by admin | Dec 7, 2015 | Uncategorized
People born with a rare genetic mutation are unable to feel pain, but previous attempts to recreate this effect with drugs have had surprisingly little success. Using mice modified to carry the same mutation, UCL researchers funded by the MRC and Wellcome Trust have now discovered the recipe for painlessness.
‘Channels’ that allow messages to pass along nerve cell membranes are vital for electrical signalling in the nervous system. In 2006, it was shown that sodium channel Nav1.7 is particularly important for signalling in pain pathways and people born with non-functioning Nav1.7 do not feel pain. Drugs that block Nav1.7 have since been developed but they had disappointingly weak effects.
The new study, published in Nature Communications, reveals that mice and people who lack Nav1.7 also produce higher than normal levels of natural opioid peptides.
To examine if opioids were important for painlessness, the researchers gave naloxone, an opioid blocker, to mice lacking Nav1.7 and found that they became able to feel pain. They then gave naloxone to a 39-year-old woman with the rare mutation and she felt pain for the first time in her life.
“After a decade of rather disappointing drug trials, we now have confirmation that Nav1.7 really is a key element in human pain,” says senior author Professor John Wood (UCL Medicine). “The secret ingredient turned out to be good old-fashioned opioid peptides, and we have now filed a patent for combining low dose opioids with Nav1.7 blockers. This should replicate the painlessness experienced by people with rare mutations, and we have already successfully tested this approach in unmodified mice.”
Broad-spectrum sodium channel blockers are used as local anaesthetics, but they are not suitable for long-term pain management as they cause complete numbness and can have serious side-effects over time. By contrast, people born without working Nav1.7 still feel non-painful touch normally and the only known side-effect is the inability to smell.
Opioid painkillers such as morphine are highly effective at reducing pain, but long-term use can lead to dependence and tolerance. As the body becomes used to the drug it becomes less effective so higher doses are needed for the same effect, side effects become more severe, and eventually it stops working altogether.
“Used in combination with Nav1.7 blockers, the dose of opioid needed to prevent pain is very low,” explains Professor Wood. “People with non-functioning Nav1.7 produce low levels of opioids throughout their lives without developing tolerance or experiencing unpleasant side-effects. We hope to see our approach tested in human trials by 2017 and we can then start looking into drug combinations to help the millions of chronic pain patients around the world.”
The findings were made possible by the use of ‘transgenic’ mice, meaning they were modified to carry genetic material from another organism — in this case, the mutation that prevents humans from feeling pain. Precise physiological experiments showed that the nervous systems of the transgenic mice contained around twice the levels of naturally-produced opioids as unmodified mice from the same litter.
“Our results reaffirm the clinical relevance of transgenic mouse models for human diseases,” says Professor Wood. “Studying the mice showed us what was going on in the nervous system that led to painlessness and our findings were directly translatable to humans, as confirmed by the painless patient. Without the work in transgenic mice, none of this would have been possible and we still wouldn’t know how to replicate the effects to help people suffering from chronic pain.”
Story Source:
University College London. “Genetically modified mice reveal the secret to a painless life: Researchers have discovered the pharmaceutical recipe for painlessness.” ScienceDaily. ScienceDaily, 4 December 2015. <www.sciencedaily.com/releases/2015/12/151204090034.htm>
Journal Reference:
- Michael S. Minett, Vanessa Pereira, Shafaq Sikandar, Ayako Matsuyama, Stéphane Lolignier, Alexandros H. Kanellopoulos, Flavia Mancini, Gian D. Iannetti, Yury D. Bogdanov, Sonia Santana-Varela, Queensta Millet, Giorgios Baskozos, Raymond MacAllister, James J. Cox, Jing Zhao, John N. Wood. Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7. Nature Communications, 2015; 6: 8967 DOI: 10.1038/ncomms9967
by admin | Nov 5, 2015 | Uncategorized
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Innate immunity of surfactant proteins A and D in urinary tract infection with uropathogenic Escherichia coli
F Hu, G Ding, Z Zhang, LA Gatto, S Hawgood… – Innate Immunity, 2015
… UTI was induced as previously described, 30 with some modifications. In brief, mice were
anesthetized by ip injection with ketamine/xylazine (90 mg/kg ketamine and 10 mg/kg xylazine),
and were gently massaged and pushed down on the bladder to expel urine. …
[PDF] Comparison of propofol and ketofol in minor gynecologic interventions
Y Işık, Z Kurdoğlu, U Göktaş, İ Katı, D Sözen – J Clin Exp Invest www. jceionline. org …, 2015
… Propofol is administered as an infusion instead of in repeated doses, which prevents
dose-dependent respiratory and cardiovascular system depression and pro- vides controlled
sedation [1]. Ketamine is preferred for premedication, anesthesia induction and main- tenance …
Anesthesia Complications of Pediatric Radiotherapy
V Verma, AB Beethe, M LeRiger, RR Kulkarni, M Zhang… – Practical Radiation …, 2015
… While agents such as ketamine (complication rates approaching 23-24%) have been used
in the past, other agents such as propofol and volatile anesthetics have lower complication
rates due to improved drug side effect profiles (0.01-3.5%). …
[HTML] Stress activates the nucleus incertus and modulates plasticity in the hippocampo-medial prefrontal cortical pathway
R Rajkumar, Y Wu, U Farooq, WH Tan, GS Dawe – Brain Research Bulletin, 2015
… Ketamine (Parnell Manufacturing Pty Ltd; Alexandria, NSW, Australia), xylazine (Ilium Xylazil,
Troy Laboratories Pty Ltd; Glendenning, NSW, Australia), enrofloxacin (Baytril 5%, Bayer Health
Care; Seoul, Korea) and carprofen (Carprieve, Norbrook Laboratories (GB), Ltd …
The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect
K Pytka, A Dziubina, K Młyniec, A Dziedziczak… – Pharmacological Reports, 2015
Depression is one of the most common mental disorders and social issue worldwide. Although
there are many antidepressants available, the effectiveness of the th.
[HTML] Communicating with mismatch and tension: treatment provision experiences of primary care doctors treating patients with overactive bladder in Hong Kong
JY Siu – BMC Family Practice, 2015
… [P6]. During the study period, the symptoms of OAB, particularly urinary frequency and
urinary incontinence, were identified by government antisubstance abuse public service
announcements as signs and consequences of ketamine abuse. …
Hydrogen sulfide (H 2 S) attenuates uranium-induced acute nephrotoxicity through oxidative stress and inflammatory response via Nrf2-NF-κB pathways
J Zheng, T Zhao, Y Yuan, N Hu, X Tang – Chemico-Biological Interactions, 2015
… sacrificed. After urine collection, rats were anesthetized by an ip injection of
ketamine-xylazine (50 mg/kg ketamine and 5 mg/kg xylazine), and blood samples
were obtained directly from the heart ventricle in anesthetized animals. …
[PDF] General discussion and future perspectives
SA Bouwense, M de Vries, LT Schreuder, SS Olesen… – PDF hosted at the Radboud …, 2015
… even if technically successful. If central nervous system pain processing is altered,
specific treatment targeting these changes should be instituted (eg gabapentinoids,
ketamine or tricyclic antidepressants). Suitable tools are …
Propofol target-controlled infusion for sedated gastrointestinal endoscopy: A comparison of propofol alone versus propofol–fentanyl–midazolam
CD Hsu, JM Huang, YP Chuang, HY Wei, YC Su… – The Kaohsiung Journal of …, 2015
… The currently used regimens include propofol, benzodiazepines (such as midazolam and
diazepam), opioids (such as fentanyl and remifentanil), ketamine, and de-dexmedetomidine
[3], [4], [5] and [6]. Among them propofol has become popular in developed countries, because …
[PDF] A Critical Case of Closed Cervix Pyometra in a Bitch
JK Agrawal, A Saxena, P Kumar, A Patel – International Journal of Livestock Research, 2015
… General anethesia was induced and maintained by a combination of ketamine hydrochloride @
5mg/kg and Xylazine @ 0.2mg/kg body weight intravenously following premedication with atropine
sulphate @ 0.04mg/kg body weight. Laparotomy was performed …
Radiofrequency Ablation (RFA)
Treatment of Neuroendocrine Liver Metastases
HA Farley, RF Pommier – Surgical Oncology Clinics of North America, 2015
… Treatment options: radiofrequency ablation. RFA is another technique used to treat
neuroendocrine metastases of the liver, but it has limitations. One can ablate a limited number
of lesions (generally up to 5), of limited size (generally <5 cm in diameter), provided they are …
[PDF] Ablative Techniques in Advanced Pancreatic Cancer: Do They Affect The Quality of Life?–Review
D Dimitrov, H Feradova, D Gincheva, L Dall’Olio – JOP. J Pancreas (Online), 2015
… Such ablative therapies are high-intensity focused ultrasound (HIFU), radiofrequency
ablation (RFA), irreversible electroporation (IRE), iodine-125, iodine-125–cryosurgery,
photodynamic therapy (PDT) and microwave ablation [8]. …
Minimally Invasive Techniques for Resection of Pancreatic Neuroendocrine Tumors
GGF Ranvier, D Shouhed, WB Inabnet – Surgical Oncology Clinics of North America, 2015
Please note that Internet Explorer version 8.x will not be supported as of January 1,
2016. Please refer to this blog post for more information. Close. …
[HTML] Colorectal Liver Metastasis, Primary Gallbladder Carcinoma and Myelofibrosis Present Simultaneously in a Liver Resection Specimen
SA Gray, MH Raber, E Provoost, GJ Toes, JM Klaase – Case Reports in …, 2015
… An elective operation was scheduled, and the surgeon performed a wedge resection of segments
5 and 7 of the liver, and a radiofrequency ablation was used to treat a lesion in segment 3.
Although the suspicion of gallbladder carcinoma at the time of surgery was low, the …
Nontraumatic Cervical Spine for Primary Care Providers
CR Hemmer – The Journal for Nurse Practitioners, 2015
… physical therapy, a home traction unit, transcutaneous electrical nerve stimulation, epidural steroid
injections, selective nerve root blocks (transforaminal injections), botulinum toxin type A injections,
medication management, radiofrequency ablation, and surgical correction. …
Surgical Management of Adrenocortical Carcinoma: An Evidence-Based Approach
J Datta, RE Roses – Surgical Oncology Clinics of North America, 2015
Please note that Internet Explorer version 8.x will not be supported as of January 1,
2016. Please refer to this blog post for more information. Close. …
SYSTEM AND METHOD FOR RECONSTRUCTING CARDIAC SIGNALS ASSOCIATED WITH A COMPLEX RHYTHM DISORDER
S Narayan, R Sehra – US Patent 20,150,289,807, 2015
… For instance, ablation success for atrial tachycardias (a ‘simple’ disorder) may be as low as 70%. …
Thus, ablating the cause of a heart rhythm disorder can be challenging, and even experienced
practitioners may require hours to ablate certain ‘simple’ rhythm disorders …
[HTML] RADIONUCLIDE IMAGING AND THERAPY OF NEUROENDOCRINE TUMOURS
S Navalkissoor, G Gnanasegaran – Journal of Cancer & Allied Specialties, 2015
… These include surgical debulking, chemotherapy, molecular targeted therapies (eg sunitinib
and everolimus), interferon, somatostatin analogues, local therapies (eg radiofrequency ablation
or embolisation) and peptide receptor radionuclide therapy (PRRT). …
[PDF] Successful Radiofrequency Pulmonary Vein Isolation In A Patient With Pneumonectomy
F Kilicaslan, EE Gul, C Erol
… Circumferential radiofrequency ablation of ipsilateral PVs was done (30-35 W, 17
mL/min) with irrigated catheter (Sprinklr, Medtronic, Minneapolis, USA) and both,
entrance and exit blocks were achieved after the ablation. Interestingly …
[PDF] Ablation Is A Treatment Option Without Permanent Pacemaker Implantation For Bradycardia With Persistent Atrial Fibrillation
W Yamada, K Tanimoto, M Yamada, K Inagawa…
… Page 5. Rotational Atriography Of Left Atrium – A Imaging Technique Used To Support Left Atrial
Radiofrequency Ablation: A Comparison Of Anatomical Data Of Left Atrium F. Lehar, Z. Starek,
J. Jez, J. Wolf, T. Kulik, A. Zbankova, M. Novak Department of Cardiology, ICRC/St. …
Complex Regional Pain Syndrome (CRPS/RSD)
[PDF] Do insiders trade on mispricing after earnings announcements?
JP Fidrmuc, J Novák, H Contreras – 2015
Page 1. Do insiders trade on mispricing after earnings announcements? Jana P.
Fidrmuc∗ Warwick Business School Jirı Novák† Charles University Harold Contreras‡
Warwick Business School October 21, 2015 Abstract This …
[PDF] A predictive framework for evaluating models of semantic organization in free recall
NW Morton, SM Polyn – Journal of Memory and Language, 2015
Research in free recall has demonstrated that semantic associations reliably influence the
organization of search through episodic memory. However, the specific.
6-, 7-, OR 8-SUBSTITUTED QUINAZOLINONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME
GW Muller, H Man – US Patent 20,150,291,555, 2015
… Examples of diseases or disorders include, but are not limited to, cancer, disorders associated
with angiogenesis, pain including, but not limited to, Complex Regional Pain Syndrome (“CRPS”),
Macular Degeneration (“MD”) and related syndromes, skin diseases, pulmonary …
[PDF] Psychological distress and stressful life events in pediatric complex regional pain syndrome
MD Hannah Brehmer, MD Boris Zernikow
… Complex regional pain syndrome (CRPS) is increasingly recog- nized as a serious pain
disorder in children and adolescents. … Specifically, it is not known which factors precipitate
CRPS and which result from the ongoing painful disease. …
[PDF] In the High Court of New Zealand Wellington Registry
L SEALES, SAOFL SEALES
… Pain News 11 (1) 2013 pages 30-33. Safarfashandi Z, Munglani R, Safarfashandi L, Sadheura
J, Jenner C “The incidence of complex regional pain syndrome (CRPS) post trauma and the
possible role of tight plaster of Paris in the aetiology of CRPS“. …
[PDF] Assessment Report
CO Onyango, Y Suwa, Y Pinto
… directory ….. 18 – Table 5: List of ASTI publications in Phase II 3 ….. 20 Table 6: Summary of
ex-post impact assessments by CGIAR Centres, CRPs and SPIA ….. 29 …
[PDF] Hereditary Immunity against Infectious Diseases
IA Shabarov, ZI Urmancheeva, SN Rumyantsev…
Page 1. 1 Innovative Immunology | www.austinpublishinggroup.com/ebooks Copyright
© Rumyantsev SN.This book chapter is open access distributed under the Creative
Commons Attribu- tion 4.0 International License, which …
Encyclopedia of Exploration Geophysics
M this Chapter
Page 1. U1-1 Abstract To produce a reliable image of the subsur- face, we must use
a depth-migration scheme that requires a detailed model of the parameter fields for
use by migration. Obtaining reliable values of all parameters …
Fibromyalgia
[PDF] Does “Multiple Labeling” Benefit or Harm in Fibromyalgia Patients
E Trallero, C Alegre – Fibrom open, 2015
A systematic review showed that there is no evidence an accurate diagnosis of fibromyalgia
per se could worsen prognosis in patients with this condition [1]. Indeed, it could be useful to
reduce healthcare utilization by patients. Nevertheless, social and individual long-term …
[PDF] Comparison between Depression Levels of Women with Knee Osteoarthritis, Rheumatoid Arthritis, and Fibromyalgia Syndrome: A Controlled Study
D Karşılaştırılması, BK Çalışma – 2015
DOI: 10.5152/tftrd.2015.87894 Turk J Phys Med Rehab 2015;61:197-202 Türk Fiz Tıp Rehab
Derg 2015;61:197-202 … Comparison between Depression Levels of Women with … Diz
Osteoartrit, Romatoid Artrit ve Fibromiyalji Sendromlu Kadınlarda Depresyon …
NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR …
CH Lee, K Lee – US Patent 20,150,291,509, 2015
… group consisting of dermatitis, allergy, atopy, conjunctivitis, periodontitis, rhinitis, tympanitis,
pharyngolaryngitis, tonsillitis, pneumonia, gastric ulcer, gastritis, Crohn’s disease, colitis, irritable
colitis, hemorrhoids, gout, ankylosing spondylitis, lupus, fibromyalgia, psoriasis, arthritis …
[PDF] Recent advances in massage therapy–a review
SL LIU, W Qi, H Li, YF WANG, XF YANG, ZM LI, Q Lu… – Eur Rev Med Pharmacol Sci, 2015
… in animal models. In a randomized trial conducted by Ekici et al13, application of
MLD to women with fibromyalgia resulted in improvements regarding pain, health
status, and health-related quality of life. Lancaster and Crow14 …
Immediate Effect of Basic Body Awareness Therapy on Heart Rate Variability
AM Mantovani, CEPT Fregonesi, RMR Lorençoni… – … Therapies in Clinical …, 2015
To determine the immediate effect of a Basic Body Awareness Therapy (BAT) session on
measures of heart rate variability (HRV) in healthy young people.13 healthy.
[PDF] Radial shock wave therapy in the treatment of lateral epicondylitis
JD Rompe, J Decking, C Schoellner, C Theis…
… P009-e Gait analysis: An objective measurement for subgrouping fibromyalgia patients B. Auvinet
a,*, D. Chaleil b, J. Cabane c, A. Dumolard d, P. Hatron e, R. Juvin d, M. Lanteri-minet f, Y. Mainguy
g, L. Negre-pages h, F. Pillard i, D. Riviere i, Y. Maugars j a Clinique, 8, rue des …
2-OXO-2, 3-DIHYDRO-INDOLES FOR THE TREATMENT OF CNS DISORDERS
D Brunner, J Malberg, BG Shankar, S Kolczewski… – US Patent 20,150,284,386, 2015
… Fibromyalgia, which is a syndrome characterized by chronic generalized pain associated with
different somatic symptoms, such as sleep disturbances, fatigue, stiffness, balance problems,
hypersensitivity to physical and psychological environmental stimuli, depression and …
HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF
JE Campbell, P Jones – US Patent 20,150,291,626, 2015
… affective disorder, seasonal affective disorder, obsessive-compulsive disorder, attention deficit
disorder, attention deficit hyperactivity disorder, vertigo, pain, neuropathic pain, sensitization
accompanying neuropathic pain, inflammatory pain, fibromyalgia, migraine, cognitive …
[PDF] How is Qigong Conducive to Women’s Health
FK Cheng – Int J Complement Alt Med, 2015
… Likewise, Tai Chi is beneficial for treating fibromyalgia, achieving better symptomatology,
aerobic capacity, dynamic balance, body strength, and walking distance [112]. Psychological
health: Studies inform the effects of Baduanjin on mental well-being. …
[HTML] Recommendations to the primary care practitioners and the patients for managing pelvic pain, especially in painful bladder syndrome for early and better prognosis
KJ Chung, ANY Han, KH Kim – Journal of Exercise Rehabilitation, 2015
… Scholar]. Nickel JC., Tripp DA., Pontari M., Moldwin R., Mayer R., Carr LK., Doggweiler R., Yang
CC., Mishra N., Nordling J. Interstitial cystitis/painful bladder syndrome and associated medical
conditions with an emphasis on irritable bowel syndrome, fibromyalgia and chronic …
by admin | Sep 23, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
[HTML] Upper urinary tract damage caused by ketamine snorting—A report of nine cases
HY Lee, YC Hsu, CY Hsu, ECL Chou, CC Li, YS Juan… – Urological Science, 2015
Objective The toxicity of ketamine to genitourinary system not only involved in lower urinary
tract, which include urinary frequency, urgency, suprapubic pain, dysuria and hematuria, but
also upper urinary tracts. However, the reports of ketmaine-induced upper urinary tract …
Inconsistency of allometric scaling for dissociative anesthesia of wild felids
AB Carregaro, GC Freitas, SP Bisetto, NV Xavier… – Veterinary anaesthesia and …, 2015
… Keywords: allometric scaling; dissociative anesthesia; ketamine; metabolic rate; xylazine.
Abstract. … Objective. To evaluate allometric scaling for ketamine–xylazine (KX) anesthesia
in wild felids using domestic cats for reference. Study design. …
[PDF] The ERα-PI3K Cascade in Pro-opiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice
L Zhu, P Xu, X Cao, Y Yang, AO Hinton Jr, Y Xia… – Endocrinology, 2015
… Hypothalamic ER -p85 interaction and phosphorylation of AKT in response to icv PPT
Female C57Bl6 mice (12 weeks) were anesthetized with ip injections of
ketamine/xylazine cocktail (100 mg/kg ketamine and 10 mg/kg xylazine). …
[HTML] Effects of leptin on sympathetic nerve activity in conscious mice
DA Morgan, F Despas, K Rahmouni – Physiological Reports, 2015
… Here, we examined the sympathetic responses evoked by leptin in conscious mice. Mice
were instrumented, under ketamine/xylazine anesthesia, with renal or lumbar SNA
recordings using a thin (40 gauge) bipolar platinum–iridium wire. …
[PDF] Treatment of Pain with Antidepressants
B Kerr, C Benson, K Mifflin, SJB Jesudasan, S Dursun… – Klinik Psikofarmakoloji …, 2015
… depression43-45. There has been a great deal of interest in the NMDA receptor antagonist
ketamine and its rapid acting antidepressant action when infused46,47, and it is interesting that
this drug has also been used in treatment of therapy-resistant chronic pain48. …
Use of LigaSure on bile duct in rats. An experimental study.
A Marte, L Pintozzi – Minerva pediatrica, 2015
… in rats. MATERIALS AND METHODS: Thirty Wistar rats weighing 70 to 120gr were
employed for this study. The animals were all anaesthetized with intraperitoneal
Ketamine and then divided into three groups. The first group …
[HTML] Maxcal-C (a polyherbal formulation) prevents ovariectomy-induced osteoporosis in rats
RA Maheshwari, F Dhakwala, R Balaraman, AK Seth… – Indian Journal of …, 2015
… Standard drug Calcium Sandoz (cholecalciferol), ketamine hydrochloride, diazepam, povidone,
and ampicillin were purchased from commercial market. … The rats were anesthetized with injection
of ketamine hydrochloride (40 mg/kg. ip) and diazepam (5 mg/kg, im). …
Positive reinforcing effect of oxytocin microinjection in the rat central nucleus of amygdala
K László, A Kovács, O Zagoracz, T Ollmann, L Péczely… – Behavioural Brain Research, 2015
… 00 h. 2.2. Surgery. Rats were anesthetized ip by ketamine supplemented with
diazepam (Calypsol and Seduxen, Richter Gedeon, Hungary, ketamine: 80
mg/kg body weight, diazepam: 20 mg/kg body weight). Animals were …
Minocycline Attenuates Depressive‐like Behaviour Induced by Rat Model of Testicular Torsion: Involvement of Nitric Oxide Pathway
SSS Saravi, SE Mousavi, SSS Saravi, AR Dehpour – Basic & Clinical Pharmacology & …, 2015
… Testicular Torsion/Detorsion Animals were anaesthetized with intraperitoneal injection of ketamine
HCl (50 mg/kg) and chlorpromazine (25 mg/kg). … 30 days. Testosterone assay At day 30, the rats
were anaesthetized with intraperitoneal injection of ketamine HCl (50 mg/kg) …
Spinal Reflexes and Windup In Vitro: Effects of Analgesics and Anesthetics
I Rivera‐Arconada, C Roza, JA Lopez‐Garcia – CNS Neuroscience & Therapeutics, 2015
… Spinal cord mechanisms may contribute toward analgesia and akinesia. Ketamine.
The general anesthetic ketamine is a noncompetitive blocker of NMDA receptors
that also shows activity on several ionic channels. As expected …
Augmentation Therapy With Serial Intravenous Ketamine Over 18 Months in a Patient With Treatment Resistant Depression.
S Hassamal, M Spivey, AK Pandurangi – Clinical Neuropharmacology, 2015
Abstract Major depressive disorder is a severe illness that affects 3% to 7% of adults
annually in the United States. About 30% of these individuals are refractory to multiple
treatment trials. Recent reports have found a significant and almost immediate …
Ketamine Increases Permeability and Alters Epithelial Phenotype of Renal Distal Tubular Cells Via a GSK‐3β‐Dependent Mechanism
HY Shyu, CJ Ko, YC Luo, HY Lin, SR Wu, SW Lan… – Journal of Cellular …, 2015
Abstract Ketamine, a dissociative anesthetic, is misused and abused worldwide as an illegal
recreational drug. In addition to its neuropathic toxicity, ketamine abuse has numerous
effects, including renal failure; however, the underlying mechanism is poorly understood. …
More effective induction of anesthesia using midazolam-butorphanol-ketamine-sevoflurane compared with ketamine-sevoflurane in the common marmoset monkey ( …
H ISHIBASHI – Journal of Veterinary Medical Science, 2015
The common marmoset has been increasingly used for research in the biomedical field;
however, there is little information available regarding effective methods of anesthesia in this
species. This study retrospectively analyzed 2 regimens of anesthesia induction: …
[HTML] Comparison of Ketamine–Medetomidine-butorphanol and Ketamine–dexmedetomidine-butorphanol Anesthesia in Rats
R Costea, D Lastofka, M Mehedinţu – Agriculture and Agricultural Science Procedia, 2015
Abstract We evaluated the effect of ketamine-dexmedetomidine-butorphanol (K, 80 mg/kg;
D, 0.25 mg/kg, B, 0.5 mg/kg) and ketamine-medetomidine-butorphanol (K, 80 mg/kg; M, 0.25
mg/kg, B, 0.5 mg/kg) administered intraperitoneally, during anesthesia and immediate …
Pulmonary immunostimulation with MALP-2 in influenza virus-infected mice increased survival after pneumococcal superinfection
K Reppe, P Radünzel, K Dietert, T Tschernig, T Wolff… – Infection and Immunity, 2015
… Five days after IAV infection, 114 the mice were anesthetized intraperitoneally
(ip) with ketamine (80 mg/kg, Ketavet®, Pfizer, 115 … re-suspended in sterile PBS.
Mice were anesthetized ip with ketamine and xylazine and 123 …
Atorvastatin along with imipenem attenuates acute lung injury in sepsis through decrease in inflammatory mediators and bacterial load
S Choudhury, K Kannan, BS Maruti, MP Addison… – European Journal of …, 2015
… ad libitum. The animals were anesthetized by injection of xylazine (10 µg/g body
weight, intraperitoneally) and ketamine (80 µg/g body weight, intraperitoneally) and
a 2-cm ventral midline incision was performed. The cecum …
[HTML] Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase
YJ Lai, GJ Chang, YH Yeh, JHS Pang, CC Huang… – PLOS ONE, 2015
… All the surgery was performed under ketamine and xylazine ip anesthesia, and all efforts were
made to minimize suffering. Housing and maintenance was provided by Chang Gung University,
All animals were fed a standard chow diet with free access to water. …
[HTML] Serotonin 5-HT 7 receptor agonist, LP-211, exacerbates Na+, K+-ATPase/Mg 2+-ATPase imbalances in spinal cord-injured male rats
A Norouzi-Javidan, J Javanbakht, F Barati, N Fakhraei… – Diagnostic Pathology, 2015
… Animals were anesthetized by intraperitoneal injection of a mixture of ketamine hydrochloride
(75 mg/kg) and xylazine hydrochloride (5 mg/kg). … All animals were anesthetized (ketamine
hydrochloride 10 % + xylazine 2 %, in 80 and 5 mg/kg doses, respectively). …
[HTML] Interleukin-17A and Neutrophils in a Murine Model of Bird-Related Hypersensitivity Pneumonitis
M Ishizuka, Y Miyazaki, M Masuo, K Suhara, T Tateishi… – PLOS ONE, 2015
… They were then placed under light anesthesia with 100 mg/kg ketamine and 10 mg/kg xylazine,
and 5 μg of PDE in 25 μl of 0.9% saline was sprayed into each mouse’s trachea using an
intratracheal MycroSprayer® aerosolizer (Penn-century, Wyndmoor, PA, USA). …
Pertussis toxin reduces calcium influx to protect ischemic stroke in a middle cerebral artery occlusion model
Z Tang, S Li, P Han, J Yin, Y Gan, Q Liu, J Wang… – Journal of Neurochemistry, 2015
… blinded to the randomization. Permanent Middle Cerebral Artery Occlusion (pMCAO) Mice were
under Ketamine/Xylazine anesthesia (80 mg/kg Ketamine and 10mg/kg Xylazine, injected ip).
Standard aseptic surgical procedures were used throughout the procedure. The …
Radiofrequency Ablation (RFA)
Effectiveness and safety of computed tomography-guided radiofrequency ablation of renal cancer: a 14-year single institution experience in 203 patients
JD Iannuccilli, DE Dupuy, MD Beland, JT Machan… – European Radiology, 2015
Objectives To define effectiveness and safety of CT-guided radiofrequency ablation (RFA) of
renal tumours and prognostic indicators for treatment success. Methods Patients with a
single treatment of a solitary, biopsy-proven renal tumour with intent to cure over a 14-year …
Outcomes associated with ablation compared to combined ablation and transilluminated powered phlebectomy in the treatment of venous varicosities.
AT Obi, BN Reames, TJ Rook, SO Mouch, A Zarinsefat… – Phlebology/Venous Forum …, 2015
… RESULT: Venous clinical severity scores improved more with radiofrequency ablation +
transilluminated powered phlebectomy as compared to radiofrequency ablation alone
(3.8 ± 3.4 vs. 3.2 ± 3.1, p = 0.018). … radiofrequency ablation alone. …
Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations
S Mercadante, P Klepstad, G Paula Kurita, P Sjøgren… – Acta Oncologica, 2015
… Radiofrequency ablation (RFA). … RFA resulted more effective than radiotherapy and surgical
stabilization [99. Di Francesco A, Flamini S, Zugaro L, Zoccali C. Preoperative
radiofrequency ablation in painful osteolytic long bone metastases. …
[HTML] Efficiency and safety of radiofrequency-assisted hepatectomy for hepatocellular carcinoma with cirrhosis: A single-center retrospective cohort study
F Zhang, J Yan, XB Feng, F Xia, XW Li, KS Ma, P Bie – World J Gastroenterol, 2015
… These procedures include liver transplantation, resection, and radiofrequency ablation[ 5 ]. Liver
transplantation may be the best treatment option for cirrhotic patients with HCC because it involves
the simultaneous removal of both the cirrhotic liver and HCC[ 6 ]. However, the …
Ethanol ablation in post-biopsy liver hemorrhage following two failed Embolizations
MC Pope, DH Ballard, AL Sticker, C Ahuja… – Clinical Imaging, 2015
… C. The feeding vessels were identified and ablated with an additional 10 mL ethanol injection. …
to ultrasound-guided percutaneous ethanol injection for achieving hemostasis include techniques
such as cryoablation, radiofrequency (RF)-ablation, and cyanoacrylate glue …
[PDF] Catheter Ablation of Fascicular Ventricular Tachycardia: Long Term Clinical Outcomes and Mechanisms of Recurrence
Y Liu, Z Fang, B Yang, P Kojodjojo, H Chen, W Ju… – Circulation: Arrhythmia and …, 2015
… ablated. … Arrhythmia recurrences after an initially successful ablation were caused by recurrent
FVT involving the … Key words: ventricular tachycardia, radiofrequency, idiopathic left ventricular
tachycardia, fascicular ventricular tachycardia, outcomes, radiofrequency ablation …
Liver metastases from adenocarcinomas of unknown primary site: management and prognosis in 68 consecutive patients
E Algin, A Ozet, O Gumusay, G Yilmaz, S Buyukberber… – Wiener klinische …, 2015
… shown in Fig. 1. Among 39 patients who were managed with chemo- therapy, 12
patients received additional locoregional therapies including radiofrequency ablation
or transar- terial chemoembolization. Median OS was 9.4 …
[HTML] The Prognostic Value of Platelet Count in Patients With Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Q Pang, K Qu, JY Zhang, SD Song, SS Liu, MH Tai… – Medicine, 2015
… Abbreviations: HBV = hepatitis B virus, HCC = hepatocellular carcinoma, HCV = hepatitis C virus,
HR = hazard ratio, MPV = mean platelet volume, OS = overall survival, PLT = platelet count, RFA =
radiofrequency ablation, RFS = recurrence-free survival, TACE = transcatheter …
Safety and Feasibility of Open Chest Epicardial Mapping and Ablation of Ventricular Tachycardia During the Period of Left Ventricular Assist Device Implantation
M Patel, F Rojas, FR Shabari, L Simpson, W Cohn… – Journal of Cardiovascular …, 2015
… Endocardial and epicardial radiofrequency ablation of ventricular tachycardia associated with
dilated cardiomyopathy: The importance of low-voltage scars. … Comparison of epicardial
cryoablation and irrigated radiofrequency ablation in a swine infarct model. …
Contact Force Variability during Catheter Ablation of Atrial Fibrillation: The Role of Atrial Rhythm and Ventricular Contractions: Co-Force AF Study
A Sarkozy, D Shah, J Saenen, J Sieira, T Phlips… – Circulation: Arrhythmia and …, 2015
… 3 Background Lesion formation by using radiofrequency (RF) current depends on the power
delivered, duration of energy application, temperature, tip size, and tip orientation. … given RF power1.
Irrigated tip ablation catheters capable of real-time CF measurement have …
[HTML] Pulmonary vein isolation using the visually guided laser balloon: a prospective, multicenter, and randomized comparison to standard radiofrequency ablation
SR Dukkipati, F Cuoco, I Kutinsky, A Aryana… – Journal of the American …, 2015
Background Balloon catheters have been designed to facilitate pulmonary vein (PV)
isolation in patients with paroxysmal atrial fibrillation (AF). The visually guided laser balloon
(VGLB) employs laser energy to ablate tissue under direct visual guidance. Objectives …
Optimal Temperature for Radiofrequency Ablation of Lumbar Medial Branches for Treatment of Facet‐Mediated Back Pain
S Costandi, M Garcia‐Jacques, T Dews, M Kot, K Wong… – Pain Practice, 2015
Background Radiofrequency ablation (RFA) of the medial branch nerves that innervate the
facet joints is a well-established treatment modality; however, studies to determine the
optimal radiofrequency ablation temperature are lacking. A wide range (70 to 90 C) has …
[HTML] Catheter Ablation of Atrial Fibrillation: Advent of Second-Generation Technologies
E Buch, K Shivkumar – Journal of the American College of Cardiology, 2015
… and wide-area isolation (5), with or without additional lesion sets targeting non-PV
foci (6) or modifying atrial substrate. All of these techniques initially used
point-by-point ablation with radiofrequency (RF) ablation catheters. …
[HTML] Computed tomography-guided percutaneous trephine removal of the nidus in osteoid osteoma patients: experience of a single center in Brazil
M Petrilli, AA Senerchia, AS Petrilli, HM Lederman… – Radiologia Brasileira, 2015
… Osteoid osteoma: CTguided percutaneous radiofrequency ablation and follow-up in 47 patients.
J Vasc Interv Radiol. 2001;12:717–722. … Peyser A, Applbaum Y, Khoury A, et al. Osteoid osteoma:
CT-guided radiofrequency ablation using a water-cooled probe. Ann Surg Oncol. …
Proton beam therapy for metastatic liver tumors
N Fukumitsu, T Okumura, D Takizawa, H Makishima… – Radiotherapy and Oncology, 2015
… The maximal diameter of the lesions was 1–18 cm (median, 4 cm). Of the 140 patients, 87
had received another form of treatment before PBT, such as chemotherapy, radiofrequency
ablation, transcatheter arterial chemoembolization, and surgery. …
Accuracy of Late Gadolinium Enhancement-Magnetic Resonance Imaging in the Measurement of Left Atrial Substrate Remodeling in Patients With Rheumatic Mitral …
D Zhu, Z Wu, RJ van der Geest, Y Luo, J Sun, J Jiang… – International Heart Journal, 2015
… We enrolled adult patients with rheumatic mitral valve disease and persistent AF who un-
derwent open-heart surgery for mitral valve replacement with concurrent radiofrequency
ablation for AF at our institution between February 2013 and March 2014. …
Predictive value of nodule size and differentiation in HCC recurrence after liver transplantation
GG Piero, P Domenico, F Di Benedetto, M Elena… – Surgical Oncology, 2015
… Generally, radiofrequency ablation (RFA) was proposed in cases of a single tumor less than 3
cm, whereas a single tumor > 3 cm or multifocal lesions in patients with impaired liver function
were directed instead to treatment with trans-arterial chemoembolization (TACE). …
Radiofrequency ablation or stripping of large-diameter incompetent great saphenous varicose veins with C2 or C3 disease
EV Shaidakov, AG Grigoryan, EA Ilyukhin, VL Bulatov… – Journal of Vascular Surgery: …, 2015
Objective The objectives of this study were to compare the results of radiofrequency ablation
(RFA) and stripping for large-diameter varicose target veins for the period of 1 year, based
on a composite end point; to analyze the pain severity on a digital rating scale for 7 days …
Clinical outcomes and risk factors of hepatocellular carcinoma treated by liver transplantation: A multi-centre comparison of living donor and deceased donor …
Z Hu, Z Qian, J Wu, J Zhou, M Zhang, L Zhou, S Zheng – Clinics and Research in …, 2015
… HCC: hepatocellular carcinoma; LDLT: living donor liver transplantation; DDLT: deceased donor
liver transplantation; GWRW: graft weight/recipient weight; TACE: transcatheter arterial
chemoembolisation; RFA: radiofrequency ablation; PEI: percutaneous ethanol injection; ICU …
[PDF] Hepatocellular carcinoma treatment strategies–a case-based review
R Alves, MT Gomes, CS Macedo, HP Miranda, F Nery – Journal of Solid Tumors, 2015
… Resection techniques have been refined, from the use of new radiofrequency ablation resection
devices to laparoscopic approaches, both showing to diminished blood loss [1, 2]. A recent
meta-analysis showed that laparoscopic approach decreases blood loss, transfusion …
Complex Regional Pain Syndrome (CRPS/RSD)
Skin sympathetic function in complex regional pain syndrome type 1
A Poudel, M Asahina, Y Fujinuma, Y Yamanaka… – Clinical Autonomic …, 2015
… 10.1007/s10286-015-0314-x. Copyright information. Abstract. Purpose. Cutaneous
sympathetic pathophysiology in complex regional pain syndrome type 1 (CRPS-1) is
not yet completely understood. To evaluate cutaneous sympathetic …
Substance P spinal signaling induces glial activation and nociceptive sensitization after fracture
WW Li, TZ Guo, X Shi, Y Sun, T Wei, DJ Clark… – Neuroscience, 2015
… hypersensitivity. Abstract. Tibia fracture in rodents induces substance P
(SP)-dependent keratinocyte activation and inflammatory changes in the hindlimb,
similar to those seen in complex regional pain syndrome (CRPS). In …
Economic impact of mgnregp on rural livelihood security in tumkur district, karnataka–a sam analysis
CHR Gowda – 2015
… Item Type: Thesis (Masters). Divisions: RP-Market Institutions and Policies. CRPS: CGIAR
Research Program on Policies, Institutions, and Markets. Uncontrolled Keywords: Economic
Impact, MGNREGP, Rural Livelihood Security, Karnataka, SAM analysis. …
[PDF] DMSA-coated Iron Oxide Nanoparticle Greatly Affect the Expression of Genes Coding Cysteine-rich Proteins by its DMSA Coating
L Zhang, X Wang, J Zou, Y Liu, J Wang – Chemical Research in Toxicology, 2015
… times. The results revealed that about one fourth of DEGs coded cysteine-rich proteins
(CRPs) in all cells under each treatment, indicating that the nanoparticles greatly
affected the expressions of CRP-coding genes. Additionally …
Changing appearance using visual illusions improves ownership of the painful hand in complex regional pain syndrome
J Lewis, C McCabe, R Newport – 2015
… Abstract. Background and aims People with Complex Regional Pain Syndrome (CRPS)
experience a diminished sense of ownership of their painful limb. … Thirty nine patients with CRPS
of one arm were randomly allocated to either a control or experimental group. …
The role of genetically‐engineered pigs in xenotransplantation research
DKC Cooper, B Ekser, J Ramsoondar, C Phelps… – The Journal of Pathology, 2015
… This is because of the expression of human complement-regulatory proteins (CRPs) on the
surface of vascular endothelial cells. Pigs have similar CRPs, but these are relatively inefficient
at protecting the pig cells from human complement-mediated injury [13]. …
Individuality: How knowledge of body perception disturbance can inform treatment
J Lewis – 2015
… Lewis, J. (2015) Individuality: How knowledge of body perception disturbance can inform
treatment. In: International Association of the Study of Pain (IASP) CRPS SIG, Zurich, Switzerland,
31 August – 1 September 2015. [img] Preview. PDF 1MB. Abstract. …
Spinal Cord Stimulation (SCS) and Functional Magnetic Resonance Imaging (fMRI): Modulation of Cortical Connectivity With Therapeutic SCS
M Deogaonkar, M Sharma, C Oluigbo, DM Nielson… – … : Technology at the Neural …, 2015
… Methods. Ten patients with complex regional pain syndrome (CRPS) or neuropathic leg pain
underwent thoracic epidural spinal cord stimulator implantation. Stimulation parameters associated
with “optimal” pain reduction were evaluated prior to imaging studies. …
[PDF] Similarity-based semi-local estimation of EMOS models
S Lerch, S Baran – arXiv preprint arXiv:1509.03521, 2015
… The most popular scoring rules providing summary measures of predictive performance are the
logarithmic score, ie, the negative logarithm of the predictive PDF evaluated at the verifying
observation, and the continuous ranked probability score (CRPS; Gneiting and Raftery …
Review of Plastic Surgery
DW Buck II – 2015
[PDF] Independent CRP-Commissioned External Evaluation of the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH)
J Compton, D McLean, B Emmens, M Balagamwala – 2015
… development partners (IFPRI, 2011). CRPs are not legal entities and therefore legal
and financial responsibility for A4NH ultimately rests with the lead CGIAR Center
and its Board of Trustees (IFPRI- BOT). 2. IFPRI is legally …
[PDF] Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis
C Compagnone, F Tagliaferri – Acta Bio Medica Atenei Parmensis, 2015
… Different diseases could lead to neuro- pathic pain including postsurgical pain, post-herpetic
neuralgia (PHN), spinal cord stenosis (SCS), Complex Regional Pain Syndrome (CRPS), Diabetic
peripheral neuropathy (DPN), and chemotherapy induced pe- ripheral neuropathy. …
Traumatic Life Events and Psychopathology in a High Risk, Ethnically Diverse Sample of Young Children: A Person-Centered Approach
MJ Hagan, MJ Sulik, AF Lieberman – Journal of abnormal child psychology, 2015
… Conditional response probabilities (CRPs) are defined as the probability that an
individual from a specific latent class will endorse an item. CRPs provide … across
classes. CRPs for the exploratory LCA model are shown in Fig. …
Two placebo-controlled, randomized withdrawal studies to evaluate the fentanyl 1-day patch in opioid-naïve patients with chronic pain
T Arai, Y Kashimoto, Y Ukyo, Y Tominaga, K Imanaka – Current Medical Research …, 2015
… study]) and the other study included opioid-naïve subjects with neuropathic pain (post- herpetic
neuralgia, complex regional pain syndrome [CRPS], or chronic postoperative pain; … included: had
osteoarthritis, low back pain, post-herpetic neuralgia, CRPS, or chronic …
[PDF] Challenges of Peripheral Nerve Stimulator Implantation in a Patient with New Onset Thrombocytopenia
S Thompson
… We present a patient with complex regional pain syndrome (CRPS)-like symptoms of the lateral
femoral cutaneous nerve after laparoscopic hysterectomy who underwent successful
ultrasound-guided PNS trial using SCS leads and unfortunate delayed implantation due to …
Improving student learning via mobile phone video content: Evidence from the BridgeIT India project
M Wennersten, ZB Quraishy, M Velamuri – International Review of Education
[PDF] The Association Between Soft Tissue Releases and Bony Resections Performed During Total Knee Arthroplasty and Patients’ Pain and Satisfaction Postoperatively
M Carter – 2015
Page 1. Western University Scholarship@Western Electronic Thesis and Dissertation Repository
September 2015 The Association Between Soft Tissue Releases and Bony Resections Performed
During Total Knee Arthroplasty and Patients’ Pain and Satisfaction …
[PDF] Parthasarathy Rao and Cynthia Bantilan. 2015. Grain Legumes Production, Consumption and Trade Trends in Developing Countries
S Nedumaran, P Abinaya, P Jyosthnaa, B Shraavya
… Markets (PIM). Financial support by CRPs Grain Legumes and Policies, Institutions
and Markets are gratefully acknowledged. This working paper has gone through
the standard peer-review procedure of ICRISAT. The authors …
NEUROMODULATORY DEVICES, SYSTEMS, AND METHODS FOR TREATING FIBROMYALGIA
AR Rezai, M Deogaonkar – US Patent 20,150,251,008, 2015
… In subjects with fibromyalgia as well as other conditions (eg, hot flashes, CRPS, etc.),
clinicians have used pharmacological blockade of the sympathetic nervous system, and
in particular the stellate ganglion, to achieve some clinical benefit. …
Fibromyalgia
Psychiatric Disorders in Young Adults Diagnosed with Juvenile Fibromyalgia in Adolescence.
NR Cunningham, ST Tran, AM Lynch-Jordan, TV Ting… – The Journal of …, 2015
OBJECTIVE: Adolescents with juvenile-onset fibromyalgia (JFM) have increased rates of
psychiatric disorders, but to our knowledge no studies have examined psychiatric disorders
in adolescents with JFM when they enter young adulthood. This study examined the …
Fibromyalgia beyond reductionism. Heart rhythm fractal analysis to assess autonomic nervous system resilience
C Lerma, LA Martinez-Martinez, N Ruiz, A Vargas… – Scandinavian Journal of …, 2015
Objectives: The prevailing linear reductionist medical model seems unable to explain
complex multisymptomatic illnesses such as fibromyalgia (FM) and similar maladies.
Paradigms derived from the complexity theory may provide a coherent framework for …
Exploring the role of peripheral mechanisms: An evaluation of a theory-based approach to reducing symptoms of fibromyalgia
K Mooney – 2015
Abstract: This mixed method study presented an integrative approach for the treatment of
fibromyalgia, the rationale that justifies the approach, and an evaluation of two integrated
components of this protocol designed to mitigate symptoms of fibromyalgia. Considering …
Chronic Widespread Back Pain is Distinct from Chronic Local Back Pain: Evidence from Quantitative Sensory Testing, Pain Drawings, and Psychometrics.
A Gerhardt, W Eich, S Janke, S Leisner, RD Treede… – The Clinical journal of pain, 2015
… Therefore, this study compared quantitative-sensory-testing (QST) profiles of
non-specific chronic back pain patients with CLP (n=48) and CWP (n=29) with
pain-free controls (PCs, n=40) and Fibromyalgia patients (FMS, n=90). …
Meta-analytic evidence for decreased heart rate variability in chronic pain implicating parasympathetic nervous system dysregulation.
LM Tracy, L Ioannou, KS Baker, SJ Gibson… – PAIN, 2015
… frequency HRV in chronic pain, implicating a decrease in parasympathetic activation.
These effects were heavily influenced by fibromyalgia studies. Future research would
benefit from wider use of standardised definitions of …
[HTML] Analgesic effect of cathodal transcranial current stimulation over right dorsolateral prefrontal cortex in subjects with muscular temporomandibular disorders: study …
RA Brandão Filho, AF Baptista, RAFS Brandão… – Trials, 2015
… In a fibromyalgia study using transcranial magnetic stimulation (TMS), the authors found higher
thresholds in both sides of the resting motor cortex with lower up regulation responses.
Furthermore, they found lower intracortical facilitation and inhibition. …
Clinical Research Methodology 1: Study Designs and Methodologic Sources of Error
DI Sessler, PB Imrey – Anesthesia & Analgesia, 2015
… The distinction can be nonobvious. For example, consider a study in which investigators compared
anesthetic requirement in patients with and without fibromyalgia. … But, in fact, fibromyalgia is the
exposure in this study and anesthetic requirement is the outcome. …
[HTML] Economic evaluation in chronic pain: a systematic review and de novo flexible economic model
W Sullivan, M Hirst, S Beard, D Gladwell, F Fagnani… – The European Journal of …, 2015
… While the attributes and management of specific diseases associated with chronic pain, such
as fibromyalgia and osteoarthritis, and different analgesic requirements for neuropathic versus
other chronic pain may have justifiably led to modelling heterogeneity, clinical …
[PDF] Evaluation of the Immediate Effect of Auricular Acupuncture on Pain and Electromyographic Activity of the Upper Trapezius Muscle in Patients with Nonspecific Neck …
ACO Silva, DA Biasotto-Gonzalez, DM Santos… – … -Based Complementary and …, 2015
… NS-NP could contribute to the following: (i) a standardization of the points to be used as stimuli
for the treatment of abnormalities caused in this muscle by mechanical injuries, myofacial tension
(with or without trigger-points), and systemic diseases such as fibromyalgia; (ii) an …
Ehlers Danlos syndrome and gastrointestinal manifestations: a 20‐year experience at Mayo Clinic
AD Nelson, MA Mouchli, N Valentin, D Deyle… – Neurogastroenterology & …, 2015
… hernia,[7] rectal evacuation disorder,[8] diverticulosis, gastritis,[9] constipation, diarrhea, nausea,
vomiting, abdominal pain, and reflux disease.[10] Several non-musculoskeletal symptoms often
found in patients with functional GI disorders such as fibromyalgia, fatigue, cognitive …
[HTML] Real-life assessment of the validity of patient global impression of change in fibromyalgia
E Rampakakis, PA Ste-Marie, JS Sampalis, A Karellis… – RMD Open, 2015
Objectives Patient Global Rating of Change (GRC) scales are commonly used in routine
clinical care given their ease of use, availability and short completion time. This analysis
aimed at assessing the validity of Patient Global Impression of Change (PGIC), a GRC …
[HTML] Increased Risk of Coronary Heart Disease in Patients with Primary Fibromyalgia and Those with Concomitant Comorbidity—A Taiwanese Population-Based Cohort …
CH Su, JH Chen, JL Lan, YC Wang, CH Tseng, CY Hsu… – PLOS ONE, 2015
Objectives Fibromyalgia has seldom been associated with coronary heart disease (CHD).
The aim of this study was to evaluate the risk of CHD in patients with fibromyalgia. Methods
We used a dataset of one million participants, systemically scrambled from the Taiwanese …
[HTML] Group cognitive-behavioral therapy for chronic pain adults: review of Brazilian trials
LF Kirchner, CC Jorge, MJD Reis – Revista Dor, 2015
… 26 . With regard to studied population, table 1 shows predominance of females in all studies,
being fibromyalgia (FM) the most frequent diagnosis. Nevertheless, literature … assertiveness,
3. (6 to 8), Fibromyalgia (100%), VAS. LSSI. RAS. Lorençatto …
[HTML] Chronic Pain Pharmacological Treatment in Patients with Depressive Disorders
C Aurilio, MC Pace, MB Passavanti, V Pota, P Sansone… – Journal of Psychiatry, 2015
… Patients with fibromyalgia present a reduced dopamine presynaptic activity in great many
brain regions, included hippocampus. Neurocircuits and neurochemistry. … [50] published
a review on amitriptyline for neuropathic pain and fibromyalgia. …
Medical Marijuana Patient Counseling Points for Healthcare Professionals Based on Trends in the Medical Uses, Efficacy, and Adverse Effects of Cannabis-Based …
JR Parmar, BD Forrest, RA Freeman – Research in Social and Administrative …, 2015
… All three medications have similarly been used in improving sleep, fibromyalgia, rheumatoid
arthritis associated pain, and spasticity in MS. A complete list of medical uses and included
publications can be reviewed in Table 5. Table 5. … Fibromyalgia, 1 16, 16, …
Identification and description of controlled clinical trials published in Physiotherapy journals in Spain
M Turrillas, M Sitjà‐Rabert, H Pardo… – Journal of Evaluation in …, 2015
… 16.7% of the identified studies were multicentric. Traumatology and orthopaedics was the most
studied field (33.3%) followed by neurology (15.4%). The most researched health problems were
back pain (17.24%) fibromyalgia, arthrosis and stroke (6.8% each). …
[HTML] Serum calprotectin (S100A8/9): an independent predictor of ultrasound synovitis in patients with rheumatoid arthritis
J Hurnakova, J Zavada, P Hanova, H Hulejova, M Klein… – Arthritis Research & …, 2015
… which is obtained by using several composite indexes [4–7]. Nevertheless, a clinical examination
might lack sensitivity in patients with mild synovitis, be limited in patients with established
deformities, and be overestimated in patients with concomitant fibromyalgia or other …
[HTML] Systematic review of the measurement properties of self-report physical activity questionnaires in healthy adult populations
Z Silsbury, R Goldsmith, A Rushton – BMJ Open, 2015
… 6 The review found strong evidence for effectiveness within cardiovascular disease, type 2
diabetes and obesity; and strong evidence for improved symptom management and quality of
life for patients with cancer, osteoarthritis, osteoporosis, fibromyalgia and depression. …
[PDF] Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis
C Compagnone, F Tagliaferri – Acta Bio Medica Atenei Parmensis, 2015
… JOP 2003; 4 (1): 1-10. 4. Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Ami- triptyline for
neuropathic pain and fibromyalgia in adults. … Review. 5. Moore RA, Wiffen PJ, Derry S, Toelle
T, Rice AS. Gabapen- tin for chronic neuropathic pain and fibromyalgia in adults. …
Illness deception
SB Nimmo – Occupational Medicine, 2015
… In a survey of US neuropsychologists, prevalence of malingering and symptom exaggeration
was found to be minor head injury 39%, fibromyalgia/chronic fatigue syndrome 35%, chronic
pain 31%, personal injury cases 29%, disability or workers compensation 30% and …
by admin | Aug 13, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
[HTML] Which Sedation is more Appropriate during Spinal Anesthesia: Propofol or Ketamine-Propofol Combination
H Güleç, ZB Tutal, M Şahap, M Babayiğit, H İnceöz… – Anaesth Pain & Intensive …, 2015
ABSTRACT Background and objective: Spinal anesthesia is a preferred method in daily
practice as it provides muscle relaxation and maintains spontaneous respiration during
surgical procedures. Opiods, midazolam, ketamine, propofol and dexmedetomidine are …
[PDF] Evaluation of Use of Ketamine Hydrochloride for Induction of Anaesthesia in Rabbits with Experimentally Induced Unilateral Ureteral Obstruction
RI Udegbunam, KC Ogbanya, SO Udegbunam… – 2015
ABSTRACT This study investigated the anaesthetic characteristics of ketamine
hydrochloride in rabbits with Unilateral Ureteral Obstruction (UUO). Two groups of rabbits (B
and C) were anaesthetized with 30 mg kgG1 ketamine intravenously (IV) on days 7 and …
Case 62: What Are the Safety Data for This Formulation?
JG Brock-Utne – Clinical Research, 2015
… Discussion We were faced with this problem when we wanted to use ketamine intrathecally. …
References 1. Brock-Utne JG, Mankowitz E, Kallichurum S, Downing JW. Effects of intrathecal
saline and ketamine with or without preservatives on the spinal nerve roots of monkeys. …
[HTML] Ligands Binding to Cell Surface Ganglioside GD2 Cause Src-Dependent Activation of N-Methyl-D-Aspartate Receptor Signaling and Changes in Cellular Morphology
W Tong, M Maira, M Gagnon, HU Saragovi – PLOS ONE, 2015
… For pharmacological inhibition, the Src kinase inhibitor PP2 (20 μM) (Enzo Life Science),
NMDA-R antagonist ketamine (Bioniche Animal Health) (20 μM) or the PKA inhibitor H-89 (Sigma)
(20 ng/ml) were added to the resting cells 30 minutes before the indicated treatments. …
[PDF] Development of Certified Reference Materials of Drug Abuse (Heroin, Etc) for Elimination of Measurement Error in Forensic Drugs
F Su, X Dai, H Li – Pharm Anal Acta, 2015
… For the first time, we developed 9 illicit drug CRMs, including methamphetamine, heroin,
ketamine and others. … CRMs Column Mobile phase Acetonitrile:water Flow Rate (mL/min)
Injection volume(uL) DAD (nm) Ketamine hydrochloride a 40:60* 1.5 20 210 …
[HTML] AdHu5Ag85A Respiratory Mucosal Boost Immunization Enhances Protection against Pulmonary Tuberculosis in BCG-Primed Non-Human Primates
M Jeyanathan, Z Shao, X Yu, R Harkness, R Jiang, J Li… – PLOS ONE, 2015
… Animals were euthanized first by anesthesia with ketamine (im 10 mg/kg) and then by a lethal
dose injection of sodium pentobarbital (iv 100 mg/kg). Experimental animals and handling. …
Animals were anesthetized with ketamine (10 mg/kg) before handling. …
The relative contribution of urine extravasation to elevate plasma creatinine levels in acute unilateral ureteral obstruction.
ME Chua, J Mendoza, IV See, E Esmena, D Aguila… – Canadian Urological …, 2015
… Under sedation with isoflurane inhalation, all rats were subsequently anesthetized with
intraperitoneal (IP) ketamine (100 mg/kg) plus xylazine (15 mg/kg) after being preopera- tively
hydrated by subcutaneous injection of 5 cc saline mixed with indigo carmine (5,5 …
P-193TRACHEAL RESECTION WITH PATIENT UNDER LOCAL ANAESTHESIA AND SEDATION
FP Caronia, D Loizzi, A Fiorelli – Interactive CardioVascular and Thoracic Surgery, 2015
… During the procedure the patient remained awake in conscious sedation achieved by bolus
of ketamine and midazolam. … During the entire procedure the patient remained awake in
conscious sedation achieved by bolus of ketamine and midazolam. …
[HTML] Neural Resolution of Formant Frequencies in the Primary Auditory Cortex of Rats
C Honey, J Schnupp – PLOS ONE, 2015
… Anesthesia was induced by intraperitoneal injection of ketamine (Ketaset; Fort Dodge Animal
Health, Overland Park, Kansas, USA) and medetomidine (Domitor, Pfizer, Walton Oaks, Surrey,
UK), and maintained with intraperitoneal infusions of ketamine, medetomidine and …
Aerobic training normalizes autonomic dysfunction, HMGB1 content, microglia activation and inflammation in hypothalamic paraventricular nucleus of SHR
GS Masson, AR Nair, PPS Soares, LC Michelini… – American Journal of …, 2015
… Analysis of Cardiovascular Parameters and Baroreflex Function 135 At the end of the protocols,
rats were anaesthetized (ketamine, 80 mg.kg−1 plus 136 … calculated as BrS = –(P2×P3)/4. 152
After the physiologic measurements, animals were anesthetized (ketamine, 80 153 …
Combination of intravenous S-ketamine and oral tranylcypromine in treatment-resistant depression: A case report
L Bartova, SE Vogl, M Stamenkovic… – European …, 2015
Abstract Ketamine, a rapid-acting antidepressant and anti-suicidal agent, is thought to
increase brain monoamine levels by enhancing monoamine release or inhibiting
presynaptic monoamine-reuptake. Here we present two female inpatients suffering from …
Ketamine Abuse Syndrome: Hepatobiliary and Urinary Pathology Among Adolescents in Flushing, NY.
JW Wang, V Kivovich, L Gordon – Pediatric Emergency Care, 2015
Objectives: Ketamine is a recreational drug widely abused in East Asia and also in certain
subpopulations of the United States. Many US clinicians are unaware of abuse symptoms,
leading to misdiagnosis and missed opportunities for intervention. We will discuss clinical …
Ketamine Abuse Syndrome
JW Wang, V Kivovich, L Gordon – 2015
Objectives: Ketamine is a recreational drug widely abused in East Asia and also in certain
subpopulations of the United States. Many US clinicians are unaware of abuse symptoms,
leading to misdiagnosis and missed opportunities for intervention. We will discuss clinical …
Ondasetron Is More Likely Than Ketamine to Cause Ventricular Tachycardia
P Marzuillo, I Rabach, E Barbi – Pediatric Emergency Care, 2015
We read with interest the article published in the October 2014 issue of Pediatric Emergency
Care entitled “Ventricular tachycardia after ketamine sedation for fracture reduction.” Stukus
et al 1 described a 10-year-old female patient who experienced asymptomatic ventricular …
The development of paper microfluidic devices for presumptive drug detection.
G Musile, L Wang, J Bottoms, F Tagliaro, B McCord – Analytical Methods, 2015
… different lanes. A different colorimetric reaction occurs within each lane, permitting
the multiplexed detection of a variety of different compounds, including cocaine,
opiates, ketamine, and various phenethyl amines. Furthermore …
[PDF] GLP-1 increases pre-ovulatory LH source and the number of mature follicles, as well as synchronizing the onset of puberty in female rats
V Outeiriño-Iglesias, M Romaní-Pérez… – Endocrinology, 2015
… bregma. Cannulation was performed under ketamine/xylazine anesthesia (50
mg/kg and 5 mg/kg, respectively) and the correct placement of the cannula was
confirmed by postmortem injection of trypan- blue 0.5% (Sigma, St. …
[HTML] Bispectral index-guided induction of anesthesia by ketofol infusion provides the same cardiovascular stability like that of etomidate infusion
HF Soliman – Ain-Shams Journal of Anaesthesiology, 2015
… Get Permissions. Abstract, Introduction Various techniques have been tried to maintain
cardiovascular stability with anesthesia induction. This study compares the cardiovascular effects
of propofol-ketamine mixture versus etomidate during the induction of anesthesia. …
[PDF] Anti-osteoporotic activity of ethanol extract of Terminalia arjuna (Roxb.) Wight & Arn. on ovariectomized rats
A Trivedi, HR Katti, MH Shalavadi, A Ramkishan… – Indian Journal of Natural …, 2015
… Estrogen and Ketamine obtained from Neon Laboratories Ltd. Mumbai, India. … After seven days
of acclimation, the rats were ovariectomized or Sham operated and then anesthetized with
Ketamine HCL (50 mg/kg, ip); the ovaries were removed bilaterally. …
[HTML] Long-Term Extensive Ectopic Hair Growth on the Spinal Cord of Mice from Transplanted Whisker Follicles
W Cao, L Li, S Mii, Y Amoh, F Liu, RM Hoffman – PloS one, 2015
… Animals were anesthetized by intramuscular injection of a 0.02 ml solution of 20 mg/kg
ketamine, 15.2 mg/kg xylazine, and 0.48 mg/kg acepromazine maleate. … Non-transgenic nude
mice were anesthetized with a ketamine mixture (described above). …
Retinal functional alterations in mice lacking intermediate filament proteins glial fibrillary acidic protein and vimentin
KA Wunderlich, N Tanimoto, A Grosche, E Zrenner… – The FASEB Journal, 2015
… Mice were dark- adapted (DA) overnight before the experiments and anesthetized with a
subcutaneous injection of a mixture of ketamine, xylazine, and physiologic saline. Ketamine
and xylazine were given at 66.7 and 11.7 mg/kg body weight, respectively. …
Radiofrequency Ablation (RFA)
[PDF] Electrophysiological Bases of Torsion and Suction in the Continuous Cardiac Band Model
J Trainini, B Elencwajg, N López-Cabanillas… – Anat Physiol, 2015
… early diastolic filling by the suction effect. We investigated the electrophysiological
basis of this mechanism, by electroanatomical left ventricular endoepicardial mapping
(EEM) in five patients, during radiofrequency ablation. …
Uninterrupted Apixaban Safe and Effective in AF Ablation
EH Nichols – MD Conference Express, 2015
… Summary. According to a multicenter, prospective registry study, uninterrupted apixaban used
in the periprocedural setting of radiofrequency catheter ablation in patients with atrial fibrillation
does not increase the risk of bleeding compared with uninterrupted warfarin. …
Lateral Femoral Cutaneous Nerve Block
P Tumber, PWH Peng – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… Pain Pract. 2011;11(3):302–8.PubMedView Article; 15. Fowler IM, Tucker AA, Mendez RJ.
Treatment of meralgia paresthetica with ultrasound-guided pulsed radiofrequency ablation of
the lateral femoral cutaneous nerve. Pain Pract. 2012;12(5):394–8.PubMedView Article. …
Sacroiliac Joint
PWH Peng – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… Am J Phys Med Rehabil. 2006;85:997–1006.PubMedView Article; 6. Roberts S, Burnham R,
Ravichandiran K, Agur A, Loh E. Cadaveric study of sacroiliac joint innervation: implications
for diagnostic blocks and radiofrequency ablation. Reg Anesth Pain Med. …
Ilioinguinal, Iliohypogastric, and Genitofemoral Nerve Blocks
D Bugada, PWH Peng – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… 2014;2014:371703. doi:10. 1155/ 2014/ 371703.PubMed CentralPubMed; 47. Terkawi AS,
Romdhane K. Ultrasound-guided pulsed radiofrequency ablation of the genital branch of the
genitofemoral nerve for treatment of intractable orchalgia. Saudi J Anaesth. …
[HTML] Neoplastic disease after liver transplantation: focus on de novo neoplasms
P Burra, KI Rodríguez-Castro – World J Gastroenterol, 2015
… Prognosis seems dismal according to reported cases, despite tapering of
immunosuppression, transarterial chemoembolization, radiofrequency ablation, hepatic
resection, or retransplantation. Strategies for preventing this neoplasm …
Pediatric Nuclear Medicine
PJ Koo, FD Grant – Nuclear Medicine and PET/CT Cases, 2015
European Heart Rhythm Society, EHRA EUROPACE-CARDIOSTIM2015
RP Giugliano, S Bansilal, MP Bonaca, M Cavender… – MD Conference Express, 2015
… Two registry studies examined the use of non–vitamin K antagonist oral anticoagulant
use in patients with atrial fibrillation (AF) undergoing radiofrequency catheter ablation
(RFA). The first determined that AF patients can safely …
[HTML] Propensity Score Matching Analysis of Changes in Alpha-Fetoprotein Levels after Combined Radiotherapy and Transarterial Chemoembolization for Hepatocellular …
Y Jeong, SM Yoon, S Han, JH Shim, KM Kim, YS Lim… – PLOS ONE, 2015
Advertisement. …
Iron Oxide Based Nanoparticles for Multimodal Imaging and Magnetoresponsive Therapy
N Lee, D Yoo, D Ling, MH Cho, T Hyeon, J Cheon – Chemical Reviews, 2015
… When a resonant radiofrequency is irradiated, the nucleus absorbs the energy and the
number of the spins with a higher-energy state increases. … During the relaxation process,
the excited nuclei emit a weak radiofrequency that can be detected. …
… Radiofrequency Ablation: Comparison of Transarterial Chemoembolization Alone and Combined Therapy with Transarterial Chemoembolization and Radiofrequency …
D Hyun, SK Cho, SW Shin, KB Park, HS Park… – CardioVascular and …, 2015
Purpose To report the results of combined therapy with transarterial chemoembolization
(TACE) and radiofrequency ablation (RFA) for early stage hepatocellular carcinoma (HCC)
considered infeasible for ultrasound (US)-guided RFA in comparison with those of TACE …
The procedure outcome of laparoscopic resection for’small’hepatocellular carcinoma is comparable to vlaparoscopic radiofrequency ablation
M Casaccia, G Santori, G Bottino, P Diviacco… – 2015
Background: The aim of this study was to compare the effectiveness of laparoscopic liver
resection (LLR) and laparoscopic radiofrequency ablation (LRFA) in the treatment of small
nodular hepatocellular carcinoma (HCC). Patients And Methods: We enrolled 50 cirrhotic …
PTH-177 Radiofrequency ablation for complicated barrett’s oesophagus: experience of a tertiary centre in northern ireland at 5 years
P Hall, O Reed, I Mainie – Gut, 2015
Abstract Introduction The 2013 British Society of Gastroenterology (BSG) guideline supports
first line use of endoscopic therapy in patients with dysplastic Barrett’s oesophagus or
intramucosal carcinoma (IMC). 1 Endoscopic mucosal resection (EMR) and …
Observations on Attenuation of Local Electrogram Amplitude and Circuit Impedance During Atrial Radiofrequency Ablation: An In vivo Investigation Using a Novel …
A Bhaskaran, W Chik, C Nalliah, J Pouliopoulos… – Journal of Cardiovascular …, 2015
Aims To define the temporal characteristics of atrial lesion growth (lesion surface area), local
electrogram amplitude attenuation and circuit impedance decrement during in vivo Radio
Frequency (RF) ablation with direct endocardial visualization (DEV).
[HTML] Intraductal Radiofrequency Ablation Followed by Locoregional Tumor Treatments for Treating Occluded Biliary Stents in Non-Resectable Malignant Biliary Obstruction …
XH Duan, YL Wang, XW Han, JZ Ren, TF Li, JH Zhang… – PloS one, 2015
Objectives To determine the safety and feasibility of intraductal radiofrequency ablation
(RFA) followed by locoregional tumor treatments in patients with non-resectable malignant
biliary obstruction and stent re-occlusion. Methods Fourteen patients with malignant biliary …
Sorafenib combined with radiofrequency ablation in the treatment of a patient with renal cell carcinoma plus primary hepatocellular carcinoma
G Gang, Y Hongkai, Z Xu – 2015
The combination of renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC) is
extremely rare, and the prognosis for patients with these two cancers is poor. In the past
decade, molecular targeted therapy and radiofrequency ablation (RFA) have emerged …
RADIOFREQUENCY ABLATION FOR BENIGN THYROID NODULES-A LOOK TOWARDS THE FUTURE OF INTERVENTIONAL THYROIDOLOGY
MA Lupo – Endocrine Practice, 2015
Welcome to the new Endocrine Practice website. Click HERE to access your account and reset
your password if this is your first visit. The IP ranges for your institution have already been added
to your account. You may wish to review this information under the Institutional …
[PDF] Clinical Effect of Percutaneous Radiofrequency Ablation for Residual Lung Metastases from Breast Cancer After Systemic Chemotherapy
Y Wang, X Lu, Y Wang, J Zhou – Journal of the College of Physicians and Surgeons …, 2015
Breast Cancer (BC) is the most common malignant tumor in women and it is the leading cause
of death in women.1 The earliest and most frequent site of BC metastasis is the lungs and
bones, and no more than 5 – 20% of cases have only liver metastases.2 Metastatic BC …
Recanalization of obstructed metallic uncovered biliary stent using endobiliary radiofrequency ablation
N Musquer, E Ménager Tabourel, D Luet… – Gastrointestinal Endoscopy, 2015
We present the case of a 57-year-old woman with a history of hilar cholangiocarcinoma type
3A of the Bismuth classification. A right hepatectomy after right portal embolization was
planned. Finally, because peritoneal carcinomatosis was diagnosed during surgery, a …
Ventricular premature depolarization ablation and reversal of nonischemic cardiomyopathy
RC Arroyo, S Maeda, BP Betensky, P Santangeli, D Lin… – Interventional Cardiology, 2015
… 4.4 cm. CM: Cardiomyopathy; LVDD: Left ventricular end-diastolic dimension; LVEF:
Left ventricular ejection fraction; RFA: Radiofrequency ablation; VPD: Ventricular
premature depolarization. Ventricular premature depolarization …
Complex Regional Pain Syndrome (CRPS/RSD)
Lumbar Plexus and Femoral Nerve Block. Traditional and Ultrasound Guided Techniques
D Jankovic, J Kessler, AT Gray – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… 5. Arterial occlusive disease and poor perfusion in the lower extremities. 6. Complex regional
pain syndrome (CRPS) types I and II. 7. Postamputation pain. 8. … 3. Prophylaxis against complex
regional pain syndrome (CRPS). Contraindications. Specific. 1. …
Superior Cervical Ganglion Block
D Jankovic – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… Therapeutic [ 3 ]. 1. Migraine [ 4 ], cluster headache, and headaches of cervical origin. 2. Complex
regional pain syndrome (CRPS) in the head region. 3. Perfusion disturbances and vasospastic
diseases. 4. Central poststroke syndrome (contralateral block!). 5. Facial pain. 6. …
Brachial Plexus Blocks Above the Clavicle Traditional Techniques
D Jankovic – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… 10–20 mL local anesthetic – eg, 0.2–0.375 % ropivacaine or 0.25 % bupivacaine (0.25 %
levobupivacaine) in post-herpetic neuralgia, vascular diseases and injuries, complex
regional pain syndrome (CRPS) types I and II, post-amputation pain. …
Stellate Ganglion Block
A Bhatia, PWH Peng – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… AACN Clin Issues. 2005;16:320–32.PubMedView Article; 25. Stanton-Hicks MD, Burton
AW, Bruehl SP, et al. An updated interdisciplinary clinical pathway for CRPS: report of
an expert panel. Pain Pract. 2002;2:1–16.PubMedView Article; 26. …
[HTML] The efficacy of different doses of Midazolam added to Lidocaine for upper extremity Bier block on the sensory and motor block characteristics and postoperative pain
A Honarmand, M Safavi, K Nemati, P Oghab – Journal of Research in Pharmacy …, 2015
… 24. 25. Coderre TJ, Xanthos DN, Francis L, Bennett GJ. Chronic post-ischemia pain (CPIP): A
novel animal model of complex regional pain syndrome-type I (CRPS-I; reflex sympathetic
dystrophy) produced by prolonged hindpaw ischemia and reperfusion in the rat. …
Complications of Peripheral Nerve Blocks
D Xu, A Hadzic – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… Coderre TJ, Xanthos DN, Francis L, Bennett GJ. Chronic post–ischemia pain (CPIP): a novel
animal model of complex regional pain syndrome–type I (CRPS–I; reflex sympathetic dystrophy)
produced by prolonged hindpaw ischemia and reperfusion in the rat. Pain. …
Functional neurological symptoms
A Carson, J Stone – Landmark Papers in Neurology, 2015
[PDF] ifssh
H THeRAPy looK liKe iN, C TReATmeNT
Page 1. ifssh ezine CoNNeCTiNG ouR GloBAl HAND suRGeRy FAmily
www.ifssh.info volume 5 issue 3 aUgUSt 2015 WHAT Does THe PRACTiCe oF HAND
THeRAPy looK liKe iN iFsHT memBeR CouNTRies? CoNseRvATive …
Preparation of polydimethylaminoethyl methacrylate grafted attapulgite via ceric ion‐induced redox polymerization
H Xu, H Yang, S Xue, J Pan, Q Ni, F Gong – Journal of Applied Polymer Science, 2015
… interests.[10-12] Surface-initiated graft polymerizations of various monomers onto inorganic
nanoparticles have been reported by using UV-induced polymerization,[13] conventional radical
polymerizations,[14] and controlled/living radical polymerizations (CRPs).[15, 16] CRPs …
Total Elbow Arthroplasty for Distal Humerus Fractures
LS Harmer, J Sanchez-Sotelo – Hand Clinics, 2015
… Mansat et al, 31 2013, 87, 80:7, Age: >65 Isolated #, —, A: 9 B: 8 C: 70, CM: 85 Lat: 1 Discovery:
1, 37.5 (6–106) (100%), 86 (45–100), 29–125/—, Hematoma: 5 CRPS: 2 Skin necrosis: 1 Neuro
injury: 7 Deep infection: 1 Stem #: 1 Stem loosening: 2 Elbow stiffness: 2 Peripros #: 1 …
Sacral roots stimulation in chronic pelvic pain
P Sokal, P Zieliński, M Harat – Neurologia i Neurochirurgia Polska, 2015
… is not recommended because of long-term moderate effects and increased risk of major
complications [2]. The CPP with predominance of neuropathic pain can be the part of
failed-back-surgery syndrome (FBSS) or complex regional pain syndrome (CRPS) which are …
[PDF] Probabilistic temperature forecasting based on an ensemble AR modification
A Möller, J Groß – arXiv preprint arXiv:1508.01397, 2015
… Gneiting et al. (2005) propose to estimate the parameters by optimizing the continuous ranked
probability score (CRPS, Wilks, 2011) over the training data. … EMOS AR-EMOS SLP MAE 2.042
2.036 1.969 CRPS 1.471 1.460 1.407 DSS 3.135 2.908 2.821 …
The value of SPECT/CT in carpal boss
U Bhure, U Hug, MW Huellner, H Grünig, A Zander… – European Journal of …, 2015
… One patient was lost to follow-up after infiltration of CB. One patient had a complete response
to surgery initially but developed a CRPS (complex regional pain syndrome) some weeks after
surgery. … Infiltration with complete response; surgery performed; CRPS during follow-up. 5. …
Neurogenic neuroinflammation in fibromyalgia and complex regional pain syndrome
G Littlejohn – Nature Reviews Rheumatology, 2015
… fibromyalgia. Clinical features of CRPS. Neurogenic inflammation—comprising tissue
swelling, vasomotor changes and marked allodynia—also contributes substantially to
the clinical features of CRPS. … 91. Neuropeptides in CRPS. Increased …
[HTML] Memristive crypto primitive for building highly secure physical unclonable functions
Y Gao, DC Ranasinghe, SF Al-Sarawi, O Kavehei… – Scientific Reports, 2015
… Our novel architecture demonstrates desirable characteristics of PUFs, including uniqueness,
reliability, and large number of challenge-response pairs (CRPs) and desirable characteristics
of strong PUFs. … Number of CRPs. Figure 10: Number of CRPs. …
Methods for Treating GI Syndrome and Graft versus Host Disease
JA Rotolo, RN Kolesnick – US Patent 20,150,216,971, 2015
… Ceramide generated on the surface of endothelium coalesces to form ceramide-rich
platforms (CRPs) that transmit an apoptotic signal (Stancevic B., Kolesnick R.
Ceramide-rich platforms in transmembrane signaling. FEBS Lett. …
Multivariate postprocessing techniques for probabilistic hydrological forecasting
S Hemri, D Lisniak, B Klein – Water Resources Research, 2015
… river Lahn as these values lead to the best climatological forecasts in terms of the contin- uous
ranked probability score (CRPS, see equation (4)). The smaller the catchment, the … of the EMOS
model are estimated by minimization of the CRPS over the training pe- riod. …
Ambiguous anti‐fouling surfaces: Facile synthesis by light‐mediated radical polymerization
CW Pester, JE Poelma, B Narupai, SN Patel, GM Su… – Journal of Polymer Science …, 2015
… the prevention of marine biofouling.[7, 8]. Controlled radical, surface-initiated
polymerizations (SI-CRPs) provide a robust and versatile strategy for the formation
of grafted polymer brushes. A variety of techniques have been …
Fibromyalgia
Off-Label Trazodone Prescription: Evidence, Benefits and Risks
L Bossini, A Coluccia, I Casolaro, J Benbow… – Current Pharmaceutical …, 2015
… depression, insomnia, anxiety (then Gen- eralized Anxiety Disorder, Post-Traumatic Stress
Disorder, Obses- sive-Compulsive Disorder and Panic Disorder), off-label uses (then bulimia,
benzodiazepine abuse, alcohol withdrawal, fibromyalgia, dementia, schizophrenia and …
[PDF] Purification of A1PI from Human Plasma-an Improved Process to Achieve Therapeutic Grade Purity
NA Kumar, KL Rao, Z Chakraborthy, A Giri, KU Devi – J Chromatogr Sep Tech, 2015
… due to congenital A1PI deficiency but as evident from the available literature, due to the multiple
biological activities of A1PI, it has been associated with other lung diseases (cystic fibrosis) and
many non-pulmonary diseases like vasculitis, fibromyalgia, asthma, pancreatitis …
[PDF] Clinical features of musculoskeletal disorders due to hand-held devices
D Sharan – Proceedings 19th Triennial Congress of the IEA, 2015
… Associated Disorder n % Myofascial pain syndrome of neck and upper back 48 69
Thoracic outlet syndrome 34 49 Fibromyalgia syndrome 07 10 Hypothyroidism 02 2.9
Extensor wrist tendinosis 04 5.7 De Quervain’s tenosynovitis 02 2.9 …
[PDF] Outcome of treatment of work related musculoskeletal disorders in on-site clinics in information technology companies)
DSMMR Ranganathan – Proceedings 19th Triennial Congress of the IEA, 2015
… Common diagnosis made were Myofascial Pain Syndrome (49.20%), Fibromyalgia (8.5%),
Thoracic Outlet Syndrome (25.02%), Cubital Tunnel Syndrome (0.16%), Chronic Regional
Pain Syndrome (0.20%), and Wrist Tendinities (3.70%). …
COMPLEX PHYSIOTHERAPEUTIC PROGRAM FOR IMPACT ON INDIVIDUALS WITH CHRONIC PAIN IN THE BACK AND LOW BACK.
YV Pashkunova – Activities in Physical Education & Sport, 2015
… mechanical back pain associated with the work done are charac teristic for men.
Polymyalgia rheumatic, fibromyalgia, osteoporosis and diseases of parathyroid glands
are characteristic for women (Borenstein, 1998). Generally …
[HTML] Animal-Assisted Therapy for People with Chronic Pain
MOT Kristen Counts
… In 2013, a follow-up study was done with fibromyalgia patients (3) . Fibromyalgia is a disorder
characterized by widespread muscle pain that is accompanied by fatigue, sleep, memory, and
mood issues. … Of course, the exercise further decreased my fibromyalgia symptoms. …
[PDF] The barrier of hidden disabilities
Ε Βαβουράκη, Γ Παναγιάρης, Κ Σφλώμος – 2015
… hyperactivity disorder(AD/HD), asthma and allergies, bipolar disorder, psychiatric disorders,
depression, anxiety, cancer, cardiac or respiratory conditions, chronic fatigue syndrome, colour
blindness, cystic fibrosis, diabetes, epilepsy, seizure disorders, fibromyalgia, HIV/AIDS …
Superior Cervical Ganglion Block
D Jankovic – Regional Nerve Blocks in Anesthesia and Pain …, 2015
… number of patients. These observations principally concern patients with
pain-associated depression in chronic pain conditions (various types of headache,
migraines, facial pain, post-nucleotomy pain, fibromyalgia, etc.). In the …
[HTML] Identification of α1-Antitrypsin as a Potential Candidate for Internal Control for Human Synovial Fluid in Western Blot
S Wang, J Zhou, X Wei, P Li, K Li, O Wang, F Wei… – Rheumatology: Current …, 2015
… Arthritis Res Ther 10: R117. Schmechel DE, Edwards CL (2012) Fibromyalgia, mood disorders,
and intense creative energy: A1AT polymorphisms are not always silent. Neurotoxicology
33: 1454-1472. Goldring MB, Goldring SR (2007) Osteoarthritis. …
[PDF] Examining the relationship between childhood victimization, health risk behaviors, and adult physical health outcomes among women on probation and parole.
TR Renn – 2015
… Chartier, Walker & Naimark (2009) Female & Male Obesity OR=1.61 Rohde et al. (2008)
Female Adjusted for age and race Obesity OR=1.84 Alexander et al (1998) Fibromyalgia
Heitkemper et al (2001) Irritable bowel syndrome Rich-Edwards, et al. …
Thalamic Mechanisms Underlying Alpha-Delta Sleep with Implications for Fibromyalgia
S Vijayan, EB Klerman, GK Adler, N Kopell – Journal of Neurophysiology, 2015
Abstract Alpha-delta sleep is the abnormal intrusion of alpha activity (8-13 Hz oscillations)
into the delta activity (1-4 Hz oscillations) that defines slow wave sleep. Alpha-delta sleep is
especially prevalent in fibromyalgia patients and there is evidence suggesting that the …
SP0131 Fibromyalgia: What is New
LJ Crofford – Annals of the Rheumatic Diseases, 2015
Abstract Further clarification of the impact of FM classification criteria has emerged with a
higher prevalence and greater proportion of men identified with the modified 2010 criteria.
This together with ongoing epidemiologic studies has confirmed the relationships …
Pelvic Floor and Urinary Distress in Women with Fibromyalgia
KD Jones, C Maxwell, SD Mist, V King, MA Denman… – Pain Management Nursing, 2015
Abstract Fibromyalgia (FM) patients were recently found to have more symptom burden from
bothersome pelvic pain syndromes that women seeking care for pelvic floor disease at a
urogynecology clinic. We sought to further characterize pelvic floor symptoms in a larger …
[PDF] Effects of transdermal magnesium chloride on quality of life for patients with fibromyalgia: a feasibility study
DJ Engen, SJ McAllister, MO Whipple, SS Cha, LJ Dion… – J Integr Med, 2015
ABSTRACT BACKGROUND: Fibromyalgia is a syndrome characterized by chronic pain,
fatigue, depression, and sleep disturbances. Its primary cause is unclear. Several studies
have reported decreased intracellular magnesium levels in patients with fibromyalgia and …
Neurogenic neuroinflammation in fibromyalgia and complex regional pain syndrome
G Littlejohn – Nature Reviews Rheumatology, 2015
Although fibromyalgia and complex regional pain syndrome (CRPS) have distinct clinical
phenotypes, they do share many other features. Pain, allodynia and dysaesthesia occur in
each condition and seem to exist on a similar spectrum. Fibromyalgia and CRPS can both …
Validation of fibromyalgia survey questionnaire and polysymptomatic distress scale in a Persian population
A Bidari, B Ghavidel-Parsa, AA Maafi, A Montazeri… – Rheumatology International, 2015
Abstract The aim of this study was to assess validity of the fibromyalgia survey questionnaire
(FSQ) and polysymptomatic distress scale (PSD) in an Iranian population. We also sought to
classify the severity levels of fibromyalgia (FM) symptoms according to the PSD scale. …
Health anxiety and depression in patients with fibromyalgia syndrome
M Uçar, Ü Sarp, Ö Karaaslan, AI Gül, N Tanik, HO Arik – Journal of International …, 2015
Methods Patients with FMS and healthy control subjects were recruited. All participants
completed the Health Anxiety Inventory Short Form (HAI-SF) and Beck Depression Inventory
(BDI). Pain was assessed in patients with FMS using the Fibromyalgia Impact …
Subgroups of fibromyalgia patients using the 1990 American College of Rheumatology criteria and the modified 2010 preliminary diagnostic criteria: the al-Ándalus …
V Segura-Jiménez, A Soriano-Maldonado… – Clinical and experimental …, 2015
OBJECTIVES: We aimed to investigate the symptom profiles in subsets of fibromyalgia
patients according to the subgroups created from the satisfaction of the 1990 American
College of Rheumatology (ACR) diagnostic criteria (1990c) and/or the modified 2010 ACR …
Effects of music on pain in patients with fibromyalgia
GB Alparslan, B Babadağ, A Özkaraman, P Yıldız… – Clinical Rheumatology, 2015
Abstract Fibromyalgia syndrome (FMS) is a chronic syndrome characterized by diffuse
musculoskeletal system pain and painful tender points in certain areas of the body. The aim
of the investigation was to determine the effects of music on pain in fibromyalgia patients. …
[HTML] Oral Burning With Dysphagia and Weight Loss
TM Seccia, G Rossitto, LA Calò, GP Rossi – Medicine, 2015
… Accepted June 22, 2015. Collapse Box Abstract. Abstract: Fibromyalgia is a disorder characterized
by an abnormal pain regulation. … We report on the case of a patient with fibromyalgia, who
presented with dysphagia, odynophagia, and glossodynia as prevalent symptoms. …
by admin | Aug 2, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Gender and estrous cycle influences on behavioral and neurochemical alterations in adult rats neonatally administered ketamine
VCM Borella, MV Seeman, RC Cordeiro… – Developmental …, 2015
Abstract Neonatal NMDA receptor blockade in rodents triggers schizophrenia-like
alterations during adult life. Schizophrenia is influenced by gender in age of onset,
premorbid functioning and course. Estrogen, the hormone potentially driving the gender …
Hypothalamic, thalamic and hippocampal lesions in the mouse MCAO model: potential involvement of deep cerebral arteries?
M El Amki, T Clavier, N Perzo, R Bernard, PO Guichet… – Journal of Neuroscience …, 2015
… Anesthetic methods in rodent models of cerebral ischemia impact the infarct volume. In
experimental models developed in rodents, the most used anesthetics are the volatile ones such
as isoflurane or halothane and intraperitoneal (ip) ketamine or barbiturates. …
Targeting the CD80/CD86 costimulatory pathway with CTLA4‐Ig directs microglia toward a repair phenotype and promotes axonal outgrowth
A Louveau, V Nerrière‐Daguin, B Vanhove… – Glia, 2015
… Male LEWIS 1A rats were anesthetized by intramuscular injection of 2% Rompun and 50mg/mL
ketamine (1.6 mL/kg) (PanPharma). … Twenty-eight days after transplantation, grafted-male Lewis
1A rats were deeply anesthetized with Rompun-ketamine (1:4) at 1 mg/kg (ip). …
[PDF] Anti-nociceptive effects of taurine and caffeine in sciatic nerve ligated wistar rats: involvement of autonomic receptors
W Abdulmajeed, BV Owoyele – Journal of African Association of Physiological …, 2015
… (St. Louis MO, USA) while propranolol and prazosin were products of Namco
Chemicals, Amritsr, India. Normal saline and ketamine were purchased from Momrota
pharmacy, opposite University of Ilorin Teaching Hospital’s gate. …
Two Cellular Hypotheses Explaining Ketamine’s Antidepressant Actions: Direct Inhibition and Disinhibition
OH Miller, JT Moran, BJ Hall – Neuropharmacology, 2015
Abstract A single, low dose of ketamine has antidepressant actions in depressed patients
and in patients with treatment-resistant depression (TRD). Unlike classic antidepressants,
which regulate monoamine neurotransmitter systems, ketamine is an antagonist of the N- …
Effect of Piperine on Liver Function of CF-1 albino Mice.
JR Peela, SD Kolla, F Elshaari, F Elshaari, H El Awamy… – Infectious disorders drug …, 2015
… with high fat diet. These mice were anaesthetized with ketamine and halothane and
blood was drawn from each mouse before the study and after three weeks by
cardiocentesis. Serum transaminases (alanine aminotransferase …
[PDF] Correlation between anti-HBs and immunostimulatory cytokines following hepatitis B vaccination in mice
OU Peter, PO OKONKWO, OO John, A Dorathy – 2015
… AM daily. All mice were acclimatized for two weeks. Diazepam injection (Valium,
Roche, USA), and ketamine injection (Ketalar, Popular Pharmaceuticals, Bangladesh)
were procured from Pax Pharmacy, Onitsha. Hepatitis B …
Phosphodiesterase‐4D: an enzyme to remember
R Ricciarelli, E Fedele – British Journal of Pharmacology, 2015
… enzyme isoform is localized in brain regions associated with emesis (eg area postrema and
nucleus of the solitary tract; Cherry and Davis, 1999; Lamontagne et al, 2001; Mori et al, 2010)
and its deletion in transgenic mice reduced the xylazine/ketamine-induced anaesthesia, a …
The effects of tacrolimus on the activity and expression of tissue factor in the rat ovary with ischemia–reperfusion induced injury
UV Ustundag, S Sahin, K Ak, I Keskin… – Reproductive Biology, 2015
… the ovaries. The rats were anesthetized with a combination of ketamine hydrochloride
(60 mg/kg ip.) and xylazine (5 mg/kg ip.). Supplementary injections of ketamine
hydrochloride were given when needed. After anesthesia …
Novel Rat Model for Neurocysticercosis Using Taenia solium
MR Verastegui, A Mejia, T Clark, CM Gavidia… – The American Journal of …, 2015
… Before intracranial inoculation, the rats were anesthetized with 70 mg/kg of ketamine plus
11 mg/kg of xylazine. … Animals were euthanized after being anesthetized with a mixture of
100 mg/kg of ketamine, 10 mg/kg of xylazine, and 3 mg/kg of tramadol. …
Photo of the Day: Low-dose Ketamine Infusions
A Katz – Emergency Medicine News, 2015
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. … This blog serves as a bulletin board for …
[HTML] Impact of Anesthesia Protocols on In Vivo Bioluminescent Bacteria Imaging Results
T Chuzel, V Sanchez, M Vandamme, S Martin, O Flety… – PLOS ONE, 2015
… S. aureus Xen36 strain. Bioluminescence imaging was performed on mice
anesthetized by either ketamine/xylazine (with or without oxygen supplementation),
or isoflurane carried with air or oxygen. Total flux emission was …
Sedative and Anxiolytic Agents
SI Ganzberg, S Wilson – Oral Sedation for Dental Procedures in Children, 2015
… The salient fea- tures of nitrous oxide, chloral hydrate, meperidine, midazolam, antihista- mines,
and ketamine are discussed in relation to sedating children for dental procedures. … Studies
using ketamine administered orally have resulted in mixed results. …
[HTML] Fractionated Radiation Exposure of Rat Spinal Cords Leads to Latent Neuro-Inflammation in Brain, Cognitive Deficits, and Alterations in Apurinic Endonuclease 1
MAS Kumar, M Peluso, P Chaudhary, J Dhawan… – PLOS ONE, 2015
… Ethics Statement. All exposures to radiation were done under ip anesthesia of xylazine/ ketamine
mixture- 4.3–5 ml per rat (male, Wistar strain) for an average weight of 540–600 gms (80 mg/kg
body weight of ketamine and 8 mg/ kg body weight of xylazine in PBS). …
Combinations of dexmedetomidine and alfaxalone with butorphanol in cats: application of an innovative stepwise optimisation method to identify optimal clinical doses …
C Adami, T Imboden, AE Giovannini, C Spadavecchia – Journal of Feline Medicine …, 2015
… anaesthesia. Commonly used protocols often include an a 2 -adrenoreceptor agonist
to produce reliable sedation, an opioid derivative to provide some analgesia, and
ketamine owing to its anaesthetic and analgesic effects. …
[HTML] Development of Animal Models of Local Retinal DegenerationAnimal Models of Local Retinal Degeneration
H Lorach, J Kung, C Beier, Y Mandel, R Dalal, P Huie… – … Ophthalmology & Visual …, 2015
… Animal facility. For surgeries, animals (P35–P50) were anesthetized with ketamine
(75 mg/kg) and Xylazine (5 mg/kg), delivered by intramuscular injection. Subretinal
implantations were performed as previously described. 31 …
[HTML] Following specific podocyte injury captopril protects against progressive long term renal damage
YS Zhou, IA Ihmoda, RG Phelps, COS Bellamy… – F1000Research, 2015
… VD DOM02, made by Orion Pharma, supplied by Henry Schein Medical) and 100mg/ml
ketamine (Vetalar) (Ref. … Terminal blood samples were collected at week 8 from intraperitoneally
anaesthetised animals (injected with medetomidine and ketamine). …
Clinical Sedation Regimens
S Wilson – Oral Sedation for Dental Procedures in Children, 2015
Page 74. Clinical Sedation Regimens Stephen Wilson S. Wilson, DMD, MA, PhD
Division of Pediatric Dentistry, Department of Pediatrics, Cincinnati Children’s Hospital
Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 …
Electrocardiogram reference intervals for clinically normal wild-born chimpanzees (Pan troglodytes)
R Atencia, L Revuelta, JD Somauroo, RE Shave – American Journal of Veterinary …, 2015
… Immediately before the examination procedures, body weight was estimated.
Chimpanzees were anesthetized by administration of a combination of ketamine
hydrochloride a (5 mg/kg) and medetomidine b (50 μg/kg). Anesthetic …
Deep Sedation and GA
SI Ganzberg – Oral Sedation for Dental Procedures in Children, 2015
… When an anesthesia machine capable of delivering sevoflurane is not available, as is typical
is most dental offices,“induction” is most commonly provided with an intramuscular injection of
ketamine and midazolam with or without an anticholinergic, ie, such as glycopyr- rolate or …
Radiofrequency Ablation (RFA)
In-utero radiofrequency ablation in fetal piglets: lessons learned
OO Olutoye, AN Gay, F Sheikh, AC Akinkuotu… – Journal of Pediatric Surgery, 2015
Methods 90 day gestation Yorkshire piglets (term 115 days) were subjected to RFA of the
chest and abdominal viscera under various temperatures and wattages. The extent of tissue
damage was determined by NADPH diaphorase histochemistry. Results Tyne …
Strain echocardiographic assessment of left atrial function predicts recurrence of atrial fibrillation
SI Sarvari, KH Haugaa, TM Stokke, HZ Ansari, IS Leren… – Eur Heart J Cardiovasc …, 2015
… Of these, 30 had not while 31 had recurrence of AF after radiofrequency ablation (RFA). Twenty
healthy individuals were included for comparison. … For patients with symptomatic drug-refractory
AF, radiofrequency ablation (RFA) has become an important therapy option. …
[HTML] Current management of patients with hepatocellular carcinoma
T Kanda, S Ogasawara, T Chiba, Y Haga, M Omata… – World J Hepatol, 2015
… of HCC. Many HCC patients are treated with surgical resection and radiofrequency
ablation (RFA), although these modalities should be considered in only selected
cases with a certain HCC number and size. Although there …
PP. 26.17: OUR CLINICAL EXPERIENCE WITH COMBINATION THERAPY OF OLMISARTAN AND AMLODIPINE IN THE TREATMENT OF RESISTANT …
T Chakalaa-Yancheva, S Tisheva, A Qnakieva… – Journal of Hypertension, 2015
… In all patients MRA excluded new or progression of pre- existing low grade renal artery stenosis
as well as focal aneurysms at the sites of radiofrequency ablation. In none of the patients new
segmental perfusion deficits in either kidney were detected on MRI. …
Multiscale Tetrahedral Meshes for FEM Simulations of Esophageal Injury
LA Neves, E Pavarino, MP Souza, CR Valencio… – Computer-Based Medical …, 2015
… [3] OJ Eick and D. Bierbaum, “Tissue temperature- controlled radiofrequency ablation,” Pacing
and clinical electrophysiology, vol. … [4] MO Siegel, DM Parenti, and GL Simon, “Atrialesophageal
fistula after atrial radiofrequency catheter ablation,” Clinical infectious diseases, vol. …
The meaning of gross tumor type in the aspects of cytokeratin 19 expression and resection margin in patients with hepatocellular carcinoma
SC Gong, MY Cho, SW Lee, SH Kim, MY Kim, SK Baik – Journal of Gastroenterology …, 2015
… From March 2012 to December 2014, 87 patients with HCC underwent surgical treatment including
intraoperative radiofrequency ablation at Wonju Severance Christian Hospital, Wonju, Korea.
Among them, 75 patients who underwent only hepatectomy were enrolled in …
Impact of catheter ablation with remote magnetic navigation on procedural outcomes in patients with persistent and long-standing persistent atrial fibrillation
Q Jin, S Pehrson, PK Jacobsen, X Chen – Journal of Interventional Cardiac …, 2015
… venous anatomy, left atrial (LA) volume, procedure time, mapping plus ablation time,
radiofrequency (RF) abla … CFAEs at the right atrium were not mapped and ablated in this study.
Although PVAI and CFAE ablation time were calculat- ed separately, CFAE ablation time did …
The role of AEG-1 in the development of liver cancer
CL Robertson, J Srivastava, D Rajasekaran, R Gredler… – Hepatic Oncology, 2015
… by rapid growth and early vascular invasion and thus the incidence and mortality of the disease
run in parallel [1,3]. Standard treatment options for patients afflicted with localized forms of the
disease include surgical resection, radiofrequency ablation or liver transplantation [4–7 …
Unexpected Findings in the Left Atrium of a Patient with a Paravalvular Mitral Leak
FS Silva, CA Barreiros, MC Antunes, ÂL Nobre – Journal of Cardiothoracic and …, 2015
… described including catheter-based cardiac interventions (eg valvular procedures, coronary
intervention, radiofrequency ablation), endocarditis, myocardial infarction and blunt cardiac
trauma.1 There are also cases of spontaneous dissection 2,10-11 occurring in patients with …
[PDF] Typical chest pain and precordial leads ST-elevation in patients with pacemakers-are we always looking at an acute myocardial infarction?
MM Ostojić, TS Potpara, MM Polovina, MM Ostojić… – Vojnosanitetski pregled, 2015
… ECG changes occurred due to pericardial re- action following two interventions: pacemaker
implantation a month before and radiofrequency catheter ablation of AV junction two weeks
before presentation in Emergency De- partment. Conclusion. …
[PDF] AB10-06
RC ABLATION – Heart Rhythm, 2015
Methods: The clinical features including freedom from AF/atrial tachycardia (AT) recurrence
as outcome after RFCA were compared between women and men in 1: 1 age, AF type,
duration of AF (±1 year) matched manner. Subgroup analysis was performed in categories …
MULTI-POLE SYNCHRONOUS PULMONARY ARTERY RADIOFREQUENCY ABLATION CATHETER
S Chen – US Patent 20,150,201,988, 2015
Abstract: A multi-pole synchronous pulmonary artery radiofrequency ablation catheter may
comprise a control handle, a catheter body and an annular ring. One end of the catheter
body may be flexible, and the flexible end of the catheter body may be connected to the …
Diagnostic and Interventional Endoscopy
Y Tomizawa, I Waxman – Atlas of Esophageal Surgery, 2015
… previous ablation zone. Ablation is repeated until the entire length of disease has
received radiofrequency energy (Fig. 3.15). After the entire lesion is ablated, the
guidewire, ablation catheter, and endoscope are removed. For focal …
[HTML] Osteoid osteoma masquerading tubercular arthritis or osteomyelitis on MRI: Case series and review of literature
JP Singh, S Srivastava, D Singh – Indian Journal of Radiology and Imaging, 2015
… periostitis. The patient underwent CT-guided biopsy and radiofrequency ablation. The …
effusion. A CT-guided radiofrequency ablation (RFA) [Figure 10]C was performed and
the patient remained symptom-free at 20 months follow-up. Figure …
Hybrid Transthoracic Esophagectomy
B Borraez, MG Patti – Atlas of Esophageal Surgery, 2015
… hernia, 11, 12 Schatzki’s ring, 12, 13 sliding hiatal hernia, 10, 11, 46 squamous cell cancer, 19
Zenker’s diverticulum, 15, 97 Barrett’s esophagus esophagectomy, 151, 152 focal nodular lesion,
25, 27 proximal resection margin, 141, 147 radiofrequency ablation, 23, 29 salmon …
PP. 26.16: CAN AN HOSPITAL ADMISSION MODIFY THE COURSE OF PATIENTS WITH RESISTANT HYPERTENSION?.
J Ribeiro, A Correia, R Ferreira, P Morgado, JM Bastos… – Journal of Hypertension, 2015
… In all patients MRA excluded new or progression of pre- existing low grade renal artery stenosis
as well as focal aneurysms at the sites of radiofrequency ablation. In none of the patients new
segmental perfusion deficits in either kidney were detected on MRI. …
Perspectives on the modern management of non-valvularatrial fibrillation: non-valvular af
R Gopal, MH Tayebjee – SA Heart, 2015
… catheters and the development of balloon based or circular ablation catheters with multiple
ablation electrodes that can be applied to the pulmonary vein antrum to isolate pulmonary veins
and ablate left atrial substrate(44,17) (Figures 1 a,b,c). Both radiofrequency catheter and …
APPARATUS AND METHODS FOR CLOSING VESSELS
BB Hill, J Hong, W Qi – US Patent 20,150,201,947, 2015
… The following is a list of one or more advantages that may be achieved using the apparatus and
methods described herein, eg, as compared to endovenous laser, radiofrequency ablation
technologies, and other methods that destroy the vein by applying chemicals or applying …
Fluorescence Imaging Systems (PDE, HyperEye Medical System, and Prototypes in Japan)
T Ishizawa, N Kokudo – Fluorescence Imaging for Surgeons: Concepts and …, 2015
Hepatocellular Carcinoma Precursor Lesions
ML Smith – Surgical Pathology of Liver Tumors, 2015
Chronic Regional Pain Syndrome (CRPS/RSD)
A scoring rule-based truthful demand response mechanism
K Hara, T Ito – Computer and Information Science (ICIS), 2015 IEEE/ …, 2015
… Therefore, conventional scoring rule with single item, such as Brier score [5] is of no use for this
mode. In order to rightfully incentivize the CA to make their prediction of device shifting for multiple
items rightfully; the continuous ranked probability score (CRPS) is applied [13]. …
[PDF] Why Attackers Win: On the Learnability of XOR Arbiter PUFs
F Ganji, S Tajik, JP Seifert – 2015
… These attacks, as cost-effective approaches, can clone the challenge-response behavior of an
arbiter PUF by collecting a subset of challenge-response pairs (CRPs). … Moreover, when applying
current ML attacks, the maximum number of CRPs required for Page 3. …
[PDF] A Multivariate Modeling Approach for Generating Ensemble Climatology Forcing for Hydrologic Applications
S Khajehei – 2015
Page 1. Portland State University PDXScholar Dissertations and Theses Dissertations and Theses
Spring 7-21-2015 A Multivariate Modeling Approach for Generating Ensemble Climatology Forcing
for Hydrologic Applications Sepideh Khajehei Portland State University …
[HTML] Oil Palm Leaf and Corn Stalk–Mechanical Properties and Surface Characterization
Z Daud, MZM Hatta, H Awang – Procedia-Social and Behavioral Sciences, 2015
… Bhaduri et al., 1995; BK Bhaduri, A. Day, SB Mondal, .SK Sen; Ramie hemicelluloses as beater
additive in a paper making from jute-stick kraft pulp. Industrial Crps and Products, 4 (1995), pp.
79–84. Daud et al., 2013; Z. Daud, MZM Hatta, ASM Kassim, AM Aripin, H. Awang; …
[HTML] Nerve injury and neuropathic pain–a question of age
M Fitzgerald, R McKelvey – Experimental Neurology, 2015
… Furthermore several complex pain syndromes (eg CRPS) that emerge in older children are
associated with little or no measurable disease activity or inflammation at the time of presentation
and are clinically defined as ‘functional’ or ‘medically unexplained’ (Bromberg et al …
Acute acalculous cholecystitis and cardiovascular disease: a land of confusion
M Tana, C Tana, G Cocco, G Iannetti, M Romano… – Journal of Ultrasound, 2015
… Most common clinical onset was represented by fever (70 %) in opposite to abdominal pain
which occurred in 20 % of patients. 8/10 patients were male. Elevated CRPs, leukocytosis
(60 %), and elevated aminotransferase (30 %) occurred frequently. …
[PDF] Characterizing the Stability of Okun’s Law during Economic Recessions by cross-Recurrence Plot and Rolling Regression
J Gao, Y Cao
… 2 n xx x , , , and 1 2 n yy y , , , , which, for concreteness, may be equated to unemployment and
production data, one obtains CRPs (Marwan & Kurths 2002; Marwan, et al. 2007). … 4, No. 3 ~ 5 ~
Figure 2. Cross recurrence plots (CRPs); notice the correspondence of vertical …
[PDF] Use of Hidden Markov Mobility Model for Location Prediction and Biclustering for Cache Replacement in MANET
BD Shelar, MDK Chitre
… But these policies give satisfactory performance for stable user and prove inefficient for mobile
user which free to change his direction. Direction and Distance Based CRPs think for the mobile
nature of user. … Prediction Based CRPs analyze the history of users’ movements. …
Field Deployable Chemical Redox Probe for Quantitative Characterization of Carboxymethylcellulose Modified Nano Zerovalent Iron
D Fan, S Chen, RL Johnson, PG Tratnyek – 2015
Page 1. 1 2 Field Deployable Chemical Redox Probe for Quantitative Characterization of 3
Carboxymethylcellulose Modified Nano Zerovalent Iron 4 5 6 Dimin Fan, Shengwen Chen, Richard
L. Johnson, and Paul G. Tratnyek* 7 8 Institute of Environmental Health 9 …
Technical innovations for small-scale producers and households to process wet cassava peels into high quality animal feed ingredients and aflasafe™ substrate
I Okike, A Samireddypalle, L Kaptoge, C Fauquet… – Food Chain, 2015
Headache and Pain
R Baron, A May – 2015
Molecular Biology of Retinoblastoma
SD Walter, JW Harbour – Recent Advances in Retinoblastoma Treatment, 2015
… Rb directly inhibits E2Fs by binding and masking the transactivation domain, and it also recruits
chromatin remodeling proteins (CRPs) that alter local chromatin structure into a confirmation
that is not permis- sive for transcription.(b) When Rb is hyperphosphory- lated, it does …
[PDF] Guidelines for Neuromusculoskeletal Infrared Thermography Sympathetic Skin Response (SSR) Studies
DO Getson, S Govindan, J Uricchio, T Bernton…
… Assessment of patients with presumptive Complex Regional Pain Syndrome (CRPS) Type I or
II – formally known as Reflex Sympathetic Dystrophy (RSD), Thoracic Outlet Syndrome,
Vaso-motor Headache and Barre’-Leiou Syndrome. … CRPS: Current Diagnosis and Therapy. …
[HTML] Thread: Advances in treatment of post-amputation phantom limb pain
W Young, J Date
… reviewed fifteen papers reporting mirror therapy to treat upper limb function and concluded that
most of the studies were weak methodologically and that the results suggest possible benefit
in patients after stroke and complex regional pain syndrome (CRPS) but the …
[PDF] Guidelines For Dental-Oral And Systemic Health Infrared Thermography
M Brioschi, H Usuki, BSN Jan Crawford, P Steed…
… c. Relevant risk factors for inflammation or vasomotor instability: prior history of RSD
or CRPS, trauma, fracture, repetitive use, vibration syndrome, peripheral neuropathy,
spinal pathology, radiculopathy, vasomotor headache, Page 4. …
[HTML] Chronic Pain Medication & Treatment Guide
AR Guide
… cord injuries. It may develop months or years after injury or damage to the CNS.
This also includes conditions such as chronic headaches, fibromyalgia, and Complex
Regional Pain Syndrome (CRPS). Tailoring selection of …
[DOC] WORKSHOP ON BEST PRACTICE METHODS FOR ASSESSING THE IMPACT OF POLICY ORIENTED RESEARCH SUMMARY AND RECOMMENDATIONS FOR …
F Place, P Hazell
WORKSHOP ON BEST PRACTICE METHODS FOR ASSESSING THE IMPACT OF
POLICY ORIENTED RESEARCH. SUMMARY AND RECOMMENDATIONS FOR
THE CGIAR. Frank Place and Peter Hazell. WORKSHOP ON …
CRPS A contingent hypothesis with prostaglandins as crucial conversion factor
PHE van der Veen – Medical Hypotheses, 2015
Abstract CRPS is an acute pain disease expressed as chronic pain with a severe loss of
tissue and function. CRPS usually occurs after minor injuries and then progresses in a way
that is scarcely controllable, or completely uncontrollable. This article addresses the …
Vitamin C to Prevent Complex Regional Pain Syndrome in Patients With Distal Radius Fractures: A Meta-Analysis of Randomized Controlled Trials
N Evaniew, C McCarthy, YV Kleinlugtenbelt, M Ghert… – Journal of orthopaedic …, 2015
… Collapse Box Abstract. Objective: To determine whether vitamin C is effective in preventing
complex regional pain syndrome (CRPS) in patients with distal radius fractures. … 2 CRPS has been
previously referred to as causalgia, reflex sympathetic dystrophy, and algodystrophy. 3. …
Injury of the corticoreticular pathway in patients with mild traumatic brain injury: A diffusion tensor tractography study
HD Lee, SH Jang – Brain Injury, 2015
… Figure 1. Diffusion tensor tractography for the corticoreticular pathway (CRP): a normal control
subject (44 year-old, female), type A = the CRPs showed narrowing, although integrity was
preserved from the premotor cortex to the reticular formation of the medulla, type B = the …
[PDF] Plasma Exchange Therapy in Patients with Complex Regional Pain Syndrome
E Aradillas, RJ Schwartzman, JR Grothusen, A Goebel – Pain Physician, 2015
Page 1. Background: Complex regional pain syndrome (CRPS) is a severe chronic
pain condition that most often develops following trauma. … These patients were then
placed on Complex regional pain syndrome (CRPS) is a …
Controversial Pain Syndromes of the Arm: Pathogenesis and Surgical Treatment of Resistant Cases
A Wilhelm – 2015
[PDF] Mixture EMOS model for calibrating ensemble forecasts of wind speed
S Baran, S Lerch – arXiv preprint arXiv:1507.06517, 2015
… The most popular scoring rules are the logarithmic score, that is the negative logarithm of the
predictive PDF evaluated at the verifying observation and the continuous ranked probability score
(CRPS; Gneiting and Raftery, 2007; Wilks, 2011). … CRPS(F, x) := ∫ ∞ …
[PDF] Targeted Ultrasound-Guided Double Catheters (Infraclavicular-Brachial Plexus, Median Nerve) Facilitate Hand Rehabilitation with Superb Analgesia and Motor …
AE Holman, B Sharma, VE Modest – Open Journal of Anesthesiology, 2015
… http://creativecommons.org/licenses/by/4.0/ Abstract A 44-year-old male who suffered a
crush-degloving hand injury complicated by Complex Regional Pain Syndrome (CRPS) type
I was scheduled for operative hand manipulation and inpatient physi- otherapy. …
Leads for neurostimulation and methods of assembling same
A Raines – US Patent 9,084,882, 2015
… As used herein the term “complex regional pain syndrome” or “CRPS” refers to painful
conditions that usually affect the distal part of an upper or lower extremity and are
associated with characteristic clinical phenomena. CRPS …
[PDF] Identification and characterization of a novel family of cysteine-rich peptides (MgCRP-I) from Mytilus galloprovincialis
M Gerdol, N Puillandre, G De Moro, C Guarnaccia… – Genome Biology and …, 2015
… encoding peptides with unique chemico-physical properties and/or sequence patterns. Actually,
cysteine-rich peptides (CRPs) encompass a large and widespread group of secreted … plants
(Gruber, et al. 2007; Marshall, et al. 2011; Taylor, et al. 2008). Invertebrate CRPs are …
Peri‐infarct reorganization of an injured corticoreticulospinal tract in a patient with cerebral infarct
SH Jang, J Lee, HD Lee – International Journal of Stroke, 2015
… (c) The CRPs are descended through the subcortical white matter in two age-matched normal
control subjects. Letter to the editor © 2015 World Stroke Organization E62 Vol 10, August 2015,
E62–E63 Page 2. References 1 Yeo SS, Chang MC, Kwon YH, Jung YJ, Jang SH. …
Fibromyalgia
Depressive-like symptoms in a reserpine-induced model of fibromyalgia in rats
A Blasco-Serra, F Escrihuela-Vidal, EM González-Soler… – Physiology & Behavior, 2015
Abstract Since the pathogenesis of fibromyalgia is unknown, treatment options are limited,
ineffective and in fact based on symptom relief. A recently proposed rat model of
fibromyalgia is based on central depletion of monamines caused by reserpine …
Is there any link between joint hypermobility and mitral valve prolapse in patients with fibromyalgia syndrome?
E Kozanoglu, IC Benlidayi, RE Akilli, A Tasal – Clinical Rheumatology, 2015
Abstract The objective of the present study is to determine whether benign joint
hypermobility syndrome (BJHS) modifies the risk of mitral valve prolapse (MVP) in patients
with fibromyalgia (FM). Female patients fulfilling the 1990 American College of …
[HTML] Calibration and Validation of the Dutch-Flemish PROMIS Pain Interference Item Bank in Patients with Chronic Pain
MHP Crins, LD Roorda, N Smits, HCW de Vet… – PLOS ONE, 2015
… as pain that persists beyond the normal tissue healing time, in which the most prevalent pain
is musculoskeletal pain, with prevalence varying from 30–40% for low back pain, 15–20% for
shoulder- and neck pain, 10–15% for chronic widespread pain and 2% for fibromyalgia [3,4 …
Assessment of response bias in neurocognitive evaluations
DA Carone – NeuroRehabilitation, 2015
… survey data of neuropsychologists show that the base rates of malingering or symptom
exaggeration are much higher (29% to 41%) in settings where patients are seeking financial
compensation or disability and in patient groups (ie, concussion, fibromyalgia, chronic fatigue …
[PDF] SENSE OF WELL-BEING IN PATIENTS WITH FIBROMYALGIA. AEROBIC EXERCISE PROGRAM IN A MATURE FOREST: A PILOT STUDY
S Lopez-Pousa, GB Pagès, S Monserrat-Vila
ABSTRACT Background and objective: Most patients with fibromyalgia benefit from different
forms of physical exercise. Studies show that exercise can help restore the body’s
neurochemical balance and that it triggers a positive emotional state. So, regular exercise …
[HTML] Miller Chiropractic & Laser Treatment Center
D Emery
… Acta Medica Academica 2013;42(1):46-54. doi: 10.5644/ama2006-124.70. Study Finds
Chiropractic Beneficial for Fibromyalgia. A new study from Egypt reports that chiropractic care
can be an effective treatment strategy for fibromyalgia treatment with chiropractic care. …
[PDF] Cost-effectiveness of 40-hour versus 100-hour vocational rehabilitation on work participation for workers on sick leave due to subacute or chronic musculoskeletal …
TT Beemster, JM van Velzen, CAM van Bennekom… – Trials, 2015
… as follows: 1) individuals of working age (18 to 65 years); 2) suffering from subacute (6 to 12 weeks)
or chronic (>12 weeks) nonspecific musculoskeletal pain such as back, neck, shoulder,
widespread pain, Whiplash Associated Disorder (WAD I or II), or fibromyalgia; 3) having …
Peer-Reviewed Abstracts
D Avans – Research Quarterly for Exercise and Sport, 2015
… Fine motor control knowingly declines with age and certain diseases such as fibromyalgia and
cerebral palsy (Perez-de-Heredia-Torres, 2013). … Research of this nature could also be translated
to diseased populations such as those with fibromyalgia or diabetes. …
Gastro-protective and Anti-stress Efficacies of Monomethyl Fumarate and a Fumaria indica Extract in Chronically Stressed Rats
A Shakya, UK Soni, G Rai, SS Chatterjee, V Kumar – Cellular and Molecular …, 2015
… are some of the major symptoms of numerous, if not all, chronic inflammatory diseases
accompanying central sensitivity syndromes (Yunus 2008 ), and it is now well recognized that
cytokine and immune system abnormalities are the root cause of fibromyalgia and other central …
[PDF] Mechanisms of action of balneotherapy in rheumatic diseases
A Fioravanti, S Cheleschi – IV CIBAP BOÍ 2015
… Anti-inflammatory aspects Recent studies have shown a reduction of circulating levels of
Prostaglandin E2 (PGE2) and Leukotriene B4 (LTB4), important mediators of inflammation and
pain, in patients suffering from OA or fibromyalgia who undergo mud-packs or …
Determinants of Patient Satisfaction in an Academic Rheumatology Practice.
JH Ku, A Danve, H Pang, D Choi, JT Rosenbaum – Journal of clinical rheumatology: …, 2015
… 95% CI, -15.25 to -3.25), arthralgia (β = -8.67; 95% CI, -16.60 to -0.74), myalgia (β = -8.67; 95%
CI, -16.60 to -0.74), gout (β = -7.5; 95% CI, -14.13 to -0.89), ankylosing spondylitis (β = -5.20;
95% CI, -9.65 to -0.75), pain (β = -4.62; 95% CI, -8.43 to -0.81), fibromyalgia (β = -4.62; 95 …
Method and Apparatus for Diagnosing and Assessing Centralized Pain
JB Hargrove – US Patent 20,150,201,879, 2015
… Because of this emerging understanding, the role of CS is increasingly being shown to be
pathological in seemingly unrelated chronic pain conditions and syndromes including fibromyalgia,
complex regional pain syndrome, phantom pain, and migraine headaches. …
FATTY ACID DERIVATIVES FOR USE IN A METHOD OF TREATING DEPRESSION AND ASSOCIATED CONDITIONS
E Berry, Y Avraham, J Katzhendler, J Mograbi… – US Patent 20,150,202,179, 2015
… Abstract: The invention provides fatty acid derivatives for use in a method of treatment of at least
one disease, disorder or condition selected from anxiety, depression, conditions associated
menopause, stress, bipolar disorder, neuropathic pain and fibromyalgia. …
ANTIBODIES TO IL-6 AND THEIR USES
A Rajpal, MN Devalaraja, K Toy, L Yang, H Huang… – US Patent 20,150,203,574, 2015
… The term “fibromyalgia” is also known as fibromyalgia syndrome. The American College
of Rheumatology (ACR) 1990 classification criteria for fibromyalgia include a history
of chronic, widespread pain for more than three months …
Impact of Gender-Based Aggression on Women’s Mental Health in Portugal
M Reis, L Ramiro, MG de Matos – … Mental Health: Resistance and Resilience in …, 2015
… The rate was even higher for women who had experienced non-partner sexual violence (WHO,
2013). Health effects can also include headaches, back pain, abdominal pain, fibromyalgia,
gastrointestinal disorders, limited mobility, and poor overall health (WHO, 2013). …
Pain 2014 Refresher Courses: 15th World Congress on Pain
SN Raja, CL Sommer – 2015
Restless Legs Syndrome: The Devil Is in the Details
PJ Sampognaro, RE Salas, A Kalloo, C Gamaldo – Sleepy or Sleepless: Clinical …, 2015
… medical conditions Restless legs syndrome (Willis-Ekbom disease) Renal failure Periodic limb
movement disorder Anemia REM sleep behavior disorder (RBD) Peripheral neuropathy
Obstructive sleep apnea syndrome (OSAS) Rheumatoid arthritis Fibromyalgia Attention deficit …
[PDF] Dermatologic Extrahepatic Manifestations of Hepatitis C
B Dedania, GY Wu – Journal of Clinical and Translational Hepatology, 2015
… cutanea tarda23 – Lichen planus33,35,36 – Sicca syndrome – Auto-antibody productions
(rheumatoid factor, cryoglobulins, anti-smooth muscle) – Glomerulonephritis12 C. Possible
association2,16 – Polyarthritis – Pruritus – Fibromyalgia – Chronic polyradiculoneuropathy – Lung …
PHOSPHATIDYLINOSITOL-3-KINASE C2 BETA MODULATORS AND METHODS OF USE THEREOF
E Skolnik, Z Li, S Srivastava – US Patent 20,150,204,846, 2015
… Exemplary IgE-mediated allergic disorders include, without limitation, allergic rhinitis,
allergic or atopic asthma, anaphylaxis, atopic dermatitis, eczema, hay fever,
fibromyalgia, and an immediate type hypersensitivity reaction. …
Psychological Interventions for the Management of Chronic Pain: a Review of Current Evidence
RS Kaiser, M Mooreville, K Kannan – Current Pain and Headache Reports, 2015
… A few of the many variants of this approach will be highlighted. Currently, cognitive
behavioral therapy (CBT) is a first-line psychological treatment for individuals with chronic
pain, such as back pain, headache, arthritis, and fibromyalgia [ 12 •]. …
