Legacy of Suffering in CFS/ME and Fibromyalgia
J Griffith, N Ryan – Meanings of ME: Interpersonal and Social Dimensions …, 2015
Chronic fatigue syndrome (CFS) and fibromyalgia are both illnesses for which suffering is
amplified by stigmatisation. People with these illnesses often feel judged, devalued,
marginalised, or discriminated against by employers, family members, friends and, most of …
[PDF]Quantitative analysis of nailfold capillary morphology in patients with fibromyalgia
DH Choi, HS Kim – Korean Journal of Internal Medicine, 2015
Background/Aims: Nailfold capillaroscopy (NFC) has been used to examine morphological
and functional microcirculation changes in connective tissue diseases. It has been
demonstrated that NFC patterns reflect abnormal microvascular dynamics, which may play …
Fibromyalgia incidence among patients with hepatitis B infection
L Yazmalar, Ö Deveci, İ Batmaz, D İpek, T Çelepkolu… – International Journal of …, 2015
Aim The purpose of our investigation was to evaluate the incidence of fibromyalgia
syndrome (FMS) and identify FMS-related clinical symptoms in hepatitis B virus (HBV)
patients. Methods One hundred and eighteen HBV surface antigen (HbsAg)-positive …
[PDF]Rheumatology: Current Research
EÖ Bulduk, B Biral – 2015
Page 1. Treatment Approaches of Juvenile Fibromyalgia Syndrome … Abstract Juvenile
fibromyalgia syndrome (JFMS) is an idiopathic long-term health condition characterized
by widespread musculoskeletal pain in children and adolescents. …
Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue
CD Ward – 2015
… 10 11 12 13 14 The Challenge of CFS/ME in Primary Care Laura Saunders The Said and the
Unsaid: Ambivalence in CFS/ME Christopher D. Ward Stigma, Unspeakable Dilemmas, and
Somatic Symptoms–a Legacy of Suffering in CFS/ME and Fibromyalgia James Griffith and …
AMPK phosphorylation modulates pain by activation of NLRP3-inflammasome
P Bullon, E Alcocer-Gómez, AM Carrión… – Antioxidants and Redox …, 2015
… Deficient AMPK activation and over-activation of NLRP3-inflammasome axis was also observed
in blood cells from patients with Fibromyalgia (FM), a prevalent human … some pain conditions as
neuropathic pain, fibromyalgia (FM), and complex regional pain syndrome (6,15,16). …
Is Chronic Pain a Disease in Its Own Right? Discussions from a Pre-OMERACT 2014 Workshop on Chronic Pain
AM Taylor, K Phillips, JO Taylor, JA Singh… – The Journal of …, 2015
… In a review of functional disorders36, various mechanisms were proposed to explain the cause
of conditions such as irritable bowel syndrome, fibromyalgia, temporomandibular joint disorder,
and inter- stitial cystitis, including enhanced pain perception, altered brain activation …
Compendium for the Antenatal Care of High-Risk Pregnancies
H Narayan – 2015
AB1222-HPR Hypervigilance to Emotional Subliminal Images in Patients with Fibromyalgia
I Peláez, F Mercado, P Barjola, S Cardoso – Annals of the Rheumatic Diseases, 2015
Background Fibromyalgia (FM) is a chronic condition characterized by the presence of pain,
fatigue and cognitive dysfunction, among other symptoms. Previous research (Duschek et
al., 2014) also indicated that patients show an hypervigilance pattern to pain and negative …
[HTML]Temporal analysis of pain responders and common adverse events: when do these first appear following treatment with pregabalin
J Fink, B Emir, B Parsons, A Clair – Journal of Pain Research, 2015
… Clair Pfizer, New York, NY, USA Background: Pregabalin is an α2δ ligand indicated in the USA
for treatment of a number of chronic pain conditions, including diabetic peripheral neuropathy,
postherpetic neuralgia, pain associated with spinal cord injury, and fibromyalgia. …
SP0133 Juvenile Idiopathic Arthritis and Other Pediatric Rheumatic Diseases
T Avcin – Annals of the Rheumatic Diseases, 2015
… The clinical trials of CCX168, a small molecule antagonist of human C5aR, in human is underway.
Disclosure of Interest: None declared DOI: 10.1136/annrheumdis-2015-eular.6705 FRIDAY, 12
JUNE 2015 WIN session 5 SP0131 FIBROMYALGIA: WHAT IS NEW LJ Crofford. …
Neuropathic pain as part of chronic widespread pain: environmental and genetic influences.
SK Momi, SM Fabiane, G Lachance, G Livshits… – Pain, 2015
…frances.williams@kcl.ac.uk; +44 (0) 20 7188 6765 Keywords: chronic widespread pain;
neuropathic pain; genetic; fibromyalgia; twin ACCEPTED … ABSTRACT Chronic widespread pain
(CWP) has complex aetiology and forms part of the fibromyalgia syndrome. …
SP0130 C5A and its Receptor in Anca-Associated Vasculitis
MH Zhao – Annals of the Rheumatic Diseases, 2015
… The clinical trials of CCX168, a small molecule antagonist of human C5aR, in human is underway.
Disclosure of Interest: None declared DOI: 10.1136/annrheumdis-2015-eular.6705 FRIDAY, 12
JUNE 2015 WIN session 5 SP0131 FIBROMYALGIA: WHAT IS NEW LJ Crofford. …
The spectrum of noncoeliac gluten sensitivity
I Aziz, M Hadjivassiliou, DS Sanders – Nature Reviews Gastroenterology & …, 2015
… with NCGS is described as well as the symptom manifestations commonly reported after gluten
exposure, which include intestinal symptoms consistent with IBS, and extraintestinal symptoms
such as neurological dysfunction, psychological disturbances, fibromyalgia and skin …
Neuro-Bio-Behavioral Mechanisms of Placebo and Nocebo Responses: Implications for Clinical Trials and Clinical Practice
M Schedlowski, P Enck, W Rief, U Bingel – Pharmacological Reviews, 2015
Health-related quality of life improvements among women with chronic pain: comparison of two multidisciplinary interventions
SV Björnsdóttir, M Arnljótsdóttir, G Tómasson, J Triebel… – Disability & Rehabilitation, 2015
… 18,19]. Recently published systematic reviews on multidisciplinary programs for
people with chronic pain [19], chronic low back pain [20] or fibromyalgia syndrome
[21] agree on recommended content in such programs. This …
NGF-induced synapse-like structures in contralateral sensory ganglia contribute to chronic mirror-image pain.
CF Cheng, JK Cheng, CY Chen, RH Rau, YC Chang… – Pain, 2015
… image (contralateral) side [21]. This symptom has been observed in many clinical
pain conditions, such as complex regional pain syndrome (CRPS) [23], rheumatoid
arthritis [35], fibromyalgia [4], and neuropathic pain [27]. Mirror …
Physical Therapy Examination and Assessment
JM David, C OCS, M Ariana Brutico – journal of orthopaedic & sports physical therapy, 2015
… and nerve sensitivity. It is one of several manuals written by the primary author, all
of which discuss concurrent topics involving pain and recovery from injury, including
whiplash, headaches, and fibromyalgia. The manual begins …
by admin | Jun 30, 2015 | Uncategorized
A clinical study conducted by researchers at the Leiden University Medical Center in The Netherlands evaluated the efficacy of a multi-day infusion regimen of intravenous ketamine for the treatment of Chronic Regional Pain Syndrome Type 1. This double blind, placebo-controlled study validated intravenous ketamine as a treatment for CRPS-1, which historically responds poorly to standard pain treatment. Sixty CRPS-1 patients were randomized into groups to undergo infusion therapy for 4.2 days with intravenous ketamine or placebo. The researchers measured pain levels in these patients using a numerical pain score assessment. They found that pain scores over the 12 week study period in patients receiving ketamine were significantly lower compared to those that received placebo (P<0.001). Importantly, after the 12th week, statistical significance between the two groups was lost, indicating that the infusion regimen that the researchers used is not a permanent fix for CRPS-1. Nonetheless, it did provide relatively long lasting relief in a patient population that is desperate for more effective therapies. Intravenous ketamine could be the answer that they’re looking for.
Future studies should focus on the optimal dose of intravenous ketamine and possible synergistic combination drugs to enhance the efficacy of this treatment option for the treatment of chronic pain conditions, like CRPS. A new combination ketamine infusion therapy is offered at the Florida Spine Institute that might just be the answer for long lasting analgesic efficacy. To find out if this procedure is right for your chronic pain, please make an appointment to see Dr. Ashraf Hanna, an expert pain management doctor with significant experience using intravenous ketamine. It is our goal at the Florida Spine Institute to conduct the cutting edge research necessary to eradicate CRPS once and for all.
Full Citation:
Sigtermans, M.J., van Hilten, J.J., Bauer, M.C., Arbous, M.S., Marinus, J., Sarton, E.Y., Dahan, A., 2009. Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1. Pain 145, 304-311.
