by admin | Sep 23, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
[HTML] Upper urinary tract damage caused by ketamine snorting—A report of nine cases
HY Lee, YC Hsu, CY Hsu, ECL Chou, CC Li, YS Juan… – Urological Science, 2015
Objective The toxicity of ketamine to genitourinary system not only involved in lower urinary
tract, which include urinary frequency, urgency, suprapubic pain, dysuria and hematuria, but
also upper urinary tracts. However, the reports of ketmaine-induced upper urinary tract …
Inconsistency of allometric scaling for dissociative anesthesia of wild felids
AB Carregaro, GC Freitas, SP Bisetto, NV Xavier… – Veterinary anaesthesia and …, 2015
… Keywords: allometric scaling; dissociative anesthesia; ketamine; metabolic rate; xylazine.
Abstract. … Objective. To evaluate allometric scaling for ketamine–xylazine (KX) anesthesia
in wild felids using domestic cats for reference. Study design. …
[PDF] The ERα-PI3K Cascade in Pro-opiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice
L Zhu, P Xu, X Cao, Y Yang, AO Hinton Jr, Y Xia… – Endocrinology, 2015
… Hypothalamic ER -p85 interaction and phosphorylation of AKT in response to icv PPT
Female C57Bl6 mice (12 weeks) were anesthetized with ip injections of
ketamine/xylazine cocktail (100 mg/kg ketamine and 10 mg/kg xylazine). …
[HTML] Effects of leptin on sympathetic nerve activity in conscious mice
DA Morgan, F Despas, K Rahmouni – Physiological Reports, 2015
… Here, we examined the sympathetic responses evoked by leptin in conscious mice. Mice
were instrumented, under ketamine/xylazine anesthesia, with renal or lumbar SNA
recordings using a thin (40 gauge) bipolar platinum–iridium wire. …
[PDF] Treatment of Pain with Antidepressants
B Kerr, C Benson, K Mifflin, SJB Jesudasan, S Dursun… – Klinik Psikofarmakoloji …, 2015
… depression43-45. There has been a great deal of interest in the NMDA receptor antagonist
ketamine and its rapid acting antidepressant action when infused46,47, and it is interesting that
this drug has also been used in treatment of therapy-resistant chronic pain48. …
Use of LigaSure on bile duct in rats. An experimental study.
A Marte, L Pintozzi – Minerva pediatrica, 2015
… in rats. MATERIALS AND METHODS: Thirty Wistar rats weighing 70 to 120gr were
employed for this study. The animals were all anaesthetized with intraperitoneal
Ketamine and then divided into three groups. The first group …
[HTML] Maxcal-C (a polyherbal formulation) prevents ovariectomy-induced osteoporosis in rats
RA Maheshwari, F Dhakwala, R Balaraman, AK Seth… – Indian Journal of …, 2015
… Standard drug Calcium Sandoz (cholecalciferol), ketamine hydrochloride, diazepam, povidone,
and ampicillin were purchased from commercial market. … The rats were anesthetized with injection
of ketamine hydrochloride (40 mg/kg. ip) and diazepam (5 mg/kg, im). …
Positive reinforcing effect of oxytocin microinjection in the rat central nucleus of amygdala
K László, A Kovács, O Zagoracz, T Ollmann, L Péczely… – Behavioural Brain Research, 2015
… 00 h. 2.2. Surgery. Rats were anesthetized ip by ketamine supplemented with
diazepam (Calypsol and Seduxen, Richter Gedeon, Hungary, ketamine: 80
mg/kg body weight, diazepam: 20 mg/kg body weight). Animals were …
Minocycline Attenuates Depressive‐like Behaviour Induced by Rat Model of Testicular Torsion: Involvement of Nitric Oxide Pathway
SSS Saravi, SE Mousavi, SSS Saravi, AR Dehpour – Basic & Clinical Pharmacology & …, 2015
… Testicular Torsion/Detorsion Animals were anaesthetized with intraperitoneal injection of ketamine
HCl (50 mg/kg) and chlorpromazine (25 mg/kg). … 30 days. Testosterone assay At day 30, the rats
were anaesthetized with intraperitoneal injection of ketamine HCl (50 mg/kg) …
Spinal Reflexes and Windup In Vitro: Effects of Analgesics and Anesthetics
I Rivera‐Arconada, C Roza, JA Lopez‐Garcia – CNS Neuroscience & Therapeutics, 2015
… Spinal cord mechanisms may contribute toward analgesia and akinesia. Ketamine.
The general anesthetic ketamine is a noncompetitive blocker of NMDA receptors
that also shows activity on several ionic channels. As expected …
Augmentation Therapy With Serial Intravenous Ketamine Over 18 Months in a Patient With Treatment Resistant Depression.
S Hassamal, M Spivey, AK Pandurangi – Clinical Neuropharmacology, 2015
Abstract Major depressive disorder is a severe illness that affects 3% to 7% of adults
annually in the United States. About 30% of these individuals are refractory to multiple
treatment trials. Recent reports have found a significant and almost immediate …
Ketamine Increases Permeability and Alters Epithelial Phenotype of Renal Distal Tubular Cells Via a GSK‐3β‐Dependent Mechanism
HY Shyu, CJ Ko, YC Luo, HY Lin, SR Wu, SW Lan… – Journal of Cellular …, 2015
Abstract Ketamine, a dissociative anesthetic, is misused and abused worldwide as an illegal
recreational drug. In addition to its neuropathic toxicity, ketamine abuse has numerous
effects, including renal failure; however, the underlying mechanism is poorly understood. …
More effective induction of anesthesia using midazolam-butorphanol-ketamine-sevoflurane compared with ketamine-sevoflurane in the common marmoset monkey ( …
H ISHIBASHI – Journal of Veterinary Medical Science, 2015
The common marmoset has been increasingly used for research in the biomedical field;
however, there is little information available regarding effective methods of anesthesia in this
species. This study retrospectively analyzed 2 regimens of anesthesia induction: …
[HTML] Comparison of Ketamine–Medetomidine-butorphanol and Ketamine–dexmedetomidine-butorphanol Anesthesia in Rats
R Costea, D Lastofka, M Mehedinţu – Agriculture and Agricultural Science Procedia, 2015
Abstract We evaluated the effect of ketamine-dexmedetomidine-butorphanol (K, 80 mg/kg;
D, 0.25 mg/kg, B, 0.5 mg/kg) and ketamine-medetomidine-butorphanol (K, 80 mg/kg; M, 0.25
mg/kg, B, 0.5 mg/kg) administered intraperitoneally, during anesthesia and immediate …
Pulmonary immunostimulation with MALP-2 in influenza virus-infected mice increased survival after pneumococcal superinfection
K Reppe, P Radünzel, K Dietert, T Tschernig, T Wolff… – Infection and Immunity, 2015
… Five days after IAV infection, 114 the mice were anesthetized intraperitoneally
(ip) with ketamine (80 mg/kg, Ketavet®, Pfizer, 115 … re-suspended in sterile PBS.
Mice were anesthetized ip with ketamine and xylazine and 123 …
Atorvastatin along with imipenem attenuates acute lung injury in sepsis through decrease in inflammatory mediators and bacterial load
S Choudhury, K Kannan, BS Maruti, MP Addison… – European Journal of …, 2015
… ad libitum. The animals were anesthetized by injection of xylazine (10 µg/g body
weight, intraperitoneally) and ketamine (80 µg/g body weight, intraperitoneally) and
a 2-cm ventral midline incision was performed. The cecum …
[HTML] Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase
YJ Lai, GJ Chang, YH Yeh, JHS Pang, CC Huang… – PLOS ONE, 2015
… All the surgery was performed under ketamine and xylazine ip anesthesia, and all efforts were
made to minimize suffering. Housing and maintenance was provided by Chang Gung University,
All animals were fed a standard chow diet with free access to water. …
[HTML] Serotonin 5-HT 7 receptor agonist, LP-211, exacerbates Na+, K+-ATPase/Mg 2+-ATPase imbalances in spinal cord-injured male rats
A Norouzi-Javidan, J Javanbakht, F Barati, N Fakhraei… – Diagnostic Pathology, 2015
… Animals were anesthetized by intraperitoneal injection of a mixture of ketamine hydrochloride
(75 mg/kg) and xylazine hydrochloride (5 mg/kg). … All animals were anesthetized (ketamine
hydrochloride 10 % + xylazine 2 %, in 80 and 5 mg/kg doses, respectively). …
[HTML] Interleukin-17A and Neutrophils in a Murine Model of Bird-Related Hypersensitivity Pneumonitis
M Ishizuka, Y Miyazaki, M Masuo, K Suhara, T Tateishi… – PLOS ONE, 2015
… They were then placed under light anesthesia with 100 mg/kg ketamine and 10 mg/kg xylazine,
and 5 μg of PDE in 25 μl of 0.9% saline was sprayed into each mouse’s trachea using an
intratracheal MycroSprayer® aerosolizer (Penn-century, Wyndmoor, PA, USA). …
Pertussis toxin reduces calcium influx to protect ischemic stroke in a middle cerebral artery occlusion model
Z Tang, S Li, P Han, J Yin, Y Gan, Q Liu, J Wang… – Journal of Neurochemistry, 2015
… blinded to the randomization. Permanent Middle Cerebral Artery Occlusion (pMCAO) Mice were
under Ketamine/Xylazine anesthesia (80 mg/kg Ketamine and 10mg/kg Xylazine, injected ip).
Standard aseptic surgical procedures were used throughout the procedure. The …
Radiofrequency Ablation (RFA)
Effectiveness and safety of computed tomography-guided radiofrequency ablation of renal cancer: a 14-year single institution experience in 203 patients
JD Iannuccilli, DE Dupuy, MD Beland, JT Machan… – European Radiology, 2015
Objectives To define effectiveness and safety of CT-guided radiofrequency ablation (RFA) of
renal tumours and prognostic indicators for treatment success. Methods Patients with a
single treatment of a solitary, biopsy-proven renal tumour with intent to cure over a 14-year …
Outcomes associated with ablation compared to combined ablation and transilluminated powered phlebectomy in the treatment of venous varicosities.
AT Obi, BN Reames, TJ Rook, SO Mouch, A Zarinsefat… – Phlebology/Venous Forum …, 2015
… RESULT: Venous clinical severity scores improved more with radiofrequency ablation +
transilluminated powered phlebectomy as compared to radiofrequency ablation alone
(3.8 ± 3.4 vs. 3.2 ± 3.1, p = 0.018). … radiofrequency ablation alone. …
Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations
S Mercadante, P Klepstad, G Paula Kurita, P Sjøgren… – Acta Oncologica, 2015
… Radiofrequency ablation (RFA). … RFA resulted more effective than radiotherapy and surgical
stabilization [99. Di Francesco A, Flamini S, Zugaro L, Zoccali C. Preoperative
radiofrequency ablation in painful osteolytic long bone metastases. …
[HTML] Efficiency and safety of radiofrequency-assisted hepatectomy for hepatocellular carcinoma with cirrhosis: A single-center retrospective cohort study
F Zhang, J Yan, XB Feng, F Xia, XW Li, KS Ma, P Bie – World J Gastroenterol, 2015
… These procedures include liver transplantation, resection, and radiofrequency ablation[ 5 ]. Liver
transplantation may be the best treatment option for cirrhotic patients with HCC because it involves
the simultaneous removal of both the cirrhotic liver and HCC[ 6 ]. However, the …
Ethanol ablation in post-biopsy liver hemorrhage following two failed Embolizations
MC Pope, DH Ballard, AL Sticker, C Ahuja… – Clinical Imaging, 2015
… C. The feeding vessels were identified and ablated with an additional 10 mL ethanol injection. …
to ultrasound-guided percutaneous ethanol injection for achieving hemostasis include techniques
such as cryoablation, radiofrequency (RF)-ablation, and cyanoacrylate glue …
[PDF] Catheter Ablation of Fascicular Ventricular Tachycardia: Long Term Clinical Outcomes and Mechanisms of Recurrence
Y Liu, Z Fang, B Yang, P Kojodjojo, H Chen, W Ju… – Circulation: Arrhythmia and …, 2015
… ablated. … Arrhythmia recurrences after an initially successful ablation were caused by recurrent
FVT involving the … Key words: ventricular tachycardia, radiofrequency, idiopathic left ventricular
tachycardia, fascicular ventricular tachycardia, outcomes, radiofrequency ablation …
Liver metastases from adenocarcinomas of unknown primary site: management and prognosis in 68 consecutive patients
E Algin, A Ozet, O Gumusay, G Yilmaz, S Buyukberber… – Wiener klinische …, 2015
… shown in Fig. 1. Among 39 patients who were managed with chemo- therapy, 12
patients received additional locoregional therapies including radiofrequency ablation
or transar- terial chemoembolization. Median OS was 9.4 …
[HTML] The Prognostic Value of Platelet Count in Patients With Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Q Pang, K Qu, JY Zhang, SD Song, SS Liu, MH Tai… – Medicine, 2015
… Abbreviations: HBV = hepatitis B virus, HCC = hepatocellular carcinoma, HCV = hepatitis C virus,
HR = hazard ratio, MPV = mean platelet volume, OS = overall survival, PLT = platelet count, RFA =
radiofrequency ablation, RFS = recurrence-free survival, TACE = transcatheter …
Safety and Feasibility of Open Chest Epicardial Mapping and Ablation of Ventricular Tachycardia During the Period of Left Ventricular Assist Device Implantation
M Patel, F Rojas, FR Shabari, L Simpson, W Cohn… – Journal of Cardiovascular …, 2015
… Endocardial and epicardial radiofrequency ablation of ventricular tachycardia associated with
dilated cardiomyopathy: The importance of low-voltage scars. … Comparison of epicardial
cryoablation and irrigated radiofrequency ablation in a swine infarct model. …
Contact Force Variability during Catheter Ablation of Atrial Fibrillation: The Role of Atrial Rhythm and Ventricular Contractions: Co-Force AF Study
A Sarkozy, D Shah, J Saenen, J Sieira, T Phlips… – Circulation: Arrhythmia and …, 2015
… 3 Background Lesion formation by using radiofrequency (RF) current depends on the power
delivered, duration of energy application, temperature, tip size, and tip orientation. … given RF power1.
Irrigated tip ablation catheters capable of real-time CF measurement have …
[HTML] Pulmonary vein isolation using the visually guided laser balloon: a prospective, multicenter, and randomized comparison to standard radiofrequency ablation
SR Dukkipati, F Cuoco, I Kutinsky, A Aryana… – Journal of the American …, 2015
Background Balloon catheters have been designed to facilitate pulmonary vein (PV)
isolation in patients with paroxysmal atrial fibrillation (AF). The visually guided laser balloon
(VGLB) employs laser energy to ablate tissue under direct visual guidance. Objectives …
Optimal Temperature for Radiofrequency Ablation of Lumbar Medial Branches for Treatment of Facet‐Mediated Back Pain
S Costandi, M Garcia‐Jacques, T Dews, M Kot, K Wong… – Pain Practice, 2015
Background Radiofrequency ablation (RFA) of the medial branch nerves that innervate the
facet joints is a well-established treatment modality; however, studies to determine the
optimal radiofrequency ablation temperature are lacking. A wide range (70 to 90 C) has …
[HTML] Catheter Ablation of Atrial Fibrillation: Advent of Second-Generation Technologies
E Buch, K Shivkumar – Journal of the American College of Cardiology, 2015
… and wide-area isolation (5), with or without additional lesion sets targeting non-PV
foci (6) or modifying atrial substrate. All of these techniques initially used
point-by-point ablation with radiofrequency (RF) ablation catheters. …
[HTML] Computed tomography-guided percutaneous trephine removal of the nidus in osteoid osteoma patients: experience of a single center in Brazil
M Petrilli, AA Senerchia, AS Petrilli, HM Lederman… – Radiologia Brasileira, 2015
… Osteoid osteoma: CTguided percutaneous radiofrequency ablation and follow-up in 47 patients.
J Vasc Interv Radiol. 2001;12:717–722. … Peyser A, Applbaum Y, Khoury A, et al. Osteoid osteoma:
CT-guided radiofrequency ablation using a water-cooled probe. Ann Surg Oncol. …
Proton beam therapy for metastatic liver tumors
N Fukumitsu, T Okumura, D Takizawa, H Makishima… – Radiotherapy and Oncology, 2015
… The maximal diameter of the lesions was 1–18 cm (median, 4 cm). Of the 140 patients, 87
had received another form of treatment before PBT, such as chemotherapy, radiofrequency
ablation, transcatheter arterial chemoembolization, and surgery. …
Accuracy of Late Gadolinium Enhancement-Magnetic Resonance Imaging in the Measurement of Left Atrial Substrate Remodeling in Patients With Rheumatic Mitral …
D Zhu, Z Wu, RJ van der Geest, Y Luo, J Sun, J Jiang… – International Heart Journal, 2015
… We enrolled adult patients with rheumatic mitral valve disease and persistent AF who un-
derwent open-heart surgery for mitral valve replacement with concurrent radiofrequency
ablation for AF at our institution between February 2013 and March 2014. …
Predictive value of nodule size and differentiation in HCC recurrence after liver transplantation
GG Piero, P Domenico, F Di Benedetto, M Elena… – Surgical Oncology, 2015
… Generally, radiofrequency ablation (RFA) was proposed in cases of a single tumor less than 3
cm, whereas a single tumor > 3 cm or multifocal lesions in patients with impaired liver function
were directed instead to treatment with trans-arterial chemoembolization (TACE). …
Radiofrequency ablation or stripping of large-diameter incompetent great saphenous varicose veins with C2 or C3 disease
EV Shaidakov, AG Grigoryan, EA Ilyukhin, VL Bulatov… – Journal of Vascular Surgery: …, 2015
Objective The objectives of this study were to compare the results of radiofrequency ablation
(RFA) and stripping for large-diameter varicose target veins for the period of 1 year, based
on a composite end point; to analyze the pain severity on a digital rating scale for 7 days …
Clinical outcomes and risk factors of hepatocellular carcinoma treated by liver transplantation: A multi-centre comparison of living donor and deceased donor …
Z Hu, Z Qian, J Wu, J Zhou, M Zhang, L Zhou, S Zheng – Clinics and Research in …, 2015
… HCC: hepatocellular carcinoma; LDLT: living donor liver transplantation; DDLT: deceased donor
liver transplantation; GWRW: graft weight/recipient weight; TACE: transcatheter arterial
chemoembolisation; RFA: radiofrequency ablation; PEI: percutaneous ethanol injection; ICU …
[PDF] Hepatocellular carcinoma treatment strategies–a case-based review
R Alves, MT Gomes, CS Macedo, HP Miranda, F Nery – Journal of Solid Tumors, 2015
… Resection techniques have been refined, from the use of new radiofrequency ablation resection
devices to laparoscopic approaches, both showing to diminished blood loss [1, 2]. A recent
meta-analysis showed that laparoscopic approach decreases blood loss, transfusion …
Complex Regional Pain Syndrome (CRPS/RSD)
Skin sympathetic function in complex regional pain syndrome type 1
A Poudel, M Asahina, Y Fujinuma, Y Yamanaka… – Clinical Autonomic …, 2015
… 10.1007/s10286-015-0314-x. Copyright information. Abstract. Purpose. Cutaneous
sympathetic pathophysiology in complex regional pain syndrome type 1 (CRPS-1) is
not yet completely understood. To evaluate cutaneous sympathetic …
Substance P spinal signaling induces glial activation and nociceptive sensitization after fracture
WW Li, TZ Guo, X Shi, Y Sun, T Wei, DJ Clark… – Neuroscience, 2015
… hypersensitivity. Abstract. Tibia fracture in rodents induces substance P
(SP)-dependent keratinocyte activation and inflammatory changes in the hindlimb,
similar to those seen in complex regional pain syndrome (CRPS). In …
Economic impact of mgnregp on rural livelihood security in tumkur district, karnataka–a sam analysis
CHR Gowda – 2015
… Item Type: Thesis (Masters). Divisions: RP-Market Institutions and Policies. CRPS: CGIAR
Research Program on Policies, Institutions, and Markets. Uncontrolled Keywords: Economic
Impact, MGNREGP, Rural Livelihood Security, Karnataka, SAM analysis. …
[PDF] DMSA-coated Iron Oxide Nanoparticle Greatly Affect the Expression of Genes Coding Cysteine-rich Proteins by its DMSA Coating
L Zhang, X Wang, J Zou, Y Liu, J Wang – Chemical Research in Toxicology, 2015
… times. The results revealed that about one fourth of DEGs coded cysteine-rich proteins
(CRPs) in all cells under each treatment, indicating that the nanoparticles greatly
affected the expressions of CRP-coding genes. Additionally …
Changing appearance using visual illusions improves ownership of the painful hand in complex regional pain syndrome
J Lewis, C McCabe, R Newport – 2015
… Abstract. Background and aims People with Complex Regional Pain Syndrome (CRPS)
experience a diminished sense of ownership of their painful limb. … Thirty nine patients with CRPS
of one arm were randomly allocated to either a control or experimental group. …
The role of genetically‐engineered pigs in xenotransplantation research
DKC Cooper, B Ekser, J Ramsoondar, C Phelps… – The Journal of Pathology, 2015
… This is because of the expression of human complement-regulatory proteins (CRPs) on the
surface of vascular endothelial cells. Pigs have similar CRPs, but these are relatively inefficient
at protecting the pig cells from human complement-mediated injury [13]. …
Individuality: How knowledge of body perception disturbance can inform treatment
J Lewis – 2015
… Lewis, J. (2015) Individuality: How knowledge of body perception disturbance can inform
treatment. In: International Association of the Study of Pain (IASP) CRPS SIG, Zurich, Switzerland,
31 August – 1 September 2015. [img] Preview. PDF 1MB. Abstract. …
Spinal Cord Stimulation (SCS) and Functional Magnetic Resonance Imaging (fMRI): Modulation of Cortical Connectivity With Therapeutic SCS
M Deogaonkar, M Sharma, C Oluigbo, DM Nielson… – … : Technology at the Neural …, 2015
… Methods. Ten patients with complex regional pain syndrome (CRPS) or neuropathic leg pain
underwent thoracic epidural spinal cord stimulator implantation. Stimulation parameters associated
with “optimal” pain reduction were evaluated prior to imaging studies. …
[PDF] Similarity-based semi-local estimation of EMOS models
S Lerch, S Baran – arXiv preprint arXiv:1509.03521, 2015
… The most popular scoring rules providing summary measures of predictive performance are the
logarithmic score, ie, the negative logarithm of the predictive PDF evaluated at the verifying
observation, and the continuous ranked probability score (CRPS; Gneiting and Raftery …
Review of Plastic Surgery
DW Buck II – 2015
[PDF] Independent CRP-Commissioned External Evaluation of the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH)
J Compton, D McLean, B Emmens, M Balagamwala – 2015
… development partners (IFPRI, 2011). CRPs are not legal entities and therefore legal
and financial responsibility for A4NH ultimately rests with the lead CGIAR Center
and its Board of Trustees (IFPRI- BOT). 2. IFPRI is legally …
[PDF] Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis
C Compagnone, F Tagliaferri – Acta Bio Medica Atenei Parmensis, 2015
… Different diseases could lead to neuro- pathic pain including postsurgical pain, post-herpetic
neuralgia (PHN), spinal cord stenosis (SCS), Complex Regional Pain Syndrome (CRPS), Diabetic
peripheral neuropathy (DPN), and chemotherapy induced pe- ripheral neuropathy. …
Traumatic Life Events and Psychopathology in a High Risk, Ethnically Diverse Sample of Young Children: A Person-Centered Approach
MJ Hagan, MJ Sulik, AF Lieberman – Journal of abnormal child psychology, 2015
… Conditional response probabilities (CRPs) are defined as the probability that an
individual from a specific latent class will endorse an item. CRPs provide … across
classes. CRPs for the exploratory LCA model are shown in Fig. …
Two placebo-controlled, randomized withdrawal studies to evaluate the fentanyl 1-day patch in opioid-naïve patients with chronic pain
T Arai, Y Kashimoto, Y Ukyo, Y Tominaga, K Imanaka – Current Medical Research …, 2015
… study]) and the other study included opioid-naïve subjects with neuropathic pain (post- herpetic
neuralgia, complex regional pain syndrome [CRPS], or chronic postoperative pain; … included: had
osteoarthritis, low back pain, post-herpetic neuralgia, CRPS, or chronic …
[PDF] Challenges of Peripheral Nerve Stimulator Implantation in a Patient with New Onset Thrombocytopenia
S Thompson
… We present a patient with complex regional pain syndrome (CRPS)-like symptoms of the lateral
femoral cutaneous nerve after laparoscopic hysterectomy who underwent successful
ultrasound-guided PNS trial using SCS leads and unfortunate delayed implantation due to …
Improving student learning via mobile phone video content: Evidence from the BridgeIT India project
M Wennersten, ZB Quraishy, M Velamuri – International Review of Education
[PDF] The Association Between Soft Tissue Releases and Bony Resections Performed During Total Knee Arthroplasty and Patients’ Pain and Satisfaction Postoperatively
M Carter – 2015
Page 1. Western University Scholarship@Western Electronic Thesis and Dissertation Repository
September 2015 The Association Between Soft Tissue Releases and Bony Resections Performed
During Total Knee Arthroplasty and Patients’ Pain and Satisfaction …
[PDF] Parthasarathy Rao and Cynthia Bantilan. 2015. Grain Legumes Production, Consumption and Trade Trends in Developing Countries
S Nedumaran, P Abinaya, P Jyosthnaa, B Shraavya
… Markets (PIM). Financial support by CRPs Grain Legumes and Policies, Institutions
and Markets are gratefully acknowledged. This working paper has gone through
the standard peer-review procedure of ICRISAT. The authors …
NEUROMODULATORY DEVICES, SYSTEMS, AND METHODS FOR TREATING FIBROMYALGIA
AR Rezai, M Deogaonkar – US Patent 20,150,251,008, 2015
… In subjects with fibromyalgia as well as other conditions (eg, hot flashes, CRPS, etc.),
clinicians have used pharmacological blockade of the sympathetic nervous system, and
in particular the stellate ganglion, to achieve some clinical benefit. …
Fibromyalgia
Psychiatric Disorders in Young Adults Diagnosed with Juvenile Fibromyalgia in Adolescence.
NR Cunningham, ST Tran, AM Lynch-Jordan, TV Ting… – The Journal of …, 2015
OBJECTIVE: Adolescents with juvenile-onset fibromyalgia (JFM) have increased rates of
psychiatric disorders, but to our knowledge no studies have examined psychiatric disorders
in adolescents with JFM when they enter young adulthood. This study examined the …
Fibromyalgia beyond reductionism. Heart rhythm fractal analysis to assess autonomic nervous system resilience
C Lerma, LA Martinez-Martinez, N Ruiz, A Vargas… – Scandinavian Journal of …, 2015
Objectives: The prevailing linear reductionist medical model seems unable to explain
complex multisymptomatic illnesses such as fibromyalgia (FM) and similar maladies.
Paradigms derived from the complexity theory may provide a coherent framework for …
Exploring the role of peripheral mechanisms: An evaluation of a theory-based approach to reducing symptoms of fibromyalgia
K Mooney – 2015
Abstract: This mixed method study presented an integrative approach for the treatment of
fibromyalgia, the rationale that justifies the approach, and an evaluation of two integrated
components of this protocol designed to mitigate symptoms of fibromyalgia. Considering …
Chronic Widespread Back Pain is Distinct from Chronic Local Back Pain: Evidence from Quantitative Sensory Testing, Pain Drawings, and Psychometrics.
A Gerhardt, W Eich, S Janke, S Leisner, RD Treede… – The Clinical journal of pain, 2015
… Therefore, this study compared quantitative-sensory-testing (QST) profiles of
non-specific chronic back pain patients with CLP (n=48) and CWP (n=29) with
pain-free controls (PCs, n=40) and Fibromyalgia patients (FMS, n=90). …
Meta-analytic evidence for decreased heart rate variability in chronic pain implicating parasympathetic nervous system dysregulation.
LM Tracy, L Ioannou, KS Baker, SJ Gibson… – PAIN, 2015
… frequency HRV in chronic pain, implicating a decrease in parasympathetic activation.
These effects were heavily influenced by fibromyalgia studies. Future research would
benefit from wider use of standardised definitions of …
[HTML] Analgesic effect of cathodal transcranial current stimulation over right dorsolateral prefrontal cortex in subjects with muscular temporomandibular disorders: study …
RA Brandão Filho, AF Baptista, RAFS Brandão… – Trials, 2015
… In a fibromyalgia study using transcranial magnetic stimulation (TMS), the authors found higher
thresholds in both sides of the resting motor cortex with lower up regulation responses.
Furthermore, they found lower intracortical facilitation and inhibition. …
Clinical Research Methodology 1: Study Designs and Methodologic Sources of Error
DI Sessler, PB Imrey – Anesthesia & Analgesia, 2015
… The distinction can be nonobvious. For example, consider a study in which investigators compared
anesthetic requirement in patients with and without fibromyalgia. … But, in fact, fibromyalgia is the
exposure in this study and anesthetic requirement is the outcome. …
[HTML] Economic evaluation in chronic pain: a systematic review and de novo flexible economic model
W Sullivan, M Hirst, S Beard, D Gladwell, F Fagnani… – The European Journal of …, 2015
… While the attributes and management of specific diseases associated with chronic pain, such
as fibromyalgia and osteoarthritis, and different analgesic requirements for neuropathic versus
other chronic pain may have justifiably led to modelling heterogeneity, clinical …
[PDF] Evaluation of the Immediate Effect of Auricular Acupuncture on Pain and Electromyographic Activity of the Upper Trapezius Muscle in Patients with Nonspecific Neck …
ACO Silva, DA Biasotto-Gonzalez, DM Santos… – … -Based Complementary and …, 2015
… NS-NP could contribute to the following: (i) a standardization of the points to be used as stimuli
for the treatment of abnormalities caused in this muscle by mechanical injuries, myofacial tension
(with or without trigger-points), and systemic diseases such as fibromyalgia; (ii) an …
Ehlers Danlos syndrome and gastrointestinal manifestations: a 20‐year experience at Mayo Clinic
AD Nelson, MA Mouchli, N Valentin, D Deyle… – Neurogastroenterology & …, 2015
… hernia,[7] rectal evacuation disorder,[8] diverticulosis, gastritis,[9] constipation, diarrhea, nausea,
vomiting, abdominal pain, and reflux disease.[10] Several non-musculoskeletal symptoms often
found in patients with functional GI disorders such as fibromyalgia, fatigue, cognitive …
[HTML] Real-life assessment of the validity of patient global impression of change in fibromyalgia
E Rampakakis, PA Ste-Marie, JS Sampalis, A Karellis… – RMD Open, 2015
Objectives Patient Global Rating of Change (GRC) scales are commonly used in routine
clinical care given their ease of use, availability and short completion time. This analysis
aimed at assessing the validity of Patient Global Impression of Change (PGIC), a GRC …
[HTML] Increased Risk of Coronary Heart Disease in Patients with Primary Fibromyalgia and Those with Concomitant Comorbidity—A Taiwanese Population-Based Cohort …
CH Su, JH Chen, JL Lan, YC Wang, CH Tseng, CY Hsu… – PLOS ONE, 2015
Objectives Fibromyalgia has seldom been associated with coronary heart disease (CHD).
The aim of this study was to evaluate the risk of CHD in patients with fibromyalgia. Methods
We used a dataset of one million participants, systemically scrambled from the Taiwanese …
[HTML] Group cognitive-behavioral therapy for chronic pain adults: review of Brazilian trials
LF Kirchner, CC Jorge, MJD Reis – Revista Dor, 2015
… 26 . With regard to studied population, table 1 shows predominance of females in all studies,
being fibromyalgia (FM) the most frequent diagnosis. Nevertheless, literature … assertiveness,
3. (6 to 8), Fibromyalgia (100%), VAS. LSSI. RAS. Lorençatto …
[HTML] Chronic Pain Pharmacological Treatment in Patients with Depressive Disorders
C Aurilio, MC Pace, MB Passavanti, V Pota, P Sansone… – Journal of Psychiatry, 2015
… Patients with fibromyalgia present a reduced dopamine presynaptic activity in great many
brain regions, included hippocampus. Neurocircuits and neurochemistry. … [50] published
a review on amitriptyline for neuropathic pain and fibromyalgia. …
Medical Marijuana Patient Counseling Points for Healthcare Professionals Based on Trends in the Medical Uses, Efficacy, and Adverse Effects of Cannabis-Based …
JR Parmar, BD Forrest, RA Freeman – Research in Social and Administrative …, 2015
… All three medications have similarly been used in improving sleep, fibromyalgia, rheumatoid
arthritis associated pain, and spasticity in MS. A complete list of medical uses and included
publications can be reviewed in Table 5. Table 5. … Fibromyalgia, 1 16, 16, …
Identification and description of controlled clinical trials published in Physiotherapy journals in Spain
M Turrillas, M Sitjà‐Rabert, H Pardo… – Journal of Evaluation in …, 2015
… 16.7% of the identified studies were multicentric. Traumatology and orthopaedics was the most
studied field (33.3%) followed by neurology (15.4%). The most researched health problems were
back pain (17.24%) fibromyalgia, arthrosis and stroke (6.8% each). …
[HTML] Serum calprotectin (S100A8/9): an independent predictor of ultrasound synovitis in patients with rheumatoid arthritis
J Hurnakova, J Zavada, P Hanova, H Hulejova, M Klein… – Arthritis Research & …, 2015
… which is obtained by using several composite indexes [4–7]. Nevertheless, a clinical examination
might lack sensitivity in patients with mild synovitis, be limited in patients with established
deformities, and be overestimated in patients with concomitant fibromyalgia or other …
[HTML] Systematic review of the measurement properties of self-report physical activity questionnaires in healthy adult populations
Z Silsbury, R Goldsmith, A Rushton – BMJ Open, 2015
… 6 The review found strong evidence for effectiveness within cardiovascular disease, type 2
diabetes and obesity; and strong evidence for improved symptom management and quality of
life for patients with cancer, osteoarthritis, osteoporosis, fibromyalgia and depression. …
[PDF] Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis
C Compagnone, F Tagliaferri – Acta Bio Medica Atenei Parmensis, 2015
… JOP 2003; 4 (1): 1-10. 4. Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Ami- triptyline for
neuropathic pain and fibromyalgia in adults. … Review. 5. Moore RA, Wiffen PJ, Derry S, Toelle
T, Rice AS. Gabapen- tin for chronic neuropathic pain and fibromyalgia in adults. …
Illness deception
SB Nimmo – Occupational Medicine, 2015
… In a survey of US neuropsychologists, prevalence of malingering and symptom exaggeration
was found to be minor head injury 39%, fibromyalgia/chronic fatigue syndrome 35%, chronic
pain 31%, personal injury cases 29%, disability or workers compensation 30% and …
by admin | Aug 3, 2015 | Uncategorized
It has been estimated that 1 in 4 people in the US suffer from some form of chronic pain in their lifetime. The duration of this pain differs from person to person, spanning several weeks to many years.
Many sufferers of long-term chronic pain can have their daily wellbeing severely affected if treatments fail to offer appropriate levels of pain relief.
Of the more than 1.5 billion people worldwide said to suffer from chronic pain, the most common area affected is the lower back. The frequency of this is 23-26% of the global population.
Not surprisingly, this has been a hot area of research, which has produced treatment options from opioids to surgery. Opioids, while very effective for analgesia, can produce unwanted long term problems like dependence for chronic pain patients.
For this reason, surgical options are frequently presented for long term chonic pain patients. One such technique is spinal cord stimulation therapy (SCS), where pulses are delivered to the spinal cord by a small device implanted under the skin, emitting a form of paresthesia. As many as 50,000 patients in the US undergo SCS ever year to combat chronic pain.
Paresthesia is a sensation akin to tingling and is a result of SCS. When a device is turned on, an electrical current interrupts the pain signal being sent to the brain. Although a patient’s pain is not cured, SCS hopes to offer some temporarily relief.
Although SCS has been shown to reduce pain, many patients find the paresthesia that accompanies this to be uncomfortable.
This was to be the catalyst for scientists to develop a new form of SCS, one which still alleviates pain but reduces the effects of paresthesia in patients.
Traditional SCS uses frequencies of 40-60 hertz. Scientists decided to intensify this and use high-frequency pulses capable of delivering up to 10,000 hertzes. The new treatment has been named HF10.
Prof. Leonardo Kapural, lead study author and professor of anesthesiology at Wake Forest University School of Medicine and clinical director at Carolinas Pain Institute at Brookstown in Winston-Salem – both in North Carolina – believes the research to be the first of its kind.
“This is the first long-term study to compare the safety and effectiveness of high-frequency and traditional SCS therapy for back and leg pain,” he explains.
Scientists examined 171 patients with chronic back or leg pain, of whom 90 received HF10 therapy and 81 were treated with traditional SCS.
After 3 months, researchers found 85% of back pain and 83% of leg patients receiving HF10 therapy reported a 50% reduction in pain or greater. These patients also reported no experience of paresthesia.
In contrast, patients undergoing SCS reported less effective results. Only 44% of back pain patients and 56% leg patients experienced a minimum 50% reduction in pain.
The study ran over a 12-month period and found HF10 to be more effective compared with traditional SCS. More than half of the HF10 sample group reported being “very satisfied” with the outcome, compared with just 32% of patients who received traditional SCS.
Prof. Kapural hopes this research will be an important step toward treating chronic pain.
SCS represents an alternative for those patients who wish to avoid surgery or drugs such as opioids. According to a 2011 report, at least 100 million adult Americans suffer from chronic pain. In the same report, it was also estimated that chronic pain costs society between $500-635 billion a year.
Dr. Hanna has many years of experience performing SCS procedures for chronic pain patients. To learn if this procedure might be right for you, please make an appointment with Dr. Hanna at the Florida Spine Institute in Clearwater, FL. His contact information can be found here.
by admin | Aug 2, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Gender and estrous cycle influences on behavioral and neurochemical alterations in adult rats neonatally administered ketamine
VCM Borella, MV Seeman, RC Cordeiro… – Developmental …, 2015
Abstract Neonatal NMDA receptor blockade in rodents triggers schizophrenia-like
alterations during adult life. Schizophrenia is influenced by gender in age of onset,
premorbid functioning and course. Estrogen, the hormone potentially driving the gender …
Hypothalamic, thalamic and hippocampal lesions in the mouse MCAO model: potential involvement of deep cerebral arteries?
M El Amki, T Clavier, N Perzo, R Bernard, PO Guichet… – Journal of Neuroscience …, 2015
… Anesthetic methods in rodent models of cerebral ischemia impact the infarct volume. In
experimental models developed in rodents, the most used anesthetics are the volatile ones such
as isoflurane or halothane and intraperitoneal (ip) ketamine or barbiturates. …
Targeting the CD80/CD86 costimulatory pathway with CTLA4‐Ig directs microglia toward a repair phenotype and promotes axonal outgrowth
A Louveau, V Nerrière‐Daguin, B Vanhove… – Glia, 2015
… Male LEWIS 1A rats were anesthetized by intramuscular injection of 2% Rompun and 50mg/mL
ketamine (1.6 mL/kg) (PanPharma). … Twenty-eight days after transplantation, grafted-male Lewis
1A rats were deeply anesthetized with Rompun-ketamine (1:4) at 1 mg/kg (ip). …
[PDF] Anti-nociceptive effects of taurine and caffeine in sciatic nerve ligated wistar rats: involvement of autonomic receptors
W Abdulmajeed, BV Owoyele – Journal of African Association of Physiological …, 2015
… (St. Louis MO, USA) while propranolol and prazosin were products of Namco
Chemicals, Amritsr, India. Normal saline and ketamine were purchased from Momrota
pharmacy, opposite University of Ilorin Teaching Hospital’s gate. …
Two Cellular Hypotheses Explaining Ketamine’s Antidepressant Actions: Direct Inhibition and Disinhibition
OH Miller, JT Moran, BJ Hall – Neuropharmacology, 2015
Abstract A single, low dose of ketamine has antidepressant actions in depressed patients
and in patients with treatment-resistant depression (TRD). Unlike classic antidepressants,
which regulate monoamine neurotransmitter systems, ketamine is an antagonist of the N- …
Effect of Piperine on Liver Function of CF-1 albino Mice.
JR Peela, SD Kolla, F Elshaari, F Elshaari, H El Awamy… – Infectious disorders drug …, 2015
… with high fat diet. These mice were anaesthetized with ketamine and halothane and
blood was drawn from each mouse before the study and after three weeks by
cardiocentesis. Serum transaminases (alanine aminotransferase …
[PDF] Correlation between anti-HBs and immunostimulatory cytokines following hepatitis B vaccination in mice
OU Peter, PO OKONKWO, OO John, A Dorathy – 2015
… AM daily. All mice were acclimatized for two weeks. Diazepam injection (Valium,
Roche, USA), and ketamine injection (Ketalar, Popular Pharmaceuticals, Bangladesh)
were procured from Pax Pharmacy, Onitsha. Hepatitis B …
Phosphodiesterase‐4D: an enzyme to remember
R Ricciarelli, E Fedele – British Journal of Pharmacology, 2015
… enzyme isoform is localized in brain regions associated with emesis (eg area postrema and
nucleus of the solitary tract; Cherry and Davis, 1999; Lamontagne et al, 2001; Mori et al, 2010)
and its deletion in transgenic mice reduced the xylazine/ketamine-induced anaesthesia, a …
The effects of tacrolimus on the activity and expression of tissue factor in the rat ovary with ischemia–reperfusion induced injury
UV Ustundag, S Sahin, K Ak, I Keskin… – Reproductive Biology, 2015
… the ovaries. The rats were anesthetized with a combination of ketamine hydrochloride
(60 mg/kg ip.) and xylazine (5 mg/kg ip.). Supplementary injections of ketamine
hydrochloride were given when needed. After anesthesia …
Novel Rat Model for Neurocysticercosis Using Taenia solium
MR Verastegui, A Mejia, T Clark, CM Gavidia… – The American Journal of …, 2015
… Before intracranial inoculation, the rats were anesthetized with 70 mg/kg of ketamine plus
11 mg/kg of xylazine. … Animals were euthanized after being anesthetized with a mixture of
100 mg/kg of ketamine, 10 mg/kg of xylazine, and 3 mg/kg of tramadol. …
Photo of the Day: Low-dose Ketamine Infusions
A Katz – Emergency Medicine News, 2015
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. … This blog serves as a bulletin board for …
[HTML] Impact of Anesthesia Protocols on In Vivo Bioluminescent Bacteria Imaging Results
T Chuzel, V Sanchez, M Vandamme, S Martin, O Flety… – PLOS ONE, 2015
… S. aureus Xen36 strain. Bioluminescence imaging was performed on mice
anesthetized by either ketamine/xylazine (with or without oxygen supplementation),
or isoflurane carried with air or oxygen. Total flux emission was …
Sedative and Anxiolytic Agents
SI Ganzberg, S Wilson – Oral Sedation for Dental Procedures in Children, 2015
… The salient fea- tures of nitrous oxide, chloral hydrate, meperidine, midazolam, antihista- mines,
and ketamine are discussed in relation to sedating children for dental procedures. … Studies
using ketamine administered orally have resulted in mixed results. …
[HTML] Fractionated Radiation Exposure of Rat Spinal Cords Leads to Latent Neuro-Inflammation in Brain, Cognitive Deficits, and Alterations in Apurinic Endonuclease 1
MAS Kumar, M Peluso, P Chaudhary, J Dhawan… – PLOS ONE, 2015
… Ethics Statement. All exposures to radiation were done under ip anesthesia of xylazine/ ketamine
mixture- 4.3–5 ml per rat (male, Wistar strain) for an average weight of 540–600 gms (80 mg/kg
body weight of ketamine and 8 mg/ kg body weight of xylazine in PBS). …
Combinations of dexmedetomidine and alfaxalone with butorphanol in cats: application of an innovative stepwise optimisation method to identify optimal clinical doses …
C Adami, T Imboden, AE Giovannini, C Spadavecchia – Journal of Feline Medicine …, 2015
… anaesthesia. Commonly used protocols often include an a 2 -adrenoreceptor agonist
to produce reliable sedation, an opioid derivative to provide some analgesia, and
ketamine owing to its anaesthetic and analgesic effects. …
[HTML] Development of Animal Models of Local Retinal DegenerationAnimal Models of Local Retinal Degeneration
H Lorach, J Kung, C Beier, Y Mandel, R Dalal, P Huie… – … Ophthalmology & Visual …, 2015
… Animal facility. For surgeries, animals (P35–P50) were anesthetized with ketamine
(75 mg/kg) and Xylazine (5 mg/kg), delivered by intramuscular injection. Subretinal
implantations were performed as previously described. 31 …
[HTML] Following specific podocyte injury captopril protects against progressive long term renal damage
YS Zhou, IA Ihmoda, RG Phelps, COS Bellamy… – F1000Research, 2015
… VD DOM02, made by Orion Pharma, supplied by Henry Schein Medical) and 100mg/ml
ketamine (Vetalar) (Ref. … Terminal blood samples were collected at week 8 from intraperitoneally
anaesthetised animals (injected with medetomidine and ketamine). …
Clinical Sedation Regimens
S Wilson – Oral Sedation for Dental Procedures in Children, 2015
Page 74. Clinical Sedation Regimens Stephen Wilson S. Wilson, DMD, MA, PhD
Division of Pediatric Dentistry, Department of Pediatrics, Cincinnati Children’s Hospital
Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 …
Electrocardiogram reference intervals for clinically normal wild-born chimpanzees (Pan troglodytes)
R Atencia, L Revuelta, JD Somauroo, RE Shave – American Journal of Veterinary …, 2015
… Immediately before the examination procedures, body weight was estimated.
Chimpanzees were anesthetized by administration of a combination of ketamine
hydrochloride a (5 mg/kg) and medetomidine b (50 μg/kg). Anesthetic …
Deep Sedation and GA
SI Ganzberg – Oral Sedation for Dental Procedures in Children, 2015
… When an anesthesia machine capable of delivering sevoflurane is not available, as is typical
is most dental offices,“induction” is most commonly provided with an intramuscular injection of
ketamine and midazolam with or without an anticholinergic, ie, such as glycopyr- rolate or …
Radiofrequency Ablation (RFA)
In-utero radiofrequency ablation in fetal piglets: lessons learned
OO Olutoye, AN Gay, F Sheikh, AC Akinkuotu… – Journal of Pediatric Surgery, 2015
Methods 90 day gestation Yorkshire piglets (term 115 days) were subjected to RFA of the
chest and abdominal viscera under various temperatures and wattages. The extent of tissue
damage was determined by NADPH diaphorase histochemistry. Results Tyne …
Strain echocardiographic assessment of left atrial function predicts recurrence of atrial fibrillation
SI Sarvari, KH Haugaa, TM Stokke, HZ Ansari, IS Leren… – Eur Heart J Cardiovasc …, 2015
… Of these, 30 had not while 31 had recurrence of AF after radiofrequency ablation (RFA). Twenty
healthy individuals were included for comparison. … For patients with symptomatic drug-refractory
AF, radiofrequency ablation (RFA) has become an important therapy option. …
[HTML] Current management of patients with hepatocellular carcinoma
T Kanda, S Ogasawara, T Chiba, Y Haga, M Omata… – World J Hepatol, 2015
… of HCC. Many HCC patients are treated with surgical resection and radiofrequency
ablation (RFA), although these modalities should be considered in only selected
cases with a certain HCC number and size. Although there …
PP. 26.17: OUR CLINICAL EXPERIENCE WITH COMBINATION THERAPY OF OLMISARTAN AND AMLODIPINE IN THE TREATMENT OF RESISTANT …
T Chakalaa-Yancheva, S Tisheva, A Qnakieva… – Journal of Hypertension, 2015
… In all patients MRA excluded new or progression of pre- existing low grade renal artery stenosis
as well as focal aneurysms at the sites of radiofrequency ablation. In none of the patients new
segmental perfusion deficits in either kidney were detected on MRI. …
Multiscale Tetrahedral Meshes for FEM Simulations of Esophageal Injury
LA Neves, E Pavarino, MP Souza, CR Valencio… – Computer-Based Medical …, 2015
… [3] OJ Eick and D. Bierbaum, “Tissue temperature- controlled radiofrequency ablation,” Pacing
and clinical electrophysiology, vol. … [4] MO Siegel, DM Parenti, and GL Simon, “Atrialesophageal
fistula after atrial radiofrequency catheter ablation,” Clinical infectious diseases, vol. …
The meaning of gross tumor type in the aspects of cytokeratin 19 expression and resection margin in patients with hepatocellular carcinoma
SC Gong, MY Cho, SW Lee, SH Kim, MY Kim, SK Baik – Journal of Gastroenterology …, 2015
… From March 2012 to December 2014, 87 patients with HCC underwent surgical treatment including
intraoperative radiofrequency ablation at Wonju Severance Christian Hospital, Wonju, Korea.
Among them, 75 patients who underwent only hepatectomy were enrolled in …
Impact of catheter ablation with remote magnetic navigation on procedural outcomes in patients with persistent and long-standing persistent atrial fibrillation
Q Jin, S Pehrson, PK Jacobsen, X Chen – Journal of Interventional Cardiac …, 2015
… venous anatomy, left atrial (LA) volume, procedure time, mapping plus ablation time,
radiofrequency (RF) abla … CFAEs at the right atrium were not mapped and ablated in this study.
Although PVAI and CFAE ablation time were calculat- ed separately, CFAE ablation time did …
The role of AEG-1 in the development of liver cancer
CL Robertson, J Srivastava, D Rajasekaran, R Gredler… – Hepatic Oncology, 2015
… by rapid growth and early vascular invasion and thus the incidence and mortality of the disease
run in parallel [1,3]. Standard treatment options for patients afflicted with localized forms of the
disease include surgical resection, radiofrequency ablation or liver transplantation [4–7 …
Unexpected Findings in the Left Atrium of a Patient with a Paravalvular Mitral Leak
FS Silva, CA Barreiros, MC Antunes, ÂL Nobre – Journal of Cardiothoracic and …, 2015
… described including catheter-based cardiac interventions (eg valvular procedures, coronary
intervention, radiofrequency ablation), endocarditis, myocardial infarction and blunt cardiac
trauma.1 There are also cases of spontaneous dissection 2,10-11 occurring in patients with …
[PDF] Typical chest pain and precordial leads ST-elevation in patients with pacemakers-are we always looking at an acute myocardial infarction?
MM Ostojić, TS Potpara, MM Polovina, MM Ostojić… – Vojnosanitetski pregled, 2015
… ECG changes occurred due to pericardial re- action following two interventions: pacemaker
implantation a month before and radiofrequency catheter ablation of AV junction two weeks
before presentation in Emergency De- partment. Conclusion. …
[PDF] AB10-06
RC ABLATION – Heart Rhythm, 2015
Methods: The clinical features including freedom from AF/atrial tachycardia (AT) recurrence
as outcome after RFCA were compared between women and men in 1: 1 age, AF type,
duration of AF (±1 year) matched manner. Subgroup analysis was performed in categories …
MULTI-POLE SYNCHRONOUS PULMONARY ARTERY RADIOFREQUENCY ABLATION CATHETER
S Chen – US Patent 20,150,201,988, 2015
Abstract: A multi-pole synchronous pulmonary artery radiofrequency ablation catheter may
comprise a control handle, a catheter body and an annular ring. One end of the catheter
body may be flexible, and the flexible end of the catheter body may be connected to the …
Diagnostic and Interventional Endoscopy
Y Tomizawa, I Waxman – Atlas of Esophageal Surgery, 2015
… previous ablation zone. Ablation is repeated until the entire length of disease has
received radiofrequency energy (Fig. 3.15). After the entire lesion is ablated, the
guidewire, ablation catheter, and endoscope are removed. For focal …
[HTML] Osteoid osteoma masquerading tubercular arthritis or osteomyelitis on MRI: Case series and review of literature
JP Singh, S Srivastava, D Singh – Indian Journal of Radiology and Imaging, 2015
… periostitis. The patient underwent CT-guided biopsy and radiofrequency ablation. The …
effusion. A CT-guided radiofrequency ablation (RFA) [Figure 10]C was performed and
the patient remained symptom-free at 20 months follow-up. Figure …
Hybrid Transthoracic Esophagectomy
B Borraez, MG Patti – Atlas of Esophageal Surgery, 2015
… hernia, 11, 12 Schatzki’s ring, 12, 13 sliding hiatal hernia, 10, 11, 46 squamous cell cancer, 19
Zenker’s diverticulum, 15, 97 Barrett’s esophagus esophagectomy, 151, 152 focal nodular lesion,
25, 27 proximal resection margin, 141, 147 radiofrequency ablation, 23, 29 salmon …
PP. 26.16: CAN AN HOSPITAL ADMISSION MODIFY THE COURSE OF PATIENTS WITH RESISTANT HYPERTENSION?.
J Ribeiro, A Correia, R Ferreira, P Morgado, JM Bastos… – Journal of Hypertension, 2015
… In all patients MRA excluded new or progression of pre- existing low grade renal artery stenosis
as well as focal aneurysms at the sites of radiofrequency ablation. In none of the patients new
segmental perfusion deficits in either kidney were detected on MRI. …
Perspectives on the modern management of non-valvularatrial fibrillation: non-valvular af
R Gopal, MH Tayebjee – SA Heart, 2015
… catheters and the development of balloon based or circular ablation catheters with multiple
ablation electrodes that can be applied to the pulmonary vein antrum to isolate pulmonary veins
and ablate left atrial substrate(44,17) (Figures 1 a,b,c). Both radiofrequency catheter and …
APPARATUS AND METHODS FOR CLOSING VESSELS
BB Hill, J Hong, W Qi – US Patent 20,150,201,947, 2015
… The following is a list of one or more advantages that may be achieved using the apparatus and
methods described herein, eg, as compared to endovenous laser, radiofrequency ablation
technologies, and other methods that destroy the vein by applying chemicals or applying …
Fluorescence Imaging Systems (PDE, HyperEye Medical System, and Prototypes in Japan)
T Ishizawa, N Kokudo – Fluorescence Imaging for Surgeons: Concepts and …, 2015
Hepatocellular Carcinoma Precursor Lesions
ML Smith – Surgical Pathology of Liver Tumors, 2015
Chronic Regional Pain Syndrome (CRPS/RSD)
A scoring rule-based truthful demand response mechanism
K Hara, T Ito – Computer and Information Science (ICIS), 2015 IEEE/ …, 2015
… Therefore, conventional scoring rule with single item, such as Brier score [5] is of no use for this
mode. In order to rightfully incentivize the CA to make their prediction of device shifting for multiple
items rightfully; the continuous ranked probability score (CRPS) is applied [13]. …
[PDF] Why Attackers Win: On the Learnability of XOR Arbiter PUFs
F Ganji, S Tajik, JP Seifert – 2015
… These attacks, as cost-effective approaches, can clone the challenge-response behavior of an
arbiter PUF by collecting a subset of challenge-response pairs (CRPs). … Moreover, when applying
current ML attacks, the maximum number of CRPs required for Page 3. …
[PDF] A Multivariate Modeling Approach for Generating Ensemble Climatology Forcing for Hydrologic Applications
S Khajehei – 2015
Page 1. Portland State University PDXScholar Dissertations and Theses Dissertations and Theses
Spring 7-21-2015 A Multivariate Modeling Approach for Generating Ensemble Climatology Forcing
for Hydrologic Applications Sepideh Khajehei Portland State University …
[HTML] Oil Palm Leaf and Corn Stalk–Mechanical Properties and Surface Characterization
Z Daud, MZM Hatta, H Awang – Procedia-Social and Behavioral Sciences, 2015
… Bhaduri et al., 1995; BK Bhaduri, A. Day, SB Mondal, .SK Sen; Ramie hemicelluloses as beater
additive in a paper making from jute-stick kraft pulp. Industrial Crps and Products, 4 (1995), pp.
79–84. Daud et al., 2013; Z. Daud, MZM Hatta, ASM Kassim, AM Aripin, H. Awang; …
[HTML] Nerve injury and neuropathic pain–a question of age
M Fitzgerald, R McKelvey – Experimental Neurology, 2015
… Furthermore several complex pain syndromes (eg CRPS) that emerge in older children are
associated with little or no measurable disease activity or inflammation at the time of presentation
and are clinically defined as ‘functional’ or ‘medically unexplained’ (Bromberg et al …
Acute acalculous cholecystitis and cardiovascular disease: a land of confusion
M Tana, C Tana, G Cocco, G Iannetti, M Romano… – Journal of Ultrasound, 2015
… Most common clinical onset was represented by fever (70 %) in opposite to abdominal pain
which occurred in 20 % of patients. 8/10 patients were male. Elevated CRPs, leukocytosis
(60 %), and elevated aminotransferase (30 %) occurred frequently. …
[PDF] Characterizing the Stability of Okun’s Law during Economic Recessions by cross-Recurrence Plot and Rolling Regression
J Gao, Y Cao
… 2 n xx x , , , and 1 2 n yy y , , , , which, for concreteness, may be equated to unemployment and
production data, one obtains CRPs (Marwan & Kurths 2002; Marwan, et al. 2007). … 4, No. 3 ~ 5 ~
Figure 2. Cross recurrence plots (CRPs); notice the correspondence of vertical …
[PDF] Use of Hidden Markov Mobility Model for Location Prediction and Biclustering for Cache Replacement in MANET
BD Shelar, MDK Chitre
… But these policies give satisfactory performance for stable user and prove inefficient for mobile
user which free to change his direction. Direction and Distance Based CRPs think for the mobile
nature of user. … Prediction Based CRPs analyze the history of users’ movements. …
Field Deployable Chemical Redox Probe for Quantitative Characterization of Carboxymethylcellulose Modified Nano Zerovalent Iron
D Fan, S Chen, RL Johnson, PG Tratnyek – 2015
Page 1. 1 2 Field Deployable Chemical Redox Probe for Quantitative Characterization of 3
Carboxymethylcellulose Modified Nano Zerovalent Iron 4 5 6 Dimin Fan, Shengwen Chen, Richard
L. Johnson, and Paul G. Tratnyek* 7 8 Institute of Environmental Health 9 …
Technical innovations for small-scale producers and households to process wet cassava peels into high quality animal feed ingredients and aflasafe™ substrate
I Okike, A Samireddypalle, L Kaptoge, C Fauquet… – Food Chain, 2015
Headache and Pain
R Baron, A May – 2015
Molecular Biology of Retinoblastoma
SD Walter, JW Harbour – Recent Advances in Retinoblastoma Treatment, 2015
… Rb directly inhibits E2Fs by binding and masking the transactivation domain, and it also recruits
chromatin remodeling proteins (CRPs) that alter local chromatin structure into a confirmation
that is not permis- sive for transcription.(b) When Rb is hyperphosphory- lated, it does …
[PDF] Guidelines for Neuromusculoskeletal Infrared Thermography Sympathetic Skin Response (SSR) Studies
DO Getson, S Govindan, J Uricchio, T Bernton…
… Assessment of patients with presumptive Complex Regional Pain Syndrome (CRPS) Type I or
II – formally known as Reflex Sympathetic Dystrophy (RSD), Thoracic Outlet Syndrome,
Vaso-motor Headache and Barre’-Leiou Syndrome. … CRPS: Current Diagnosis and Therapy. …
[HTML] Thread: Advances in treatment of post-amputation phantom limb pain
W Young, J Date
… reviewed fifteen papers reporting mirror therapy to treat upper limb function and concluded that
most of the studies were weak methodologically and that the results suggest possible benefit
in patients after stroke and complex regional pain syndrome (CRPS) but the …
[PDF] Guidelines For Dental-Oral And Systemic Health Infrared Thermography
M Brioschi, H Usuki, BSN Jan Crawford, P Steed…
… c. Relevant risk factors for inflammation or vasomotor instability: prior history of RSD
or CRPS, trauma, fracture, repetitive use, vibration syndrome, peripheral neuropathy,
spinal pathology, radiculopathy, vasomotor headache, Page 4. …
[HTML] Chronic Pain Medication & Treatment Guide
AR Guide
… cord injuries. It may develop months or years after injury or damage to the CNS.
This also includes conditions such as chronic headaches, fibromyalgia, and Complex
Regional Pain Syndrome (CRPS). Tailoring selection of …
[DOC] WORKSHOP ON BEST PRACTICE METHODS FOR ASSESSING THE IMPACT OF POLICY ORIENTED RESEARCH SUMMARY AND RECOMMENDATIONS FOR …
F Place, P Hazell
WORKSHOP ON BEST PRACTICE METHODS FOR ASSESSING THE IMPACT OF
POLICY ORIENTED RESEARCH. SUMMARY AND RECOMMENDATIONS FOR
THE CGIAR. Frank Place and Peter Hazell. WORKSHOP ON …
CRPS A contingent hypothesis with prostaglandins as crucial conversion factor
PHE van der Veen – Medical Hypotheses, 2015
Abstract CRPS is an acute pain disease expressed as chronic pain with a severe loss of
tissue and function. CRPS usually occurs after minor injuries and then progresses in a way
that is scarcely controllable, or completely uncontrollable. This article addresses the …
Vitamin C to Prevent Complex Regional Pain Syndrome in Patients With Distal Radius Fractures: A Meta-Analysis of Randomized Controlled Trials
N Evaniew, C McCarthy, YV Kleinlugtenbelt, M Ghert… – Journal of orthopaedic …, 2015
… Collapse Box Abstract. Objective: To determine whether vitamin C is effective in preventing
complex regional pain syndrome (CRPS) in patients with distal radius fractures. … 2 CRPS has been
previously referred to as causalgia, reflex sympathetic dystrophy, and algodystrophy. 3. …
Injury of the corticoreticular pathway in patients with mild traumatic brain injury: A diffusion tensor tractography study
HD Lee, SH Jang – Brain Injury, 2015
… Figure 1. Diffusion tensor tractography for the corticoreticular pathway (CRP): a normal control
subject (44 year-old, female), type A = the CRPs showed narrowing, although integrity was
preserved from the premotor cortex to the reticular formation of the medulla, type B = the …
[PDF] Plasma Exchange Therapy in Patients with Complex Regional Pain Syndrome
E Aradillas, RJ Schwartzman, JR Grothusen, A Goebel – Pain Physician, 2015
Page 1. Background: Complex regional pain syndrome (CRPS) is a severe chronic
pain condition that most often develops following trauma. … These patients were then
placed on Complex regional pain syndrome (CRPS) is a …
Controversial Pain Syndromes of the Arm: Pathogenesis and Surgical Treatment of Resistant Cases
A Wilhelm – 2015
[PDF] Mixture EMOS model for calibrating ensemble forecasts of wind speed
S Baran, S Lerch – arXiv preprint arXiv:1507.06517, 2015
… The most popular scoring rules are the logarithmic score, that is the negative logarithm of the
predictive PDF evaluated at the verifying observation and the continuous ranked probability score
(CRPS; Gneiting and Raftery, 2007; Wilks, 2011). … CRPS(F, x) := ∫ ∞ …
[PDF] Targeted Ultrasound-Guided Double Catheters (Infraclavicular-Brachial Plexus, Median Nerve) Facilitate Hand Rehabilitation with Superb Analgesia and Motor …
AE Holman, B Sharma, VE Modest – Open Journal of Anesthesiology, 2015
… http://creativecommons.org/licenses/by/4.0/ Abstract A 44-year-old male who suffered a
crush-degloving hand injury complicated by Complex Regional Pain Syndrome (CRPS) type
I was scheduled for operative hand manipulation and inpatient physi- otherapy. …
Leads for neurostimulation and methods of assembling same
A Raines – US Patent 9,084,882, 2015
… As used herein the term “complex regional pain syndrome” or “CRPS” refers to painful
conditions that usually affect the distal part of an upper or lower extremity and are
associated with characteristic clinical phenomena. CRPS …
[PDF] Identification and characterization of a novel family of cysteine-rich peptides (MgCRP-I) from Mytilus galloprovincialis
M Gerdol, N Puillandre, G De Moro, C Guarnaccia… – Genome Biology and …, 2015
… encoding peptides with unique chemico-physical properties and/or sequence patterns. Actually,
cysteine-rich peptides (CRPs) encompass a large and widespread group of secreted … plants
(Gruber, et al. 2007; Marshall, et al. 2011; Taylor, et al. 2008). Invertebrate CRPs are …
Peri‐infarct reorganization of an injured corticoreticulospinal tract in a patient with cerebral infarct
SH Jang, J Lee, HD Lee – International Journal of Stroke, 2015
… (c) The CRPs are descended through the subcortical white matter in two age-matched normal
control subjects. Letter to the editor © 2015 World Stroke Organization E62 Vol 10, August 2015,
E62–E63 Page 2. References 1 Yeo SS, Chang MC, Kwon YH, Jung YJ, Jang SH. …
Fibromyalgia
Depressive-like symptoms in a reserpine-induced model of fibromyalgia in rats
A Blasco-Serra, F Escrihuela-Vidal, EM González-Soler… – Physiology & Behavior, 2015
Abstract Since the pathogenesis of fibromyalgia is unknown, treatment options are limited,
ineffective and in fact based on symptom relief. A recently proposed rat model of
fibromyalgia is based on central depletion of monamines caused by reserpine …
Is there any link between joint hypermobility and mitral valve prolapse in patients with fibromyalgia syndrome?
E Kozanoglu, IC Benlidayi, RE Akilli, A Tasal – Clinical Rheumatology, 2015
Abstract The objective of the present study is to determine whether benign joint
hypermobility syndrome (BJHS) modifies the risk of mitral valve prolapse (MVP) in patients
with fibromyalgia (FM). Female patients fulfilling the 1990 American College of …
[HTML] Calibration and Validation of the Dutch-Flemish PROMIS Pain Interference Item Bank in Patients with Chronic Pain
MHP Crins, LD Roorda, N Smits, HCW de Vet… – PLOS ONE, 2015
… as pain that persists beyond the normal tissue healing time, in which the most prevalent pain
is musculoskeletal pain, with prevalence varying from 30–40% for low back pain, 15–20% for
shoulder- and neck pain, 10–15% for chronic widespread pain and 2% for fibromyalgia [3,4 …
Assessment of response bias in neurocognitive evaluations
DA Carone – NeuroRehabilitation, 2015
… survey data of neuropsychologists show that the base rates of malingering or symptom
exaggeration are much higher (29% to 41%) in settings where patients are seeking financial
compensation or disability and in patient groups (ie, concussion, fibromyalgia, chronic fatigue …
[PDF] SENSE OF WELL-BEING IN PATIENTS WITH FIBROMYALGIA. AEROBIC EXERCISE PROGRAM IN A MATURE FOREST: A PILOT STUDY
S Lopez-Pousa, GB Pagès, S Monserrat-Vila
ABSTRACT Background and objective: Most patients with fibromyalgia benefit from different
forms of physical exercise. Studies show that exercise can help restore the body’s
neurochemical balance and that it triggers a positive emotional state. So, regular exercise …
[HTML] Miller Chiropractic & Laser Treatment Center
D Emery
… Acta Medica Academica 2013;42(1):46-54. doi: 10.5644/ama2006-124.70. Study Finds
Chiropractic Beneficial for Fibromyalgia. A new study from Egypt reports that chiropractic care
can be an effective treatment strategy for fibromyalgia treatment with chiropractic care. …
[PDF] Cost-effectiveness of 40-hour versus 100-hour vocational rehabilitation on work participation for workers on sick leave due to subacute or chronic musculoskeletal …
TT Beemster, JM van Velzen, CAM van Bennekom… – Trials, 2015
… as follows: 1) individuals of working age (18 to 65 years); 2) suffering from subacute (6 to 12 weeks)
or chronic (>12 weeks) nonspecific musculoskeletal pain such as back, neck, shoulder,
widespread pain, Whiplash Associated Disorder (WAD I or II), or fibromyalgia; 3) having …
Peer-Reviewed Abstracts
D Avans – Research Quarterly for Exercise and Sport, 2015
… Fine motor control knowingly declines with age and certain diseases such as fibromyalgia and
cerebral palsy (Perez-de-Heredia-Torres, 2013). … Research of this nature could also be translated
to diseased populations such as those with fibromyalgia or diabetes. …
Gastro-protective and Anti-stress Efficacies of Monomethyl Fumarate and a Fumaria indica Extract in Chronically Stressed Rats
A Shakya, UK Soni, G Rai, SS Chatterjee, V Kumar – Cellular and Molecular …, 2015
… are some of the major symptoms of numerous, if not all, chronic inflammatory diseases
accompanying central sensitivity syndromes (Yunus 2008 ), and it is now well recognized that
cytokine and immune system abnormalities are the root cause of fibromyalgia and other central …
[PDF] Mechanisms of action of balneotherapy in rheumatic diseases
A Fioravanti, S Cheleschi – IV CIBAP BOÍ 2015
… Anti-inflammatory aspects Recent studies have shown a reduction of circulating levels of
Prostaglandin E2 (PGE2) and Leukotriene B4 (LTB4), important mediators of inflammation and
pain, in patients suffering from OA or fibromyalgia who undergo mud-packs or …
Determinants of Patient Satisfaction in an Academic Rheumatology Practice.
JH Ku, A Danve, H Pang, D Choi, JT Rosenbaum – Journal of clinical rheumatology: …, 2015
… 95% CI, -15.25 to -3.25), arthralgia (β = -8.67; 95% CI, -16.60 to -0.74), myalgia (β = -8.67; 95%
CI, -16.60 to -0.74), gout (β = -7.5; 95% CI, -14.13 to -0.89), ankylosing spondylitis (β = -5.20;
95% CI, -9.65 to -0.75), pain (β = -4.62; 95% CI, -8.43 to -0.81), fibromyalgia (β = -4.62; 95 …
Method and Apparatus for Diagnosing and Assessing Centralized Pain
JB Hargrove – US Patent 20,150,201,879, 2015
… Because of this emerging understanding, the role of CS is increasingly being shown to be
pathological in seemingly unrelated chronic pain conditions and syndromes including fibromyalgia,
complex regional pain syndrome, phantom pain, and migraine headaches. …
FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS
E Berry, Y Avraham, J Katzhendler, J Mograbi… – US Patent 20,150,202,179, 2015
… Abstract: The invention provides fatty acid derivatives for use in a method of treatment of at least
one disease, disorder or condition selected from anxiety, depression, conditions associated
menopause, stress, bipolar disorder, neuropathic pain and fibromyalgia. …
ANTIBODIES TO IL-6 AND THEIR USES
A Rajpal, MN Devalaraja, K Toy, L Yang, H Huang… – US Patent 20,150,203,574, 2015
… The term “fibromyalgia” is also known as fibromyalgia syndrome. The American College
of Rheumatology (ACR) 1990 classification criteria for fibromyalgia include a history
of chronic, widespread pain for more than three months …
Impact of Gender-Based Aggression on Women’s Mental Health in Portugal
M Reis, L Ramiro, MG de Matos – … Mental Health: Resistance and Resilience in …, 2015
… The rate was even higher for women who had experienced non-partner sexual violence (WHO,
2013). Health effects can also include headaches, back pain, abdominal pain, fibromyalgia,
gastrointestinal disorders, limited mobility, and poor overall health (WHO, 2013). …
Pain 2014 Refresher Courses: 15th World Congress on Pain
SN Raja, CL Sommer – 2015
Restless Legs Syndrome: The Devil Is in the Details
PJ Sampognaro, RE Salas, A Kalloo, C Gamaldo – Sleepy or Sleepless: Clinical …, 2015
… medical conditions Restless legs syndrome (Willis-Ekbom disease) Renal failure Periodic limb
movement disorder Anemia REM sleep behavior disorder (RBD) Peripheral neuropathy
Obstructive sleep apnea syndrome (OSAS) Rheumatoid arthritis Fibromyalgia Attention deficit …
[PDF] Dermatologic Extrahepatic Manifestations of Hepatitis C
B Dedania, GY Wu – Journal of Clinical and Translational Hepatology, 2015
… cutanea tarda23 – Lichen planus33,35,36 – Sicca syndrome – Auto-antibody productions
(rheumatoid factor, cryoglobulins, anti-smooth muscle) – Glomerulonephritis12 C. Possible
association2,16 – Polyarthritis – Pruritus – Fibromyalgia – Chronic polyradiculoneuropathy – Lung …
PHOSPHATIDYLINOSITOL-3-KINASE C2 BETA MODULATORS AND METHODS OF USE THEREOF
E Skolnik, Z Li, S Srivastava – US Patent 20,150,204,846, 2015
… Exemplary IgE-mediated allergic disorders include, without limitation, allergic rhinitis,
allergic or atopic asthma, anaphylaxis, atopic dermatitis, eczema, hay fever,
fibromyalgia, and an immediate type hypersensitivity reaction. …
Psychological Interventions for the Management of Chronic Pain: a Review of Current Evidence
RS Kaiser, M Mooreville, K Kannan – Current Pain and Headache Reports, 2015
… A few of the many variants of this approach will be highlighted. Currently, cognitive
behavioral therapy (CBT) is a first-line psychological treatment for individuals with chronic
pain, such as back pain, headache, arthritis, and fibromyalgia [ 12 •]. …
by admin | Jul 7, 2015 | Uncategorized
Ketamine is a long known anesthetic agent that is still used for induction anesthesia in medicine today. It is also used off label for the treatment of various treatment-resistant diseases ranging from depression to various pain disorders. For the treatment of pain, intravenous ketamine has proven successful in countless case studies and numerous placebo-controlled clinical trials. Interestingly, ketamine has gained much attention in the media recently as a possible treatment for depression. Since originally reported as efficacious in certain cases of depression, it has proven successful in subtypes of this disease, like post-traumatic stress disorder (PTSD).
Although suicidality (suicidal thoughts) is commonly expected to accompany depression, this is not always the case. The two diseases are clinically different as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM). Interestingly, a recent clinical study aimed to assess the efficacy of intravenous (IV) ketamine for the treatment of suicidal cognition in symptomatic patients with treatment-resistant unipolar major depression. The patients that were entered into this trial had inadequate responses to more than three other antidepressant medications. Interestingly, there is currently no FDA-approved drug for the treatment of suicidality. A team of researchers from the University of Pittsburgh, Icahn School of Medicine at Mount Sinai, Baylor College of Medicine, and the Michael E. Debakey VA Medical Center conducted a placebo controlled clinical trial to evaluate the efficacy of intravenous ketamine for the treatment of suicidality. Fifty seven patients completed the trial and were assessed by the researchers using a composite index of explicit suicidal ideation. A psychoactive placebo, midazolam, was used.
The researchers published their findings in the journal of Depression and Anxiety. They found that the intravenous ketamine group had rapid reductions in suicidal cognition “over and above” the active placebo group. This finding could be critical for the development of an FDA-approved medication for the treatment of suicidality, a would-be first for this indication. The researchers concluded that their findings warrant further study into ketamine’s antisuicidal effects in higher-risk patients.
Intravenous ketamine is offered at the Florida Spine Institute by Dr. Ashraf Hanna’s clinical team. Dr. Hanna has achieved great success using IV ketamine for the treatment of many diseases that fail to respond adequately to conventional therapies. To find out if this therapy might be right for you, please make an appointment to see Dr. Hanna.
by admin | Jun 22, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Ketamine and Phencyclidine: the good, the bad and the unexpected
D Lodge, MS Mercier – British Journal of Pharmacology, 2015
ABSTRACT: The history of ketamine and phencyclidine from their development as potential
clinical anaesthetics, through drugs of abuse and animal models of schizophrenia to
potential rapidly acting antidepressants is reviewed. The discovery in 1983 of the NMDA …
Intra‐and postoperative low‐dose ketamine for adolescent idiopathic scoliosis surgery: a randomized controlled trial
R Minoshima, S Kosugi, D Nishimura, N Ihara, H Seki… – Acta Anaesthesiologica …, 2015
Background In this randomized controlled trial, we examined whether intra-and
postoperative infusion of low-dose ketamine decreased postoperative morphine
requirement and morphine-related adverse effects as nausea and vomiting after scoliosis …
Period Prevalence of Ketamine-Propofol Admixture “Ketofol” in the Operating Room among Anesthesia Providers at an Academic Medical Center
AN Olson, WR Rao, ME Marienau, NJ Smischney – Medical Science Monitor, 2015
BACKGROUND: The primary aim of this study was to determine the period prevalence of the
single-syringe ketamine-propofol admixture used for sedation and induction among
anesthesia providers during a 5-year period before and after educational sessions …
Electrochemiluminescence immunosensor for ketamine detection based on polyamidoamine-coated carbon dot film
Q Li, W Tang, Y Wang, J Di, J Yang, Y Wu – Journal of Solid State Electrochemistry, 2015
Abstract In this work, we reported the synthesis of water-soluble carbon dots (CDs) by a one-
step hydrothermal synthetic route using polyamidoamine (PAMAM) as platform and
passivant, where the formation of CDs capped with PAMAM and the surface passivation …
Letter to the editor: When what you see might not be what you get: prudent considerations of anesthetics for murine echocardiography
J Wu, J You, S Wang, Y Ye, X Wang, J Jia, Y Zou – American Journal of Physiology- …, 2015
… In their well- designed experiments, the authors compared four popular an- esthetic regimens
(ketamine-xylazine, ketamine alone, avertin, and isoflurane) used in mice during
echocardiographic mea- surement, with conscious state as a reference. …
Ketamine promotes inflammation through increasing TLR4 expression in RAW264. 7 cells
C Meng, Z Liu, G Liu, L Fu, M Zhang, Z Zhang, H Xia… – Journal of Huazhong …, 2015
Summery Ketamine (KTM), a N-methyl-D-aspartate (NMDA) receptor antagonist, was found
to has an anti-inflammatory effect, but some patients suffered from exacerbated pro-
inflammatory reactions after anesthesia with KTM. The present study was aimed to …
The effect of NMDA receptor antagonists and antidepressants on resting state in major depressive disorder
A Dutta – 2015
fMRI ; major depressive disorder ; resting state ; antidepressant ; lanicemine ; ketamine ; citalopram
; anterior cingulate cortex ; NMDA ; glutamate. … Ketamine and other NMDA antagonists have
improved MDD symptoms within 24 hours though the effects are short lasting. …
Assessing Measures of Suicidal Ideation in Clinical Trials with a Rapid-Acting Antidepressant
ED Ballard, DA Luckenbaugh, EM Richards, TL Walls… – Journal of Psychiatric …, 2015
… Received 22 April 2015, Revised 21 May 2015, Accepted 5 June 2015, Available online 16 June
2015. Highlights. • Clinical trials of ketamine and suicide will require appropriate measurement. •
We compared several suicide assessment measures in ketamine clinical trials. • …
d-Cycloserine
AR Durrant, U Heresco-Levy – Encyclopedia of Psychopharmacology, 2015
… of this concept became evident during the last decade when robust antidepressant effects
emerging within 2–4 h and lasting up to more than 2 weeks were obtained and replicated fol-
lowing intravenous administration of single sub-anesthetic doses of ketamine (Krystal et al. …
Depression: Response and Remission
SD Østergaard, GI Papakostas, M Fava – Encyclopedia of Psychopharmacology, 2015
… of this concept became evident during the last decade when robust antidepressant effects
emerging within 2–4 h and lasting up to more than 2 weeks were obtained and replicated fol-
lowing intravenous administration of single sub-anesthetic doses of ketamine (Krystal et al. …
Is pre-emptive administration of ketamine a significant adjunction to intravenous morphine analgesia for controlling postoperative pain? A randomized, double-blind, …
A Fiorelli, A Mazzella, B Passavanti, P Sansone… – … and Thoracic Surgery, 2015
OBJECTIVES To evaluate if the pre-emptive administration of ketamine would potentiate the
effect of intravenous morphine analgesia in the management of post-thoracotomy pain.
METHODS This was a unicentre, double-blind, placebo-controlled, parallel-group, …
Kappa-Opioid Agonists
E Opioid – 2015
… It is considered a precancerous condition. Ketamine … Synonyms Ketalar; Ketaset Definition
Ketamine is an FDA-approved medication for induction and maintenance of anesthesia
in adults. It is a phencyclidine derivative first synthetized in 1962. …
Investigation of the effects of stress on some liver enzymes (AST, ALT, ALP) in rats.
YG Gencer, A Çınar, B Comba – Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 2015
… was applied intraperitoneally (ip) to the experimental group. After 3 h, blood samples
were collected from both groups under ketamine anaesthesia, using appropriate
techniques. The control group serum AST, ALT, ALP values …
Back to the Future: Are Tumor-Targeting Bacteria the Next-Generation Cancer Therapy?
RM Hoffman – Gene Therapy of Solid Cancers, 2015
… 7. Anesthetic reagents (ketamine, xylazine, acepromazine maleate). 8. Kanamycin. 9. Nair. 10. …
1. Four-week-old female mice were anesthetized by a ketamine mixture (10 μl ketamine HCL,
7.6 μl xylazine, 2.4 μl acepromazine maleate, and 10 μl H 2 O) via sc injection. …
[PDF] The Protective Effect of Melatonin vs. Vitamin E in the Ischemic/Reperfused Skeletal Muscle in the Adult Male Rat Model
EA Mohamed – J Cytol Histol S, 2015
… All surgical procedures were performed under anesthesia with IP injection of
Ketamine hydrochloride (Ketame, Egyptian Int. Co. … After 2 hours of reperfusion, the
rats were sacrificed by Ketamine hydrochloride (100 mg/kg) [10]. …
[PDF] CORM2 protects from myocardial ischemia reperfusion injury via modulation of the inflammatory response and apoptosis
NR Hadi, FG Al-Amran, KA Muhsin, A Taher – Journal of Advanced Pharmacy …, 2015
… 2% vials (RompunTM, Bayer AG, Leverkusen, Germany), ketamine (Hikma, Jordan), ethanol
(Fluka, Switzerland) and normal saline (KSA). Rat (IL-1β), (IL- … Surgical LAD ligation The rats were
anesthetized by intraperitoneal injection with a mixture of ketamine and xylazine in a …
[HTML] Long-term correlation of the electrocorticogram as a bioindicator of brain exposure to ionizing radiation
LAA Aguiar, IMS Silva, TS Fernandes, RA Nogueira – Brazilian Journal of Medical and …, 2015
… The irradiation was carried out with the animals anesthetized with 10 mg/kg xylazine and 75
mg/kg ketamine administered intraperitoneally. … To record the ECoG, animals were anesthetized
with 10 mg/kg xylazine and 75 mg/kg ketamine administered intraperitoneally. …
[HTML] The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor
SM de Melo, S Bittencourt, EG Ferrazoli, CS da Silva… – PLOS ONE, 2015
… The animals were anesthetized via the ip injection of a ketamine (100 mg/kg) and xylazine
(10 mg/kg) solution (Syntec, 1356009 and 1720407) and fastened to a stereotaxic
instrument (David Kopf) equipped with a mouse adapter (Enlaup). …
[HTML] Intrarectal Lidocaine-Diltiazem-Meperidine Gel for Transrectal Ultrasound Guided Prostate Biopsy
F Imani, Y Moghaddam, RS Moharari, F Etezadi… – Anesthesiology and Pain …, 2015
… 4, 6) or bupivacaine as a single agent (7). These latter studies have suggested that rectal
administration of lidocaine gel is a safe, simple modality, without any discomfort for patients (8).
Not only local anesthetic agents but also intravenous anesthetic drugs (ketamine) (9) or …
[PDF] Alcohol Withdrawal Syndrome: Improving Outcomes Through Early Identification And Aggressive Treatment Strategies
AF Pizon – 2015
Page 1. June 2015 Volume 17, Number 6 Authors Joseph H. Yanta, MD Medical
Toxicology Fellow, Division of Medical Toxicology, Dept. of Emer- gency Medicine,
University of Pittsburgh Medical Center, Pittsburgh, PA Greg …
Radiofrequency Ablation (RFA)
Use of Contact Force Sensing Technology During Radiofrequency Ablation Reduces Recurrence of Atrial Fibrillation: A Systematic Review and Meta-Analysis
MR Afzal, J Chatta, A Samanta, S Waheed… – Heart Rhythm, 2015
ScienceDirect is phasing out support for older versions of Internet Explorer on Jan 12, 2016.
For the best product experience, we recommend you upgrade to a newer version of IE or
use a different browser: Firefox or Chrome. For additional information please see the …
Comparison of Surgical Resection and Radiofrequency Ablation for Hepatocellular Carcinoma: Take Care Not to Neglect Radiofrequency Technic and Device.
A Hocquelet, M Montaudon, P Balageas, N Frulio… – Annals of Surgery, 2015
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. … Skip Navigation Links Home > …
Effect of different ablation settings on acute complications using the novel irrigated multipolar radiofrequency ablation catheter (nMARQ)
T Deneke, P Müller, P Halbfaß, A Szöllösi, M Roos… – Journal of Cardiovascular …, 2015
Background: Single-shot ablation devices for pulmonary vein isolation (PVI) in patients with
symptomatic atrial fibrillation (AF) have been increasingly used in clinical practice. Objective:
A novel mapping-system integrated irrigated multipolar circular ablation catheter (nMARQ) …
Long-Term Effects of Ganglionated Plexi Ablation on Electrophysiological Characteristics and Neuron Remodeling in Target Atrial Tissues in a Canine Model
X Wang, M Zhang, Y Zhang, X Xie, W Wang, Z Li… – Circulation: Arrhythmia and …, 2015
… Long-Term Effects of Ganglionated Plexi Ablation on Electrophysiological Characteristics and
Neuron Remodeling in Target Atrial Tissues in a Canine Model. … Atrial electrophysiological
characteristics were examined before ablation, immediately and continuously after ablation. …
… to Letter From Bisbal et al Regarding,“Repeat Left Atrial Catheter Ablation: Cardiac Magnetic Resonance Prediction of Endocardial Voltage and Gaps in Ablation …
JL Harrison, C Sohns, NW Linton, R Karim, SE Williams… – Circulation: Arrhythmia and …, 2015
… Tolosana JM,; Arbelo E,; de Caralt TM,; Perea RJ,; Brugada J,; Mont L. CMR-guided
approach to localize and ablate gaps in repeat AF ablation procedure. JACC Cardiovasc
Imaging . 2014;7:653–663. doi: 10.1016/j.jcmg.2014.01.014. …
Pulmonary vein stenosis after pulmonary vein isolation using duty-cycled unipolar/bipolar radiofrequency ablation guided by intracardiac echocardiography
S Asbach, F Schluermann, L Trolese, M Langer… – Journal of Interventional …, 2015
Purpose Concerning rates of pulmonary vein (PV) stenosis were reported following PV
isolation (PVI) with a circular pulmonary vein ablation catheter (PVAC). As this may depend
on intraprocedural imaging, we evaluated the incidence of PV stenosis in patients …
Atrioventricular Block During Slow Pathway Ablation Entirely Preventable?
H Chen, M Shehata, W Ma, J Xu, J Cao, E Cingolani… – Circulation: Arrhythmia and …, 2015
… In a small percentage of cases of AVNRT, it may be necessary to ablate within the CS
with larger atrial potentials, however, ablation at the roof of the proximal CS carries
a high risk of AV nodal block during radiofrequency application. …
Is There Still a Role for CFAE Ablation in Addition to Pulmonary Vein Isolation in Patients with Paroxysmal and Persistent Atrial Fibrillation? A Meta-Analysis of 1,415 …
R Providência, PD Lambiase, N Srinivasan, GG Babu… – Circulation: Arrhythmia and …, 2015
… Is There Still a Role for CFAE Ablation in Addition to Pulmonary Vein Isolation in Patients with
Paroxysmal and Persistent Atrial Fibrillation? … We aimed to assess the impact of CFAE ablation
in addition to pulmonary vein isolation (PVI) in patients undergoing ablation for AF. …
Real-Time Contact Force Measurement A Key Parameter for Controlling Lesion Creation With Radiofrequency Energy
DC Shah, M Namdar – Circulation: Arrhythmia and Electrophysiology, 2015
… Low CF values are also advisable in the vicinity of already ablated sites, where the … for the
acquisition of reliable mapping information and achievement of stable ablation lesions … 183 gs)
as area under curve (red hatched zone) during short duration of radiofrequency (RF) energy …
Atrioventricular Nodal Block With Atrioventricular Nodal Reentrant Tachycardia Ablation
SJ Asirvatham, WG Stevenson – Circulation: Arrhythmia and Electrophysiology, 2015
… a relatively slow stable, junctional rhythm with consistent stable retrograde atrial conduction during
radiofrequency application. … of energy delivery, junctional rhythm may not be seen despite adequate
slow pathway ablation, and the operator may be inclined to ablate at more …
[HTML] Near-infrared spectroscopy integrated catheter for characterization of myocardial tissues: preliminary demonstrations to radiofrequency ablation therapy for atrial …
RP Singh-Moon, CC Marboe, CP Hendon – Biomedical Optics Express, 2015
Abstract Effects of radiofrequency ablation (RFA) treatment of atrial fibrillation can be limited
by the ability to characterize the tissue in contact. Parameters obtained by conventional
catheters, such as impedance and temperature can be insufficient in providing …
A Phase 2, Open-Label, Randomized Study of Pexa-Vec (JX-594) Administered by Intratumoral Injection in Patients with Unresectable Primary Hepatocellular …
CJ Breitbach, A Moon, J Burke, TH Hwang, DH Kirn – Gene Therapy of Solid Cancers, 2015
… Download Protocol (725 KB). Abstract. Primary liver cancer (hepatocellular carcinoma; HCC)
in patients not eligible for surgery or transplant is currently treated by locoregional therapeutic
approaches, including trans-arterial chemoembolization and radiofrequency ablation. …
[PDF] Feasibility and efficacy of helical tomotherapy in cirrhotic patients with unresectable hepatocellular carcinoma
CM Huang, MY Huang, JY Tang, SC Chen, LY Wang… – World Journal of Surgical …, 2015
… Several other treatment modalities for patients with unresectable HCC, including percutaneous
ethanol injection (PEI), radiofrequency ablation (RFA), and transcatheter arterial
chemoembolization (TACE), seem to be more effective in smaller tumors and are contraindicated …
The Wolf-Parkinson-White ECG Pattern-Assessing the Mortality Risk
E Posan – Journal of Insurance Medicine, 2015
… 32. MANAGEMENT. Radiofrequency Ablation Therapy … With pacing maneuvers, the accessory
pathway properties are defined, potential tachycardias are induced, accurate mapping (localization)
of the accessory pathway is achieved and radiofrequency ablation is employed. …
[HTML] Congenital (in growing) osteoma skull in 20-day-old neonate
PG Devi, TS Venkatachalam, YV Sharma, MP Kumar – CHRISMED Journal of …, 2015
… 6. 7. Virayavanich W, Singh R, O’Donnell RJ, Horvai AE, Goldsby RE, Link TM. Osteoid osteoma
of the femur in a 7-month-old infant treated with radiofrequency ablation. Skeletal Radiol
2010;39:1145-9. Back to cited text no. 7. 8. McHugh JB, Mukherji SK, Lucas DR. …
[PDF] Simulating and Optimizing the Response of a Sine Wave Finite state Machine with Timestamp Simulation Using Simulink
M Kalpna, MA Varma – International Journal of Research, 2015
… [5.] Dagmara M. Dołęga, Jerzy Barglik, (2012) “Computer modeling and simulation of
radiofrequency thermal ablation“, COMPEL – The international journal for computation and
mathematics in electrical and electronic engineering, Vol. 31 Iss: 4, pp.1087 – 1095 …
[PDF] Coexistence of permanent junctional reciprocating tachycardia with rheumatic valvular disease; a case sucessfully treated with radiofrequency ablation
M Aydın, A Yıldız, M Yüksel, Y İslamoğlu
Abstract A seventeen years old female had presented with palpitation. On the
electrocardiography (ECG), long RP, narrow QRS tachycardia, inverted P waves in leads
D2, D3 and aVF were noticed. On transthoracic echocardiography, rheumatic mitral …
[PDF] Macrophage Inflammatory Protein Derivative ECI301
T Radiotherapy
… inhibition by ECI301 was not attributable to radiation alone but also shown to other factors such
as the heat generated from high-frequency alter- nating current, namely radiofrequency ablation
(RFA; ref. … 5B), significant differences were ablated by the anti- HMGB1 antibody. …
[PDF] Regenerative Injection Treatment in the Spine: Review and Case Series with Platelet Rich Plasma. J Stem Cells Res
D Aufiero, H Vincent, S Sampson, M Bodor – Rev & Rep, 2015
… back or neck pain refractory to physical therapy, trigger point injections, medial branch blocks,
or radio- frequency ablation. … There is scarce evidence supporting less commonly performed
non-surgical treatments for lumbar radiculopathy including pulsed radiofrequency to the …
[HTML] Modern medicine-morcellation
SC Olmstead
… abandoned as a surgical procedure? What about noninvasive treatment options that
leave the presumed fibroid inside the body, such as uterine artery embolization,
MRI-guided focused ultrasound, and radiofrequency ablation? …
Chronic Regional Pain Syndrome (CRPS/RSD)
What outcome measures are commonly used for Complex Regional Pain Syndrome clinical trials? A systematic review of the literature
S Grieve, L Jones, N Walsh, C McCabe – European Journal of Pain, 2015
… Background and objective. Complex Regional Pain Syndrome (CRPS) is a chronic pain condition,
often triggered by trauma to a limb and characterized by sensory, motor, autonomic and trophic
changes within the affected limb. … 2.4 Classification of CRPS clinical trials. …
[PDF] MIRROR THERAPY: A REVIEW OF EVIDENCES
A Najiha, J Alagesan, VJ Rathod, P Paranthaman – Int J Physiother Res, 2015
… Three particular conditions that have been studied the most are stroke, CRPS and phantom
limb pain. … MT was used in conditions like stroke, cerebral palsy (CP), complex regional pain
syndrome (CRPS), phantom limb pain (PL) and fracture rehabilitation. …
Physical Therapy Treatment for Patients Diagnosed with Complex Regional Pain Syndrome
J Connole – 2015
… Abstract. This case study and evidence-based research analyzes the effects of physical
therapy interventions on a patient diagnosed with type 1 complex regional pain
syndrome (CRPS) to determine the most beneficial treatments. …
Hybrid short-term freeway speed prediction methods based on periodic analysis
Y Zou, X Hua, Y Zhang, Y Wang – Canadian Journal of Civil Engineering, 2015
Page 1. Hybrid short-term freeway speed prediction methods based on periodic
analysis By Yajie Zou, Ph.D. Research associate 133B More Hall, Box 352700
Department of Civil and Environmental Engineering University of …
[HTML] Japanese MD Develops Nutritional Protocols for Gardasil/Cervarix HPV Vaccine Injury
LC Botha – 2015
… subacute sclerosing panencephalitis; CRPS: Complex regional pain syndrome; POTS:
Postural orthostatic tachycardia syndrome; Anti-phospholipid antibody syndrome;
SLE: systemic lupus erythematosus; Rheumatoid arthritis; …
The social behavior of children adopted from Russian Federation: a controlled study
C Caprin, L Ballarin, L Benedan, A Castelli – Psicologia clinica dello sviluppo, 2015
… Nonostante nella ricerca si sia utilizzata la forma estesa per genitori dello strumento
(CRPS-R:L; Conners, validazione Italiana a cura di Nobile, Alberti e Zuddas, 2007), composta
da 80 item (valori di a com- presi fra 0.57 e 0.91 per i maschi e 0.58 e 0.89 per le femmine), in …
A Review of the Use of Stellate Ganglion Block in the Treatment of PTSD
E Lipov, EC Ritchie – Current Psychiatry Reports, 2015
… 14. Lipov EG, Joshi JR, et al. A unifying theory linking the prolonged efficacy of the stellate
ganglion block for the treatment of chronic regional pain syndrome (CRPS), hot flashes,
and posttraumatic stress disorder (PTSD). Med Hypotheses. …
Addiction Recovery in Services and Policy: An International Overview
A Laudet, D Best – Textbook of Addiction Treatment: International …, 2015
… model is growing in popularity nationwide: in the past decade, growing concerns about substance
use on campus and federal agencies’ focus on building a community-based continuum of care
system for youths have fueled a fivefold increase in the number of CRPs, from four …
[HTML] Related Products
R Frank
… 43. Canalith Repositioning Procedures. The recommended treatment for BPPV is a canalith
repositioning procedure (CRP). There are several CRPs described in the literature; the most
studied and used in the United States was first described by Epley in 1992. …
Central habituation and distraction alter C‐fibre‐mediated laser‐evoked potential amplitudes
P Hüllemann, YQ Shao, G Manthey, A Binder, R Baron – European Journal of Pain, 2015
Skip to Main Content. Wiley Online Library. Log in / Register. Log In E-Mail
Address Password Forgotten Password? Remember Me. …
Nuclear Medicine Imaging of Sport Injuries of the Wrist, Hand and Fingers
M Sathekge, FE Suleman, MD Velleman, R Clauss – Nuclear Medicine and …, 2015
… Abductor pollicis longus. CRPS: Chronic regional pain syndrome. … 1997 ). 24.7 Complex Regional
Pain Syndrome (Reflex Sympathetic Dystrophy, Sudeck’s Dystrophy). Complex regional pain
syndrome (CRPS) is one of the most challenging chronic pain conditions of the limbs. …
The Child with a Painful Limp
J Robb – Paediatric Orthopaedic Diagnosis, 2015
… There may be symptoms of psychological distress and further specialist evaluation may
reveal an underlying cause. Complex Regional Pain Syndrome (CRPS). Children with
CRPS type 1 affecting the lower limb often limp (Wilder et al. 1992 ). …
Complex regional pain syndrome type I. An analysis of 7 cases in children
VP Stalla, CM Olaso, VK Almada, GG Rabelino – Neurología (English Edition), 2015
Complex regional pain syndrome (CRPS) is characterised by the presence of pain accompanied
by sensory, autonomic and motor symptoms, usually preceded by a lesio. …
Vitamin C, Extremity Trauma and Surgery
N Shibuya, MR Agarwal, DC Jupiter – 2015
… 987 Abstract Complex regional pain syndrome (CRPS) is a devastating condition often seen
after extrem- ity injury and surgery. … Efficacy and safety of vitamin C used to prevent CRPS are
discussed. List of Abbreviations CRPS Complex regional pain syndrome Introduction …
Psychological Factors as Outcome Predictors for Spinal Cord Stimulation
T Bendinger, N Plunkett, D Poole, D Turnbull – Neuromodulation: Technology at the …, 2015
… SCS trials were offered for the following indications: failed back surgery syndrome (FBSS),
refractory radiculopathy or peripheral neuropathy, complex regional pain syndrome (CRPS),
and refractory angina (at the beginning of observed period—since 2008, this indication is not …
[PDF] The Role of Transitional Justice and Access to Justice in Conflict Resolution and Democratic Advancement
MF Moscati – 2015
… year mandate. The Community Reconciliation Processes (CRPs) of Timor-Leste were created
with the specific aim of dealing with disputes between … perpetrators into their communities. The
possibility of recourse to CRPs was established by the United Nations Transitional …
Complex Regional Pain Syndrome in Children: a Multidisciplinary Approach and Invasive Techniques for the Management of Nonresponders
MJ Rodriguez‐Lopez, M Fernandez‐Baena, A Barroso… – Pain Practice, 2015
… Complex regional pain syndrome (CRPS) is multifactorial condition with complex
pathogenesis characterized by spontaneous or stimulus-induced pain that is
disproportionate to the inciting event. It is also commonly accompanied …
Analgesic response to intravenous ketamine is linked to a circulating microRNA signature in female complex regional pain syndrome patients
SR Douglas, BB Shenoda, RA Qureshi, A Sacan… – The Journal of Pain, 2015
Although ketamine is beneficial in treating complex regional pain syndrome (CRPS), a subset
of patients respond poorly to therapy. We investigated treatment-ind. … Highlights. • We studied
ketamine treatment induced miRNA alterations in blood from CRPS patients. • …
Peptide signalling during the pollen tube journey and double fertilization
LJ Qu, L Li, Z Lan, T Dresselhaus – Journal of Experimental Botany, 2015
… In general, plant peptides can be categorized into two classes: secreted peptides and
non-secreted peptides. Secreted peptides can be further divided into two major classes:
cysteine-rich peptides (CRPs) and non-CRPs (NCRPs). … CRPs are significantly larger peptides. …
[HTML] Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development
J Colling, T Tohge, R De Clercq, G Brunoud, T Vernoux… – Journal of Experimental …, 2015
… Two distinct classes of secreted peptides can be distinguished in plants: small post-translationally
modified peptides such as the CLAVATA3/ENDOSPERM SURROUNDING REGION (CLE) family,
and cysteine-rich peptides (CRPs), exemplified by the EPIDERMAL …
METHODS OF MODULATING DRUG PLASMA LEVELS USING ERYTHROHYDROXYBUPROPION
H Tabuteau – US Patent 20,150,157,582, 2015
… In some embodiments, a combination of dextromethorphan and an antidepressant, such as
bupropion, may be administered to relieve complex regional pain syndrome, such as complex
regional pain syndrome type I (CRPS-I), complex regional pain syndrome type 11 (CRPS-II …
METHODS FOR THE SAFE ADMINISTRATION OF IMIDAZOLE OR IMIDAZOLIUM COMPOUNDS
H Tabuteau – US Patent 20,150,157,564, 2015
… embodiments, an osteoclast inhibitor, such as a nitrogen-containing bisphosphonate, eg
zoledronic acid, ibandronic acid or minodronic acid, may be administered to relieve complex
regional pain syndrome, such as complex regional pain syndrome type I (CRPS-I), complex …
Fibromyalgia
The Use of Polysymptomatic Distress Categories in the Evaluation of Fibromyalgia (FM) and FM Severity
F Wolfe, BT Walitt, JJ Rasker, RS Katz, W Häuser – The Journal of Rheumatology, 2015
Objective The polysymptomatic distress (PSD) scale is derived from variables used in the
2010 American College of Rheumatology (ACR) fibromyalgia (FM) criteria modified for
survey and clinical research. The scale is useful in measuring the effect of PSD over the …
Association of different levels of depressive symptoms with symptomatology, overall disease severity, and quality of life in women with fibromyalgia
A Soriano-Maldonado, K Amris, FB Ortega… – Quality of Life Research, 2015
Purpose This study examined the associations of different levels of depression with pain,
sleep quality, fatigue, functional exercise capacity, overall fibromyalgia (FM) severity, and
health-related quality of life (HRQoL) in women with FM. Methods A total of 451 women …
Fibromyalgia: Clinical Guidelines and Treatments
E Lawson, M Wallace – 2015
Major Classes of Medication for Treatment of Fibromyalgia
AM Kelly, K Mauer – Fibromyalgia: Clinical Guidelines and Treatments, 2015
Implications of proposed fibromyalgia criteria across other functional pain syndromes
N Egloff, R von Känel, V Müller, UT Egle… – Scandinavian Journal of …, 2015
Objectives: In 2010, the American College of Rheumatology (ACR) proposed new criteria for
the diagnosis of fibromyalgia (FM) in the context of objections to components of the criteria of
1990. The new criteria consider the Widespread Pain Index (WPI) and the Symptom …
Omar I. Halawa and David A. Edwards
DA Edwards – Fibromyalgia: Clinical Guidelines and Treatments, 2015
Psychophysiological Methods
RH McAllister-Williams – Encyclopedia of Psychopharmacology, 2015
… potential. Tramadol reduces pain substantially in osteoarthritis and fibromyalgia
(Bennett et al. 2003). Methadone … below). There is evidence of a mild degree of benefit
in low back pain, fibromyalgia, and headaches. Anticonvulsant …
PTSD and Fibromyalgia Syndrome: Focus on Prevalence, Mechanisms, and Impact
W Häusera, J Ablinb, B Walittc – 2015
Abstract The association between fibromyalgia syndrome (FMS) and posttraumatic stress
disorder (PTSD) is of growing interest in psychosocial research. The mechanisms by which
both disorders are interconnected are not well understood. The article presents an …
Conditioned Pain Modulation: Neurophysiological, Cognitive, And Pharmacological Aspects
RR Nir, D Yarnitsky – Topics in Pain Management, 2015
… The relevance of modulatory pain mechanisms in the clinical arena is represented through
cumulative research reporting impaired pain inhibition associated with pain disorders, particularly
fibromyalgia, irritable bowel syndrome, migraine, tension-type headache …
Ryan D. McConn and Magdalena Anitescu
RD McConn – Fibromyalgia: Clinical Guidelines and Treatments, 2015
[HTML] Another dimension of pain
TH Khan – Anaesth Pain & Intensive Care, 2015
… Pain Manag Nurs. 2013 Dec;14(4):368-78. [PubMed] doi: 10.1016/j.pmn.2011.08.001. Menzies
V, Taylor AG, Bourguignon C. Effects of guided imagery on outcomes of pain, functional status,
and self-efficacy in persons diagnosed with fibromyalgia. J Altern Complement Med. …
[HTML] Pattern of irritable bowel syndrome and its impact on quality of life: A tertiary hospital based study from Kolkata on newly diagnosed patients of irritable bowel …
U Sinharoy, K Sinharoy, P Mukhopadhyay… – CHRISMED Journal of …, 2015
… [6],[7],[8],[9] IBS can coexist with other functional disorders, most notably fibromyalgia, chronic
fatigue syndrome … 10. 11. Aaron LA, Burke MM, Buchwald D. Overlapping conditions among
patients with chronic fatigue syndrome, fibromyalgia, and temporomandibular disorder. …
[PDF] Disability Status, Disability Type, and Training as Predictors of Job Placement
J Stahl – 2015
… Deafness Hearing, Communicating Deafness Neurological Memory, Speaking TBI, Multiple
Sclerosis, Fibromyalgia Developmental Reading, Writing, Speaking Autism, Williams Syndrome …
Mental Neurological Memory, Speaking TBI, Multiple Sclerosis, Fibromyalgia …
[HTML] Pilates for Fibromyalgia
DPT Tom Lavosky, C MDT
By Gabrielle Shirer As originally seen in the Fall 2006 edition of the Pilates Coreterly
According to the National Fibromyalgia Association, Fibromyalgia Syndrome (FMS) is an
increasingly recognized chronic pain illness characterized by widespread …
New study by guidelines author dismisses risk of chronic Lyme disease
D Cameron
… In addition, these patients were not more prone to developing fibromyalgia and/or chronic fatigue,
according to two additional papers by Dr. Wormser. … [1]. And previous studies report there’s a
high risk of developing fibromyalgia after having Lyme disease. …
[HTML] Evolution of Skin Temperature after the Application of Compressive Forces on Tendon, Muscle and Myofascial Trigger Point
MF Magalhães, AV Dibai-Filho, EC de Oliveira Guirro… – PLOS ONE, 2015
… of musculoskeletal, tendon or nervous injuries in the upper limb, history of fracture in the upper
limb, use of painkillers, anti-inflammatory drugs or muscle relaxants during the previous week,
presence of systemic or neuromuscular diseases, and medical diagnosis of fibromyalgia …
[HTML] Rejuvenate With Stem Cells
R Schilling – 2015
… literature. This combination (laser activated, intravenous mesenchymal injection) has
the potential for being useful for a multitude of chronic illnesses like fibromyalgia,
MS, generalized arthritis, just to mention a few. Mesenchymal …
[PDF] Regenerative Injection Treatment in the Spine: Review and Case Series with Platelet Rich Plasma. J Stem Cells Res
D Aufiero, H Vincent, S Sampson, M Bodor – Rev & Rep, 2015
… Positive results for Prolotherapy have been published for a variety of conditions including lateral
epicondylosis [21], osteoarthritis [22], sacroiliac joint pain [23], chondromalacia patellae [24],
fibromyalgia [25], chronic groin pain [26] and Osgood-Schlatter disease [27]. …
[PDF] APPROVAL SHEET
M Holman – 2015
… Page 14. Effect of US and Graston on Muscle Contraction 11 plantar fasciitis,
patellofemoral disorders, fibromyalgia, scar tissue, and trigger finger. 13 The Graston
Technique allows for controlled application of friction massage to the …
[HTML] Blueg rass Doctors of Physical Therapy, PLLC Physical Therapy Care Provider in the Louisville, Kentucky We provide EXPERT CARE for YOUR Health!
N Patient, C Forms
… There are many symptoms that can lead the person with fibromyalgia syndrome (FMS)
and/or chronic myofascial pain (CMP) to your office. … Research indicates that fibromyalgia
may increase the risk of cardiovascular disease (Curtis, O’Keefe Jr 2002). …
