by admin | May 14, 2015 | Uncategorized
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
[PDF] Transscalene Brachial Plexu Approach for Brachial Plexus
SR Totawar – Age, 2015
… tchy action of the block, the block was converted to general anesthesia. If in case surg e effect
of the block wore off, rescue analgesia with intravenous ketamine given. … In the circumstance
of nesthesia. If in case surgery was unduly us ketamine given. …
Giuseppe D’Agostino1, 2*, Claudia Cristiano1, 2, 3, David J. Lyons2, Rita Citraro4, Emilio Russo4
C Avagliano, R Russo, GM Raso, R Meli, G De Sarro… – 2015
… pharmacological PPAR-α agonist treatment in mice improves behavior in a pharmacological
model of ketamine-induced behavioral dysinhibition and repetitive behavior in BTBR T+ tf/J mice. …
Keywords: lipids; nuclear receptor; ketamine; memory; neurodevelopmental disorders; …
[PDF] Efficacy conventional intersc approach Vs novel transscal of brachial plexus block
SR Totawar – 2015
… In the circumstance of inad anaesthesia. If in case surgery was undu intravenous
ketamine given. … If in case surgery was unduly prolonged and the effect of the block
wore off, rescue analgesia with intravenous ketamine given. …
Radiofrequency Ablation of the Pancreas: Protective Effect of Local Cooling Techniques
A Geranios, E Pikoulis, A Papalois, M Kontos… – The American Surgeon, 2015
… 1). Surgical Procedure The animals were anesthetized with ketamine (15–20 mg/kg) and
midazolam (0.5 mg/kg) in- tramuscularly and then intubated. The maintenance of anesthesia
was achieved by thiopental (3.5 mg/kg/hr) and fentanyl (15 mg/kg/hr). …
[HTML] Original Study Enhancement of Acute Tendon Repair Using Chitosan Matrix
E Melamed, BG Beutel, D Robinson – Am J Orthop, 2015
… Tikva, Israel. The rats were anesthetized with ketamine 90 mg/kg and xylazine 10
mg/kg, both administered intramuscularly, and anesthesia was prolonged as needed
with 2% isoflurane, administered by nose cone. The skin …
[PDF] Cyclosporine A Reduces Glial Scarring and Facilitates Functional Recovery Following Transient Focal Ischemia
HCS Abeysinghe, L Bokhari, GJ Dusting, C Roulston – J Neurol Neurophysiol, 2015
… food and water. Rats were anaesthetized using a mixture of Ketamine/Xylazine
(75 mg/kg: 10 mg/kg respectively ip) and maintained throughout surgery by inhalation
of isoflurane (95% oxygen and 5% isoflurane). A 23-gauge …
Antiseizure medications
S Sanders – Seizures in Dogs and Cats
… felbamate (FBM); ketamine (KET); lacosamide (LCM). Summary. … The uncommon drugs include
felbamate (FBM), ketamine (KET), lacosamide (LCM), and propofol (PRO). Some of the rarely
used drugs are carbamazepine, ethosuximide, and valproic acid. Get PDF (344K). …
Chronic neurokinin-1 receptor antagonism fails to ameliorate clinical signs, airway hyper-responsiveness or airway eosinophilia in an experimental model of feline …
M Grobman, A Graham, H Outi, JR Dodam, CR Reinero – Journal of Feline Medicine …, 2015
… 23 Briefly, ketamine (30 mg IV) was used as a premedicant, propofol was used for induction
(6 mg/kg) and maintenance (0.3 mg/kg/min), and cisatracurium (0.1 mg/kg IV of with additional
doses of 0.01–0.02mg/kg titrated to effect) was administered for neuromuscular blockade. …
[PDF] Evaluation of Anti-inflammatory and Analgesic Activities of Cymbopogon citratus in vivo-Polyphenols Contribution
R Garcia, JP Ferreira, G Costa, T Santos, F Branco… – Research Journal of …, 2015
… Ketamine (Ketalar, 7.7 mg kgG )1 was purchased from Parke-Davis, Pfizer (Seixal,
Portugal) Chlorpromazine (Largatil, 2.3 mg kgG )1 was purchased from
Rhône-Poulenc Rores, Laboratório Vitória SA (Amadora, Portugal). …
Acute neurokinin-1 receptor antagonism fails to dampen airflow limitation or airway eosinophilia in an experimental model of feline asthma
M Grobman, S Krumme, H Outi, JR Dodam… – Journal of Feline Medicine …, 2015
… 19 Briefly, ketamine (30 mg IV) was used as a premedicant, propofol was used for induction
(6 mg/kg) and maintenance (0.3 mg/kg/min), and cisatracurium (0.1mg/kg IV, with additional doses
of 0.01–0.02 mg/kg titrated to effect) was administered for neuromuscular blockade. …
Radiofrequency Ablation (RFA)
Radiofrequency Ablation of the Pancreas: Protective Effect of Local Cooling Techniques
A Geranios, E Pikoulis, A Papalois, M Kontos… – The American Surgeon, 2015
Pancreatic carcinoma is one of the commonest malignant diseases today and the majority of
patients are suitable for palliative treatment only. Radiofrequency ablation (RFA) has been
used extensively for the treatment of solid organ tumors but little is known on the efficacy …
Effects of renal denervation from the intima and the adventitia of renal arteries on renal sympathetic nerve activity in dogs: a comparative study
M Bai, C Yang, C Gao, X Wang, H Liu, Y Zhang, J Liu… – Cardiology, 2015
… A cardiac radiofrequency ablation catheter was then applied to ablate the adventitia from the
outside, also of 8 W or less and lasting up to 2 min each to obtain up to six ablations separated
both longitudinally and rotationally, which was the same as the ablation of renal …
[PDF] Laryngopharyngeal Reflux: a Syndrome that Mimics Asthma
M Merchant – Proceedings of UCLA Healthcare, 2015
… Surgical options include minimally invasive procedures such as radiofrequency ablation of the
lower esophageal sphincter as well as endoscopic Nissen Fundoplication, a procedure where
the surgeon wraps the stomach around the distal esophagus to create a tight valve. …
Helical DeNervation Ablation Catheter Apparatus
J Mogul – US Patent 20,150,126,992, 2015
… sympathetic nerves which run through the adventitia of the renal arteries using radiofrequency
(RF) energy … The catheter’s RF-ablation electrode(s) will then be deployed by movement of the
slider … the endoluminal, or inner arterial, surface of the artery in order to ablate the renal …
Method and Apparatus for Tissue Ablation
VK Sharma, H Jabs – US Patent 20,150,126,990, 2015
… can use one or more sources of infrared, electromagnetic, acoustic or radiofrequency energy
to … anal canal; engaging the targeted hemorrhoid by suctioning the hemorrhoid into the ablation
device; and, delivering the ablative agent to the hemorrhoid to ablate the hemorrhoid …
[PDF] N. Ayez1, EP van der Stok1, DJ Grünhagen1, J. Rothbarth1, E. van Meerten2, AM Eggermont3, C. 5 Verhoef1 6 7
DJ Grünhagen – 2015
… Local treatment was performed in 122 170 patients (47%) (surgery, radiofrequency ablation,
stereotactic radiotherapy), 112 patients (43%) had 171 palliative chemotherapy and 29 patients
(11%) received neither chemotherapy nor local treatment. 172 …
METHOD AND SYSTEM FOR SKIN TREATMENT
M Jurna, JA Palero, MR Horton – US Patent 20,150,126,913, 2015
… The modifier is configured to decrease the electrical impedance for the radiofrequency energy,
in particular … exploited concurrent with and/or directly subsequent to the burning and/or ablation
step and … as the aforementioned 70° C., and/or the laser is used to ablate skin portions …
Operative Techniques in Thoracic and Esophageal Surgery
M Hawn – 2015
Apparatus and Methods Related to Constrained Deployment of Cryogenic Balloons for Limited Cryogenic Abiation of Vessel Walls
B Kelly, J Kelly, G Kelly, B Mullins – US Patent 20,150,126,986, 2015
… As compared to ablation lesions formed via radiofrequency energy, cryotherapy typically utilizes
much less power … vessel wall and thus results in a smaller nominal treatment area/ablation pattern
than … In another embodiment (not shown), if it is desired to ablate more than half of …
[PDF] Long-term efficacy of radiofrequency ablation compared to surgical resection for the treatment of small hepatocellular carcinoma
X Bu, Z Ge, J Ma, S Guo, Y Wang, J Liu
Xiangyang Bu1,2*, Zhong Ge3*, Jian Ma4, Shanyuan Guo5, Yi Wang3, Jun Liu6 1Department
of Hepatobiliary Surgery, Qilu Hospital of Shandong University, Jinan 250021, China; 2Department
of Hepatobiliary Surgery, Qingdao Municipal Hospital, Qingdao 266011, China; …
Complex Regional Pain Syndrome (CRPS/RSD)
Evolving Chinese Restaurant Processes for Modeling Evolutionary Traces in Temporal Data
P Wang, C Zhou, P Zhang, W Feng, L Guo, B Fang – Advances in Knowledge …, 2015
… To model cluster branching over time, ECRP lets each cluster in current epoch form a Chinese
Restaurant Process (CRP) and uses the combination of cluster-specific CRPs as the prior for
clusters in the next epoch. … where ωt−1,k and ωt,O are the weights of CRPs. …
Practical Problems With Clinical Guidelines for Breast Cancer Prevention Based on Remaining Lifetime Risk
AS Quante, AS Whittemore, T Shriver, JL Hopper… – Journal of the National …, 2015
… To evaluate discrimination, we computed the overall AUC and we plotted case risk
percentiles (CRPs, also called standardized placement values) (21) for the subjects who
developed breast cancer within 10 years of recruitment (case patients). …
PIPERIDINE COMPOUND AND ITS USE IN PEST CONTROL
S Arimori – US Patent 20,150,126,516, 2015
… A01N43/58. Related US Applications: 20040209906, Composition comprising
ketanserin AND AN ALKANOYL L-CARNITINE FOR THE TREATMENT OF CRPS,
October, 2004, Cavazza et al. 20070249732, USE OF CERTAIN …
[PDF] News from the Patient Liaison Committee: The brave new world ‘How are pain services evolving–the impact on patients?’
A Chuter – Reltebon® Oxycodone Prolonged-release Tablets, 2015
Page 16. March 2015 Vol 13 No 1 l Pain News 13 Pain News 2015, Vol 13 (1)
13–14 © The British Pain Society 2015 News After months of planning by Geraldine
Granath, Colin Preece, Liz Killick, Austin Leach and Antony Chuter …
SYSTEMS AND METHODS FOR COMPOUND MOTOR ACTION POTENTIAL MONITORING WITH NEUROMODULATION OF THE PELVIS AND OTHER BODY …
KD Benson, VR Lucente, JR Miklos – US Patent 20,150,126,894, 2015
… Neuromodulation has also been used safely and effectively to help relieve chronic back pain,
pain from cancer and other nerve injuries, and pain from Complex Regional Pain Syndrome
(CRPS) and Reflex Sympathetic Dystrophy (RSD), greatly improving the quality of life for …
[PDF] EXPLORATION OF FACTORS ASSOCIATED WITH PATIENT ADHERENCE IN UPPER EXTREMITY REHABILITATION: A MIXED-METHODS EMBEDDED DESIGN
EV Smith-Forbes – 2015
… Multi-joint Fracture Multiple 0.0% 0.0% 0.0% 2.0% CRPS 0.0% 0.0% 0.0% 1.6% Nerve Injury
0.0% 0.0% 0.0% 1.2% … MCID= minimal clinical important difference, DRUJ= distal radio-ulnar
joint, CRPS = complex regional pain syndrome, ROC = receiver operator characteristics …
[PDF] Temperature Dependent Dielectric Model at 1.4 GHz for an Agricultural Soil Thawed and Frozen
VL Mironov, AY Karavaysky
… 0.513 The results of validation measurements for the soil CRPs are displayed in
Fig. … range. To obtain the error of the developed model, we correlated the predicted
CRPs with the ones especially measured for validation. In Fig. …
[PDF] A Bayesian A Bayesian Beta Markov Random Beta Markov Random Field Calibration of the Term structure of implied risk neutral densities densities
R Casarin, FR Casarin, F Leisen, GMGMG Molina…
Page 1. A Bayesian A Bayesian Beta Markov Random Beta Markov Random Field Calibration
of the Term structure of implied risk neutral densities densities Roberto Casarin, Fabrizio Roberto
Casarin, Fabrizio Leisen, German Molina German Molina German Molina, …
Fibromyalgia
[PDF] Heart rate turbulence analysis in female patients with fibromyalgia
O Solak, H ToktasIV – 2015
OBJECTIVE: Fibromyalgia is characterized by diffuse musculoskeletal pain and discomfort.
There are several reports regarding autonomic nervous system dysfunction in patients with
fibromyalgia. Heart rate turbulence is expressed as ventriculophasic sinus arrhythmia and …
[HTML] FIBROMYALGIA: CURABLE
ME Platt – Alternative Medicine, 2015
Abstract From a survival standpoint, the body always wants to make sure the brain has
enough fuel.[…] any time the body detects a low amount of fuel in the brain, it releases
adrenaline to raise sugar levels.[…] use of these methods often leads to a cure for …
[PDF] Association of Impaired Sleep Quality in Patients With Burning Mouth Syndrome: A Case-Control Study
F Arbabi-Kalati, NM Bakhshani, B Tahmtan… – 2015
… deprivation. Sleep deprivation can also lead to mood changes, insomnia and fatigue,
affecting pain sensation (2). Patients with known fibromyalgia have a lower noc- turnal
sleep quality compared to controls and have more insomnia …
Dizziness, Lightheadedness, and Syncope in a Patient with Type 2 Diabetes
S Paturi, JL Gilden, F FCP – Diabetes Case Studies: Real Problems, Practical …, 2015
Vagally mediated heart rate variability in headache patients—a systematic review and meta-analysis
J Koenig, DWP Williams, AH Kemp, JF Thayer – Cephalalgia, 2015
… capabilities (21). Lower vmHRV is reported in a variety of chronic painful conditions,
such as chronic neck pain (22), chronic pelvic pain (23), complex regional pain (24),
fibromyalgia (25,26) and irritable bowel syndrome (27). In …
Novel Therapeutic Uses of Mu-Opiate Receptor Peptides
TE Maione – US Patent 20,150,126,455, 2015
… pain. 16. The method, according to claim 1, used to reduce chronic noncancer pain
selected from pain associated with arthritis, neuropathy, low back pain, osteoarthritis,
fibromyalgia, headache, and diabetic neuropathy. 17. …
Brain-gut axis: gastroenterology-IBS
J Wright – The Specialist Forum, 2015
… to controls. Interestingly, this hypoalgesia was even greater in patients with concomitant
fibromyalgia, suggesting a commonality between these two symptom-driven diagnoses.
Anticipatory factors may also play a part. In experiments …
[PDF] A Pilot Study Measuring Outcomes of Managing Fascial Health for Individuals With Fibromyalgia
KB Segarra
Abstract This article examines the outcomes of managing fascial health for persons
diagnosed with fibromyalgia based on the protocol developed by the author, Dr. Kirstie
Bender Segarra, and implemented in a pilot study of five clients. The protocol was …
[PDF] The Somatosensory Amplification in Vitiligo and Chronic Urticaria Patients: A Controlled Study
M Sukan, F Maner – J Neurol Disord, 2015
… Amplification may be a pathogenic mechanism in certain specific amplification
disorders such as fibromyalgia and irritable bowel syndrome [9]. Some individuals
are generally more sensitive to bodily sensation than others. …
Psychotherapy and mental health as a psychological science discipline
HU Wittchen, S Härtling, J Hoyer – Verhaltenstherapie, 2015
… which behavioural factors play a significant role in the initiation, maintenance and rehabilitation,
such as cancer (eg [Fors et al., 2011]), cardiovascular disease (eg [Gulliksson et al., 2011]),
metabolic disease and obesity (eg [Grilo et al., 2012]), and fibromyalgia [Kashikar-Zuck et …
by admin | May 5, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Ketamine-A Narrative Review of Its Uses in Medicine.
BM Radvansky, S Puri, AN Sifonios, JD Eloy, V Le – American Journal of Therapeutics, 2015
One of the most fascinating drugs in the anesthesiologist’s armament is ketamine, an N-
methyl-D-aspartate receptor antagonist with a myriad of uses. The drug is a dissociative
anesthetic and has been used more often as an analgesic in numerous hospital units, …
Acute administration of ketamine inhibited stress induced pro-inflammatory cytokines in hippocampus of rats
G Unal, G Terzioglu, C Sahin, GY Demirel, F Aricioglu – Bulletin of Clinical …, 2015
Objective: Major depression is a complex and devastating disease which one-third of
patients still do not respond to current treatments. It has been demonstrated that there is a
correlation between high levels of plasma cytokines such as IL-1β, IL-6, IL-18 and TNF-α …
The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology.
GS Aylan, N Sarper, U Demirsoy, E Zengin, E Çakmak – Turkish journal of …, 2015
OBJECTIVE: The aim of this study is to investigate the efficacy and safety of sedoanalgesia
performed outside the operating room by pediatricians trained in advanced airway
management and life support. MATERIALS AND METHODS: Midazolam and ketamine …
[HTML] Alpha-lipoic acid alone and combined with clozapine reverses schizophrenia-like symptoms induced by ketamine in mice: Participation of antioxidant, nitrergic and …
GS Vasconcelos, NC Ximenes, CNS de Sousa… – Schizophrenia Research, 2015
Abstract Oxidative stress has important implications in schizophrenia. Alpha-lipoic acid
(ALA) is a natural antioxidant synthesized in human tissues with clinical uses. We studied
the effect of ALA or clozapine (CLZ) alone or in combination in the reversal of …
Low Dose Ketamine Infusion For Managing Acute Pain
M Yetim, S Tekindur, Y Emrah Eyi – The American Journal of Emergency Medicine, 2015
Dear Editor, We read with great interest the article “Short (low-dose) ketamine infusion for
managing acute pain in the ED: case-report series” written by Goltser et al (1). We believe
that this original study provides a new and insightful approach to pain management in …
[PDF] Symptomatic remission and hippocampus volume in schizophrenia
PT Chang, JF Lirng, YH Chou – Bulletin of Clinical Psychopharmacology, 2015
… 1):S146-S7 [Abstract:0577] Neuroimaging in psychiatry Alterations in resting state electrocortical
network oscillations, schizophrenia-like symptoms and their relationships induced with the
administration of the NMDA receptor antagonist ketamine in human volunteers …
G535 (P) The development and implementation of a policy promoting parental (patient) involvement in escalation of clinical care
MA Webster, C Haines, J Fraser – Archives of Disease in Childhood, 2015
… www.midstaffspublicinquiry.com/report (accessed 28 Nov 2014) G536(P) THE CHALLENGES
OF SETTING UP A KETAMINE SEDATION SERVICE IN THE PAEDIATRIC ED – LEARNING
LESSONS AND EFFECTING CHANGE 1E Dewhirst, 1C Whitehouse, 2T Waterfield. …
[PDF] Eyes tell the psychopathology: preliminary findings
H Balibey, C Basoglu, A Ates, A Algul, R Tutuncu… – Bulletin of Clinical …, 2015
… On the other hand, the behavioral and pharmacological effects of the noncompetitive
N-methyl-D-aspartate (NMDA) receptor antagonist ketamine have been used to study
important aspects of psychotomimetic action in humans. …
Adjunctive Use of Ceftriaxone and Sodium Valproate in the Management of Tetanus: A Case Report and Literature Review
S Oriaifo, N Oriaifo, M Oriaifo, E Okogbenin, E Omogbai – Journal of Biology, …, 2015
… immune globulin. Control of spasms was mainly by the use of the GABAergic-
enhancing drugs diazepam and sodium valproate combined with the use of the
anti-excitotoxics magnesium sulphate and ketamine. The introduction …
PyBidine–NiCl2-Catalyzed Asymmetric Addition of Alcohols and Peroxides to Isatin-Derived Ketimines
T Arai, K Tsuchiya, E Matsumura – Organic Letters, 2015
… adduct (27%, 80% ee). The formation of the chiral N,O-acetal inspired us to optimize
the reaction conditions for the addition of methanol to an isatin-derived
N-Boc-ketamine (1a), as shown in Table 1. Table 1. Optimization of …
Radiofrequency Ablation (RFA)
Radiofrequency Ablation for Atrial Fibrillation: Trends in Patients, Clinical Outcomes, and Resources Among Medicare Beneficiaries from Fiscal Year 2010 to Fiscal …
MR Reynolds, AD Kugelmass, DJ Cohen, PP Brown… – … : Cardiovascular Quality and …, 2015
Abstract Introduction: The objective of this analysis was to report four year trends among
Medicare beneficiaries (MB) undergoing Radiofrequency Ablation (RFA) to treat Atrial
Fibrillation (AF). Methods: This retrospective study examined both the Medicare Provider …
Systematic review and meta-analysis of perinatal outcomes following radiofrequency ablation and bipolar cord occlusion in monochorionic pregnancies
K Gaerty, RM Greer, S Kumar – American Journal of Obstetrics and Gynecology, 2015
Objective The aim of this study was to analyse perinatal outcomes following selective
reduction in monochorionic pregnancies using either radiofrequency ablation (RFA) or
bipolar cord occlusion (BCO). Study Design This was a systematic review and meta- …
Sublobar Resection, Radiofrequency Ablation or Radiotherapy in Stage I Non-Small Cell Lung Cancer
S Safi, G Rauch, J Kunz, T Schneider, M Bischof… – Respiration, 2015
Background: The best therapy for patients with stage I non-small cell lung cancer (NSCLC)
who are medically unfit for lobectomy or prefer not to undergo surgery has not yet been
demonstrated. Objectives: We analyzed data from our prospective database to evaluate …
The efficacy of radio-frequency ablation for metastatic lung or liver tumors of male germ cell tumors as an alternative minimally invasive therapy after salvage …
Y Naya, T Nakamura, M Oishi, T Ueda, H Nakanishi… – International Journal of …, 2015
… Okuma et al. [14] reported that tumors under 20 mm in size can be completely ablated in lung
tumor. … Cancer 3:1409–1419 7. Curley SA, Izzo F, Delrio P et al (1999) Radiofrequency ablation
of unresectable primary and metastatic hepatic malignancies. Results in 123 patients. …
Metastastectomy for metachronous pulmonary and hepatic metastases from nasopharyngeal carcinoma: Report of 6 cases and review of the literature
SJM Lim, NG Iyer, LL Ooi, HN Koong, A Chung, HK Tan… – Head & Neck, 2015
… not prevent disease progression in the long term. Surgery and radiofrequency ablation have … ten
patients who underwent radiofrequency ablation +/- adjuvant chemotherapy had a median survival
period of 77.1 months compared to 32.4 months in another ten patients who only …
[HTML] Lobulated Enhancement Evaluation in the Follow-Up of Liver Metastases Treated by Stereotactic Body Radiation Therapy
H Jarraya, P Borde, X Mirabel, O Ernst, T Boulanger… – International Journal of …, 2015
… have limitations for the evaluation of targeted therapies; for example, imatinib for gastrointestinal
stromal tumors (GIST) and bevacizumab for colorectal liver metastasis 8, 9 and 10 or other local
treatments, such as lung tumor SBRT (11), liver radiofrequency ablation (12), and …
Percutaneous microwave ablation of thyroid nodules: effects on thyroid function and antibodies
K Heck, C Happel, F Grünwald, H Korkusuz – International Journal of Hyperthermia, 2015
… The results demonstrated that in all 30 sessions the complete volume of the 34
nodules could be ablated. The treatment … al. Radiofrequency ablation of benign thyroid
nodules: Safety and imaging follow-up in 236 patients. Eur …
Current state of the treatment of perforating veins
ED Dillavou, M Harlander-Locke, N Labropoulos… – Journal of Vascular Surgery: …, 2015
… Table II. Technical success of radiofrequency ablation (RFA), endovenous laser ablation (EVLA),
and ultrasound-guided foam sclerotherapy (UGFS). Primary author (year), Perforator treatment
modality, No. … 14, 15, 18 and 26. Radiofrequency ablation (RFA). …
Irreversible Electroporation of the Pancreas Is Feasible and Safe in a Porcine Survival Model.
S Fritz, CM Sommer, D Vollherbst, MF Wachter… – Pancreas, 2015
… From a histopathological point of view, the ablated area was character- ized by cellular eosinophila …
The ability of IRE to ablate undesirable tissue near large blood vessels and damageable … of the
electric field to which the tissue is exposed.13 Radiofrequency ablation has been …
An Analysis of Patients Transferred to a Tertiary Oncological Intensive Care Unit for Defined Procedures
S Kamat, S Chawla, P Rajendram, SM Pastores… – American Journal of Critical …, 2015
Skip to main page content. …
Complex Regional Pain Syndrome (CRPS/RSD)
Two Virtual Reality Pilot Studies for the Treatment of Pediatric CRPS
AS Won, CA Tataru, CM Cojocaru, EJ Krane… – Pain Medicine, 2015
… Letter to the Editor. Two Virtual Reality Pilot Studies for the Treatment of Pediatric CRPS. … How
to Cite. Won, AS, Tataru, CA, Cojocaru, CM, Krane, EJ, Bailenson, JN, Niswonger, S. and Golianu,
B. (2015), Two Virtual Reality Pilot Studies for the Treatment of Pediatric CRPS. …
A dynamic PUF anti-aging authentication system based on restrict race code
B Li, S Chen – Science China Information Sciences, 2015
… Based on the CRP mechanism, the PUF circuit can produce chip-unique responses when
challenges are applied to it and stored in the database by the way of CRPs. (2) Authentication. …
The expected data in the database are called CRPs in paper. …
Increased prevalence of two mitochondrial DNA polymorphisms in functional disease: Are we describing different parts of an energy-depleted elephant?
RG Boles, EA Zaki, JR Kerr, K Das, S Biswas… – Mitochondrion, 2015
… Herein, we tested for these variants in chronic fatigue, CRPS, SIDS and depression. … CVS = cyclic
vomiting syndrome, Fxn abd pain = functional abdominal pain (a common pediatric functional
syndrome), IBS = irritable bowel syndrome, CRPS = complex regional pain syndrome. …
[HTML] TURAN and EVAN Mediate Pollen Tube Reception in Arabidopsis Synergids through Protein Glycosylation
H Lindner, SA Kessler, LM Müller, H Shimosato-Asano… – 2015
… Abbreviations:: ConA, Concanavalin A; CRPs, cysteine-rich polypeptides; CrRLK1L, Catharanthus
roseus receptor-like kinase 1-like subfamily; DAE, days after emasculation; DAP, days after
pollination; DAPI, 4′,6-diamidino-2-phenylindole; DEFL, defensin-like protein; Dol-P …
Facilitated spinal neuropeptide signaling and upregulated inflammatory mediator expression contribute to post-fracture nociceptive sensitization.
X Shi, T Guo, T Wei, W Li, DJ Clark, WS Kingery – PAIN, 2015
… neuropeptide-dependent nociceptive and inflammatory changes in the hindlimbs of rats similar
to those seen in complex regional pain syndrome (CRPS). Inflammatory changes … inflammatory
mediators contributing to nociceptive sensitization in a rodent fracture model of CRPS. …
Ketamine-A Narrative Review of Its Uses in Medicine.
BM Radvansky, S Puri, AN Sifonios, JD Eloy, V Le – American Journal of Therapeutics, 2015
… pain clinics, and in the prehospital realm. It has been used to treat postoperative pain, chronic
pain, complex regional pain syndrome (CRPS), phantom limb pain (PLP), and other neuropathic
conditions requiring anal- gesia. … CRPS has remained a difficult-to-treat entity. …
Trends in Coronary Revascularization Procedures among Medicare Beneficiaries between Fiscal Years 2010 and 2013
A Kugelmass, MR Reynolds, DJ Cohen, PP Brown… – … : Cardiovascular Quality and …, 2015
… Mortality rates were highest and increasing for MBs presenting with STEMI across all procedures.
Conclusions: The overall volume of CRPs among MBs is declining and more MBs are presenting
with an AMI, and overall mortality rates are increasing year over year. …
CORD STIMULATIONS IN PATIENTS WITH COMPLEX REGIONAL PAIN SYNDROME: A RANDOMIZED PLACEBO CONTROLLED TRIAL
N Kriek, J Groeneweg, D Stronks, F Huygen
… N. Kriek, J. Groeneweg, D. Stronks, F. Huygen Center for pain management, Erasmus MC,
Rotterdam, The Netherlands Objectives: Spinal cord stimulation (SCS) is an effective invasive
therapy to treat neuropathic pain states including complex regional pain syndrome (CRPS). …
[HTML] Diagnostic value of C-reactive protein to rule out infectious complications after major abdominal surgery: a systematic review and meta-analysis
SL Gans, JJ Atema, S van Dieren, BG Koerkamp… – International Journal of …, 2015
… The posttest odds were calculated by multiplying the pretest odds with the positive and
negative LR. Posttest probabilities for a high and a low CRPs were calculated and presented
in a graph for pretest probabilities across the range of 0 to 100 %. …
[HTML] World congress comes to you 7: Yes we can (control chronic pain)
V Bellan
… If you want more information on CRPS you might find what we know about CRPS helpful as
well as these resources by the Royal College of Physicians. You can also read recent research
published by the team and browse through our CRPS blog articles. …
Fibromyalgia
Factors Associated With Time to Diagnosis in Fibromyalgia
G Chodick, D Weitzman, Y Bar-On, V Shalev, H Amital – Journal of Patient-Centered …, 2015
Background/Aims: The diagnosis of fibromyalgia, a chronic debilitating disorder, is
complicated and affected by various factors of the patient and the caregiver. The objectives
of this study were to investigate the time passing from initial complaints to diagnosis and to …
[PDF] Central Sensitization Syndrome and the Initial Evaluation of a Patient with Fibromyalgia: A Review
KC Fleming, MM Volcheck – Rambam Maimonides Med J, 2015
ABSTRACT In both primary care and consultative practices, patients presenting with
fibromyalgia (FM) often have other medically unexplained somatic symptoms and are
ultimately diagnosed as having central sensitization (CS). Central sensitization …
Does low bone density influence symptoms and functional status in patients with fibromyalgia? Observations from rural South India
AS Babu, FM Ikbal, MS Noone, AN Joseph, D Danda – International Journal of …, 2015
Results Low BMD was seen in 81.6%(129/158) of the persons screened. FMS was seen in
37/158 persons, of which 31/37 (83.7%) had low BMD. Conclusion FMS with low bone
density leads to higher levels of pain and a poorer QoL compared to those without FMS. …
[PDF] Walking as physical exercise in Fibromyalgia: An elicitation study from the Theory of Planned Behavior
MÁ Pastor, S López-Roig, Y Sanz, C Peñacoba – anales de psicología, 2015
Abstract: This study is the first phase of the formative research recommended in the Theory
of Planned Behavior for the development of an intervention. Our aims are to identify modal
beliefs about the performance of an exercise pattern in people with fibromyalgia, to test …
… advances in spinal cord and brainstem fMRI provide an unprecedented view of human pain processing and alterations to pain mechanisms in fibromyalgia
R Bosma – 2015
Abstract: Functional MRI of the human spinal cord and brainstem has tremendous potential
to enhance our basic understanding of healthy subcortical function, and impact our ability to
accurately diagnose and treat injury and disease. Despite this potential, there are many …
Understanding High Blood Pressure
S Aziz – 2015
Overcoming Low Self-Esteem with Mindfulness
D Ward – 2015
[HTML] Efficacy and processes of change in acceptance and commitment therapy for chronic pain
M Kemani – 2015
… The first trial utilized a wait-list control condition and included women with fibromyalgia (Study
I). Assessments were done pre- and post-treatment and at 3-month follow-up. … Acceptance and
commitment therapy for fibromyalgia: A randomized controlled trial. …
[PDF] Evaluation of psychiatry consultations requested for inpatients in a university hospital
H Mayda, HI Guzel, Y Gorucu, E Bagcioglu – Bulletin of Clinical Psychopharmacology, 2015
… [Abstract:0282] Psychosomatic disorders Metacognitive evaluation in patients with fibromyalgia
syndrome … In this study, we tested the assumption that patients with Fibromyalgia Syndrome (FMS)
experience more metacognitive thoughts compared to healthy individuals. …
[PDF] Investigation of state and trait anxiety levels among pharmacy students in TRNC
YH Balcıoglu, E Duran – Bulletin of Clinical Psychopharmacology, 2015
… Bulletin of Clinical Psychopharmacology 2015;25(Suppl. 1):S93-S4 [Abstract:0452] Anxiety,
stress, and adjustment disorders Angiotensin-converting enzyme and
methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome …
by admin | Apr 30, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Rapid antidepressant Action and Restoration of Excitatory Synaptic Strength after Chronic Stress by Negative Modulators of alpha5-containing GABAA Receptors.
J Fischell, AM Van Dyke, MD Kvarta, TA LeGates… – … : official publication of the …, 2015
… The NMDA receptor antagonist ketamine exerts a rapid antidepressant action, but
has troubling side-effects. We hypothesized that negative allosteric modulators of
GABAA receptors would exert similar effects on brain activity …
Temporal evoltion on MRI of successful treatment of rabies
A Lu, P Shah, P Shen, P Lee, AE Nidecker… – Clinical Imaging, 2015
… Her treatment regimen came to be known as the “Milwaukee protocol” [1]. Briefly, the
protocol consists of using a sedative agent such as ketamine, midazolam, propofol, or
a combination to place the patient in a medically induced coma. …
[PDF] A Gelatin-Based Prophylactic Sealant for Bowel Wall Closure, Initial Evaluation in Mid-rectal Anastomosis in a Large Animal Model
Y Kopelman, Y Nir, Y Siman-Tov, B Person, O Zmora – J Gastrointest Dig Syst, 2015
… Preemptive analgesia (intramuscular Dipyron 1 gr) was given to all any amounts prior to surgery.
The animals were anesthetized with a combination of Ketamine 22 mg/mL and Xylazine injection
(Apectrum Chemicals and Laboratory Products, Gardena, California) 1 mg/kg IM. …
[PDF] The optimal fitting model for aging-related receptive field size curve of macaque V1 neurons
J Cui, H Ding, L Wang, J Qiang – … on Mechatronics, Electronic, Industrial and Control …, 2015
… of 28 years. An initial ophthalmological examination was performed under ketamine
(100 mg/kg im, Ketalar, Parke-Davis, Morris Plains, NJ, USA) anesthesia to screen
for monkeys with ocular pathology. B. Visual Stimulation …
[PDF] Preventing Testicular Damage in Genital Burns With Cooling: An Experimental Study
AE Abalı, H Özdemir
… The sham group (S group) consisted of 10 healthy testes. In this group, rats were anesthetized
with an intraperitoneal injection of 100 mg/kg ketamine hydrochloride (Alfamine 10%, Alfasan,
Holland) and 10 mg/kg … Animals were killed by high-dose ketamine HCl. …
[PDF] JAMES A. McNAMARA, JR., DDS, Ph. DT
T KURODA
… Page 2. Ketamine & Phencyclidine . . . … Dosage, prepared according to levels
recommended by other investigators-fit10:11 was as fol- lows: phencyclidine HCl,
1.5 ngkg. of body weight (intramuscular); ketamine HCI, 25 mgjkg. …
Fine-scale genetic structure of the ringtail (Bassariscus astutus) in a Sky Island mountain range
RC Lonsinger, RM Schweizer, JP Pollinger, RK Wayne… – Journal of Mammalogy, 2015
… Traps were baited with dry cat food and either loganberry paste or sardines. Captured ringtails
were anesthetized using a mixture of medetomidine hydrochloride (50 µg/kg) and ketamine
hydrochloride (5mg/kg) injected intramuscularly (Orion Corporation, Espoo, Finland). …
[PDF] Evaluation of the Effect of Alfalfa Extract on Breast Cancer
F Nabatchian, SMH Aghoosi, A Mordadi, F Khodaverdi – J. Appl. Environ. Biol. Sci, 2015
… normal saline. In the solution, the tumor was cut into 3 mm2 pieces. Then, the mice
in the first and second groups were anesthetized with intraperitoneal injection of
ketamine (10 mg/kg) and xylene (5 mg/kg). The tumor pieces …
Effects of light pollution on seasonal estrus and daily rhythms in a nocturnal primate
T LeTallec, M Théry, M Perret – Journal of Mammalogy, 2015
… Ltd, Saint-Paul, Minnesota) previously implanted in the visceral cavity under general anesthesia
and under veterinary supervision (Diazepam-Valium: 1mg/100g, subcutaneous injection; Ketamine
hydrochloride-Imalgen: 10mg/100g, intraperitoneal injection; postoperative …
[PDF] Evaluation of Cissampelos pareira root for antifertility activity
J Samanta, S Bhattacharya, AC Rana – Journal of Pharmacy Research Vol, 2015
… from D1 pregnancy. On day 12th day (D12) all the rats of control and treated group
were anaesthetized with normal dose of ketamine-xylazine anaesthesia15 and
laparotomized to count the no. of implants of each rat. 2.3.6. Effectsof …
Radiofrequency Ablation (RFA)
[HTML] Transcatheter embolization therapy in liver cancer: an update of clinical evidences
YXJ Wáng, T De Baere, JM Idée, S Ballet – Chinese Journal of Cancer Research, 2015
… 2-4). For the treatment of early stage HCC, curative therapies including liver transplantation,
hepatic resection, and radiofrequency ablation (RFA) are … coagulative necrosis of both the tumor
and a rim of surrounding parenchymal tissue producing a margin of ablated non-tumoral …
CATHETER WITH ATRAUMATIC TIP
ES Olson, JV Kauphusman, LK Nemec, TT Tegg – US Patent 20,150,112,331, 2015
… According to at least one medical study (See, eg, Ikeda et al., Radiofrequency Ablation Catheter
with Contact Force Sensor Predicts Lesion Size and Incidence of Steam Pop in the Beating Canine
Heart, Conference Proceedings of the Hearth Rhythm Society, May 2008 and …
ELECTRICAL STIMULATION OF THE CAROTID ARTERY
I Gillbe – US Patent 20,150,112,359, 2015
… or bodies without heating the tissues to a temperature at which they are ablated such that … the
RF energy delivered is of a non-thermal nature, so that ablation and possible … As previously
described, pulsed radiofrequency is employed for this purpose; comprising short bursts of …
METHOD TO REDUCE SENSE OF TASTE AND FOOD INTAKE
H Li – US Patent 20,150,112,326, 2015
… To ablate the subsurface tissue without ablating the surface tissue of the mouth, a room … During
a heat induced ablation with fluid cooling, ablation head and the tissue surface in … delivered into
it from an energy source such as ultrasound, microwave, and radiofrequency current. …
MODULATION OF NERVES INNERVATING THE LIVER
BR Azamian, JA Coe, SB Vafai – US Patent 20,150,112,332, 2015
… In some embodiments, the neuromodulation catheter is a radiofrequency (RF) ablation catheter
comprising … about substantially 180 degrees of the vessel circumference to ablate in a … In some
embodiments, other patterns of ablation electrode movement (regardless of inherent …
BALLOON CATHETERS WITH FLEXIBLE CONDUCTING WIRES AND RELATED METHODS OF USE AND MANUFACTURE
MR Willard, DC Sutermeister, KR Larson, TA Ostroot… – US Patent 20,150,112,328, 2015
… Sympathetic nerve ablation device 12 may be used to ablate nerves (eg, renal nerves) disposed
adjacent to the kidney K (eg, renal nerves … Sympathetic nerve modulation device 12 may be
configured to deliver ablation energy, for example, radiofrequency energy, to a target …
Current Control Methods and Systems
H Cadouri – US Patent 20,150,112,321, 2015
… an energy field to a target site in the renal artery (eg, via radiofrequency ablation) have been … above
45° C. (or above 60° C. in other cases) may induce thermal ablation of the … In some patients, it
may be desirable to achieve temperatures that thermally ablate the target neural …
DIAPHRAGM ENTRY FOR POSTERIOR SURGICAL ACCESS
SD Fleischman, R Neubert, EW Rogers – US Patent 20,150,112,145, 2015
… Atrial fibrillation surgery involving radiofrequency, DC, microwave, ultrasound, laser or other
modes of thermal … of focusing energy into local areas spaced at known distances from the ablation
device (in … tissue in the ventricles from the diaphragm) are used to ablate the imaged …
[PDF] ASRA/ESRA/INS/AAPM/WIP/NANS guidelines for interventional spine and pain procedures in patients on antiplatelets and anticoagulants
S Narouze, HT Benzon, D Provenzano, A Buvanendran…
… C, cervical; T, thoracic; L, lumbar; S, sacral; MBNB, medial branch nerve block; RFA,
radiofrequency ablation *Patients with high risk for bleeding undergoing low or intermediate
risk procedures should be treated as internmediate or high risk repectively. …
SYSTEM AND METHOD FOR TREATING URINARY TRACT DISORDERS
U Eshel – US Patent 20,150,112,413, 2015
… transurethral microwave thermotherapy (temperatures over 46 degrees Celsius that cause tissue
ablation to exposed … that the higher level of heat in the surrounding non-ablated tissue either … It
includes a catheter with a sheathed radiofrequency antenna, surrounded by a flow of …
Complex Regional Pain Syndrome (CRPS/RSD)
What is the maximum safe tourniquet time in elective upper limb surgery?
N Sawant, GEB Giddins – Journal of Hand Surgery (European Volume), 2015
… Two patients developed chronic regional pain syndrome type 1 (CRPS 1). In one patient this
was noticed 4 weeks following complex rheumatoid surgery. The tourniquet time was 2 hours
4 minutes and there was no immediate post-operative pain or distal paraesthesia. …
RODENT RUN
MJ Dixon, PM Taylor, B Dixon – US Patent 20,150,107,525, 2015
… [2] Millecamps, Laferrière, Ragavendran, Stone, Coderre: “Role of peripheral endothelin receptors
in an animal model of complex regional pain syndrome type 1 (CRPS-I)” J Pain, volume 151
(2010) pages 174-183; [3] Ugo Basile Leaflet for Von Frey Hairs (with grid) Cat. No. …
Using Computing with Words for Managing Non-cooperative Behaviors in Large Scale Group Decision Making
FJ Quesada, I Palomares, L Martínez – Granular Computing and Decision-Making, 2015
… sufficiently to reach the solution made. In order to overcome this drawback, Consensus
Reaching Processes (CRPs) were introduced as an additional phase in the resolution
process for GDM problems [17]. In a CRP, experts try …
The Parturient With Implanted Spinal Cord Stimulator: Management and Review of the Literature
AC Young, TR Lubenow, A Buvanendran – Regional Anesthesia and Pain Medicine, 2015
… Complex regional pain syndrome (CRPS) is neuropathic pain syndrome that is more common
in women, with some studies showing a higher prevalence among women aged 25 to 50
years. … Patient 3 suffered from CRPS of the right upper extremity. …
Decision Makers’ Opinions Changing Attitude-Driven Consensus Model under Linguistic Environment and Its Application in Dynamic MAGDM Problems
B Dutta, D Guha – Granular Computing and Decision-Making, 2015
… Based on the concept of soft consensus, vari- ous consensus reaching processes
(CRPs) have been designed in the literature [22]. The existing CRPs for solving GDM
problems can be classified in two categories: static consensus …
Peripheral Nerve Stimulationperipheral nerve stimulation
AS Hanna – Anatomy and Exposures of Spinal Nerves, 2015
… Download Chapter (482 KB). Abstract. Peripheral nerve stimulation is an off-label use of spinal
cord stimulators. It is used for intractable pain in a peripheral nerve distribution, refractory to
medical management, especially with complex regional pain syndrome (CRPS ). …
[HTML] External Fixation and Adjuvant Pins Versus Volar Locking Plate Fixation in Unstable Distal Radius Fractures: A Randomized, Controlled Study With a 5-Year Follow- …
JH Williksen, T Husby, JC Hellund, HD Kvernmo… – The Journal of Hand …, 2015
… At the 5-year follow-up, 3 patients had died, 1 (with an extensor pollicis longus rupture) had moved
abroad, and 2 (1 patient with complex regional pain syndrome [CRPS]) withdrew from the study. …
Carpal tunnel syndrome, 2, 1. CRPS, 0, 1. Extensor tendon synovitis, 0, 5. …
Complex regional pain syndrome type I: a comprehensive review
M Bussa, D Guttilla, M Lucia, A Mascaro, S Rinaldi – Acta Anaesthesiologica …, 2015
… Background. Complex regional pain syndrome type I (CRPS I), formerly known as reflex
sympathetic dystrophy (RSD), is a chronic painful disorder that usually develops after a
minor injury to a limb. … Pathophysiological mechanisms of CRPS I. …
Phenotype-Specific Diagnosis of Functional (Psychogenic) Movement Disorders
AJ Espay, AE Lang – Current Neurology and Neuroscience Reports, 2015
Page 1. MOVEMENT DISORDERS (M OKUN, SECTION EDITOR) Phenotype-Specific
Diagnosis of Functional (Psychogenic) Movement Disorders Alberto J. Espay1,3 & Anthony
E. Lang2 © Springer Science+Business Media New York 2015 …
[PDF] Time-consistent calibration of short-term regional wind power ensemble forecasts
S SPäTH, L VON BREMEN, C JUNk, D HEINEMANN – 2015
… For minimum score esti- mation, we use the continuous ranked probability score (crps). … For
a forecast cumulative distribution function (cdf) Fp(x) and the verifying obser- vation y, the crps
can be calculated as: crps(Fp,y) = ∞ ∫ − Fp(x) − Θ(x − y) ]2 dx (4.4) …
Efficient production of a correctly folded mouse α-defensin, cryptdin-4, by refolding during inclusion body solubilization
S Tomisawa, Y Sato, M Kamiya, Y Kumaki, T Kikukawa… – Protein Expression and …, 2015
… The mouse Paneth cell α-defensins, termed cryptdins (Crps) 1 , are secreted into the lumen of
the small intestinal crypts in response to exposure to bacteria or bacterial antigens [6]. Among
the known isoforms, cryptdin-4 (Crp4) has the most potent antimicrobial activity [7 …
[PDF] Erythrocyte Sedimentation Rate, C-Reactive Protein and Procalcitonin in Infections of the Spine and Infections in Spinal Cord Injury Patients
JAL Buensalido, MP Reyes – Open Infectious Diseases Journal, 2015
… One study reported a mean CRP of 3 mg/L in paraplegics, while a mixed paraplegia/tetraplegia
study that excluded patients with CRPs >10 mg/L, also showed a mean of 3 mg/L. Another group
noted that mean CRP level was 38 mg/L, or 27% higher, in SCI versus non-SCI …
Fibromyalgia
The role of sleep in pain and fibromyalgia.
EH Choy – Nature reviews. Rheumatology, 2015
Fibromyalgia is a common cause of chronic widespread pain, characterized by reduced
pressure pain thresholds with hyperalgesia and allodynia. In addition to pain, common
symptoms include nonrestorative sleep, fatigue, cognitive dysfunction, stiffness and mood …
Nonpharmacological Treatments of Insomnia for Long-Term Painful Conditions: A Systematic Review and Meta-analysis of Patient-Reported Outcomes in …
NK Tang, ST Lereya, H Boulton, MA Miller, D Wolke… – Sleep, 2015
… This study evaluated the effect of nonpharmacological sleep treatments on
patient-reported sleep quality, pain, and well-being in people with long-term cancer
and non-cancer (eg, back pain, arthritis, fibromyalgia) pain conditions. …
COMPOSITIONS AND METHODS FOR TREATING INTESTINAL HYPERPERMEABILITY
S Hoffman – US Patent 20,150,111,878, 2015
… Abstract: The present invention provides methods, compositions, and kits for treating intestinal
hyperpermeability in a subject in need thereof, including underlying diseases such as diabetes,
autism, fibromyalgia, inflammatory bowel disease (IBD), graft versus host disease …
American College of Lifestyle Medicine Expert Panel Discussion Treat the Cause: Evidence-Based Practice*
JM Rippe, M Greger, DL Katz, JH Kelly, M Moore… – American Journal of …, 2015
… Following this strategy, I am fostering clinical evaluation of coaching for fibromyalgia,
for which there is no good treatment other than exercise. However, it has taken 10
years to get to the place where we have enough coaches …
Whole body vibration training in patients with COPD A systematic review
R Gloeckl, I Heinzelmann, K Kenn – Chronic Respiratory Disease, 2015
… Abstract. In recent years, several studies have shown that whole body vibration training (WBVT)
may be a beneficial training mode in a variety of chronic diseases and conditions such as
osteoporosis, fibromyalgia, multiple sclerosis, or chronic low back pain. …
[PDF] Fibromyalgia Syndrome AmongIraqi Patients with Systemic Lupus Erythematosus: A Case Control Study
ZS Al-Rawi, HAJ Badran, FI Gorial
Abstract: Objective: To determine the prevalence of fibromyalgia syndrome (FMS) among
Iraqi patients with systemic lupus erythematosus (SLE) and its association with disease
activity. Patients and methods: This case control study included 100 patients with SLE and …
[PDF] Quality of life, sense of coherence and experiences with three different treatments in patients with psychological distress in primary care: a mixed-methods study
T Arvidsdotter, C Taft, B Marklund, S Kylén – BMC Complementary and Alternative …, 2015
… More detailed data on the procedure are reported elsewhere [48]. The patients had a primary
diagnosis of depression, anxiety or panic disorders, severe stress, somatic symptoms/pain
(including irritable bowel syndrome, fibromyalgia, migraine, fatigue) or sleep disorders. …
SULFUR-CONTAINING BICYCLIC COMPOUND
N Shiraishi, H Hoshii, W Hamaguchi, E Honjo… – US Patent 20,150,111,876, 2015
… containing bicyclic compound having a PAM action of GABA B , and it use for preventing
and/or treating schizophrenia, CIAS, cognitive impairment, fragile X syndrome, autism spectrum
disorder, spasticity, anxiety disorder, substance addiction, pain, fibromyalgia, or Charcot …
TOPICAL REGIONAL NEURO-AFFECTIVE THERAPY
R Aung-din – US Patent 20,150,111,930, 2015
… respective receptors. They are indicated for such diverse and seemingly different
conditions as: focal onset seizures, post-herpetic neuralgia, diabetic peripheral
neuropathy, fibromyalgia, anxiety, and drug withdrawal syndromes. The …
Associations between the functional CD40 rs4810485 G/T polymorphism and susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis
YH Lee, SC Bae, SJ Choi, JD Ji, GG Song – Lupus, 2015
[HTML] Response to Vitamin B12 and Folic Acid in Myalgic Encephalomyelitis and Fibromyalgia
B Regland, S Forsmark, L Halaouate, M Matousek… – 2015
Background Patients with myalgic encephalomyelitis (ME, also called chronic fatigue
syndrome) may respond most favorably to frequent vitamin B12 injections, in vital
combination with oral folic acid. However, there is no established algorithm for …
Cardiovascular control in women with fibromyalgia syndrome: do casual methods provide non redundant information compared to more traditional approaches?
AR Zamunér, A Porta, CP Andrade, A Marchi, M Forti… – American Journal of …, 2015
Abstract The cardiovascular autonomic control and the baroreflex sensitivity (BRS) have
been widely studied in FMS patients through the computation of linear indices of
spontaneous heart period (HP) and systolic arterial pressure (SAP) variabilities. However, …
Aberrant Analgesic Response to Medial Branch Blocks in Patients With Characteristics of Fibromyalgia
CM Brummett, AG Lohse, A Tsodikov, SE Moser… – Regional Anesthesia and …, 2015
Abstract Background and Objectives: Facet interventions for spine pain have high failure
rates, and preprocedural prediction of response is nearly impossible. A potential explanation
may be aberrant central pain processing as that existing in conditions like fibromyalgia. To …
[HTML] Effects of Whole-Body Vibration Therapy in Patients with Fibromyalgia: A Systematic Literature Review
D Collado-Mateo, JC Adsuar, PR Olivares… – … -Based Complementary and …, 2015
Objective. To review the literature on the effects of whole-body vibration therapy in patients
with fibromyalgia. Design. Systematic literature review. Patients. Patients with fibromyalgia.
Methods. An electronic search of the literature in four medical databases was performed to …
Six Syndromes with Surprising Psychotherapy Solutions
T Rodriguez, V Stern – Scientific American Mind, 2015
… These links to content published by NPG are automatically generated. Cognitive behavioral
therapy for fibromyalgia. … Utility of cognitive behavioral therapy as a treatment for insomnia in
patients with fibromyalgia. Nature Clinical Practice Rheumatology (01 Apr 2006). …
Comorbid Conditions Do Not Differ in Children and Young Adults with Functional Disorders with or without Postural Tachycardia Syndrome
G Chelimsky, K Kovacic, M Nugent, A Mueller… – The Journal of Pediatrics, 2015
… All patients underwent formal autonomic testing, Beighton scores assessment for joint
hypermobility (0-9), and fibromyalgia tender points (0-18) (43 subjects). Results. … All subjects with
fibromyalgia by tender point-examination had a Beighton score ≥4 (P = .002). Conclusions. …
Mast cell infiltrates in vulvodynia represent secondary and idiopathic mast cell hyperplasias
S Regauer, B Eberz, C Beham‐Schmid – APMIS, 2015
… Similar to other chronic pain syndromes among which are chronic pelvic and bladder pain,
fibromyalgia, and atopic dermatitis morphological correlates are hyperinnervation and increased
infiltrates of mast cells [3-5]. Activated mast cells release pre-stored or rapidly produced …
Biological stress systems, adverse life events and the onset of chronic multisite musculoskeletal pain: a 6-year cohort study
E Generaal, N Vogelzangs, GJ Macfarlane, R Geenen… – Annals of the Rheumatic …, 2015
… Previous studies mostly defined chronic widespread pain, a cardinal symptom of the fibromyalgia
syndrome, as axial and bilateral pain above and below the waist.41 With this somewhat ‘less
stringent’ definition, we may have included some patients with milder pain. …
Speed, science and optimal pain relief
RA Moore – International Journal of Clinical Practice, 2015
… For example, a retrospective analysis of patients with chronic back pain or fibromyalgia revealed
that patients rated their treatment as successful if their pain was reduced by 50–70%, from a level
of 5–10 on a visual analogue scale (total score 10) to below three (no more than …
[PDF] An Insight of D 鄄 Ribose Metabolic Imbalance in Type 2 Diabetes Mellitus
T SU, RQ HE – Progress in Biochemistry and Biophysics, 2015
… 14-15]. Ribose is often marked as a supplement for bodybuilders with a common
recommended daily dose of 5g or more and has also been used to reduce fatigue
in fibromyalgia and chronic fatigue syndrome [2,16]. Ribose …
by admin | Apr 16, 2015 | Uncategorized
Ketamine, a long known anesthetic drug, has recently experienced resurgence in use due to the serendipitous discovery of new activities. These new activities have afforded new treatment options for notoriously difficult to treat diseases such as depression and chronic pain.
Ketamine has been called the pharmacologist’s nightmare due to it’s numerous mechanisms of action, making it difficult to pinpoint exactly what makes the drug so effective for specific diseases. A new study published in Biological Psychiatry found that ketamine induced large-scale persistent network reconfiguration in monkeys. The scientists believe that this activity may be critical for ketamine’s anti-depressive effects.
These findings could rapidly advance the development of a ketamine-based drug for the treatment of depression. Moreover, it opens the door for more physicians to use existing ketamine therapeutics off label to treat depression that is resistant to conventional antidepressants.
Dr. Hanna’s clinical team at the Florida Spine Institute has used intravenous ketamine therapy to treat many types of disorders, including depression. To learn more about intravenous ketamine infusions, click here. To find out if ketamine therapy is right for you, please make an appointment with Dr. Hanna.
For full article, visit: http://www.sciencedirect.com/science/article/pii/S0006322315001535
by admin | Jan 21, 2015 | Uncategorized
It’s been a hard day, and Joe’s back is killing him.
His wife has some Percocet left over from a trip to the dentist, and there’s that big bottle of Tylenol under the sink, so Joe grabs a couple of each and washes them down with a slug of beer.
Luckily for Joe, he’s a fictional character invented for this article. But there are a lot of real-life Joes out there making big mistakes with over-the-counter and prescription pain pills.
Can you spot Joe’s mistakes? Joe didn’t make every mistake in the book. But he made quite a few.
Here’s WebMD’s list of common pain pill mistakes, compiled with the help of pharmacist Kristen A. Binaso, RPh, spokeswoman for the American Pharmacists Association; and pain specialist Eric R. Haynes, MD, founder of Comprehensive Pain Management Partners in Trinity, Fla.
Pain Medications Mistake No.1:
If 1 Is Good, 2 Must Be Better
Doctors prescribe pain pills at the doses they believe will offer the greatest benefit at the least risk. Doubling or tripling that dose won’t speed relief. But it can easily speed the onset of harmful side effects.
“The first dose of a pain medication may not work in five minutes the way you want. But this does not mean you should take five more,” Binaso says. “With some pain drugs, if you take additional doses, it makes the first dose not work as well. And with others, you end up in the emergency room.”
If you’ve given your pain medication time to work, and it still does not control your pain, don’t double down. See your doctor about why you’re still hurting.
“This ‘one is good so two must be better’ thing is a common problem,” Haynes says. “Patients should follow the instructions their doctor gives. Ask before leaving the office: Can I take an extra pill if I still hurt? What is the upper limit for this medication?”
Another bad idea is trying to boost the effect of one kind of pain pill by taking another.
“There may be ibuprofen, acetaminophen, and naproxen in the house, and a person may take them all,” Binaso says.
This can escalate into a very bad situation, Haynes says.
Pain Medications Mistake No. 2:
Duplication Overdose
People often take over-the-counter pain drugs — and even prescription pain drugs — without reading the label. That means they often don’t know which drugs they’re taking. That’s never a good idea.
And if they take another over-the-counter drug — either for extra pain relief or for other reasons — they may be getting an overdose. That’s because many OTC drugs are combination pills that carry a full dose of pain pill ingredients.
In Joe’s case, he’s taken a prescription pain pill that contains acetaminophen along with a second full dose of acetaminophen from Tylenol, putting him at risk of injury.
Pain Medications Mistake No. 3:
Drinking While Taking Pain Drugs
Pain medications and alcohol generally enhance each other’s effect. That’s why many of these prescription medications carry a “no alcohol” sticker.
That sticker shows a martini glass covered by the international “No” sign of a circle with a slash. But it applies to wine and beer just as much as it does to spirits.
“A common misperception is people see that sticker and think, ‘I’m OK as long as I don’t drink liquor — I can have a beer.’ But no alcohol means no alcohol,” Binaso says.
“The patient should heed that alcohol warning, because it can be a major problem if they do not,” Haynes says. “Alcohol can make you inebriated, and some pain medications can make you have that feeling as well. You can easily get yourself into trouble.”
Drinking alcohol can be a problem even with over-the-counter pain drugs.
Pain Medications Mistake No. 4:
Drug Interactions
Before taking any pain pill, think about what other medicines, herbal remedies, and supplements you are taking. Some of these drugs and supplements may interact with pain medications or increase the risk of side effects.
For example, aspirin can affect the action of some non-insulin diabetes drugs; codeine and oxycodone can interfere with antidepressants.
You should give your doctor a complete list of all the drugs, herbs, and supplements you take — before getting any prescription.
If buying over-the-counter medications, Binaso recommends showing a list of everything else you’re taking to the pharmacist.
Pain Medications Mistake No. 5:
Drugged Driving
Pain medications can make you drowsy. Different people react differently to different drugs.
“How I react to a pain medication is different from how you react,” Binaso says. “It may not make me drowsy, but may make you drowsy. So I recommend trying it at home first, and see how you feel. Don’t take two pills and go out driving.”
Pain Medications Mistake No. 6:
Sharing Prescription Medicines
Unfortunately, it’s very common for people to share prescription medications with friends, relatives, and co-workers. Not smart, Haynes and Binaso say — particularly when it comes to pain medications.
“If a fairly healthy person is taking a medicine because she is in pain, and wants to give some pills to Uncle Joe because he is hurting — well, this is a potential problem,” Haynes says. “Uncle Joe may have a problem that keeps his body from eliminating the drug, or he may have an allergic reaction, or the drug may interact with a medication he is taking, with life-threatening results.”
Pain Medications Mistake No. 7:
Not Talking to the Pharmacist
It’s not easy to read drug labels, even if you can make out the small print. If you have a question about either a prescription or OTC drug, ask the pharmacist.
“That’s why I’m in the store,” Binaso says. “You may have to wait a couple of minutes for me to finish what I’m doing. But you’ll get the information you need to take the right medicine the right way. Just say, ‘Tell me about this medicine; what should I be on the lookout for?'”
Pain Medications Mistake No. 8:
Hoarding Dead Drugs
Joe’s wife is actually to blame for one of his mistakes. She should have disposed of those extra pain pills once she was over her dental pain.
Why? One reason is that pills stored at home start breaking down soon after their expiration date. That’s especially true of drugs kept in the moist environment of the bathroom medicine cabinet.
“People say, “That drug is only a year past its expiration date; isn’t it good?” But if you take a pill that’s broken down, it may not work — or you may end up in the emergency room because of reaction to a breakdown product. That is really common,” Binaso says.
Another reason that it’s dangerous to hoard is that the drugs may tempt someone else into making a very bad choice.
“Teen drug abuse is really up, especially with pain medications,” Binaso says. “It is not uncommon for kids to go to their parents’ or grandparents’ medicine cabinet and then go to a party and put the drugs in a bowl.”
Pain Medications Mistake No. 9:
Breaking Unbreakable Pills
Pills are actually little drug-delivery machines. They don’t work the way they’re supposed to when taken apart the wrong way.
Scored pills should be cut only across the line, Binaso says. Those without scoring should not be cut at all, unless you’re specifically instructed to do so.
“When you start chopping up pills like that, the pill may not work,” she says. “We find more and more people are doing this. And then they say, “Oh, that pill had a really bad taste. That is because they cut away the coating.”
Source: Web MD
By Daniel J. DeNoon
Reviewed By David T. Derrer, MD