by admin | Oct 1, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Ketamine Derivatives
JW Sleigh, WA Denny, J Jose, SA Gamage, MG Harvey… – US Patent 20,150,259,277, 2015
Abstract: The present invention relates to ketamine derivatives of the formula (I),
pharmaceutical compositions comprising them, and methods for treating pain comprising
administering them, and their use in the manufacture of medicaments for treating pain. …
Comparing the hemodynamic parameters and seizure duration between ketamine and thiopental during Electroconvulsive therapy in patients with Major depressive …
M Mohseni, A Ghanbari, MA Motazedi Ghajar… – Anesthesiology and Pain, 2015
Aim and Background: Today the effect of Electroconvulsive therapy (ECT) in cure of Major
depressive disease (MDD), and psychiatric patients is well accepted and usage of this
method is developed every day. In this regard, selecting the most effective hypnotic drugs …
The antinociceptive efficacy of morphine-ketamine-magnesium combination is influenced by the order of medication administration.
SM Vučkovič, VKR Savič, DP Srebro, BM Medič… – European review for …, 2015
OBJECTIVE: Ketamine and magnesium, both N-methyl-D-aspartate (NMDA) receptor
antagonists, enhance the antinociceptive effects of opioid analgesics in different animal
models of pain, as well as in humans. This study aimed at evaluating whether magnesium …
[HTML] Hemodynamic Effects of the Non-Peptidic Angiotensin-(1-7) Agonist AVE0991 in Liver Cirrhosis
S Klein, CB Herath, R Schierwagen, J Grace… – PLOS ONE, 2015
… Cholestatic model. BDL was performed in 40 rats (180g) after anesthesia with ketamine/xylazine
(78mg/kg and 10mg/kg body weight) as previously described [12]. … Briefly rats were anesthetized
with ketamine/xylazine (78mg/kg and 10mg/kg body weight), respectively. …
[HTML] Systemic and Cardiac Depletion of M2 Macrophage through CSF-1R Signaling Inhibition Alters Cardiac Function Post Myocardial Infarction
AL Leblond, K Klinkert, K Martin, EC Turner, AH Kumar… – PLOS ONE, 2015
… Procedures were performed under anesthesia induced by ketamine (90mg/kg), xylazine
(10mg/kg) and urethane (1.25mg/kg) and analgesia by ip delivery of carprofen (5 mg/Kg). … Mice
were anesthetized with ketamine (90mg/kg), xylazine (10mg/kg) and urethane (1.25mg/kg). …
Morphological Pulmonary Diffusion Capacity for Oxygen of Burmese Pythons (Python molurus): a Comparison of Animals in Healthy Condition and with Different …
JM Starck, I Weimer, H Aupperle, K Müller… – Journal of Comparative …, 2015
… Snakes were anaesthetized (1 mg/kg diazepam intramuscularly [i/m]; Faustan; Temmler Pharma,
Marburg, Germany, followed by 40 mg/kg ketamine hydrochloride i/m; Ketavet; Pfizer Pharma,
Berlin, Germany) and placed in the CT scanner (Brilliance CT 6; Philips, Hamburg …
[PDF] Articles in PresS. Am J Physiol Lung Cell Mol Physiol (March 27, 2015). doi: 10.1152/ajplung. 00291.2014
BA MacKenzie, I Henneke, S Hezel, D Al Alam… – 2015
… Mice were genotyped as described previously (3, 12, 34). 148 149 Bleomycin administration
150 10–14 week-old female mice were anaesthetized with a mixture of 0.6 µl/g Ketamine 10%
151 (100 mg/ml) and 0.3 µl/g Dormitor 10% (0.5 mg/ml) dissolved in 0.7% saline. …
Anesthesia for Endoscopy
M Asakawa – Veterinary Clinics of North America: Small Animal …, 2015
… 26 Another study found that a combination of acepromazine and butorphanol followed by induction
with propofol had minimal effect on splenic volume, whereas medetomidine and butorphanol
as premedicants followed by ketamine and diazepam for induction were associated …
[HTML] Generation and Characterization of Live Attenuated Influenza A (H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation
S Shcherbik, N Pearce, A Balish, J Jones, S Thor… – PLOS ONE, 2015
… replication in multiple organs. Anesthesia occurred through an intramuscular injection
of a ketamine-xylazine-atropine cocktail (25 mg/kg ketamine, 2 mg/kg xylazine,
and 0.05 mg/kg of atropine). For euthanasia, ferrets were …
[HTML] Standardized surgical approaches to ear surgery in rats
P Li, D Ding, K Gao, R Salvi – Journal of Otology, 2015
… studies using rats. 2. Anesthesia and pre-operative preparation. Health SD rats
weighing about 250 g were selected and anesthetized with intraperitoneal ketamine
(100 mg/kg) and chlorpromazine (5 mg/kg). The skin around …
Radiofrequency Ablation (RFA)
Is radiofrequency ablation of lung metastases the most radical treatment?
M Zielinski, R Zaimi, P Sabatier, P Bagan – European Journal of Surgical Oncology, 2015
We read with interest the article on long term results of radiofrequency ablation (RFA) to lung
metastases from colorectal cancer 1. This article is an interesting retrospective analysis on
long term survival in patients with lung metastases from colorectal cancer treated with this …
Uninterrupted new oral anticoagulants compared to uninterrupted Vitamin K antagonists in ablation of atrial fibrillation. A Meta-analysis
R Nairooz, K Ayoub, P Sardar, J Payne, A Almomani… – Canadian Journal of …, 2015
… NOAC= new oral anticoagulant, VKA=vitamin K antagonist, N/A=not available, TEE=
trans-esophageal echocardiogram, ICE= intra-cardiac echocardiogram, UFH=
unfractionated heparin, s= seconds, RFA= radiofrequency ablation. …
Magnetic resonance imaging of atrial fibrosis: redefining atrial fibrillation to a syndrome
P Gal, NF Marrouche – European Heart Journal, 2015
… Post-ablation DE-MRI allows for assessment of the total scar burden, complete encirclement
of pulmonary veins, and the assessment of residual fibrosis, which were all reported to
be strong predictors of arrhythmia recurrences post-ablation. …
Imaging Hepatocellular Carcinoma with Dynamic CT Before and After Transarterial Chemoembolization: Optimal Scan Timing of Arterial Phase
M Saake, MM Lell, A Eller, W Wuest, M Heinz, M Uder… – Academic Radiology, 2015
… In eight patients previous TACE and in five patients previous radiofrequency ablation had been
performed and follow-up imaging had demonstrated HCC recurrence. … First, in a part of our cohort
the HCCs had been treated previously by TACE or radiofrequency ablation. …
Efficacy of Antiarrhythmic Drugs Short-Term Use After Catheter Ablation for Atrial Fibrillation (EAST-AF) trial
K Kaitani, K Inoue, A Kobori, Y Nakazawa, T Ozawa… – European Heart Journal, 2015
… fasttrack ★ Efficacy of Antiarrhythmic Drugs Short-Term Use After Catheter Ablation
for Atrial Fibrillation (EAST-AF) trial. Kazuaki Kaitani, Koichi Inoue, Atsushi Kobori,
Yuko Nakazawa, Tomoya Ozawa, Toshiya Kurotobi, Itsuro …
PAEDIATRIC CT EXPOSURE PRACTICE IN THE COUNTY OF RIO DE JANEIRO: THE NEED TO ESTABLISH DIAGNOSTIC REFERENCE LEVELS
FM de Jesus, LAG Magalhães, S Kodlulovich – Radiation Protection Dosimetry, 2015
… are essential for the diagnosis and monitoring of patients with complex cardiovascular disease
(2–4) , for the diagnosis of pulmonary embolism (5) and for guiding interventional procedures,
such as radiofrequency ablation, biopsy, abscess drainage and nephrostomy (6) . In …
Substrate Mapping for Unstable Ventricular Tachycardia
P Santangeli, FE Marchlinski – Heart Rhythm, 2015
… Scar dechanneling, linear ablation through sites matching VT with pacing and the core isolation
approach focus on more discrete … and/or inducible arrhythmias by means of physiological
maneuvers, although this does not necessarily translate in less radiofrequency lesions to …
[HTML] Evaluation and management of chronic coccygodynia: Fluoroscopic guided injection, local injection, conservative therapy and surgery in non-oncological pain
A Galhom, M al-Shatouri, SA El-Fadl – The Egyptian Journal of Radiology and …, 2015
… 23). The beneficial effect was retained with repeated injections (21). Radiofrequency
ablation using two needles achieved a pain reduction of >50% for an average duration
of 2.2 months, in a series of 13 patients (24). Another …
[HTML] Assessment of prognosis of patients with stage II colon cancer
S Martins, P Martins – Journal of Coloproctology, 2015
… Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined
resection/ablation for colorectal liver metastases. Ann. Surg., 239 (2004), pp. 818–825 discussion
825–27. 9; K. Lang, JR Korn, DW Lee, LM Lines, CC Earle, J. Menzin; …
Energy delivery systems and uses thereof
DW van der Weide, PF Laeseke, FT Lee, CL Brace – US Patent 9,119,649, 2015
… tissue for a wide variety of applications, including medical procedures (eg, tissue ablation,
resection, cautery … the device is configured to deliver a sufficient amount of energy to ablate the
tissue … In some embodiments, the energy is microwave energy and/or radiofrequency energy …
Chronic Regional Pain Syndrome (CRPS/RSD)
Side-Channel Assisted Modeling Attacks on Feed-Forward Arbiter PUFs Using Silicon Data
R Kumar, W Burleson – … : 11th International Workshop, RFIDsec 2015, New …, 2015
… However, the performance of modeling attacks is impacted by the presence of
error-prone CRPs in the training set. To that extent … error-prone CRPs. The terms
“error-prone” and “error- inflicted” refer to the same set of CRPs. …
Making Invisible Intersectionality Visible Through Theater of the Oppressed in Teacher Education
B Powers, PB Duffy – Journal of Teacher Education, 2015
… Thank you! We ended there on the first day. Day 2. After initial warm-ups, the students broke up
into four groups. Each group, of about five to six students, was asked to create two to three
tableaux that explored their positions within schools as it relates to the course of CRPs. …
Energy geographies: thinking critically about energy issues in the classroom
E Delgado – Journal of Geography in Higher Education, 2015
Analysis of suicide attempts and completions at the South Texas Veterans Health Care System: a retrospective review
R Oliveira, TA Moore, CA Gutierrez – Mental Health Clinician, 2015
… Additional information collected included psychiatric medications used during the review period,
including psychiatric MPRs for 6 months before the suicide attempt. The MPRs were calculated
manually using the prescription refill history available in CRPS. …
[PDF] Cadmium toxicity in diazotrophic Anabaena spp. adjudged by hasty up-accumulation of transporter and signaling and severe down-accumulation of nitrogen …
S Rai, S Singh, LC Rai – 2015
… Percentage of total protein variability explained in PC1 and PC2 is given in parenthesis.
Protein spots in red color represent variables whereas text in blue color indicates time points.
Fig. 5. Cluster analysis of Cd responsive (CRPs) in Anabaena spp. …
[PDF] The migraine brain in transition: girls vs boys
V Fariaa, N Erpeldinga, A Lebela, A Johnsona… – 2015
Page 1. NUMBER 1 OF 1 AUTHOR QUERIES DATE 7/25/2015 JOB NAME PAIN ARTICLE
PAIN-D-14-13318 QUERIES FOR AUTHORS V. Faria et al. THIS QUERY FORM MUST
BE RETURNED WITH ALL PROOFS FOR CORRECTIONS …
Structure-function relationships in mammalian Histidine-Proline-Rich Glycoprotein
F Ronca, A Raggi – Biochimie, 2015
Histidine-proline-rich glycoprotein (HPRG), or histidine-rich glycoprotein (HRG), is a serum
protein that is synthesized in the liver and is actively internalis.
Fibromyalgia
[PDF] Adult attention-deficit and hyperactivity disorder and fibromyalgia: a case-control study
A Golimstok, MC Fernandez, MM Garcia Basalo – Neuro Open J, 2015
ABSTRACT Introduction: Fibromyalgia syndrome (FMS) is a disorder characterized by
widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues.
An association between attention deficit and fibromyalgia was reported. However, to our …
Fasting and rheumatic diseases (ahead of publication)
MH Jokar – Journal of Fasting and Health, 2015
… Predicting chronic symptoms after an acute “stressor”—lessons learned from 3 medical conditions.
Med Hypotheses 2004;63:653-8. 17-Chervin RD, Teodorescu M, Kushwaha R, et al. Objective
measures of disordered sleep in fibromyalgia. J Rheumatol 2009;36:2009-16. …
… —With treatment approaches for fibromyalgia evolving over the course of modern medicine, many clinicians are reviewing the Diagnosing and Treating Fibromyalgia: …
C Palsy, CPCLE Row
The pathophysiology of fibromyalgia includes central sensitization (amplification of pain in
the spinal cord via spontaneous nerve activity, expanded receptive fields, and augmented
stimulus responses), abnormalities of descending inhibitory pain pathways (dysfunction in …
[HTML] Select a Site
V Promise, VO Heritage, B Areas, L Diabetes…
Neuroscience covers both mental disorder and pain manifestations. Mental disorder covers Bipolar
Disorder, Schizophrenia,Depression and General Anxiety Disorder while pain includes Diabetic
neuropathy, Fibromyalgia and chronic pain. … 54th ed. Lange; 2015. Fibromyalgia. …
The measurement of bridging social capital in population health research
E Villalonga-Olives, I Kawachi – Health & Place, 2015
… capital (a combination of social resources that can be beneficial to a person’s physical health
and well-being), personal coping strategies, and additional personal and disease-related factors,
contribute to the functioning and quality of life (QoL) of fibromyalgia (FM) patients. …
Therapeutic Effects of the Mineral Waters from Copahue Spa
AM Monasterio, F Armijo, F Maraver – Copahue Volcano, 2015
… and chondrolysis, Fioravanti et al. (2011) reported: • A reduction in the levels of
circulating pros- taglandins E2 (PGE-2) and leukotriene B4 (LT-B4) in patients with
osteoarthritis or fibromyalgia. • Reductions in tumour necrosis …
Seven Steps to Choosing Joy!: Discover the Power of Your Inner Wisdom
L Ackles – 2015
DRUG DELIVERY CONJUGATES CONTAINING UNNATURAL AMINO ACIDS AND METHODS FOR USING
IR Vlahov, CP Leamon – US Patent 20,150,258,203, 2015
… any one of the preceding embodiments wherein the disease is selected from the group consisting
of arthritis, including rheumatoid arthritis and osteoarthritis, glomerulonephritis, proliferative
retinopathy, restenosis, ulcerative colitis, Crohn’s disease, fibromyalgia, psoriasis and ..