by admin | Apr 13, 2015 | Uncategorized
Scientific breakthroughs happen every day! In an effort to help our patients stay up to speed on the most cutting edge treatment options available for them, our scientists monitor current research and publish weekly research updates (below).
If you’d like to make an appointment with Dr. Hanna to discuss your treatment options, please contact us.
Ketamine
Wastewater analysis to monitor spatial and temporal patterns of use of two synthetic recreational drugs, ketamine and mephedrone, in Italy
S Castiglioni, A Borsotti, I Senta, E Zuccato – Environmental Science & Technology, 2015
Wastewater analysis was applied in a four-year monitoring study to assess temporal and
spatial patterns of ketamine and mephedrone use in the general population in Italy.
Composite raw wastewater samples were collected from sewage treatment plants (STPs) …
The use of ketamine as an antidepressant: a systematic review and meta‐analysis
CM Coyle, KR Laws – Human Psychopharmacology: Clinical and …, 2015
Objective The current meta-analysis examines the effects of ketamine infusion on
depressive symptoms over time in major depressive disorder (MDD) and bipolar disorder
(BD). Methods Following a systematic review of the literature, data were extracted from 21 …
Intravenous Ketamine to Facilitate Non-Invasive Ventilation in a Patient with a Severe Asthma Exacerbation
E Kiureghian, JM Kowalski – The American Journal of Emergency Medicine, 2015
Background Despite advances in outpatient treatment and an improved understanding of
the pathophysiology, asthma continues to be a significant source of morbidity and mortality
in the United States. While there is certainly a component of chronic inflammation, the …
Perioperative low-dose ketamine improves postoperative analgesia following Cesarean delivery with general anesthesia
M Haliloglu, M Ozdemir, N Uzture, PO Cenksoy… – The Journal of Maternal- …, 2015
Abstract Objective: In this study, the effect of perioperative uses of low dose ketamine on
post-operative wound pain and analgesic consumption in patients undergoing elective
Cesarean section was evaluated. Methods: In randomized, double blind clinical trial, 52 …
The Clinical Effect of Fentanyl in Comparison with Ketamine in Analgesic Effect for Oncology Procedures in Children: A Randomized, Double-Blinded, Crossover Trial
C Monsereenusorn, P Rujkijyanont, C Traivaree – JOURNAL OF THE MEDICAL …, 2015
Material and Method: A randomized, double-blinded, crossover trial was conducted with 55 children
undergoing painful procedures (intrathecal chemotherapy and/or bone marrow
aspiration/biopsy). Patients were randomly assigned in a double-blinded fashion to …
Dexmedetomidine, Ketamine, and Midazolam for Oral Rehabilitation: A Case Report
BWS Kim, RM Peskin – Anesthesia Progress, 2015
Abstract Intravenous sedation is frequently provided by anesthesiologists for phobic patients
undergoing elective dental treatment in outpatient settings. Propofol is one of the most
commonly used anesthetic agents that can result in apnea and respiratory depression, …
Ketamine May Be Related to Minor Troponin Elevations in Children Undergoing Minor Procedures in Emergency Department
M Serinken, C Eken – The American Journal of Emergency Medicine, 2015
Objective Ketamine is a dissociative anesthetic agent that has an increased frequency of
usage in the last years particularly in emergency departments. In the present study, we
aimed to determine whether ketamine is related to myocardial injury in children …
Anesthesia and neuromonitoring
EN Menga, GJ Spessot, JA Bendo – Seminars in Spine Surgery, 2015
… Commonly used intravenous anesthetics include propofol, dexmedetomidine, etomidate,
barbiturates, ketamine, and benzodiazepines. … Using a canine model, Glassman et al. 13 reported
consistent and reproducible TcMEPs with ketamine and etomidate. …
Inflammatory Biomarkers as Differential Predictors of Antidepressant Response
K Hashimoto – International Journal of Molecular Sciences, 2015
… situation. This article discusses inflammatory molecules as predictive biomarkers
for antidepressant responses to several classes of antidepressants, including the
N-methyl-d-aspartate (NMDA) receptor antagonist ketamine. …
Spinal cord neuron inputs to the cuneate nucleus that partially survive dorsal column lesions: A pathway that could contribute to recovery after spinal cord injury
CC Liao, GE DiCarlo, OA Gharbawie, HX Qi, JH Kaas – Journal of Comparative …, 2015
… tranquilized with an intramuscular injection (IM) of ketamine hydrochloride (10-25 mg/ kg, IM)
and Page 4 of 55 John Wiley & Sons Journal of Comparative Neurology … In preparation for the
injection, each monkey was tranquilized with ketamine hydrochloride (10mg/kg, …
Radiofrequency Ablation (RFA)
[PDF] Comparison of amiodarone and propafenone for maintenance of stable sinus rhythm after bipolar radiofrequency ablation combined with a mitral valve procedure in …
Y Beşir, O Gökalp, U Yetkin, E Çelik, H İner, B Lafçı… – Türk Göğüs Kalp Damar …, 2015
ABSTRACT Background: This study aims to examine the effects of amiodarone versus
propafenone for maintenance of stable sinus rhythm after left atrial bipolar radiofrequency
ablation combined with a mitral valve procedure in patients with mitral valve disease and …
New Technologies and Approaches to Endoscopic Control of Gastrointestinal Bleeding
LL Fujii-Lau, LMWK Song, MJ Levy – Gastrointestinal Endoscopy Clinics of North …, 2015
… Radiofrequency Ablation. Technique. Focal radiofrequency ablation (RFA) catheters
(Barrx; Covidien, Mansfield, MA) have been used to treat GI bleeding in the setting of
gastric antral vascular ectasia (GAVE) (Fig. 3) and radiation proctitis. …
Dichorionic triplet pregnancies: risk of miscarriage and severe preterm delivery with fetal reduction versus expectant management. Outcomes of a cohort study and …
M Morlando, L Ferrara, F D’Antonio, A Lawin‐O’Brien… – BJOG: An International …, 2015
… Ultrasound-guided laser ablation or radiofrequency ablation of the pelvic vessels of one
of the monochorionic fetuses was used in all cases of reduction from three to two fetuses
for selective reduction of one of the two monochorionic fetuses. …
Interventional MR elastography for MRI‐guided percutaneous procedures
N Corbin, J Vappou, E Breton, Q Boehler, L Barbé… – Magnetic Resonance in …, 2015
… [27] showed that the Young’s modulus of the treated liver tumor in swine increases from 6 to 40
kPa approximately during a 5 min-long radiofrequency ablation by providing elastographic
information every 30 s. The monitoring of thermal ablations with MRE is limited by the …
[HTML] Editorials & Opinions
JP Tasto – Am J Orthop, 2015
… Published December 2014. Accessed March 6, 2015. « Back To: Editorials & Opinions. Did
you miss this content? Cutaneous Burn Caused by Radiofrequency Ablation Probe During
Shoulder Arthroscopy. More From The American Journal of Orthopedics …
Hysteroscopy and heavy menstrual bleeding (to cover TCRE and second generation endometrial ablation)
M Bongers – Best Practice & Research Clinical Obstetrics & …, 2015
… cryo-ablation (HerOption™, Cooper Surgical, Trumbull, CT) [14], and bipolar radiofrequency
(Novasure™, Hologic … The difference between the first and the second-generation endometrial
ablation are several. … Under direct vision the total endometrium can be resected or ablated. …
Atrioesophageal fistula and pneumocephalus after pulmonary vein isolation
BD Wilson, JH Morshedzadeh – European Heart Journal-Cardiovascular Imaging, 2015
… Catheter radiofrequency ablation of atrial fibrillation is an increasingly common procedure,
and atrioesophageal fistula is a rare and often fatal complication. High clinical suspicion,
rapid diagnosis, and surgical therapy may prevent death. …
Gastroparesis as a Complication of Atrial Fibrillation Ablation
T Aksu, S Golcuk, TE Guler, K Yalin, I Erden – The American Journal of Cardiology, 2015
… ventricular ejection fraction, M=male; N=normal; PIN=patient identification number; R=
radiofrequency. … more reasonable avoiding cryo-energy at lower temperatures while ablating
inferior PVs … The most possible mechanism of gastroparesis related with AF ablation is collateral …
The impact of left atrial surface area and the second generation cryoballoon on clinical outcome of atrial fibrillation cryoablation
H Greiss, A Berkowitsch, M Wojcik, S Zaltsberg… – Pacing and Clinical …, 2015
… 16 Impact of LA area on outcome In our previous studies performed on patients ablated with CB,
we found NLA area to be predictive for outcome, but absolute LA area was not predictive. … Raviele
A, Themistoclakis S, Rossillo A, Bonso A, Natale A. Radiofrequency ablation …
Persistence of Phrenic Nerve Palsy Following 28 mm Cryoballoon Ablation: A Four Year Single Center Experience
Y Saitoh, G Irfan, G Ciconte, G Mugnai, J Sieira… – Pacing and Clinical …, 2015
… Great attention must be paid when ablating with the large 28 mm CB2 due to the … large cryoballoon
for treatment of paroxysmal and persistent atrial fibrillation: medium-term outcomes and
non-randomised comparison with pulmonary venous isolation by radiofrequency ablation. …
Complex Regional Pain Syndrome (CRPS/RSD)
Hydromorphone for neuropathic pain in adults
D Aldington, P Cole, R Knaggs, C Stannard, S Derry… – The Cochrane Library, 2015
… Types of participants Studies will include adults aged 18 years and above with one or more chronic
neuropathic pain condition including (but not lim- ited to): 1. cancer-related neuropathy; 2. central
neuropathic pain; 3. complex regional pain syndrome (CRPS) Type II; 4. human …
Fentanyl for neuropathic pain in adults
S Derry, R Knaggs, PJ Wiffen, C Stannard, D Aldington… – The Cochrane Library, 2015
… Types of participants Studies will include adults aged 18 years and above with one or more chronic
neuropathic pain condition including (but not lim- ited to): 1. cancer-related neuropathy; 2. central
neuropathic pain; 3. complex regional pain syndrome (CRPS) Type II; 4. human …
The role of glia in the spinal cord in neuropathic and inflammatory pain
EA Old, AK Clark, M Malcangio – Pain Control, 2015
… microglia pool. Nat Neurosci 14: pp. 1142-1149; Alexander, GM, Rijn, MA, Hilten,
JJ, Perreault, MJ, Schwartzman, RJ (2005) Changes in cerebrospinal fluid levels
of pro-inflammatory cytokines in CRPS. Pain 116: pp. 213-219; …
[HTML] To study the incidence and risk factors of early onset neonatal sepsis in an out born neonatal intensive care unit of India
M Jajoo, K Kapoor, LK Garg, V Manchanda, SK Mittal – Journal of Clinical …, 2015
… [6] Screening tests such as total and differential leukocyte counts, band cells, absolute neutrophil
counts (ANCs), and rapid immunological techniques like C-reactive proteins (CRPs) assays may
help in the diagnosis of septicemia; however, they lack the capacity to detect …
[PDF] Psychological Aspects of Reflex Sympathetic Dystrophy (RSD) Complex Regional Pain Syndrome (CRPS)
H Hooshmand, EM Phillips, FL Vero Beach
Abstract. Reflex sympathetic dystrophy (RSD) or complex regional pain syndrome (CRPS) is
a complex form of neuropathic pain associated with hyperpathia; neurovascular instability;
neuroinflammation; and limbic system dysfunction. As the condition becomes chronic, the …
[PDF] COMPLEX REGIONAL PAIN SYNDROME (CRPS) REFLEX SYMPATHETIC DYSTROPHY (RSD) DIAGNOSIS AND MANAGEMENT PROTOCOL
H Hooshmand, EM Phillips, FL Vero Beach
Complex Regional Pain Syndrome (CRPS)/Reflex Sympathetic Dystrophy (RSD) is a
disease that usually starts after a relatively minor trauma. In the early stages there is a
sympathetic component in the development of the disease, but with passage of time, quite …
[PDF] Complex Regional Pain Syndrome (CRPS) and Sympathectomy
H Hooshmand, EM Phillips
Abstract. Sympathectomy may provide temporary pain relief, but after a few weeks to months
it loses its effect. Sympathectomy and the application of Chemical Sympathectomy
(neurolytic agents eg, phenol, alcohol, etc.) should be limited to patients with life …
[PDF] REPETITIVE STRAIN INJURY (RSI) DIAGNOSIS AND TREATMENT
H Hooshmand, EM Phillips, FL Vero Beach
… Careful history taking, neurological evaluation, along with such tests as quantitative
sensory testing (QST) and infrared thermal imaging (ITI) is helpful to differentiate RSI
from other causes of complex regional pain syndrome (CRPS). …
Polysomnographic Characteristics in Nonmalignant Chronic Pain Populations: A Review of Controlled Studies
MF Bjurstrom, MR Irwin – Sleep Medicine Reviews, 2015
… Glossary of terms. AHI apnea/hypopnea index. ArI arousal index. BDNF brain-derived neurotrophic
factor. CNS central nervous system. CRPS complex regional pain syndrome,. CWP chronic
widespread pain. EEG electroencephalography. FM fibromyalgia. HC healthy controls. …
Fibromyalgia
Validation and cross-cultural adaptation of the ‘Fibromyalgia Participation Questionnaire’to the Spanish population: study protocol
M Gomez-Calvente, I Medina-Porqueres… – Rheumatology International, 2015
Abstract There are few high-quality instruments to evaluate the participation and social
functioning of fibromyalgia patients. The Fibromyalgia Participation Questionnaire (FPQ) is a
questionnaire that evaluates these aspects with high reliability and validity in its German …
What Constitutes Appropriate Treatment of Post-Lyme Disease Symptoms and Other Pain and Fatigue Syndromes?
AC Steere, SL Arvikar – Clinical Infectious Diseases, 2015
… This chronic syndrome, which sometimes meets criteria for fibromyalgia or chronic fatigue
syndrome, is not specific for Lyme disease [8]. Such symptoms may follow other infections or
physical or emotional trauma, or the inciting cause may not be apparent. …
Central sensitization in humans: assessment and pharmacology
L Arendt-Nielsen – Pain Control, 2015
… J Pain 4: pp. 372-380; Balasubramaniam, R, Leeuw, R, Zhu, H, Nickerson, RB, Okeson, JP,
Carlson, CR (2007) Prevalence of temporomandibular disorders in fibromyalgia and failed
back syndrome patients: a blinded prospective comparison study. …
Chronic pain and the adaptive significance of positive emotions.
AD Ong, AJ Zautra, MC Reid – 2015
… Indeed, such in- terventions may prove to be particularly important for patients with specific chronic
pain conditions, such as fibromyalgia, who show a core affective disturbance that is characterized
by an overall deficit in posi- tive emotion (Finan, Zautra, & Davis, 2009). …
Chronic widespread pain: clinical comorbidities and psychological correlates Running title: Genetics of CWP
A Burri, S Ogata, J Vehof, FMK Williams, B Box – 2015
… 3 1. Introduction Chronic widespread pain (CWP) is the cardinal symptom of fibromyalgia. … four
items pertaining to the “pain subscale” were drawn from the London Fibromyalgia Epidemiology
Symptom Screening questionnaire (LFESSQ).[34] The four items ask about pain …
Hydromorphone for neuropathic pain in adults
D Aldington, P Cole, R Knaggs, C Stannard, S Derry… – The Cochrane Library, 2015
… Pharmacological treatment of fibromyalgia. … Journal of Pain 2008;9(2): 105–21. [DOI:
10.1016/j.jpain.2007.09.005] Gaskell 2014 Gaskell H, Moore RA, Derry, S, Stannard
C. Oxycodone for neuropathic pain and fibromyalgia in adults. …
Tarasoff’s catch-22.
SR Huey – 2015
… REFERENCES Davis, MC, & Zautra, AJ (2013). An online mindfulness intervention targeting
socioemo- tional regulation in fibromyalgia: Results of a randomized controlled trial. … Daily affect
relations in fibromyalgia patients reveal positive affective disturbance. …
Fentanyl for neuropathic pain in adults
S Derry, R Knaggs, PJ Wiffen, C Stannard, D Aldington… – The Cochrane Library, 2015
… Pharmacological treatment of fibromyalgia. … Durogesic® DTrans. www.medicines.org.uk/EMC/
medicine/17088/ (accessed 16 December 2014). Gaskell 2014 Gaskell H, Moore RA, Derry, S,
Stannard C. Oxycodone for neuropathic pain and fibromyalgia in adults. …
Polysomnographic Characteristics in Nonmalignant Chronic Pain Populations: A Review of Controlled Studies
MF Bjurstrom, MR Irwin – Sleep Medicine Reviews, 2015
… CNS central nervous system. CRPS complex regional pain syndrome,. CWP chronic widespread
pain. EEG electroencephalography. FM fibromyalgia. HC healthy controls. IL interleukin. MFP
myofascial pain. NREM non-rapid-eye-movement. NSM non-sleep migraine. OA …
Methods to Measure Peripheral and Central Pain Sensitization Using Quantitative Sensory Testing: A Focus on Individuals with Low Back Pain
AR Starkweather, A Heineman, S Storey, G Rubia… – Applied Nursing Research, 2015
… In order to evaluate and compare centralized mechanisms, the QST protocol of the German
Research Network on Neuropathic Pain was used in a group of 21 patient with fibromyalgia
(mean duration 13.4 years), 23 individuals with chronic back pain (mean duration 15.9 years …
by admin | Apr 9, 2015 | Uncategorized
Simple lifestyle changes and natural approaches can often make a difference when you’re seeking migraine relief. Here are 8 self-care techniques that may help…
What do you do once you feel the throbbing pain and other symptoms that accompany migraine headaches?
Whether you run for a dark room or to the medicine cabinet, you might consider one more approach: self-care therapies. They can ease pain and reduce the frequency of migraine attacks.
Migraines are vascular headaches, meaning they’re triggered by the temporary narrowing of blood vessels in your head. This reduces the flow of blood-transporting oxygen to your brain, producing many unpleasant symptoms. They can include severe pain, light and noise sensitivity, auras, nausea and vomiting. Often, the pain is felt on just one side of the head, according to the National Institute of Neurological Diseases and Stroke (NINDS).
Many migraine patients use self-care techniques along with medication to relieve migraine symptoms. In fact, about half of patients reported using at least one non-pharmaceutical therapy to self-treat their migraines, according to a 2013 study published in Headache: The Journal of Head and Face Pain.
Here are 8 self-care techniques that experts say may help.
1. Keep a migraine diary.
You might think that migraines are unpredictable. But 70% of migraine sufferers experience early warning symptoms that may be identified with a headache diary, according to a 2009 Georgia State University study.
“Keep a really good diary or journal,” advises Sheena Aurora, M.D., clinical professor of Neurology and Neurological Sciences at the Stanford University School of Medicine in California.
“This is where you can log your medication use, how often you’re having headaches, your diet and any other triggers or patterns that you see,” she says.
Share this information with your doctor at each appointment.
2. Work out regularly.
Moderate exercise may reduce frequency, intensity and length of migraine attacks, according to a 2011 study in Cephalalgia, a peer-reviewed medical journal.
“Take a walk in a casual, yoga-like fashion for 30 minutes a day – or even a 15-minute outdoor walk on your lunch break – to [give] your body the benefits of modest exercise and your brain space and relief,” suggests Richard P. Kraig, M.D., Ph.D., director of the migraine headache clinic at the University of Chicago Medicine.
This process will help release stress, improve concentration and reduce excitability or tension, Dr. Kraig says.
“We’ve found that exercise, plus environmental enrichment [spending time in pleasant or interesting surroundings], makes the brain stronger against migraines,” he says.
3. Snuggle up with your partner.
Many people avoid sexual activity during migraine attacks. But engaging in it may actually lead to partial or complete relief, German researchers found in 2013.
That’s because physical intimacy produces a rush of feel-good hormones called endorphins, your body’s own natural painkillers.
“Although the science on this is limited, it’s intriguing that it might work for some individuals,” Dr. Aurora says. “I’ve actually heard about this approach being used by patients.”
4. Consider supplements.
Migraines are sometimes caused by vitamin or mineral deficiencies or imbalances, and many patients who take riboflavin or magnesium supplements find relief with minimal side effects, according to a 2012 study published in the journal Biological Trace Elements Research.
Ask your doctor before taking any supplements.
Taking 50 mg of riboflavin daily is enough to treat mild migraines; 500 mg of magnesium has been shown to reduce migraine frequency and severity, Dr. Aurora says.
“I tell those with regular migraines to start taking a supplement and keep a log to see if certain symptoms subside,” she adds.
5. Clean up your sleep act.
If you often wake up with a headache, this is a sign that your sleep patterns may be the culprit.
In fact, the onset of nearly half of all migraines occurs between 4 and 9 a.m., according to the American Headache Society Committee on Headache Education, a nonprofit educational resource for health professionals.
Being sleep deprived, over-sleeping or suffering from sleep disturbances, such as obstructive sleep apnea or restless leg syndrome, may trigger a migraine, according to the American Migraine Foundation.
In turn, headache sufferers are also at higher risk of developing a sleep disorder.
Establish regular sleep hours to lower your chances of experiencing sleep-related migraines.
“Stability with sleep is crucial with migraines,” says Dr. Aurora. “Going to bed and getting up at the same time each day is generally more important than the total number of hours you’re sleeping at night.”
6. Practice mindfulness meditation or yoga.
One of the biggest migraine triggers is stress, but it’s often the hardest one to manage. Luckily, a variety of stress-reduction techniques can help.
Adults found relief from migraine symptoms when they participated in 8 weeks of a mindfulness-based stress reduction program, according to a 2014 study conducted at Wake Forest Baptist Medical Center in Winston-Salem, N.C. After using meditation and yoga principles, subjects reported fewer migraine attacks, less pain, reduced stress, anxiety and disability, and a better quality of life.
People with migraines “are often anxious people,” Dr. Kraig says. “Since migraines and anxiety are [associated medical conditions], finding a way to relax, like yoga, will help calm the winding up of the string of stressors that can trigger migraine attacks.”
7. Get a massage.
Massage can be an effective complementary therapy for treating migraines, especially those brought on by stress or sleep issues.
“Massage works mostly as a de-stressor,” explains Dr. Aurora. “As women get older, we hold more pressure in our necks, and that seems to be a hot-spot trigger for migraines.”
The neck-brain stem connection stores tension and pressure that can be released with physical manipulation from a massage.
You don’t need a daily massage, but the healing touch might be just enough to keep symptoms at bay when you feel the warning signs of a migraine attack. Just make sure you choose a licensed massage therapist.
8. Learn biofeedback.
Biofeedback, a pain management intervention, may work to lessen the stress and muscle tension that can trigger migraine, according to a 2010 study reported in Cleveland Clinic Journal of Medicine.
Although there are home programs available, biofeedback is traditionally done with a psychologist who uses a computer monitor device that illustrates what happens when your brain responds to stress. The aim is to help patients learn to control specific body functions, including breathing rate, muscle tension and heart rate.
“It’s very valuable to learn biofeedback and muscle relaxation with a practitioner first and be taught the techniques properly,” says Dr. Aurora. “Then, they can be effective self-care tools that you may use on your own.”
