by admin | Jul 17, 2015 | Uncategorized
Ketamine Combination Regimen Shows Promise For Long-term CRPS-1 Relief
Experts expect further refinement of treatment protocols for pain syndrome
by Gabriel Miller
Over the past 10 years, ketamine has emerged as a viable and potent treatment for patients with refractory complex regional pain syndrome type 1. In a new study, investigators show that combining epidural analgesia with inpatient ketamine infusion, followed by outpatient ketamine “boosters,” is an effective therapeutic protocol for this difficult-to-treat disease.
Ketamine was recognized as a potential treatment for complex regional pain syndrome type 1 (CRPS-1) in the United States approximately eight years ago. Since that time, two modalities have emerged: an “awake technique” in which subanesthetic ketamine is continuously infused, and a more dramatic protocol in which patients receive extremely high doses of ketamine while in a medically induced coma.
The high-dose method is currently not practiced in the United States, but a select group of centers has been using ketamine and studying the subanesthetic approach.
Advocates of ketamine for CRPS-1, previously known as reflex sympathetic dystrophy (RSD), say that the ketamine protocols first “turn off the pain” and then “reset the whole system” of pain transmission.
CRPS-1 appears to be caused by central sensitization and pain “wind-up,” a gradual, cumulative hyper-excitable neuronal response resulting from repeated painful stimulation of peripheral nerves. The N-methyl-d-aspartate (NMDA) receptor complex appears to play a major role in the development of this overall central sensitization; additionally, evidence shows that NMDA receptors are present in the peripheral nerves.
“Pain begets more pain,” said Robert Schwartzman, MD, professor and chairman of the Department of Neurology at Drexel University in Philadelphia. “When NMDA receptors are open, calcium enters the pain transmission neuron and initiates cascades that end up making pain transmission neurons more easily fired. This calcium entry causes something akin to long-term potentiation—it makes those cells more excitable—and that’s clearly one of the mechanisms in at least 80% of RSD patients.”
NMDA receptor antagonists, such as ketamine, have long been thought to be a viable treatment for both chronic pain conditions in general and CRPS-1 in particular.
“What [an NMDA receptor antagonist] does is block that mechanism of calcium entry into cells; once you’ve turned this system off, you’ve turned off the genetic transformation that occurs with persistent pain,” said Dr. Schwartzman, who has treated more than 500 patients with CRPS-1 using ketamine. “We are tuning back the hypersensitivity in the pain transmission neurons that is caused by pain.”
But psychomimetic effects, including hallucinations or paranoid delusions, and central nervous system (CNS) side effects have previously limited the therapeutic impact of the strongest-acting NMDA receptor antagonists, such as ketamine.
What’s more, in order to prevent the rapid re-sensitization of the CNS, the primary source of pain must also be controlled. Before beginning ketamine therapy for CRPS-1, a patient’s initial source of chronic pain, such as an improperly healed fracture, a neuroma or pressure on a nerve, must be identified and treated.
Thus, a typical ketamine protocol for CRPS-1 requires first treating any primary sources of pain, and then following with five to 10 days of inpatient low-dose, continuous ketamine infusion coupled with a high-dose benzodiazepine to minimize CNS side effects.
Finally, despite exceptional initial results—in prospective trials, between 80% and 100% of patients refractory to pharmacologic treatment for CRPS-1 report significant relief with ketamine—the treatment effect fades over time. To compensate, clinicians have now been using outpatient ketamine “boosters” in an attempt to extend the initial treatment effect.
Innovative Protocol
The current study is unique in that it also adds an additional epidural anesthetic during ketamine infusion, concomitantly blocking pain while the NMDA receptor complex is “reset” with ketamine. The new research was presented by lead study author Hai Nguyen, MD, an anethesiologist in Cleveland, Ohio, at the annual meeting of the American Society of Regional Anesthesia and Pain Medicine (ASRA) in San Antonio (abstract ID: 9).
Patients received a five-day inpatient, continuous IV ketamine infusion (0.6-0.8 mg/kg per hour; maximum, 60 mg/h) combined with continuous epidural analgesia (bupivacaine, dilaudid and clonidine) as well as 1 mg lorazepam every six hours. Patients were then given an outpatient, IV ketamine “booster” of 100 to 250 mg combined with 2 mg midazolam every two to four weeks for two months. The booster was given over a four-hour period on two consecutive days.
Forty-two patients were studied, and prior to ketamine treatment, 92.9% (39 of 42) had CRPS-1 involvement in all four extremities, 95.2% (40 of 42) experienced pain affecting the entire body and 100% had a numeric pain scale (NPS) rating of 10 on a 10-point scale.
At 12 weeks, 61.9% of patients reported moderate pain improvement, defined as a decrease of three or more points on the NPS. At 24 weeks, 30.9% reported continued moderate pain relief.
“The novel element [of the study] is combining the epidural component,” said Michael Goldberg, MD, professor and chief of anesthesiology at Cooper University Hospital in Camden, N.J., who uses continuous brachial plexus blocks as a peripheral anesthetic during his ketamine treatments.
“But the interesting thing to notice with this study, and all of our studies, [is that] we find that at about 12 weeks we have less significant pain relief. So it doesn’t stick and that’s the problem with the ketamine treatment for all of us,” Dr. Goldberg said.
With the somewhat complex interaction of drugs, side effects can be significant in ketamine protocols, particularly in the patients receiving moderate doses. These patients require more ketamine to control their CRPS-1 but not enough to necessitate a dose that requires deep sedation, Dr. Goldberg said.
In the 42 patients studied, significant side effects included nausea (64.3%), vomiting (38.1%), mild liver function test elevation (4.8%) and delirium (2.4%).
Overall, side effect risks associated with ketamine therapy have been overinflated, said Dr. Schwartzman, and in a population of patients with completely debilitating refractory pain, the risk for severe side effects is justified.
“[Side effects] have been grossly overexaggerated in the literature,” said Dr. Schwartzman. “Even in this study they didn’t use enough midazolam, but when you use [ketamine] properly, it’s a very safe drug. We’ve done it thousands of times.” Randomized controlled trials have further confirmed the efficacy and safety of ketamine therapy, said Dr. Schwartzman, who authored one such study (Pain 2009;147:107-115).
Anecdotally, he said, patients are willing to put up with side effects, even at a cost of as much as $10,000 for a treatment cycle.
“Insurance companies don’t pay for this,” he said. “When Americans are paying for stuff out of pocket, you know it has to work.”
by admin | Jul 7, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Withdrawal from Acute Amphetamine Induces an Amygdala-Driven Attenuation of Dopamine Neuron Activity: Reversal by Ketamine.
P Belujon, NL Jakobowski, HK Dollish, AA Grace – … : official publication of the …, 2015
Drug addiction is a chronic disorder characterized by a cycle composed of drug seeking,
intoxication with drug taking and withdrawal associated with negative affect. Numerous
studies have examined withdrawal/negative affect after chronic use; however, very few …
Enantioselective inhibition of D‐serine transport by (S)‐ketamine
NS Singh, M Bernier, S Camandola, MA Khadeer… – British Journal of …, 2015
Background and purpose Patients with major depressive disorder receiving racemic
ketamine,(R, S)-ketamine, experience transient increases in Clinician-Administered
Dissociative States Scale (CADDS) scores and coincident drop in plasma D-serine levels. …
Pain Management with Low-Dose Ketamine Infusions
A Katz – Emergency Medicine News, 2015
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. … The M 2 E Too! Blog by Larry Mellick, …
Sedative medications outside the operating room and the pharmacology of sedatives
TG Hansen – Current Opinion in Anesthesiology, 2015
… Ketamine. Ketamine is a unique phencyclidine derivate that differs from other sedatives in several
ways. … Ketamine seems to induce a dissociative anesthetic state with functional and
electrophysiological separation between the limbic system and hypothalamus. …
Pre-Emptive Analgesia with Ketamine for Relief of Postoperative Pain After Surgical Removal of Impacted Mandibular Third Molars
A Hadhimane, M Shankariah, KV Neswi – Journal of Maxillofacial and Oral Surgery, 2015
Purpose In this study we assessed the clinical efficacy of sub-mucosal injection of ketamine
at sub-anesthetic dose of 0.5 mg/kg on post-operative pain, swelling and trismus following
surgical extraction of impacted mandibular third molars. Methods Forty bilaterally …
Fluorescence‐guided surgery of human prostate cancer experimental bone metastasis in nude mice using anti‐CEA dylight 650 for tumor illumination
S Miwa, N De Magalhães, M Toneri, Y Zhang, W Cao… – Journal of Orthopaedic …, 2015
… Tumor implantation Six to eight-week-old male mice were anesthetized by a ketamine mixture
(10 µL ketamine HCL, 7.6 … Before resection of the metastatic tumor, mice were anesthetized with
the ketamine mixture (described above), and their limbs were sterilized with alcohol. …
Reassessment of the antioxidative mixture for the challenging electrochemical determination of dopamine, noradrenaline and serotonin in microdialysis samples
J Van Schoors, C Lens, K Maes, Y Michotte, I Smolders… – Journal of Chromatography …, 2015
… Diazepam 10 mg/2 mL is purchased as Valium ® from Roche (Cenexi, Fontenay-sous-Bois,
France), ketamine 1000 mg/10 mL as Ketamine 1000 ® from Ceva (Libourne, France), Ketoprofen
1% as Ketofen ® from Merial (Toulouse, France) and NaCl 0.9% from Baxter (Lessines …
Ultrasound-induced suppression of visually-evoked potentials: experience in nonhuman primates with a clinical transcranial MRI-guided focused ultrasound system
N McDannold, C Arvanitis, N Vykhodtseva… – Journal of Therapeutic …, 2015
… 650 kHz. Methods. The animal was deeply anesthetized using ketamine and
dexdormitor. First we targeted the LGN using MR temperature imaging, and then
we relocated the MRI table just outside the MRI. Visually-evoked …
Severe Acquired Idiopathic Thrombocytopenia in a Female Cynomolgus Macaque (Macaca fascicularis)
CM Parrula, J Mysore, H Burr, W Freebern, N Neef – Comparative Medicine, 2015
… On day 4, a follow-up complete physical exam under ketamine sedation (10 mg/kg IM; ketamine
hydrochloride, Fort Dodge Animal Health, Fort Dodge, IA), showed diffuse, pale-red discoloration
in both inguinal regions, as noted previously, and multifocal pinpoint foci of …
Estradiol protects female rats against sepsis induced by Enterococcus faecalis improving leukocyte bactericidal activity
RS Saia, FM Garcia, EC Cárnio – Steroids, 2015
… 0.5–1 × 10 10 CFU/animal) (time “zero” hour). At 6 and 24 h, rats were deeply
anesthetized (ketamine and xylazine at 55 and 10 mg/kg, respectively, ip) for sample
collection. As detailed in the subsequent sections, the blood …
Hot Off the Press: Subdissociative‐dose Ketamine for Acute Pain in the Emergency Department
AB Drake, WK Milne, CR Carpenter – Academic Emergency Medicine, 2015
… Social Media. Hot Off the Press: Subdissociative-dose Ketamine for Acute Pain in the Emergency
Department. … How to Cite. Drake, AB, Milne, WK, Carpenter, CR (2015), Hot Off the Press:
Subdissociative-dose Ketamine for Acute Pain in the Emergency Department. …
Optimization and application of an extraction procedure to determine drugs of abuse in solid environmental matrices of Turia River Basin
MJ Andres, R Alvarez, V Andreu, Y Pico – EGU General Assembly Conference …, 2015
… Amphetamine, methamphetamine, ethylamphetamine, ecstasy, ethylone, bk-MMBDB and MBDB
belong to phenylethylamine group; codeine and ketamine belong to opioid and phencyclidine
group, respectively, and benzoylecgonine is the major excreted metabolite of the …
Green spaces and cognitive growth in children
C Dieme – PNAS, 2015
… AG. Previous Section. Neural mechanism of ketamine. … Ketamine can produce rapid and
long-lasting antidepressant effects, but the drug’s potential for side effects and abuse limits its
widespread use, and the cellular mechanisms of ketamine’s effects are not yet known. …
Increasing use of ‘party drugs’ in people living with HIV on antiretrovirals: a concern for patient safety
M Bracchi, D Stuart, R Castles, S Khoo, D Back… – AIDS, 2015
… These substances are a combination of ‘club drugs’ (methylenedioxy- methamphetamine,
gamma-hydroxybutyrate, ketamine, benzodiazepine) and drugs that are more specifically used
in a sexualized context (methamphetamine, mephe- drone, poppers and erectile … Ketamine …
Halothane Modulates the Type I Interferon Response to Influenza and Minimizes the Risk of Secondary Bacterial Pneumonia through Maintenance of Neutrophil …
BA MacDonald, KV Chakravarthy, BA Davidson… – Anesthesiology, 2015
… The authors demonstrate that halothane mitigates the risk of SBP postflu through modulation
of the effects of type I interferon (IFN). METHODS: Mice (n = 6 to 15) were exposed to halothane
or ketamine and treated with influenza and Streptococcus pneumoniae. …
[HTML]Airtraq® laryngoscope-assisted fiberoptic bronchoscope intubation in a child with Pierre-Robin sequence: a case report
S Zhang, M Yi – International Journal of Clinical and Experimental …, 2015
… Sedation was achieved with IV dexmedetomidine 1 μg/kg and ketamine 1 mg/kg. … We
opted to use dexmedetomidine and ketamine in this child because they provide
sedation and analgesia without compromising respiratory drive. …
[HTML]Transcutaneous electric acupoint stimulation alleviates remifentanil-induced hyperalgesia in patients undergoing thyroidectomy: a randomized controlled trial
Y Chen, Y Yao, Y Wu, D Dai, Q Zhao, L Qiu – International Journal of Clinical and …, 2015
… Some medications, including ketamine, methadone, dextromethorphan, COX-2 inhibitors and
α 2 receptor agonists can modulate remifentanil-induced hyperalgesia [7]. Due to drug-related
side effects and longer duration of PACU stay, however, we have found these …
Impact of Obesity on Endotoxin-Induced Disseminated Intravascular Coagulation.
T Duburcq, A Tournoys, G Viviane, T Hubert, V Gmyr… – Shock, 2015
… animals). For the experiment, animals were premedicated with intramuscular injection of ketamine
(Ketamine 1000, 10 mg/kg of body weight; Virbac, Carros, France) and xylazine (Sedaxylan,
2.5 mg/kg of body weight; CEVA Santé Animale, Libourne, France). Then we …
Endocannabinoid signaling mechanisms in the substantia nigra pars reticulata modulate GABAergic nigrotectal pathways in mice threatened by urutu-cruzeiro …
RC Almada, CM Roncon, DH Elias-Filho, NC Coimbra – Neuroscience, 2015
… The surgeries were performed under deep anesthesia with 100 mg/kg ketamine (Ketamine
Agener, União Química Farmacêutica Nacional, São Paulo, Brazil) and 10 mg/kg xylazine
(Calmiun, União Química Farmacêutica Nacional, São Paulo, Brazil). …
ACUTE INHIBITION OF MONOAMINE OXIDASE AND ISCHEMIC PRECONDITIONING IN ISOLATED RAT HEARTS: INTERFERENCE WITH POSTISCHEMIC …
MD Dănilă, AI Privistirescu, SN Mirica, A Sturza… – Canadian Journal of …, 2015
… Male (body weight 400-450 g) and female (body weight 250-300 g) Wistar rats were anesthetized
with ketamine (Vetased, 30 mg/kg) and xylazine (Xylazin, 10 mg/kg) … Page 4 of 23 Page 5. 5
ketamine able to induce anesthesia was chosen in order to not interfere with the IPC- …
Radiofrequency Ablation (RFA)
In vitro artefact assessment of a new MR-compatible microwave antenna and a standard MR-compatible radiofrequency ablation electrode for tumour ablation
R Hoffmann, H Rempp, F Eibofner, DE Keßler… – European Radiology, 2015
Objective To evaluate and compare artefact configuration and diameters in a magnetic
resonance (MR)-compatible prototype microwave (MW) applicator and a standard MR-
compatible radiofrequency (RF) applicator for MR-guided tumour ablation. Methods Both …
Does Surgical Resection Provide Better Outcomes Than Radiofrequency Ablation in Patients With BCLC Very Early-stage Hepatocellular Carcinoma?.
C Li, TF Wen – Annals of Surgery, 2015
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. … Skip Navigation Links Home > …
Comparing outcome of radiofrequency ablation in Barrett’s with high grade dysplasia and intramucosal carcinoma: a prospective multicenter UK registry.
RJ Haidry, G Lipman, MR Banks, MA Butt, V Sehgal… – Endoscopy, 2015
Background and study aim: Mucosal neoplasia arising in Barrett’s esophagus can be
successfully treated with endoscopic mucosal resection (EMR) followed by radiofrequency
ablation (RFA). The aim of the study was to compare clinical outcomes of patients with …
Effectiveness of focal vs. balloon radiofrequency ablation devices in the treatment of Barrett’s esophagus
J Brown, B Alsop, N Gupta, DC Buckles, MS Olyaee… – United European …, 2015
Abstract Background and aims The safety and efficacy of radiofrequency ablation (RFA) in
treatment of Barrett’s esophagus (BE)-associated dysplasia has been well established. The
effectiveness of focal and balloon RFA devices has not been compared. Therefore, the …
Microwave Ablation: Comparison of Simultaneous and Sequential Activation of Multiple Antennas in Liver Model Systems
CM Harari, M Magagna, M Bedoya, FT Lee Jr… – Radiology, 2015
… Although both methods have been used in clinical studies of radiofrequency (RF) and microwave
ablation, an optimal delivery method has not yet been determined (6–9). Comparison studies
of sequential and simultaneous RF ablation techniques have concluded that …
Heparin Kinetics: The “Holy Grail” of Periprocedural Anticoagulation for ablation of atrial fibrillation
DF Briceno, A Natale, LD Biase – Pacing and Clinical Electrophysiology, 2015
… anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from
a multicenter prospective registry. … anticoagulation in patients undergoing radiofrequency ablation
for atrial fibrillation: results from a multicenter prospective registry. …
Catheter Ablation of Atrial Fibrillation Should Be Offered as Primary Therapy: What’s Your Hurry?
EF Wedam, MCP Haigney – Cardiac Electrophysiology Clinics, 2015
… medications. Radiofrequency ablation/cryoballoon ablation: a cure for atrial fibrillation?
Merriam-Webster’s … unknown. Does early radiofrequency ablation/cryoballoon ablation
prevent progression to permanent atrial fibrillation? A major …
OC-037 6 year disease durability outcomes on patients treated with endoscopic therapy for barrett’s related neoplasia from the uk registry
R Haidry, G Lipman, A Gupta, J Dunn, H Smart… – Gut, 2015
… Introduction Endoscopic therapy with combined Endoscopic mucosal resection (EMR) followed
by Radiofrequency ablation (RFA) is now the recommended first line … Thereafter patients underwent
RFA 3 monthly until all visible BE was ablated or cancer developed (endpoints). …
[HTML]Hybrid atrial fibrillation ablations and the increasing importance of the hybrid cardiovascular laboratory operating room
WJ Schleifer, JF Beshai, H Ramakrishna – Annals of Cardiac Anaesthesia, 2015
… the epicardium. [4] Moreover, endocardial catheters can check for the completeness
of the epicardial lesions and potentially identify gaps, which can then be addressed
with endocardial radiofrequency ablation. A similar approach …
[PDF]Effects of Hepatitis B Virus Load on Hepatectomy
M Wang, W Peng, TF Wen, LH He, C Li – Clin Microbiol, 2015
… MC: Milan Criteria; HR: Hepatic Resection; AFP: Alpha-Fetoprotein; OS: Overall Survival; RFS:
Recurrence-Free Survival; DNA: Deoxyribonucleic Acid; CT: Computed Tomography; MRI:
Magnetic Resonance Imaging; RFA: Radiofrequency Ablation; PEI: Percutaneous Ethanol …
HEALTH-RELATED QUALITY OF LIFE AFTER PERCUTANEOUS RADIOFREQUENCY ABLATION OF COLD SOLID BENIGN THYROID NODULES: A 2-YEAR …
R Valcavi, P Tsamatropoulos – Endocrine practice: official journal of the American …, 2015
OBJECTIVE: We studied the impact of Radiofrequency ablation (RFA) on health-related
quality of life (HRQL) in patients with benign thyroid nodules (TN) in a 2-year follow-up.
METHODS: Forty patients (35 female and 5 men; age 54.9±14.3 years) with cold thyroid …
Comparison of laparoscopic radiofrequency ablation versus open resection in the treatment of symptomatic-enlarging hepatic hemangiomas: a prospective study
X Zhang, L Yan, B Li, T Wen, W Wang, M Xu, Y Wei… – Surgical Endoscopy, 2015
Background Radiofrequency ablation (RFA) has been demonstrated to be a promising
therapy for symptomatic large hepatic hemangioma. However, there is a lack of studies to
demonstrate the benefits and disadvantages of RFA as compared with surgical resection …
… mucosal resection on the efficacy and safety of radiofrequency ablation for treatment of Barrett’s esophagus: results from the United States Radiofrequency Ablation …
N Li, S Pasricha, WJ Bulsiewicz, RE Pruitt… – Diseases of the Esophagus, 2015
Summary The effects of preceding endoscopic mucosal resection (EMR) on the efficacy and
safety of radiofrequency ablation (RFA) for treatment of nodular Barrett’s esophagus (BE) is
poorly understood. Prior studies have been limited to case series from individual tertiary …
… MicroRNA-122 Expression is a Poor Prognostic Marker in Patients with Hepatitis B Virus-related Hepatocellular Carcinoma who undergo Radiofrequency Ablation
HJ Cho, JK Kim, JS Nam, HJ Wang, J hee Lee, SS Kim… – Clinical Biochemistry, 2015
Objectives: Aim of this study was to investigate the prognostic potential of plasma microRNA-
122 levels in patients with hepatitis B virus (HBV)-related hepatocellular carcinoma after
hepatic resection or radiofrequency ablation (RFA).
[HTML]… efficacy enough to prevent stroke in atrial fibrillation patient with high CHADS2 score during peri-procedural catheter radiofrequency ablation? A case report with …
XM Shi, FK Chen, Z Liang, J Li, K Lin, JP Guo, ZL Shan – International Journal of …, 2015
Abstract Atrial fibrillation (AF) is a major cause of thromboembolic (TE) events including
stroke and transient ischemic attacks, catheter radiofrequency ablation (CA) has been
demonstrated to effectively eliminate AF in majority of patients. During the peri-procedural …
Right upper lobe lung cancer: Resection through left anterior mediastinotomy
M Sirois, WA Arab, E Turcotte, Y Poulin – Asian Cardiovascular and Thoracic Annals, 2015
… evaluation revealed a forced expiratory volume in 1 s of 1.8 L with carbon dioxide diffusion
capacity of 48% and maximal uptake of oxygen 14 mL min −1 kg −1 . Treatment including
stereotactic body radiation therapy, radiofrequency ablation, and surgery were discussed. …
Magnetic guidance versus manual control: comparison of radiofrequency lesion dimensions and evaluation of the effect of heart wall motion in a myocardial phantom
A Bhaskaran, MAT Barry, SI Al Raisi, W Chik… – Journal of Interventional …, 2015
… Abbreviations MNS Magnetic navigation system MC Manual control 1 Introduction Magnetic
navigation system (MNS) allows remote guidance of ablation catheters during radiofrequency
ablation for cardi- ac arrhythmias. … Page 3. 2.2 MNS versus MC radiofrequency ablation …
Thermal necrosis induced by electrocauterization as a local adjuvant therapy in local aggressive bone tumors, what is the safe limit for surgical margins? An …
M Aydin, K Basarir, M Armangil, HY Yildiz, Y Saglik… – Archives of Orthopaedic and …, 2015
… Majno PE, Mentha G, Mazzaferro V (2010) Partial hepatectomy versus radiofrequency ablation
for hepatocellular carcinoma: confirming the trial that will never be, and some comments on the
indications for liver resection. Hepatology 51(4):1116–1118PubMedView Article; 23. …
Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation
K Hayashi, T Konno, H Tada, S Tani, L Liu, N Fujino… – Circulation: Arrhythmia and …, 2015
Endoscopic Management of Early Esophageal Cancer.
JA Barnes, FF Willingham – Journal of Clinical Gastroenterology, 2015
… proportionately. In the past decade, radiofrequency ablation has become the standard
first-line therapy for high-grade dysplasia when found in the precursor lesion to
esophageal adenocarcinoma, Barrett’s esophagus. Success …
Chronic Regional Pain Syndrome (CRPS/RSD)
V33. Functional imaging of somatosensory finger representation and intracortical inhibition modulation in complex regional pain syndrome
S Strauss, M Grothe, T Usichenko, W Byblow, M Lotze – Clinical Neurophysiology, 2015
Neurophysiological pathology in CRPS type I is characterized by somatosensory and motor deficits.
Transcranial magnetic stimulation (TMS) and functional MRI rev. … Neurophysiological pathology
in CRPS type I is characterized by somatosensory and motor deficits. …
Exploiting resistive cross-point array for compact design of physical unclonable function
PY Chen, R Fang, R Liu, C Chakrabarti, Y Cao, S Yu – Hardware Oriented Security …, 2015
… primitive that leverages the inherent randomness in the physical systems (eg the semiconductor
manufacturing process) to produce a unique response (output) for a given challenge (input)
[1]. Depending on the number of possible challenge-response pairs (CRPs), PuFs can …
Do psychological factors influence recovery from Complex Regional Pain Syndrome Type-1? A Prospective Study.
DJ Bean, MH Johnson, W Heiss-Dunlop, AC Leed… – PAIN, 2015
… Conflicts of Interest: none declared. Running Head: “Psychological factors in the recovery from
CRPS-1” Number of Pages: 19 Number of Tables: 3 Number of Figures: 1 Summary: Amongst
patients with recently-onset CRPS-1, those with higher levels of pain-related …
A comparison of linear and non-linear data assimilation methods using the NEMO ocean model
P Kirchgessner, J Tödter, L Nerger – EGU General Assembly Conference Abstracts, 2015
…pdaf.awi.de), which ensures identical experimental conditions for both filters. To
account for the nonlinearity, the assimilation skill of the two methods is assessed
by using different statistical metrics, like CRPS and Histograms.
The total probabilities from high-resolution ensemble forecasting of floods
J Olav Skøien, K Bogner, P Salamon, P Smith… – EGU General Assembly …, 2015
… Weather Rev., 135(4), 1386-1402, doi:10.1175/MWR3341.1, 2007. Gneiting, T., Raftery,
AE, Westveld, AH and Goldman, T.: Calibrated Probabilistic Forecasting Using Ensemble
Model Output Statistics and Minimum CRPS Estimation, Mon. …
Efficacy of combined physical and occupational therapy in patients with conservatively treated distal radius fracture: randomized controlled trial
V Filipova, D Lonzarić, BJ Papež – Wiener klinische Wochenschrift, 2015
… Two participants from group A and two from group B were suspected of having complex
regional pain syndrome (CRPS) type I yet were not excluded from the trial since there
was no significant deviation regarding the observed variables. …
Combining Graph Analysis and Recurrence Plot on fMRI data
A Lombardi, P Guccione, L Mascolo, P Taurisano… – Medical Measurements and …, 2015
… Even if a visual inspection of CRPs can reveal valuable information about the relationship between
the two systems, the quantification of the structures in CRPs through CRQA has been used for
making more objective the comparison between the time series. Page 3. …
Improving Precipitation Forecasts by Generating Ensembles through Postprocessing
DL Shrestha, DE Robertson, JC Bennett, QJ Wang – Monthly Weather Review, 2015
… In this study, the forecast 3 performance is characterized by evaluating the bias, the Continuous
Ranked Probability Score 4 (CRPS), reliability and Relative Operating Characteristics (ROC)
to assess different aspects of 5 forecast quality. 6 … The mean CRPS (hereafter 16 …
The Forecast Skill Horizon
R Buizza, M Leutbecher – Quarterly Journal of the Royal Meteorological Society, 2015
… theoretical tools are deemed to be impractical to use. We select the continuous ranked probability
score (CRPS, Brown 1974, Hersbach 2000) as metric to decide when the … closer to the observed
CDF (bottom panel). The CRPS is equal to the mean squared error …
Functional Outcomes Following Bridge Plate Fixation for Distal Radius Fractures
A Lauder, S Agnew, K Bakri, CH Allan, DP Hanel… – The Journal of Hand …, 2015
… 2/134 deep infection. 2/134 extensor tendon adhesions. 1/134 EPL rupture. DASH: N/A. Hanel
et al 13, IV: retrospective chart review, 62 pts via chart review, second metacarpal, No CRPS,
1/62 ECRL rupture, 1/62 hardware failure, 0/62 postoperative digit stiffness. DASH: N/A. …
New findings implicated in Coronary calcification in Chronic phase Kawasaki disease
T Yahata, K Ikeda, A Hamaoka, C Suzuki, A Yoshioka… – Circulation, 2015
… tomography. We measured %FMD as an endothelial function marker and hs-CRPs
as an inflammatory marker, serum hydroperoxide and urinary 8-OHdG as oxidative
stress markers, and the bone mineral density (BMD). Patients …
[PDF]Evaluation of the Red Sea State Food Security Status 2007-2009
AAA Ahmed – 2015
… nutrition monitoring using MUAC Since 2006 no nutrition survey conducted. However, EWS
started collecting the nutrition information using the Community Resource Persons (CRPs)
to follow up the nutrition situation in sentinel sites in RPS and Tokar. …
Spatio-temporal circular models with non-separable covariance structure
G Mastrantonio, GJ Lasinio, AE Gelfand – TEST, 2015
Page 1. TEST DOI 10.1007/s11749-015-0458-y ORIGINAL PAPER Spatio-temporal
circular models with non-separable covariance structure Gianluca Mastrantonio1 ·
Giovanna Jona Lasinio2 · Alan E. Gelfand3 Received: 7 …
Predictors of Spinal Cord Stimulation Success
P De La Cruz, C Fama, S Roth, J Haller, M Wilock… – … : Technology at the Neural …, 2015
… Failure, Success. CRPS, Complex Regional Pain Syndrome; FBSS, Failed Back Surgery
Syndrome. Age, Mean + Range, 47.8 + 25.0, 51.2 + 53. Gender, Male : Female, 3:7, 20:27. … Hybrid
(%), 0, 8.1. Indication, FBSS (%), 60, 37.8. CRPS (%), 20, 37.8. Neuritis (%), 20, 24.3. …
Physical Therapy Examination and Assessment
JM David, C OCS, M Ariana Brutico – journal of orthopaedic & sports physical therapy, 2015
… Why Are My Nerves So Sensitive? Neuroscience Education for Patients With CRPS
or RSD. Authors: Ariana Brutico, MSPT, PhD. AFFILIATION: Body Dynamic: Outpatient
Physical Therapy, Pilates, and Yoga Clarks Summit, PA. …
Improved model output statistics of numerical weather prediction based irradiance forecasts for solar power applications
RA Verzijlbergh, PW Heijnen, SR de Roode, A Los… – Solar Energy, 2015
… irradiance is zero. The evaluation of the probabilistic forecasts is carried out using
two metrics. The first is the continuous ranked probability score (CRPS): equation(9).
CRPS ( k ) = 1 T ∑ t = 1 T ∫ x F ̂ t + k | t ( x ) – H ( x – y t + k ) 2.
Thoracic sympathectomy: a review of current indications
M Hashmonai, AEP Cameron, PB Licht, C Hensman… – Surgical Endoscopy, 2015
… However, because the role of the autonomous nervous system is obscure in the pathogenesis
of these disorders, the term “Complex regional pain syndrome” (CRPS) is preferred. … There is
very little good evidence in the literature to guide treatment of CRPS. …
NGF-induced synapse-like structures in contralateral sensory ganglia contribute to chronic mirror-image pain.
CF Cheng, JK Cheng, CY Chen, RH Rau, YC Chang… – Pain, 2015
… image (contralateral) side [21]. This symptom has been observed in many clinical
pain conditions, such as complex regional pain syndrome (CRPS) [23], rheumatoid
arthritis [35], fibromyalgia [4], and neuropathic pain [27]. Mirror …
Process Documentation Research and Impact of Community-Driven Development Grants Research in Rural India, Socioeconomics Discussion Paper Series 34
M Bhattarai, Y Mohan Rao, BL Varalakshmi, VD Duche… – 2015
… Item Type: Socioeconomics Discussion Paper Series. Divisions: RP-Market Institutions
and Policies. CRPS: CGIAR Research Program on Policies, Institutions, and Markets.
Series Name: Socioeconomics Discussion Paper Series. …
SCAMP: A new tool for an old problem
RH Rathod – Journal of Hospital Medicine, 2015
… BWH, Brigham and Women’s Hospital; CRPS, complex regional pain syndrome; EPL, extensor
pollicis longus; PFL, Flexor pollicis longus; MRN, medical record number; N/A, not applicable;
OT, occupational therpay; PA, physician’s assistant. Download figure to PowerPoint. …
Fibromyalgia
Results of an active neurodynamic mobilization program in patients with fibromyalgia syndrome: a randomized controlled clinical trial
JR Torres, IC Martos, IT Sánchez, AO Rubio… – Archives of Physical …, 2015
To examine the effects of an active neurodynamic mobilization program on pain, neurodynamics,
perceived health state and fatigue in patients with fibromyalgia s. … Setting. A local Fibromyalgia
Association. Participants. 48 patients with fibromyalgia syndrome. Interventions. …
The evaluation in terms of sarcopenia of patients with fibromyalgia syndrome
I Koca, E Savas, ZA Ozturk, A Boyaci, A Tutoglu… – Wiener klinische …, 2015
Background Fibromyalgia syndrome (FMS) is an extra-articular rheumatic illness,
characterized by widespread body pain and decreased muscle function. Generalized loss of
muscle mass and strength is named as sarcopenia. The objective of this study was to …
Stigma, Unspeakable Dilemmas, and Somatic Symptoms–a Legacy of Suffering in CFS/ME and Fibromyalgia
J Griffith, N Ryan – Meanings of ME: Interpersonal and Social Dimensions …, 2015
Chronic fatigue syndrome (CFS) and fibromyalgia are both illnesses for which suffering is
amplified by stigmatisation. People with these illnesses often feel judged, devalued,
marginalised, or discriminated against by employers, family members, friends and, most of …
[PDF]Quantitative analysis of nailfold capillary morphology in patients with fibromyalgia
DH Choi, HS Kim – Korean Journal of Internal Medicine, 2015
Background/Aims: Nailfold capillaroscopy (NFC) has been used to examine morphological
and functional microcirculation changes in connective tissue diseases. It has been
demonstrated that NFC patterns reflect abnormal microvascular dynamics, which may play …
Fibromyalgia incidence among patients with hepatitis B infection
L Yazmalar, Ö Deveci, İ Batmaz, D İpek, T Çelepkolu… – International Journal of …, 2015
Aim The purpose of our investigation was to evaluate the incidence of fibromyalgia
syndrome (FMS) and identify FMS-related clinical symptoms in hepatitis B virus (HBV)
patients. Methods One hundred and eighteen HBV surface antigen (HbsAg)-positive …
[PDF]Rheumatology: Current Research
EÖ Bulduk, B Biral – 2015
Page 1. Treatment Approaches of Juvenile Fibromyalgia Syndrome … Abstract Juvenile
fibromyalgia syndrome (JFMS) is an idiopathic long-term health condition characterized
by widespread musculoskeletal pain in children and adolescents. …
Meanings of ME: Interpersonal and Social Dimensions of Chronic Fatigue
CD Ward – 2015
… 10 11 12 13 14 The Challenge of CFS/ME in Primary Care Laura Saunders The Said and the
Unsaid: Ambivalence in CFS/ME Christopher D. Ward Stigma, Unspeakable Dilemmas, and
Somatic Symptoms–a Legacy of Suffering in CFS/ME and Fibromyalgia James Griffith and …
AMPK phosphorylation modulates pain by activation of NLRP3-inflammasome
P Bullon, E Alcocer-Gómez, AM Carrión… – Antioxidants and Redox …, 2015
… Deficient AMPK activation and over-activation of NLRP3-inflammasome axis was also observed
in blood cells from patients with Fibromyalgia (FM), a prevalent human … some pain conditions as
neuropathic pain, fibromyalgia (FM), and complex regional pain syndrome (6,15,16). …
Is Chronic Pain a Disease in Its Own Right? Discussions from a Pre-OMERACT 2014 Workshop on Chronic Pain
AM Taylor, K Phillips, JO Taylor, JA Singh… – The Journal of …, 2015
… In a review of functional disorders36, various mechanisms were proposed to explain the cause
of conditions such as irritable bowel syndrome, fibromyalgia, temporomandibular joint disorder,
and inter- stitial cystitis, including enhanced pain perception, altered brain activation …
Compendium for the Antenatal Care of High-Risk Pregnancies
H Narayan – 2015
AB1222-HPR Hypervigilance to Emotional Subliminal Images in Patients with Fibromyalgia
I Peláez, F Mercado, P Barjola, S Cardoso – Annals of the Rheumatic Diseases, 2015
Background Fibromyalgia (FM) is a chronic condition characterized by the presence of pain,
fatigue and cognitive dysfunction, among other symptoms. Previous research (Duschek et
al., 2014) also indicated that patients show an hypervigilance pattern to pain and negative …
[HTML]Temporal analysis of pain responders and common adverse events: when do these first appear following treatment with pregabalin
J Fink, B Emir, B Parsons, A Clair – Journal of Pain Research, 2015
… Clair Pfizer, New York, NY, USA Background: Pregabalin is an α2δ ligand indicated in the USA
for treatment of a number of chronic pain conditions, including diabetic peripheral neuropathy,
postherpetic neuralgia, pain associated with spinal cord injury, and fibromyalgia. …
SP0133 Juvenile Idiopathic Arthritis and Other Pediatric Rheumatic Diseases
T Avcin – Annals of the Rheumatic Diseases, 2015
… The clinical trials of CCX168, a small molecule antagonist of human C5aR, in human is underway.
Disclosure of Interest: None declared DOI: 10.1136/annrheumdis-2015-eular.6705 FRIDAY, 12
JUNE 2015 WIN session 5 SP0131 FIBROMYALGIA: WHAT IS NEW LJ Crofford. …
Neuropathic pain as part of chronic widespread pain: environmental and genetic influences.
SK Momi, SM Fabiane, G Lachance, G Livshits… – Pain, 2015
…frances.williams@kcl.ac.uk; +44 (0) 20 7188 6765 Keywords: chronic widespread pain;
neuropathic pain; genetic; fibromyalgia; twin ACCEPTED … ABSTRACT Chronic widespread pain
(CWP) has complex aetiology and forms part of the fibromyalgia syndrome. …
SP0130 C5A and its Receptor in Anca-Associated Vasculitis
MH Zhao – Annals of the Rheumatic Diseases, 2015
… The clinical trials of CCX168, a small molecule antagonist of human C5aR, in human is underway.
Disclosure of Interest: None declared DOI: 10.1136/annrheumdis-2015-eular.6705 FRIDAY, 12
JUNE 2015 WIN session 5 SP0131 FIBROMYALGIA: WHAT IS NEW LJ Crofford. …
The spectrum of noncoeliac gluten sensitivity
I Aziz, M Hadjivassiliou, DS Sanders – Nature Reviews Gastroenterology & …, 2015
… with NCGS is described as well as the symptom manifestations commonly reported after gluten
exposure, which include intestinal symptoms consistent with IBS, and extraintestinal symptoms
such as neurological dysfunction, psychological disturbances, fibromyalgia and skin …
Neuro-Bio-Behavioral Mechanisms of Placebo and Nocebo Responses: Implications for Clinical Trials and Clinical Practice
M Schedlowski, P Enck, W Rief, U Bingel – Pharmacological Reviews, 2015
Health-related quality of life improvements among women with chronic pain: comparison of two multidisciplinary interventions
SV Björnsdóttir, M Arnljótsdóttir, G Tómasson, J Triebel… – Disability & Rehabilitation, 2015
… 18,19]. Recently published systematic reviews on multidisciplinary programs for
people with chronic pain [19], chronic low back pain [20] or fibromyalgia syndrome
[21] agree on recommended content in such programs. This …
NGF-induced synapse-like structures in contralateral sensory ganglia contribute to chronic mirror-image pain.
CF Cheng, JK Cheng, CY Chen, RH Rau, YC Chang… – Pain, 2015
… image (contralateral) side [21]. This symptom has been observed in many clinical
pain conditions, such as complex regional pain syndrome (CRPS) [23], rheumatoid
arthritis [35], fibromyalgia [4], and neuropathic pain [27]. Mirror …
Physical Therapy Examination and Assessment
JM David, C OCS, M Ariana Brutico – journal of orthopaedic & sports physical therapy, 2015
… and nerve sensitivity. It is one of several manuals written by the primary author, all
of which discuss concurrent topics involving pain and recovery from injury, including
whiplash, headaches, and fibromyalgia. The manual begins …
by admin | Jun 30, 2015 | Uncategorized
A clinical study conducted by researchers at the Leiden University Medical Center in The Netherlands evaluated the efficacy of a multi-day infusion regimen of intravenous ketamine for the treatment of Chronic Regional Pain Syndrome Type 1. This double blind, placebo-controlled study validated intravenous ketamine as a treatment for CRPS-1, which historically responds poorly to standard pain treatment. Sixty CRPS-1 patients were randomized into groups to undergo infusion therapy for 4.2 days with intravenous ketamine or placebo. The researchers measured pain levels in these patients using a numerical pain score assessment. They found that pain scores over the 12 week study period in patients receiving ketamine were significantly lower compared to those that received placebo (P<0.001). Importantly, after the 12th week, statistical significance between the two groups was lost, indicating that the infusion regimen that the researchers used is not a permanent fix for CRPS-1. Nonetheless, it did provide relatively long lasting relief in a patient population that is desperate for more effective therapies. Intravenous ketamine could be the answer that they’re looking for.
Future studies should focus on the optimal dose of intravenous ketamine and possible synergistic combination drugs to enhance the efficacy of this treatment option for the treatment of chronic pain conditions, like CRPS. A new combination ketamine infusion therapy is offered at the Florida Spine Institute that might just be the answer for long lasting analgesic efficacy. To find out if this procedure is right for your chronic pain, please make an appointment to see Dr. Ashraf Hanna, an expert pain management doctor with significant experience using intravenous ketamine. It is our goal at the Florida Spine Institute to conduct the cutting edge research necessary to eradicate CRPS once and for all.
Full Citation:
Sigtermans, M.J., van Hilten, J.J., Bauer, M.C., Arbous, M.S., Marinus, J., Sarton, E.Y., Dahan, A., 2009. Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1. Pain 145, 304-311.
by admin | Jun 22, 2015 | Uncategorized
Weekly Breaking Research Updates
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Ketamine and Phencyclidine: the good, the bad and the unexpected
D Lodge, MS Mercier – British Journal of Pharmacology, 2015
ABSTRACT: The history of ketamine and phencyclidine from their development as potential
clinical anaesthetics, through drugs of abuse and animal models of schizophrenia to
potential rapidly acting antidepressants is reviewed. The discovery in 1983 of the NMDA …
Intra‐and postoperative low‐dose ketamine for adolescent idiopathic scoliosis surgery: a randomized controlled trial
R Minoshima, S Kosugi, D Nishimura, N Ihara, H Seki… – Acta Anaesthesiologica …, 2015
Background In this randomized controlled trial, we examined whether intra-and
postoperative infusion of low-dose ketamine decreased postoperative morphine
requirement and morphine-related adverse effects as nausea and vomiting after scoliosis …
Period Prevalence of Ketamine-Propofol Admixture “Ketofol” in the Operating Room among Anesthesia Providers at an Academic Medical Center
AN Olson, WR Rao, ME Marienau, NJ Smischney – Medical Science Monitor, 2015
BACKGROUND: The primary aim of this study was to determine the period prevalence of the
single-syringe ketamine-propofol admixture used for sedation and induction among
anesthesia providers during a 5-year period before and after educational sessions …
Electrochemiluminescence immunosensor for ketamine detection based on polyamidoamine-coated carbon dot film
Q Li, W Tang, Y Wang, J Di, J Yang, Y Wu – Journal of Solid State Electrochemistry, 2015
Abstract In this work, we reported the synthesis of water-soluble carbon dots (CDs) by a one-
step hydrothermal synthetic route using polyamidoamine (PAMAM) as platform and
passivant, where the formation of CDs capped with PAMAM and the surface passivation …
Letter to the editor: When what you see might not be what you get: prudent considerations of anesthetics for murine echocardiography
J Wu, J You, S Wang, Y Ye, X Wang, J Jia, Y Zou – American Journal of Physiology- …, 2015
… In their well- designed experiments, the authors compared four popular an- esthetic regimens
(ketamine-xylazine, ketamine alone, avertin, and isoflurane) used in mice during
echocardiographic mea- surement, with conscious state as a reference. …
Ketamine promotes inflammation through increasing TLR4 expression in RAW264. 7 cells
C Meng, Z Liu, G Liu, L Fu, M Zhang, Z Zhang, H Xia… – Journal of Huazhong …, 2015
Summery Ketamine (KTM), a N-methyl-D-aspartate (NMDA) receptor antagonist, was found
to has an anti-inflammatory effect, but some patients suffered from exacerbated pro-
inflammatory reactions after anesthesia with KTM. The present study was aimed to …
The effect of NMDA receptor antagonists and antidepressants on resting state in major depressive disorder
A Dutta – 2015
fMRI ; major depressive disorder ; resting state ; antidepressant ; lanicemine ; ketamine ; citalopram
; anterior cingulate cortex ; NMDA ; glutamate. … Ketamine and other NMDA antagonists have
improved MDD symptoms within 24 hours though the effects are short lasting. …
Assessing Measures of Suicidal Ideation in Clinical Trials with a Rapid-Acting Antidepressant
ED Ballard, DA Luckenbaugh, EM Richards, TL Walls… – Journal of Psychiatric …, 2015
… Received 22 April 2015, Revised 21 May 2015, Accepted 5 June 2015, Available online 16 June
2015. Highlights. • Clinical trials of ketamine and suicide will require appropriate measurement. •
We compared several suicide assessment measures in ketamine clinical trials. • …
d-Cycloserine
AR Durrant, U Heresco-Levy – Encyclopedia of Psychopharmacology, 2015
… of this concept became evident during the last decade when robust antidepressant effects
emerging within 2–4 h and lasting up to more than 2 weeks were obtained and replicated fol-
lowing intravenous administration of single sub-anesthetic doses of ketamine (Krystal et al. …
Depression: Response and Remission
SD Østergaard, GI Papakostas, M Fava – Encyclopedia of Psychopharmacology, 2015
… of this concept became evident during the last decade when robust antidepressant effects
emerging within 2–4 h and lasting up to more than 2 weeks were obtained and replicated fol-
lowing intravenous administration of single sub-anesthetic doses of ketamine (Krystal et al. …
Is pre-emptive administration of ketamine a significant adjunction to intravenous morphine analgesia for controlling postoperative pain? A randomized, double-blind, …
A Fiorelli, A Mazzella, B Passavanti, P Sansone… – … and Thoracic Surgery, 2015
OBJECTIVES To evaluate if the pre-emptive administration of ketamine would potentiate the
effect of intravenous morphine analgesia in the management of post-thoracotomy pain.
METHODS This was a unicentre, double-blind, placebo-controlled, parallel-group, …
Kappa-Opioid Agonists
E Opioid – 2015
… It is considered a precancerous condition. Ketamine … Synonyms Ketalar; Ketaset Definition
Ketamine is an FDA-approved medication for induction and maintenance of anesthesia
in adults. It is a phencyclidine derivative first synthetized in 1962. …
Investigation of the effects of stress on some liver enzymes (AST, ALT, ALP) in rats.
YG Gencer, A Çınar, B Comba – Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 2015
… was applied intraperitoneally (ip) to the experimental group. After 3 h, blood samples
were collected from both groups under ketamine anaesthesia, using appropriate
techniques. The control group serum AST, ALT, ALP values …
Back to the Future: Are Tumor-Targeting Bacteria the Next-Generation Cancer Therapy?
RM Hoffman – Gene Therapy of Solid Cancers, 2015
… 7. Anesthetic reagents (ketamine, xylazine, acepromazine maleate). 8. Kanamycin. 9. Nair. 10. …
1. Four-week-old female mice were anesthetized by a ketamine mixture (10 μl ketamine HCL,
7.6 μl xylazine, 2.4 μl acepromazine maleate, and 10 μl H 2 O) via sc injection. …
[PDF] The Protective Effect of Melatonin vs. Vitamin E in the Ischemic/Reperfused Skeletal Muscle in the Adult Male Rat Model
EA Mohamed – J Cytol Histol S, 2015
… All surgical procedures were performed under anesthesia with IP injection of
Ketamine hydrochloride (Ketame, Egyptian Int. Co. … After 2 hours of reperfusion, the
rats were sacrificed by Ketamine hydrochloride (100 mg/kg) [10]. …
[PDF] CORM2 protects from myocardial ischemia reperfusion injury via modulation of the inflammatory response and apoptosis
NR Hadi, FG Al-Amran, KA Muhsin, A Taher – Journal of Advanced Pharmacy …, 2015
… 2% vials (RompunTM, Bayer AG, Leverkusen, Germany), ketamine (Hikma, Jordan), ethanol
(Fluka, Switzerland) and normal saline (KSA). Rat (IL-1β), (IL- … Surgical LAD ligation The rats were
anesthetized by intraperitoneal injection with a mixture of ketamine and xylazine in a …
[HTML] Long-term correlation of the electrocorticogram as a bioindicator of brain exposure to ionizing radiation
LAA Aguiar, IMS Silva, TS Fernandes, RA Nogueira – Brazilian Journal of Medical and …, 2015
… The irradiation was carried out with the animals anesthetized with 10 mg/kg xylazine and 75
mg/kg ketamine administered intraperitoneally. … To record the ECoG, animals were anesthetized
with 10 mg/kg xylazine and 75 mg/kg ketamine administered intraperitoneally. …
[HTML] The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor
SM de Melo, S Bittencourt, EG Ferrazoli, CS da Silva… – PLOS ONE, 2015
… The animals were anesthetized via the ip injection of a ketamine (100 mg/kg) and xylazine
(10 mg/kg) solution (Syntec, 1356009 and 1720407) and fastened to a stereotaxic
instrument (David Kopf) equipped with a mouse adapter (Enlaup). …
[HTML] Intrarectal Lidocaine-Diltiazem-Meperidine Gel for Transrectal Ultrasound Guided Prostate Biopsy
F Imani, Y Moghaddam, RS Moharari, F Etezadi… – Anesthesiology and Pain …, 2015
… 4, 6) or bupivacaine as a single agent (7). These latter studies have suggested that rectal
administration of lidocaine gel is a safe, simple modality, without any discomfort for patients (8).
Not only local anesthetic agents but also intravenous anesthetic drugs (ketamine) (9) or …
[PDF] Alcohol Withdrawal Syndrome: Improving Outcomes Through Early Identification And Aggressive Treatment Strategies
AF Pizon – 2015
Page 1. June 2015 Volume 17, Number 6 Authors Joseph H. Yanta, MD Medical
Toxicology Fellow, Division of Medical Toxicology, Dept. of Emer- gency Medicine,
University of Pittsburgh Medical Center, Pittsburgh, PA Greg …
Radiofrequency Ablation (RFA)
Use of Contact Force Sensing Technology During Radiofrequency Ablation Reduces Recurrence of Atrial Fibrillation: A Systematic Review and Meta-Analysis
MR Afzal, J Chatta, A Samanta, S Waheed… – Heart Rhythm, 2015
ScienceDirect is phasing out support for older versions of Internet Explorer on Jan 12, 2016.
For the best product experience, we recommend you upgrade to a newer version of IE or
use a different browser: Firefox or Chrome. For additional information please see the …
Comparison of Surgical Resection and Radiofrequency Ablation for Hepatocellular Carcinoma: Take Care Not to Neglect Radiofrequency Technic and Device.
A Hocquelet, M Montaudon, P Balageas, N Frulio… – Annals of Surgery, 2015
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. … Skip Navigation Links Home > …
Effect of different ablation settings on acute complications using the novel irrigated multipolar radiofrequency ablation catheter (nMARQ)
T Deneke, P Müller, P Halbfaß, A Szöllösi, M Roos… – Journal of Cardiovascular …, 2015
Background: Single-shot ablation devices for pulmonary vein isolation (PVI) in patients with
symptomatic atrial fibrillation (AF) have been increasingly used in clinical practice. Objective:
A novel mapping-system integrated irrigated multipolar circular ablation catheter (nMARQ) …
Long-Term Effects of Ganglionated Plexi Ablation on Electrophysiological Characteristics and Neuron Remodeling in Target Atrial Tissues in a Canine Model
X Wang, M Zhang, Y Zhang, X Xie, W Wang, Z Li… – Circulation: Arrhythmia and …, 2015
… Long-Term Effects of Ganglionated Plexi Ablation on Electrophysiological Characteristics and
Neuron Remodeling in Target Atrial Tissues in a Canine Model. … Atrial electrophysiological
characteristics were examined before ablation, immediately and continuously after ablation. …
… to Letter From Bisbal et al Regarding,“Repeat Left Atrial Catheter Ablation: Cardiac Magnetic Resonance Prediction of Endocardial Voltage and Gaps in Ablation …
JL Harrison, C Sohns, NW Linton, R Karim, SE Williams… – Circulation: Arrhythmia and …, 2015
… Tolosana JM,; Arbelo E,; de Caralt TM,; Perea RJ,; Brugada J,; Mont L. CMR-guided
approach to localize and ablate gaps in repeat AF ablation procedure. JACC Cardiovasc
Imaging . 2014;7:653–663. doi: 10.1016/j.jcmg.2014.01.014. …
Pulmonary vein stenosis after pulmonary vein isolation using duty-cycled unipolar/bipolar radiofrequency ablation guided by intracardiac echocardiography
S Asbach, F Schluermann, L Trolese, M Langer… – Journal of Interventional …, 2015
Purpose Concerning rates of pulmonary vein (PV) stenosis were reported following PV
isolation (PVI) with a circular pulmonary vein ablation catheter (PVAC). As this may depend
on intraprocedural imaging, we evaluated the incidence of PV stenosis in patients …
Atrioventricular Block During Slow Pathway Ablation Entirely Preventable?
H Chen, M Shehata, W Ma, J Xu, J Cao, E Cingolani… – Circulation: Arrhythmia and …, 2015
… In a small percentage of cases of AVNRT, it may be necessary to ablate within the CS
with larger atrial potentials, however, ablation at the roof of the proximal CS carries
a high risk of AV nodal block during radiofrequency application. …
Is There Still a Role for CFAE Ablation in Addition to Pulmonary Vein Isolation in Patients with Paroxysmal and Persistent Atrial Fibrillation? A Meta-Analysis of 1,415 …
R Providência, PD Lambiase, N Srinivasan, GG Babu… – Circulation: Arrhythmia and …, 2015
… Is There Still a Role for CFAE Ablation in Addition to Pulmonary Vein Isolation in Patients with
Paroxysmal and Persistent Atrial Fibrillation? … We aimed to assess the impact of CFAE ablation
in addition to pulmonary vein isolation (PVI) in patients undergoing ablation for AF. …
Real-Time Contact Force Measurement A Key Parameter for Controlling Lesion Creation With Radiofrequency Energy
DC Shah, M Namdar – Circulation: Arrhythmia and Electrophysiology, 2015
… Low CF values are also advisable in the vicinity of already ablated sites, where the … for the
acquisition of reliable mapping information and achievement of stable ablation lesions … 183 gs)
as area under curve (red hatched zone) during short duration of radiofrequency (RF) energy …
Atrioventricular Nodal Block With Atrioventricular Nodal Reentrant Tachycardia Ablation
SJ Asirvatham, WG Stevenson – Circulation: Arrhythmia and Electrophysiology, 2015
… a relatively slow stable, junctional rhythm with consistent stable retrograde atrial conduction during
radiofrequency application. … of energy delivery, junctional rhythm may not be seen despite adequate
slow pathway ablation, and the operator may be inclined to ablate at more …
[HTML] Near-infrared spectroscopy integrated catheter for characterization of myocardial tissues: preliminary demonstrations to radiofrequency ablation therapy for atrial …
RP Singh-Moon, CC Marboe, CP Hendon – Biomedical Optics Express, 2015
Abstract Effects of radiofrequency ablation (RFA) treatment of atrial fibrillation can be limited
by the ability to characterize the tissue in contact. Parameters obtained by conventional
catheters, such as impedance and temperature can be insufficient in providing …
A Phase 2, Open-Label, Randomized Study of Pexa-Vec (JX-594) Administered by Intratumoral Injection in Patients with Unresectable Primary Hepatocellular …
CJ Breitbach, A Moon, J Burke, TH Hwang, DH Kirn – Gene Therapy of Solid Cancers, 2015
… Download Protocol (725 KB). Abstract. Primary liver cancer (hepatocellular carcinoma; HCC)
in patients not eligible for surgery or transplant is currently treated by locoregional therapeutic
approaches, including trans-arterial chemoembolization and radiofrequency ablation. …
[PDF] Feasibility and efficacy of helical tomotherapy in cirrhotic patients with unresectable hepatocellular carcinoma
CM Huang, MY Huang, JY Tang, SC Chen, LY Wang… – World Journal of Surgical …, 2015
… Several other treatment modalities for patients with unresectable HCC, including percutaneous
ethanol injection (PEI), radiofrequency ablation (RFA), and transcatheter arterial
chemoembolization (TACE), seem to be more effective in smaller tumors and are contraindicated …
The Wolf-Parkinson-White ECG Pattern-Assessing the Mortality Risk
E Posan – Journal of Insurance Medicine, 2015
… 32. MANAGEMENT. Radiofrequency Ablation Therapy … With pacing maneuvers, the accessory
pathway properties are defined, potential tachycardias are induced, accurate mapping (localization)
of the accessory pathway is achieved and radiofrequency ablation is employed. …
[HTML] Congenital (in growing) osteoma skull in 20-day-old neonate
PG Devi, TS Venkatachalam, YV Sharma, MP Kumar – CHRISMED Journal of …, 2015
… 6. 7. Virayavanich W, Singh R, O’Donnell RJ, Horvai AE, Goldsby RE, Link TM. Osteoid osteoma
of the femur in a 7-month-old infant treated with radiofrequency ablation. Skeletal Radiol
2010;39:1145-9. Back to cited text no. 7. 8. McHugh JB, Mukherji SK, Lucas DR. …
[PDF] Simulating and Optimizing the Response of a Sine Wave Finite state Machine with Timestamp Simulation Using Simulink
M Kalpna, MA Varma – International Journal of Research, 2015
… [5.] Dagmara M. Dołęga, Jerzy Barglik, (2012) “Computer modeling and simulation of
radiofrequency thermal ablation“, COMPEL – The international journal for computation and
mathematics in electrical and electronic engineering, Vol. 31 Iss: 4, pp.1087 – 1095 …
[PDF] Coexistence of permanent junctional reciprocating tachycardia with rheumatic valvular disease; a case sucessfully treated with radiofrequency ablation
M Aydın, A Yıldız, M Yüksel, Y İslamoğlu
Abstract A seventeen years old female had presented with palpitation. On the
electrocardiography (ECG), long RP, narrow QRS tachycardia, inverted P waves in leads
D2, D3 and aVF were noticed. On transthoracic echocardiography, rheumatic mitral …
[PDF] Macrophage Inflammatory Protein Derivative ECI301
T Radiotherapy
… inhibition by ECI301 was not attributable to radiation alone but also shown to other factors such
as the heat generated from high-frequency alter- nating current, namely radiofrequency ablation
(RFA; ref. … 5B), significant differences were ablated by the anti- HMGB1 antibody. …
[PDF] Regenerative Injection Treatment in the Spine: Review and Case Series with Platelet Rich Plasma. J Stem Cells Res
D Aufiero, H Vincent, S Sampson, M Bodor – Rev & Rep, 2015
… back or neck pain refractory to physical therapy, trigger point injections, medial branch blocks,
or radio- frequency ablation. … There is scarce evidence supporting less commonly performed
non-surgical treatments for lumbar radiculopathy including pulsed radiofrequency to the …
[HTML] Modern medicine-morcellation
SC Olmstead
… abandoned as a surgical procedure? What about noninvasive treatment options that
leave the presumed fibroid inside the body, such as uterine artery embolization,
MRI-guided focused ultrasound, and radiofrequency ablation? …
Chronic Regional Pain Syndrome (CRPS/RSD)
What outcome measures are commonly used for Complex Regional Pain Syndrome clinical trials? A systematic review of the literature
S Grieve, L Jones, N Walsh, C McCabe – European Journal of Pain, 2015
… Background and objective. Complex Regional Pain Syndrome (CRPS) is a chronic pain condition,
often triggered by trauma to a limb and characterized by sensory, motor, autonomic and trophic
changes within the affected limb. … 2.4 Classification of CRPS clinical trials. …
[PDF] MIRROR THERAPY: A REVIEW OF EVIDENCES
A Najiha, J Alagesan, VJ Rathod, P Paranthaman – Int J Physiother Res, 2015
… Three particular conditions that have been studied the most are stroke, CRPS and phantom
limb pain. … MT was used in conditions like stroke, cerebral palsy (CP), complex regional pain
syndrome (CRPS), phantom limb pain (PL) and fracture rehabilitation. …
Physical Therapy Treatment for Patients Diagnosed with Complex Regional Pain Syndrome
J Connole – 2015
… Abstract. This case study and evidence-based research analyzes the effects of physical
therapy interventions on a patient diagnosed with type 1 complex regional pain
syndrome (CRPS) to determine the most beneficial treatments. …
Hybrid short-term freeway speed prediction methods based on periodic analysis
Y Zou, X Hua, Y Zhang, Y Wang – Canadian Journal of Civil Engineering, 2015
Page 1. Hybrid short-term freeway speed prediction methods based on periodic
analysis By Yajie Zou, Ph.D. Research associate 133B More Hall, Box 352700
Department of Civil and Environmental Engineering University of …
[HTML] Japanese MD Develops Nutritional Protocols for Gardasil/Cervarix HPV Vaccine Injury
LC Botha – 2015
… subacute sclerosing panencephalitis; CRPS: Complex regional pain syndrome; POTS:
Postural orthostatic tachycardia syndrome; Anti-phospholipid antibody syndrome;
SLE: systemic lupus erythematosus; Rheumatoid arthritis; …
The social behavior of children adopted from Russian Federation: a controlled study
C Caprin, L Ballarin, L Benedan, A Castelli – Psicologia clinica dello sviluppo, 2015
… Nonostante nella ricerca si sia utilizzata la forma estesa per genitori dello strumento
(CRPS-R:L; Conners, validazione Italiana a cura di Nobile, Alberti e Zuddas, 2007), composta
da 80 item (valori di a com- presi fra 0.57 e 0.91 per i maschi e 0.58 e 0.89 per le femmine), in …
A Review of the Use of Stellate Ganglion Block in the Treatment of PTSD
E Lipov, EC Ritchie – Current Psychiatry Reports, 2015
… 14. Lipov EG, Joshi JR, et al. A unifying theory linking the prolonged efficacy of the stellate
ganglion block for the treatment of chronic regional pain syndrome (CRPS), hot flashes,
and posttraumatic stress disorder (PTSD). Med Hypotheses. …
Addiction Recovery in Services and Policy: An International Overview
A Laudet, D Best – Textbook of Addiction Treatment: International …, 2015
… model is growing in popularity nationwide: in the past decade, growing concerns about substance
use on campus and federal agencies’ focus on building a community-based continuum of care
system for youths have fueled a fivefold increase in the number of CRPs, from four …
[HTML] Related Products
R Frank
… 43. Canalith Repositioning Procedures. The recommended treatment for BPPV is a canalith
repositioning procedure (CRP). There are several CRPs described in the literature; the most
studied and used in the United States was first described by Epley in 1992. …
Central habituation and distraction alter C‐fibre‐mediated laser‐evoked potential amplitudes
P Hüllemann, YQ Shao, G Manthey, A Binder, R Baron – European Journal of Pain, 2015
Skip to Main Content. Wiley Online Library. Log in / Register. Log In E-Mail
Address Password Forgotten Password? Remember Me. …
Nuclear Medicine Imaging of Sport Injuries of the Wrist, Hand and Fingers
M Sathekge, FE Suleman, MD Velleman, R Clauss – Nuclear Medicine and …, 2015
… Abductor pollicis longus. CRPS: Chronic regional pain syndrome. … 1997 ). 24.7 Complex Regional
Pain Syndrome (Reflex Sympathetic Dystrophy, Sudeck’s Dystrophy). Complex regional pain
syndrome (CRPS) is one of the most challenging chronic pain conditions of the limbs. …
The Child with a Painful Limp
J Robb – Paediatric Orthopaedic Diagnosis, 2015
… There may be symptoms of psychological distress and further specialist evaluation may
reveal an underlying cause. Complex Regional Pain Syndrome (CRPS). Children with
CRPS type 1 affecting the lower limb often limp (Wilder et al. 1992 ). …
Complex regional pain syndrome type I. An analysis of 7 cases in children
VP Stalla, CM Olaso, VK Almada, GG Rabelino – Neurología (English Edition), 2015
Complex regional pain syndrome (CRPS) is characterised by the presence of pain accompanied
by sensory, autonomic and motor symptoms, usually preceded by a lesio. …
Vitamin C, Extremity Trauma and Surgery
N Shibuya, MR Agarwal, DC Jupiter – 2015
… 987 Abstract Complex regional pain syndrome (CRPS) is a devastating condition often seen
after extrem- ity injury and surgery. … Efficacy and safety of vitamin C used to prevent CRPS are
discussed. List of Abbreviations CRPS Complex regional pain syndrome Introduction …
Psychological Factors as Outcome Predictors for Spinal Cord Stimulation
T Bendinger, N Plunkett, D Poole, D Turnbull – Neuromodulation: Technology at the …, 2015
… SCS trials were offered for the following indications: failed back surgery syndrome (FBSS),
refractory radiculopathy or peripheral neuropathy, complex regional pain syndrome (CRPS),
and refractory angina (at the beginning of observed period—since 2008, this indication is not …
[PDF] The Role of Transitional Justice and Access to Justice in Conflict Resolution and Democratic Advancement
MF Moscati – 2015
… year mandate. The Community Reconciliation Processes (CRPs) of Timor-Leste were created
with the specific aim of dealing with disputes between … perpetrators into their communities. The
possibility of recourse to CRPs was established by the United Nations Transitional …
Complex Regional Pain Syndrome in Children: a Multidisciplinary Approach and Invasive Techniques for the Management of Nonresponders
MJ Rodriguez‐Lopez, M Fernandez‐Baena, A Barroso… – Pain Practice, 2015
… Complex regional pain syndrome (CRPS) is multifactorial condition with complex
pathogenesis characterized by spontaneous or stimulus-induced pain that is
disproportionate to the inciting event. It is also commonly accompanied …
Analgesic response to intravenous ketamine is linked to a circulating microRNA signature in female complex regional pain syndrome patients
SR Douglas, BB Shenoda, RA Qureshi, A Sacan… – The Journal of Pain, 2015
Although ketamine is beneficial in treating complex regional pain syndrome (CRPS), a subset
of patients respond poorly to therapy. We investigated treatment-ind. … Highlights. • We studied
ketamine treatment induced miRNA alterations in blood from CRPS patients. • …
Peptide signalling during the pollen tube journey and double fertilization
LJ Qu, L Li, Z Lan, T Dresselhaus – Journal of Experimental Botany, 2015
… In general, plant peptides can be categorized into two classes: secreted peptides and
non-secreted peptides. Secreted peptides can be further divided into two major classes:
cysteine-rich peptides (CRPs) and non-CRPs (NCRPs). … CRPs are significantly larger peptides. …
[HTML] Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development
J Colling, T Tohge, R De Clercq, G Brunoud, T Vernoux… – Journal of Experimental …, 2015
… Two distinct classes of secreted peptides can be distinguished in plants: small post-translationally
modified peptides such as the CLAVATA3/ENDOSPERM SURROUNDING REGION (CLE) family,
and cysteine-rich peptides (CRPs), exemplified by the EPIDERMAL …
METHODS OF MODULATING DRUG PLASMA LEVELS USING ERYTHROHYDROXYBUPROPION
H Tabuteau – US Patent 20,150,157,582, 2015
… In some embodiments, a combination of dextromethorphan and an antidepressant, such as
bupropion, may be administered to relieve complex regional pain syndrome, such as complex
regional pain syndrome type I (CRPS-I), complex regional pain syndrome type 11 (CRPS-II …
METHODS FOR THE SAFE ADMINISTRATION OF IMIDAZOLE OR IMIDAZOLIUM COMPOUNDS
H Tabuteau – US Patent 20,150,157,564, 2015
… embodiments, an osteoclast inhibitor, such as a nitrogen-containing bisphosphonate, eg
zoledronic acid, ibandronic acid or minodronic acid, may be administered to relieve complex
regional pain syndrome, such as complex regional pain syndrome type I (CRPS-I), complex …
Fibromyalgia
The Use of Polysymptomatic Distress Categories in the Evaluation of Fibromyalgia (FM) and FM Severity
F Wolfe, BT Walitt, JJ Rasker, RS Katz, W Häuser – The Journal of Rheumatology, 2015
Objective The polysymptomatic distress (PSD) scale is derived from variables used in the
2010 American College of Rheumatology (ACR) fibromyalgia (FM) criteria modified for
survey and clinical research. The scale is useful in measuring the effect of PSD over the …
Association of different levels of depressive symptoms with symptomatology, overall disease severity, and quality of life in women with fibromyalgia
A Soriano-Maldonado, K Amris, FB Ortega… – Quality of Life Research, 2015
Purpose This study examined the associations of different levels of depression with pain,
sleep quality, fatigue, functional exercise capacity, overall fibromyalgia (FM) severity, and
health-related quality of life (HRQoL) in women with FM. Methods A total of 451 women …
Fibromyalgia: Clinical Guidelines and Treatments
E Lawson, M Wallace – 2015
Major Classes of Medication for Treatment of Fibromyalgia
AM Kelly, K Mauer – Fibromyalgia: Clinical Guidelines and Treatments, 2015
Implications of proposed fibromyalgia criteria across other functional pain syndromes
N Egloff, R von Känel, V Müller, UT Egle… – Scandinavian Journal of …, 2015
Objectives: In 2010, the American College of Rheumatology (ACR) proposed new criteria for
the diagnosis of fibromyalgia (FM) in the context of objections to components of the criteria of
1990. The new criteria consider the Widespread Pain Index (WPI) and the Symptom …
Omar I. Halawa and David A. Edwards
DA Edwards – Fibromyalgia: Clinical Guidelines and Treatments, 2015
Psychophysiological Methods
RH McAllister-Williams – Encyclopedia of Psychopharmacology, 2015
… potential. Tramadol reduces pain substantially in osteoarthritis and fibromyalgia
(Bennett et al. 2003). Methadone … below). There is evidence of a mild degree of benefit
in low back pain, fibromyalgia, and headaches. Anticonvulsant …
PTSD and Fibromyalgia Syndrome: Focus on Prevalence, Mechanisms, and Impact
W Häusera, J Ablinb, B Walittc – 2015
Abstract The association between fibromyalgia syndrome (FMS) and posttraumatic stress
disorder (PTSD) is of growing interest in psychosocial research. The mechanisms by which
both disorders are interconnected are not well understood. The article presents an …
Conditioned Pain Modulation: Neurophysiological, Cognitive, And Pharmacological Aspects
RR Nir, D Yarnitsky – Topics in Pain Management, 2015
… The relevance of modulatory pain mechanisms in the clinical arena is represented through
cumulative research reporting impaired pain inhibition associated with pain disorders, particularly
fibromyalgia, irritable bowel syndrome, migraine, tension-type headache …
Ryan D. McConn and Magdalena Anitescu
RD McConn – Fibromyalgia: Clinical Guidelines and Treatments, 2015
[HTML] Another dimension of pain
TH Khan – Anaesth Pain & Intensive Care, 2015
… Pain Manag Nurs. 2013 Dec;14(4):368-78. [PubMed] doi: 10.1016/j.pmn.2011.08.001. Menzies
V, Taylor AG, Bourguignon C. Effects of guided imagery on outcomes of pain, functional status,
and self-efficacy in persons diagnosed with fibromyalgia. J Altern Complement Med. …
[HTML] Pattern of irritable bowel syndrome and its impact on quality of life: A tertiary hospital based study from Kolkata on newly diagnosed patients of irritable bowel …
U Sinharoy, K Sinharoy, P Mukhopadhyay… – CHRISMED Journal of …, 2015
… [6],[7],[8],[9] IBS can coexist with other functional disorders, most notably fibromyalgia, chronic
fatigue syndrome … 10. 11. Aaron LA, Burke MM, Buchwald D. Overlapping conditions among
patients with chronic fatigue syndrome, fibromyalgia, and temporomandibular disorder. …
[PDF] Disability Status, Disability Type, and Training as Predictors of Job Placement
J Stahl – 2015
… Deafness Hearing, Communicating Deafness Neurological Memory, Speaking TBI, Multiple
Sclerosis, Fibromyalgia Developmental Reading, Writing, Speaking Autism, Williams Syndrome …
Mental Neurological Memory, Speaking TBI, Multiple Sclerosis, Fibromyalgia …
[HTML] Pilates for Fibromyalgia
DPT Tom Lavosky, C MDT
By Gabrielle Shirer As originally seen in the Fall 2006 edition of the Pilates Coreterly
According to the National Fibromyalgia Association, Fibromyalgia Syndrome (FMS) is an
increasingly recognized chronic pain illness characterized by widespread …
New study by guidelines author dismisses risk of chronic Lyme disease
D Cameron
… In addition, these patients were not more prone to developing fibromyalgia and/or chronic fatigue,
according to two additional papers by Dr. Wormser. … [1]. And previous studies report there’s a
high risk of developing fibromyalgia after having Lyme disease. …
[HTML] Evolution of Skin Temperature after the Application of Compressive Forces on Tendon, Muscle and Myofascial Trigger Point
MF Magalhães, AV Dibai-Filho, EC de Oliveira Guirro… – PLOS ONE, 2015
… of musculoskeletal, tendon or nervous injuries in the upper limb, history of fracture in the upper
limb, use of painkillers, anti-inflammatory drugs or muscle relaxants during the previous week,
presence of systemic or neuromuscular diseases, and medical diagnosis of fibromyalgia …
[HTML] Rejuvenate With Stem Cells
R Schilling – 2015
… literature. This combination (laser activated, intravenous mesenchymal injection) has
the potential for being useful for a multitude of chronic illnesses like fibromyalgia,
MS, generalized arthritis, just to mention a few. Mesenchymal …
[PDF] Regenerative Injection Treatment in the Spine: Review and Case Series with Platelet Rich Plasma. J Stem Cells Res
D Aufiero, H Vincent, S Sampson, M Bodor – Rev & Rep, 2015
… Positive results for Prolotherapy have been published for a variety of conditions including lateral
epicondylosis [21], osteoarthritis [22], sacroiliac joint pain [23], chondromalacia patellae [24],
fibromyalgia [25], chronic groin pain [26] and Osgood-Schlatter disease [27]. …
[PDF] APPROVAL SHEET
M Holman – 2015
… Page 14. Effect of US and Graston on Muscle Contraction 11 plantar fasciitis,
patellofemoral disorders, fibromyalgia, scar tissue, and trigger finger. 13 The Graston
Technique allows for controlled application of friction massage to the …
[HTML] Blueg rass Doctors of Physical Therapy, PLLC Physical Therapy Care Provider in the Louisville, Kentucky We provide EXPERT CARE for YOUR Health!
N Patient, C Forms
… There are many symptoms that can lead the person with fibromyalgia syndrome (FMS)
and/or chronic myofascial pain (CMP) to your office. … Research indicates that fibromyalgia
may increase the risk of cardiovascular disease (Curtis, O’Keefe Jr 2002). …
by admin | May 22, 2015 | Uncategorized
Weekly Breaking Research Updates, May 22, 2015
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates. The title of each article below is a link to the full study report. If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
[HTML] Exaggerated Acute Lung Injury and Impaired Antibacterial Defenses During Staphylococcus aureus Infection in Rats with the Metabolic Syndrome
X Feng, M Maze, LG Koch, SL Britton, J Hellman – 2015
… All procedures were performed under ketamine and xylazine anesthesia, and all efforts
were made to minimize suffering. Animals. The … edema. At 48 h, the rats were sacrificed
under deep anesthesia provided by ketamine/xylazine. …
Drugs that Target the Glutamate Synapse: Implications for the Glutamate Hypothesis of Schizophrenia
CA MIELNIK, A RAMSEY – Drug Discovery for Schizophrenia, 2015
… In addition to the ligand bind- ing domains, NMDA receptors have modulatory sites for
zinc and spermine, and a modulatory site within the channel that binds the
non-competitive inhibitors phencyclidine (PCP), dizocilpine, and ketamine. …
EVALUATION OF ANTHELMINTIC FISHMEAL POLYMER BAITS FOR THE CONTROL OF BAYLISASCARIS PROCYONIS IN FREE-RANGING RACCOONS ( …
TJ Smyser, SR Johnson, MD Stallard, AK McGrew… – Journal of Wildlife Diseases, 2015
… lactating were released at the capture location. We anesthe- tized captured raccoons
with ketamine/xyla- zine (10 mg/kg ketamine and 2 mg/kg xylazine, intramuscularly
[Fowler 2009]). Upon induc- tion, animals were weighed …
[PDF] Intra-ventral tegmental HIV-1 Tat1-86 attenuates nicotine-mediated locomotor sensitization and alters mesocorticolimbic ERK and CREB signaling in rats
J Zhu, NM Midde, AM Gomez, W Sun, SB Harrod – Name: Frontiers in Microbiology, 2015
… session 29 (Fig 1A). 30 Briefly, rats were anesthetized using a mixture of ketamine
hydrochloride and xylazine 31 by intraperitoneal (IP) injection (7.5 mg ketamine/100
g b.wt. and 30 mg xylazine/100 g b.wt.). 32 Rats were then …
Autonomic remodeling: How atrial fibrillation begets atrial
L Zhang, SS Po, HW PhD&, BJ Scherlag, HL PhD&… – 2015
… 13 Fifty-two male adult New Zealand white rabbits, weighing 2.0–2.5 kg, were 14 premedicated
with ketamine/xylazine ( 35mg/5mg/kg ),and restrained in the 15 supine position. Anesthesia
was also maintained by intra-peritoneal injection of 16 20% urethane 5 ml as needed. …
Protein Interactions with Dopamine Receptors as Potential New Drug Targets for Treating Schizophrenia
P SUa, AHC WONG, F LIU – Drug Discovery for Schizophrenia, 2015
… Page 222. Chapter 9 208 antagonist, ketamine, or PCP-induced cognitive deficits with an
inverted U-shaped dose response curve. … 52 Conversely, there is less ketamine-induced
behavioral activation in D1R knockout mice than in wild-type mice. …
Plasma arginine metabolites reflect airway dysfunction
H Grasemann, JA Scott, ML North, M Rafii, H Huang… – J Appl Physiol, 2015
… On day 21, 24 h after the final aerosol challenge, mice were anesthetized (ketamine/xylazine)
for tracheal and jugular venous cannulations for ventilator-based measurement of respiratory
function and infusion of the stable L-arginine isotopomer cocktail, respectively. …
[PDF] Histological and Histomorphometric Evaluation of Pharmacological Action of the Essential Oil of Melaleuca Alternifolia on Healing of Infected Alveolitis in Experimental …
WS Abdel-fattah, MM Dahaba, AA Ahmed… – J Interdiscipl Med Dent Sci, 2015
… Materials and Methods Chemicals Tea tree oil was purchased from (SIGMA-ALDRICH
Chemie GmbH RiedstrasseUSA), vancomycin hydrochloride and ketamine were
obtained from the local pharmaceutical market. Bacterial infection …
[PDF] Clinical Evaluation of Caudal Clonidine as an Adjuvant to Bupivacaine in Pediatric Patients Undergoing Sub Umbilical Surgeries
S Dalal – 2015
… Prolongation of caudal analgesia using a single-shot technique has been achieved by addition
of various adjuvants, such as epinephrine, opioid, ketamine, and alpha 2 agonists [9]. Clonidine,
an alpha 2 agonist has extensively been used in neuraxial blocks [10- 13] and …
The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats
E Taslidere, N Vardi, M Esrefoglu, B Ates, C Taskapan… – Human & Experimental …, 2015
… kg body weight for 20 days. At the end of the experiment, rats were killed by ketamine
anesthesia. After blood samples were collected from tail vein, livers were removed
and divided into two portions. One sample was used for …
[PDF] Assessment of the effect of ketamine on cytochrome P450 isoforms activity in rats by cocktail method
F Lin, Y He, L Zhang, M Zhang, Y Zhang, C Wen – Int J Clin Exp Med, 2015
Abstract: Cocktail method was used to evaluate the influence of ketamine on the activities of
CYP450 isoforms CYP1A2, CYP2D6, CYP3A4, CYP2C19, CYP2C9 and CYP2B6, which
were reflected by the changes of pharmacokinetic parameters of six specific probe drugs …
Ketamine and suicidal ideation in depression: Jumping the gun?
R Rajkumar, J Fam, EYM Yeo, GS Dawe – Pharmacological Research, 2015
Abstract Depression and suicide are known to be intricately entwined but the
neurobiological basis underlying this association is yet to be understood. Ketamine is an N-
methyl D-aspartate (NMDA) receptor antagonist used for induction and maintenance of …
Ketamine-mediated alleviation of electroconvulsive shock-induced memory impairment is associated with the regulation of neuroinflammation and soluble amyloid- …
X Zhu, P Li, X Hao, K Wei, S Min, J Luo, F Xie, J Jin – Neuroscience Letters, 2015
Abstract Electroconvulsive therapy (ECT) is an effective treatment for depression, but can
result in memory deficits. This study aimed to determine whether ketamine could alleviate
electroconvulsive shock (ECS, an analogue of ECT in animals)-induced memory …
D-AMPHETAMINE withdrawal-induced decreases in brain-derived neurotrophic factor in sprague-dawley rats are reversed by treament with ketamine
JJL Fuller, RC Murray, KA Horner – Neuropharmacology, 2015
Abstract Withdrawal from chronic D-amphetamine (D-AMPH) can induce negative emotional
states, which may contribute to relapse and the maintenance of addiction. Diminished levels
of brain-derived neurotrophic factor (BDNF), particularly in the hippocampus has been …
Management of acute pain in patients on treatment with opioids
J De Andres, G Fabregat-Cid, JM Asensio-Samper… – Pain Management, 2015
… In fact, the use of NMDA receptor antagonists such as ketamine inhibits the development of
tolerance in test animals [15]. … Inhibition of tolerance has been demonstrated in test animals with
the use of noncompetitive antagonists of NMDA receptors such as ketamine [48]. …
DrugScan
T Ha, L Abbott, J Booth, M Morrow, M Rawlins… – 2015
… Emerg Med J 2014; 31: 706–13. Ketamine and Intraocular Pressure in Children This prospective
observational study sought to examine the potential increase in the intraocular pressure following
ketamine administration for paediatric procedural seda- tion. …
Multimodal Analgesic Protocol and Postanesthesia Respiratory Depression During Phase I Recovery After Total Joint Arthroplasty.
TN Weingarten, AK Jacob, CW Njathi, GA Wilson… – Regional Anesthesia and …, 2015
… Procedural sedation during block placement was with incremental dosing of intravenous midazo-
lam, fentanyl, and ketamine. … Use of ketamine as a sedative for nerve blockade or analgesia was
at the discretion of the attending anesthesiologist and not part of the protocol. …
Stem cell-based therapies for intracerebral hemorrhage in animal model: a meta-analysis
X Ma, J Qin, B Song, C Shi, R Zhang, X Liu, Y Ji, W Ji… – Neurological Sciences, 2015
… CAMARADES) [10]: peer- reviewed publication; statement of control of tem- perature; random
allocation to treatment or control; blinded induction; blinded assessment of outcome; use of
anesthetic without significant intrinsic neuroprotec- tive activity (such as ketamine); use of …
Anatomical organization of the visual dorsal ventricular ridge in the chick (Gallus Gallus): Layers and columns in the avian pallium
P Ahumada‐Galleguillos, M Fernandez, GJ Marin… – Journal of Comparative …, 2015
… Deposits of biocytin in vital slices. Forty chicks (P1-P5) were deeply anesthetized with a mixture
(3:1) of 1% Ketamine and 2% Xylazine, and then decapitated. … Deposits of DiI in fixed slices. Ten
chicks were deeply anesthetized using the Ketamine/Xilazine mixture and perfused …
[PDF] Alterations in molecular pathways in the retina of early experimental glaucoma eyes
L Cao, L Wang, G Cull, A Zhou – Int J Physiol Pathophysiol Pharmacol, 2015
… in one eye of each animal under ketamine and xyla- zine anesthesia. One hundred … follow-
up. During each test, IOP was measured by a rebound tonometer (Tonopen XL, Reichert
Inc) under ketamine and xylazine anesthesia. The peripapillary …
Radiofrequency Ablation (RFA)
… K Antagonist Oral Anticoagulants versus Vitamin K Antagonist Oral Anticoagulants in Patients Undergoing Radiofrequency Catheter Ablation of Atrial Fibrillation: A …
G Santarpia, S De Rosa, A Polimeni, S Giampà… – PloS one, 2015
BACKGROUND: Use of the non-vitamin K antagonist oral anticoagulants (NOACs) is
endorsed by current guidelines for stroke prevention in patients with atrial fibrillation (AF).
However efficacy and safety of NOACs in patients undergoing catheter ablation (RFCA) of …
Treatment of Renal Cell Carcinomas
SN Kurukkal, SS Al-Busaidy – Urological Cancer Management, 2015
… cavitational ultrasound (PCU). However, only two ablation therapies are recommended
by expert panels for the treatment of renal tumours: cryoablation and radiofrequency
ablation. … hilum. 16.3.1 Radiofrequency Ablation (RFA). It is …
[PDF] Metastatic Colorectal Cancer: Review of Diagnosis and Treatment Options
M Palaghia, CC Prelipcean, E Cotea, N Vlad… – Journal of Surgery [Jurnalul …, 2015
… Liver Metastases: Addition of new, multidisciplinary techniques and therapies like systemic or
local chemotherapy, radiofrequency ablation (RFA), cryotherapy and radiotherapy improves the
rate of liver metastases resectability but currently there is no gold standard concerning …
ть е рыв ж ть
H Takeuchi – 2015
… transplantation and as a radiofrequency ablation for AF [3]. Sixty-four-slice multidetector CT
(64-MDCT) becomes an option to evaluate coronary artery stenosis. … pulmonary venous stenosis
following radiofrequency ablation. Respiratory Care 2004; 49:1525-7. …
[PDF] The natural product sulforaphane inhibits breast cancer stem cell targets in triple negative and trastuzumab-resistant breast cancers
J Burnett – 2015
… metastasis (1). Substantial progress has been made with respect to the treatment of primary
tumors using surgery, chemotherapy, radiation therapy, and radiofrequency ablation. However,
the advancement of cancer to an invasive or metastatic stage is …
[HTML] Multidisciplinary management of advanced lung neuroendocrine tumors
PL Filosso, P Ferolla, F Guerrera, E Ruffini, WD Travis… – Journal of Thoracic Disease, 2015
… In the absence of hormonal control, many patients may benefit of SSA or Interferon,
associated with loco-regional therapies (liver palliative surgery, radiofrequency metastasis
ablation or trans arterial chemoembolization). Low-grade NETs. …
[PDF] Minimally-invasive Therapy in Thyroid Practice
L Hegedüs
… Ethanol ablation (PEI) • Laser ablation (ILP) • Radiofrequency ablation (RFA • Laszlo Hegedüs •
Enrico Papini (Rome, Italy) • Jung Hwan Baek (Seoul) Ford T Maserati Quatroporte Proto Spirra …
Radiofrequency Ablation (RFA) Page 21. 5/13/2015 21 P < 0,0001 RFA Obs. …
[PDF] 0915-0940 TBD 0940-1000 Coffee break/Poster viewing
M Kudo, G Abou-Alfa, O Baatarkhuu, RN Chien… – Surgery
… Prof Ho Yeong Lim (Korea) 1535-1555 Novel techniques: ablation Dr Shuichiro
Shiina (Japan) Circulating biomarkers Dr Wei Tang (Japan) 1555-1615 Surgery
vs. ablation: a new balance in the era of new technologies? …
Urological Cancer Management
SA Al-Mamari, SS Al-Busaidy
… time PSM Positive surgical margins PTH-rP Parathormone-related peptide pTNM Pathological
TNM QoL Quality of life RALP Robotic assisted laparoscopic radical prostatectomy RC Radical
cystectomy RCC Renal cell carcinoma RFA Radiofrequency ablation RN Radical …
[DOC] Deliverable 11
B Plan
… Introduction. Ablatech Inc. is a novel company developing a direct current (DC) Ablation device
for the treatment of fibroadenomas and lipomas. … Note: The DC Ablation generator is indicated
for use with Ablatech’s A2500 series of delivery needles, which are sold separately. …
Radiofrequency ablation for treatment of hereditary hemorrhagic telangiectasia lesions:“How I do it”
B Rotenberg, S Noyek, CJ Chin – American Journal of Rhinology & Allergy, 2015
Introduction: Hereditary hemorrhagic telangiectasia (HHT) can cause significant epistaxis for
those that suffer from it. Traditaional surgical treatments are ablative and can cause thermal
damage. Radiofrequency (RF) energy can potentially be used to ablate HHT plaques at a …
Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients
A Facciorusso, V Del Prete, N Crucinio, N Muscatiello… – Journal of Gastroenterology …, 2015
Methods Data on 153 patients were reviewed. The study population was classified into three
groups: 73 (47.8%) patients who received neither angiotensin converting enzyme inhibitors
nor sartans (Group 1), 49 (32%) patients treated with angiotensin converting enzyme …
Ablative therapies: Advantages and disadvantages of radiofrequency, cryotherapy, microwave and electroporation methods, or how to choose the right method for an …
O Seror – Diagnostic and Interventional Imaging, 2015
… It is important, however, to understand that each of the ablated regions created remains … as possible
the functional liver parenchyma which implies to not ablate too large … No touch multibipolar
radiofrequency ablation for single liver metastases: a: axial computed tomography at …
Pulmonary Vein Stenosis After Minimally Invasive Stand‐alone Surgical Ablation of Atrial Fibrillation
E Abo‐salem, J Munjal, S Kapur – Journal of Cardiac Surgery, 2015
… vein. In our case, several rounds of cryoablation alternating with radiofrequency ablation
were also applied to confirm a transmural block. An extensive ablation strategy may
have contributed to the development of stenosis. Aggressive …
[PDF] Comparative study between conventional chemo-embolization and chemo-embolization using drug eluting beads as alternative methods for treatment of …
RS Elshahat, HA Ahmed, OI Saleh, EEA Ibrahim… – Life Science Journal, 2015
… Although preliminary screening and diagnosis have allowed HCC patients to benefit from radical
resection, transplantation, or radiofrequency ablation, tumors in some patients still progress rapidly
because of local spreading or metastases, particularly in those with background …
Treatment of hepatocellular carcinomas by thermal ablation and hepatic transarterial chemoembolization
P Chevallier, G Baudin, R Anty, A Guibal, M Chassang… – … and Interventional Imaging, 2015
… It has now been shown for monopolar radiofrequency ablation that this therapy
alone is sufficient to effectively treat single HCCs < 3 cm in diameter provided that
liver micrometastases are not present. If the HCC is >3 cm in …
The “Duality” of Idiopathic Ventricular Arrhythmias from the Left Ventricular Ostium
DJ Callans, P Santangeli – Pacing and Clinical Electrophysiology, 2015
… LBBB, the other RBBB which were ablated from a single region. These patients were identified
from a series of 247 patients with idiopathic outflow tract PVCs. The methods included
electroanatomic mapping, irrigated radiofrequency ablation and site verification …
nonsystemic treAtment of Liver metAstAses from neuroendocrine tumor
D Putzer, G Widmann, D Waitz, W Jaschke, IJ Virgolini – … Analogues: From Research …, 2015
… 274 NONsYsTEMIC TREATMENT Of LIVER METAsTAsEs RfA radiofrequency ablation RILD
radiation‐induced liver disease sIRT selective internal radiation therapy sPECT single photon
emission computed tomography TACE transarterial chemoembolization Us ultrasound …
Interventional oncology for liver and lung metastases from colorectal cancer: The current state of the art
T de Baere, L Tselikas, E Pearson, S Yevitch, V Boige… – … and Interventional Imaging, 2015
… tissue causes cooling through convention, which is responsible for the “heat sink effect”, and
causes difficulties in ablating tissue close to … The hepatic recurrence rate in 6025 patients
undergoing surgery with or without radiofrequency ablation for malignant liver metastases from …
One Year Incidence of Atrial Septal Defect After PV Isolation: A Comparison Between Conventional Radiofrequency and Cryoballoon Ablation
G Mugnai, J Sieira, G Ciconte, MS Hervas, G Irfan… – Pacing and Clinical …, 2015
Background: Transseptal (TS) catheterization is needed to access the left heart during
pulmonary vein isolation (PVI) procedures. In the radiofrequency (RF) ablation procedure,
left atrial access is commonly achieved with a double TS puncture; cryoballoon (CB) …
Complex Regional Pain Syndrome (CRPS/RSD)
[PDF] Topics on estimation, prediction and bounding risk for multivariate extremes
RA Yuen – 2015
… 17 2.3 CRPS M-estimation for max-stable models . . . . . 20 2.4 Simulation . . . . . … 141
A.1 Code for fitting max-linear models via CRPS . . . . . 142 A.2 Code for fitting a
Tawn-Molchanov max-stable model . . . . 144 BIBLIOGRAPHY . . . . . …
[PDF] A NOVEL APPROACH TO THE MANAGEMENT OF PARSONAGE-TURNER SYNDROME
DK Garas, MD Rano Faltas, ER Viscusi
… refractory CRPS, and has been found to be particularly efficacious6. • In a study
of 25 patients with refractory CRPS who underwent surgery, IV ketamine …
exacerbations or spread of their CRPS at their 3 month evaluation6, 13.
[PDF] Preliminary Port Recovery Plan Schedule 2: Regional Coastal Environment Plan for the Canterbury Region (RCEP) Provisions-Specific Changes Sought (or wording …
L Port, P Page – policy
… for by policies, rules and other methods set out in the RCEP. These changes sought are consistent
with the CRPS as set in Schedule 1. … These changes sought are consistent with the CRPS as set
out in Schedule 1. Amendments sought to Action 7 are Insert a new policy: …
Organisational Complaint Management
S Garding, A Bruns – Complaint Management and Channel Choice, 2015
… 2013). Garnefeld et al. (2013) even recommend companies to consider “building CRPs
into social media campaigns to take advantage 6 1 Organisational Complaint
Management Page 7. of the increasing social commerce opportunities”. …
[PDF] Reverse total shoulder arthroplasty for complex proximal humeral fractures in the elderly: How to improve outcomes and avoid complications
RPDM UCT, F Ortho, UCT MMed Orth, BVM Zim, F Orth… – pain
… 139 (90–180) – 27 (0–45) 1 (VAS) 10% 1 patient with CRPS, DVT, and GT resorption, 1 patient
with GT malunion, 1 patient with Grade 1 notching ASES 78 T a b le I: R esu lts o … RTSA 9
133(±20) 41 (±19) 1 (±1) 1/9 CRPS (recovered) ASES 80 (±11) T a b le II: R esu lts fo r stu …
[PDF] Syringomyelia & Spinal Cord Stimulation
RB Pitkanen, DL James
… found to be successfully used in the treatment of several neuropathic pain syndromes
such as radiculopathy, failed back surgery syndrome, CRPS, post-herpetic neuralgia,
as well as to a lesser extent for chronic migraine, refractory …
[PDF] Neuropsychology of Chronic Pain
EM Desensitization
… For example, com- plex regional pain syndrome (CRPS) is caused by a disturbance of the
sympathetic nervous system— the network of nerves located along the spinal cord that controls
bodily functions such as the opening and closing of blood vessels and sweat glands. …
Stefan Garding Andrea Bruns
SBIN BUSINESS
… 2013). Garnefeld et al. (2013) even recommend companies to consider “building CRPs
into social media campaigns to take advantage 6 1 Organisational Complaint Management
Page 19. of the increasing social commerce opportunities”. …
” What I really needed was the truth”. Exploring the information needs of people with Complex Regional Pain Syndrome
S Grieve, C McCabe, J Adams – Musculoskeletal Care, 2015
… Download (52Kb) | Request a copy: Description/Abstract. Background United Kingdom
guidelines indicate individuals with Complex Regional Pain Syndrome (CRPS) require
information and education to support self management. …
Reprogramming of in situ spinal cord stimulator for covering newly developed postthoracotomy pain
NN Knezevic, MV Rana, P Czarnocki… – Journal of Clinical …, 2015
… Postthoracotomy pain; Spinal cord stimulation. 1. Introduction. Spinal cord stimulation has become
increasingly successful in the treatment of pain syndromes, especially neuropathic pain, ranging
from failed back surgery syndrome to complex regional pain syndrome (CRPS). …
Late Amputation May Not Reduce Complications or Improve Mental Health in Combat-Related, Lower Extremity Limb Salvage Patients
CA Krueger, JC Rivera, DJ Tennent, AJ Sheean… – Injury, 2015
… Table 2. Documented reasons of why the limb salvage patients wanted a late amputation. CRPS:
Chronic Regional Pain Syndrome. Reasons for Desired Late Amputation, (n, %), … Lack of joint
motion, 6, 13%. Lack of strength, 4, 9%. Skin coverage or flap failure, 2, 5%. CRPS, 1, 2% …
Community-Based Review of Research Across Diverse Community Contexts: Key Characteristics, Critical Issues, and Future Directions
N Shore, A Ford, E Wat, M Brayboy, ML Isaacs, A Park… – American Journal of Public …, 2015
… These community-based research review processes (CRPs) can provide individual and
community-level ethics protections, enhance the cul- tural relevance of study de- signs and
competence of re- searchers, build community and academic research capac- ity, and shape …
Bayesian Model Averaging with Stratified Sampling for Probabilistic Quantitative Precipitation Forecasting in Northern China during Summer 2010
J Zhu, F Kong, L Ran, H Lei – Monthly Weather Review, 2015
Page 1. Monthly Weather Review EARLY ONLINE RELEASE This is a preliminary PDF of
the author-produced manuscript that has been peer-reviewed and accepted for publication.
Since it is being posted so soon after acceptance, it has not yet been …
COMPOSITIONS AND METHODS OF USING THREOHYDROXYBUPROPION FOR THERAPEUTIC PURPOSES
H Tabuteau – US Patent 20,150,133,485, 2015
… In some embodiments, a combination of dextromethorphan and an antidepressant, such as
bupropion, may be administered to relieve complex regional pain syndrome, such as complex
regional pain syndrome type I (CRPS-I), complex regional pain syndrome type II (CRPS-II …
BUPROPION AS A MODULATOR OF DRUG ACTIVITY
H Tabuteau – US Patent 20,150,133,486, 2015
… In some embodiments, a combination of dextromethorphan and an antidepressant, such as
bupropion, may be administered to relieve complex regional pain syndrome, such as complex
regional pain syndrome type I (CRPS-I), complex regional pain syndrome type II (CRPS-II …
Osteoclast Inhibitors for Knee Conditions
H Tabuteau, G Jones – US Patent 20,150,133,403, 2015
… embodiments, an osteoclast inhibitor, such as a nitrogen-containing bisphosphonate, eg
zoledronic acid, ibandronic acid or minodronic acid, may be administered to relieve complex
regional pain syndrome, such as complex regional pain syndrome type I (CRPS-I), complex …
Neuroimaging-based biomarker discovery and validation.
CW Woo, TD Wager, CW Woo – PAIN, 2015
… Neuroimage 2008;40(2):788-795. [11] Geha PY, Baliki MN, Harden RN, Bauer WR, Parrish
TB, Apkarian AV. The brain in chronic CRPS pain: abnormal gray-white matter interactions
in emotional and autonomic regions. Neuron 2008;60(4):570-581. …
[PDF] IASP Interprofessional Pain Curriculum Outline
N Kariuki, J Miró, L Niemi-Murola, G Ochoa…
… Primary Lesion Peripheral • degenerative disc disease with radiculopathy in neck and low back •
peripheral neuropathies (diabetes, cancer, alcohol, HIV) • post herpetic neuralgia • acute disc
herniation with radiculopathy • complex regional pain syndrome II (CRPS II) (causalgia …
Fibromyalgia
Inflammatory Allied Conditions
MA Oliveira, A Ciechomska – Musculoskeletal Ultrasonography in Rheumatic …, 2015
… biopsies. Whereas in fibromyalgia, there are conflicting data about the utility of US,
and if used, it is mainly to exclude other causes of pain. … XXXIX. Sonographic assessment
of hip in fibromyalgia patients. Clin Exp Rheumatol 30: pp. …
Childhood adversity and illness progression in bipolar disorder
J Bücker, M Kauer-Sant’Anna, LN Yatham – Neuroprogression and Staging in Bipolar …, 2015
… BD patients with a history of childhood adversity also seem to report comorbidity with numerous
medical conditions, including allergies, arthritis, asthma, chronic fatigue syndrome, chronic
menstrual irregularities, fibromyalgia, head injury, hypotension, irrit- able bowel syndrome …
The Use of Motivational Interviewing in Physical Therapy Education and Practice: Empowering Patients Through Effective Self-Management
RM Pignataro, PT James Huddleston – Journal of Physical Therapy Education, 2015
… been successfully employed in promoting adherence to a walking program in patients receiving
chemotherapy for breast cancer,42 in improving health promotion behaviors among people with
coronary risk factors,42 and in promoting exercise in patients with fibromyalgia.39 In …
[PDF] Temporomandibular Joint Dysfunction
J Poduval – JMR, 2015
… J Craniomandib Disord 1992, 6:301-355. 4. Truta MP, Santucci ET, Donlon WC. Head
and Neck fibromyalgia and temporomandibular arthralgia. In: Jacobson AL, Donlon WC,
(Eds). Headache and Facial Pain. New York: Raven, 1990:141. …
From the Desk of Dr. Karl ROS Johnson, DC…..
ROS Karl
… Intentional musings of a unique Shelby Township Michigan Chiropractic Physician dedicated
to helping people find solutions to improving their health by rooting out causes to chronic
conditions such as fibromyalgia, thyroid disorder symptoms, balance disorders, migraines …
Ankylosing Spondylitis
M Backhaus, Y El Miedany – Musculoskeletal Ultrasonography in Rheumatic …, 2015
… Beside spondyloarthritis patients, enthesitis have been reported among athletes
as a consequence of traumatic injuries. Distinguishing fibromyalgia tender points
from enthesitis is another important challenge to be considered. …
[HTML] Development of a Learning-Oriented Computer Assisted Instruction Designed to Improve Skills in the Clinical Assessment of the Nutritional Status: A Pilot Evaluation
LG de Diego, M Cuervo, JA Martínez – 2015
Advertisement. …
[PDF] P1. Community-Clinical Linkages in the WISEWOMAN Program
K Ahmed, I Vaid, D May, D Manheim – JOURNAL OF WOMEN’S HEALTH, 2015
… this study. Of the women patients, 361 reported a history of hysterectomy. A
comparison group consisted of 361 patients with a primary diagnosis of headache
or fibromyalgia without history of hysterectomy. Patients completed …
[HTML] The Hot Sauce: Peppers and Fat Loss
VR Prisk
… Aside from deterrence of muggers and bets between friends, there are many therapeutic
applications of capsaicin. Capsaicin creams, which desensitize nerves over time, are used
to treat neuropathy, shingles, psoriasis, arthritis pain and fibromyalgia. …
[PDF] TEMPORALITY AND INFORMATION WORK IN BONE MARROW TRANSPLANT
AG Büyüktür – 2015
… al., 2010; Hubbard et al., 2010), motor neuron disease (eg Locock et al., 2009), chronic fatigue
syndrome and fibromyalgia (eg Asbring, 2001), HIV infection (eg Anderson et al., 2010; Wilson,
2007), and multiple sclerosis (eg Green et al., 2007), among others. …
34 Fibromyalgia, Chronic Fatigue, Functional Disorders, and Vaccination: Where Do We Stand?
JN Ablin, D Buskila – Vaccines and Autoimmunity, 2015
Gender and psychosocial context as determinants of fibromyalgia symptoms (fibromyalgia research criteria) in young adults from the general population
S Lourenço, L Costa, AM Rodrigues, F Carnide… – Rheumatology, 2015
Objective. To quantify the prevalence of FM (FM research criteria), to describe its
components—symptom severity score (SSS) and widespread pain index (WPI)—and to
identify biopsychosocial predictors of the severity of SSS as well as WPI using a …
Fibromyalgia and the Risk of a Subsequent Motor Vehicle Crash
DA Redelmeier, JD Zung, D Thiruchelvam… – The Journal of …, 2015
Objective Motor vehicle crashes are a widespread contributor to mortality and morbidity,
sometimes related to medically unfit motorists. We tested whether patients diagnosed with
fibromyalgia (FM) have an increased risk of a subsequent serious motor vehicle crash. …
Association of antithyroid peroxidase antibody with fibromyalgia in rheumatoid arthritis
J Ahmad, H Blumen, CE Tagoe – Rheumatology International, 2015
Abstract To investigate how autoimmune thyroiditis (ATD) affects the clinical presentation of
established rheumatoid arthritis (RA) with particular reference to fibromyalgia and chronic
widespread pain (CWP). A cohort of 204 patients with RA for whom the presence or …
Association between fibromyalgia and thyroid autoimmunity
N Shirzad, S Movassaghi, H Karmostaji, F Esfahanian… – 2015
Fibromyalgia is a disorder characterised by fatigue, generalised body pain and cognitive
symptoms, and the aetiology has not been clearly described. Because similar symptoms are
frequently found in Hashimoto’s thyroiditis and there is not an optimal response to the …
COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESTLESS LEG SYNDROME AND FIBROMYALGIA
M Kandula – US Patent 20,150,133,408, 2015
Abstract: The invention relates to the compounds of formula I or its pharmaceutical
acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates
thereof. The pharmaceutical compositions comprising an effective amount of compounds …
[PDF] REVISTA BRASILEIRA DE REUMATOLOGIA
SB de Lorena, MCC de Lima, A Ranzolin, ÂLBP Duarte – rev bras reumatol, 2015
… Review article Effects of muscle stretching exercises in the treatment of fibromyalgia: a systematic
review … articleinfo Article history: Received 16 March 2014 Accepted 17 August 2014 Available
online 6 January 2015 Keywords: Fibromyalgia Stretching Physiotherapy abstract …
36 Infections, Vaccinations, and Chronic Fatigue Syndrome
H Mahagna, N Mahroum, H Amital – Vaccines and Autoimmunity, 2015
COMPOSITIONS AND METHODS FOR INDUCING MYOBLAST DIFFERENTIATION AND MYOTUBE FORMATION
MP Czech, M Wang – US Patent 20,150,133,520, 2015
… 12. The method of claim 11, wherein the muscle disorder is selected from the group consisting
of: muscle atrophy, muscle weakness, myopathy, chronic fatigue syndrome, fibromyalgia, muscular
dystrophy, fatigue fibromyalgia, spinal muscle atrophy, distal muscular dystrophy …
27 Aluminum Particle Biopersistence, Systemic Transport, and Long-Term Safety: Macrophagic Myofasciitis and Beyond
RK Gherardi, J Cadusseau, FJ Authier – Vaccines and Autoimmunity, 2015